1.Effect of Human Seminal Plasma on Cytokine Prodection and Induction of Active Systemic Anaphylaxis in Mice.
Tai You HA ; Jae Seung PARK ; Yoo Seung KO ; Yong Ho LEE ; Young Kyung PARK
Korean Journal of Immunology 1999;21(3):209-219
Human seminal plasrna (HSP) is mixture of secretion derived from various glands associated with male reproductive tract which comprises approximately 80-90% of the volume of normal ejaculate. The present study was undertaken in an effort to explore the effect of HSP pretreatment on the production of IL-1B, TNF-a and IL-12, in mice, and to investigate if HSP may cause to induce active systemic anaphylaxis (ASA) in mice. In addition, effects of HSP pretreatment on contact hypersensitivity to trinitrochlorobenzene (TNCB), antibody response to polyvinylpyrroridone (PVP), a thymus-independent antigen and on ASA induced by egg albumin (OVA) were also studied in this study. For the experiments of contact hypersensitivity, antibody response and cytokine production, mice were pretreated i.p. daily with 0.3ml of HSP or sterile saline alone (control) for 3 consecutive days before antigen sensitization or lipopolysaccharide injection for the cytokine induction. For the experiments of OVA- induced anaphylaxis, mice were pretreated by a single s.c. injection of HSP 0.3ml per mouse before sensitization. For induction of ASA in mice by HSP, a group of mice were sensitized i.p. 2 consecutive days with 0.3ml of HSP and one day with 0.3 ml of HSP plus 2x10(9) B. pertussis and 1.0 mg of alum (schedule A) or another group of mice were sensitized i.p. with a single i.p. injection of 0.3 ml of HSP with 2x10' B. pertussis and 1.0 mg of alum (schedule B). All sensitized and unsensitized control mice were challenged i.v. with 0.2ml of HSP 14 days after HSP sensitization, and mortality were observed. It was found that HSP pretreatment inhibited the production of IL-lB, TNF-a and IL-12, and also inhibited OVA-induced ASA, contact hypersensitivity to TNCB and anti-PVP antibody production. Interestingly, ASA was induced by HSP irrespective of the applied sensitization schedule. Taken together, this study may provide the direct evidences that HSP may inhibit the production of IL-1B, TNF-a and IL-12 and this may be the first to show the induction of ASA by HSP in mice.
Anaphylaxis*
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Animals
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Antibody Formation
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Appointments and Schedules
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Dermatitis, Contact
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Humans*
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Interleukin-12
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Male
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Mice*
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Mortality
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Ovum
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Picryl Chloride
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Semen*
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Whooping Cough
2.A Case of Onychomycosis due to Hortaea werneckii.
Dong Yeob KO ; Seung Min HA ; Su Young JEON ; Ki Hoon SONG ; Ki Ho KIM
Korean Journal of Dermatology 2013;51(4):297-298
No abstract available.
Onychomycosis
3.A Case of Onychomycosis Caused by Candida guilliermondii.
Dong Yeob KO ; Seung Min HA ; Su Young JEON ; Ki Hoon SONG ; Ki Ho KIM
Korean Journal of Dermatology 2013;51(4):296-297
No abstract available.
Candida
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Onychomycosis
4.Dilated Pore Nevus.
Su Young JEON ; Seung Min HA ; Dong Yeob KO ; Ki Hoon SONG ; Ki Ho KIM
Korean Journal of Dermatology 2012;50(11):1009-1010
No abstract available.
Nevus
5.A study of histomorphological change of curved root canal preparation using GT rotary file, profile and stainless steel K-file.
Journal of Korean Academy of Conservative Dentistry 2002;27(6):612-621
The purpose of this study was to compare the histomorphological change of curved root canal preparation using GT rotary File, Profile .04 taper and stainless steel K-file. 45 mesial canals(over 20 degree) of extracted human mandibular first molars were mounted in resin using a modified Bramante muffle system and divided into three groups. The roots were cross-sectioned at 2.5mm, 5mm and 8mm levels from apical foramen. Tracings of the canals were made from preinstrumentation pictures of the cross section. The canals were prepared using a step-back technique with stainless steel K file(group 1), Profile .04 taper rotary file(group 2) and GT rotary file(group 3). Tracings of the prepared canals were made from postinstrumentation picture. Canal centring ratio, amount of transportation, area of dentin removed and shape of canal were measured and statistically were evaluated with Student-Newman-Keuls test using Sigma Stat(Jandel Scientific Software, USA). The results were as followings: 1. Amount of transportation of group 2 was the lowest at apical part, but there was no statistical difference. The direction of transportation was the outside of curvature at apical part. 2. Centering ratio at the apical part of group 1 was the highest, and there was statistical differences between apical and middle part, apical and coronal part(p<0.05). Centering ratio at the middle part of group 3 was the lowest, and there was statistical difference between apical and middle part(p<0.05). Centring ratio of group 2 was the lowest at apical part, but there was no statistical difference. 3. Amount of dentin removed of group 1 was the highest at coronal, middle and apical part among three groups, and there was statistical difference(p<0.05). 4. The majority of the cross-sectioned canal shape after instrumentation were irregular at coronal, middle and apical part. But there are more number of round shaped canals at group 3 than other group.
Dental Pulp Cavity
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Dentin
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Humans
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Molar
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Root Canal Preparation
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Stainless Steel
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Tooth Apex
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Transportation
6.White Piedra of Scalp Hair Caused by Trichosporon asahii.
Dong Yeob KO ; Seung Min HA ; Su Young JEON ; Ki Hoon SONG ; Ki Ho KIM
Korean Journal of Dermatology 2013;51(3):228-229
No abstract available.
Hair
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Humans
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Piedra
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Scalp
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Trichosporon
7.Ultrasonography and Ultrasound-guided Interventions of the Shoulder.
Sang Ho MOON ; Kwang Pyo KO ; Seung Il BAEK ; Song LEE
Clinics in Shoulder and Elbow 2015;18(3):172-193
Nowadays shoulder ultrasound is commonly used in the assessment of shoulder diseases and is as accurate as magnetic resonance imaging in the detection of several pathologies. Operator dependence is the main disadvantage of shoulder ultrasound. After adhering to a strict examination protocol, good knowledge of normal anatomy and pathologic processes and an awareness of common pitfalls, it can be used as a focused examination providing rapid, real-time diagnosis, and treatment by ultrasound-guided interventions in desired clinical situations. Also shoulder ultrasound can help the surgeon decide whether treatment will be surgical or nonsurgical. If arthroscopy is planned, sonographic findings help to counsel patients regarding surgical and functional outcomes. If a nonsurgical approach is indicated, ultrasound can be used to follow patients. This review article presents the examination techniques, the normal sonographic appearances and the main pathologic conditions found in shoulder ultrasound. And also addresses a simplified approach to scanning and ultrasound-guided intervention. Knowledge of optimal techniques, normal anatomy, dynamic maneuvers, and pathologic conditions is essential for optimal performance and interpretation of images.
Arthroscopy
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Diagnosis
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Humans
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Magnetic Resonance Imaging
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Pathologic Processes
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Pathology
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Shoulder*
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Ultrasonography*
8.CT findings in recurrent pyogenic cholangitis.
Seung Hye JUNG ; Jae Hoon LIM ; Young Tae KO ; Dong Ho LEE
Journal of the Korean Radiological Society 1991;27(4):555-558
No abstract available.
Cholangitis*
9.Time-Dependent Diagnostic Value of TROPT(R)TnT Rapid Assay in Patients with Ischemic Chest Pain.
Dae Kon SOHN ; Jae Wook KO ; Seung Ho KIM ; Cheol Joo LEE
Journal of the Korean Society of Emergency Medicine 1998;9(2):240-247
A prospective study was carried out to evaluate the validity of TROPT troponin T rapid assay in early diagnosis of acute myocardial infarction(AMI) in patients with ischemic chest pain, in comparison with conventional diagnostic tools such as serum troponin T(c-TnT) level, creatine Kinase(CK), CK-MB level and initial EKG finding. The study was performed at the emergency department(ED) of Yong Dong Severance hospital from March 1st 1996 to February 28th 1997. One hundred eighty one patients visiting ED with chief complaint of atraumatic chest pain within 24 hours of visit were eligible for the study. Those who lacked enough data collection and those who had chest paint of noncardiac origin and EKG of PSVT were excluded from the study. The overall study population was a total of 131 patients. Initial EKG, TROPT rapid assay, CK, CK-MB and c-TnT level were obtained simultaneously. Diagnosis of AMI was made according to the international diagnostic criteria for AMI. Of the 131 patients 61 patients(46.6%) were diagnosed as AMI. Within 4 hours of their symptom onset, initial EKG showed the highest sensitivity(63.2%) whereas the sensitivities of TROPT rapid assay, c-TnT, CK and CK-MB were poor(0-0.7%). From 4-8 hours, the sensitivities of c-TnT, CK and CK-MB were higher than that of TROPT rapid assay(80% vs. 30%). The sensitivites of TROPT rapid assay, c-TnT, CK and CK-MB rose over time and reached 100% after 8 hours symptom onset. The specificities of the TROPT rapid assay, c-TnT, CK & CK-MB and EKG were all 100% within 8 hours after symptom onset. Discrepancy between TROPT rapid assay and c-TnT was noted in nine patients(6.9%). In this study TROPT rapid assay was valuable in the diagnosis of AMI after 8 hours of symptom onset.
Chest Pain*
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Creatine
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Data Collection
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Diagnosis
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Early Diagnosis
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Electrocardiography
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Emergencies
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Humans
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Paint
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Prospective Studies
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Thorax*
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Troponin
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Troponin T
10.A Clinical Experience on Pneumomediastinum: Report of 2 cases.
Jun Seok PARK ; Jai Woog KO ; Sang Won CHUNG ; Tae Sik HWANG ; Seung Ho KIM
Journal of the Korean Society of Emergency Medicine 1999;10(3):472-480
Pneumomediastinum is a relatively uncommon, infrequently reported entity, In the evaluation of these entity, it is important to exclude pathological causes, including Boerhaave's syndrome which carries a high mortality. Spontaneous pneumomediastinum is related to excessive intraalveolar pressure leading to rupture of perivascular alveoli in the setting of a Valsalva maneuver without communication to gut material. So, it has a benign self-limited course and rarely requires medical intervention. On the contrary, secondary pneumomediastinum caused by instrumental, traumatic, and spontaneous perforation of esophagus. Although the prognosis have been improved since the advent of broad-spectrum antibiotics and nutritional support, pneumomediastinum due to esophageal perforation still has a high morbidity and mortality. The most important prognostic factor is the time interval between perforation and initiation of therapy, and an awareness and a high clinical suspicion is critical in the early diagnosis and treatment. Recently, we have experienced 2 cases of pneumomediastinum, one case was spontaneous pneumomediastinum and the other may be caused by instrumental esophageal perforation. We report the clinical course of the patients with a current literature review.
Anti-Bacterial Agents
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Early Diagnosis
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Esophageal Perforation
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Esophagus
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Fibrinogen
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Humans
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Mediastinal Emphysema*
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Mortality
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Nutritional Support
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Prognosis
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Rupture
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Valsalva Maneuver