1.Differences of Spectral EEG Analysis and Prognosis Following Single Hemispheric Infarction and Hemorrhage in Striatocapsular Area.
Yong Tae KWAK ; Il Woo HAN ; Seung Han SUK
Journal of the Korean Geriatrics Society 2001;5(1):33-42
BACKGROUND: Vascular dementia is common cause of dementia, second to the dementia of Alzheimer desease. However in Asia and many developing countries, the incidence of vascular dementia exceeds that of Alzheimer's disease. Though many stroke-related factors related the nature of vascular injury, e.g. infarction and hemorrhage, have not assessed yet. Clarifying the difference of electroencephalograpy and clinical prognosis between infarction and hemorrhage, the aim of this study was to elucidate the role of nature of vascular injury. METHODS: to reduce confounding factors, the study population was restricted to the patients of single hemispheric striatocapsular infarction and hemorrhage saving cortex. On admission, we checked the KMMSE and FIM scores and using quantified EEG, we analyzed occipital peak frequency and the relative background alpha, theta and delta spectra power taken from 16 derivations by averaging twenty-2 -sec epoch in infarction, hemorrhage patients and elderly controls. After 6 months follow up, we compare the MMSE, FIM score between infarction and hemorrhage group. RESULTS: 1) Compared with infarction group, hemorrhage groups had a significantly bilateral lower occipital peak freqauency and background bilateral alpha spectra power. 2) In hemorrhage group, there is lower tendency in K-MMSE after 6 month follow up compared to infarction group. CONCLUSION: This study suggests that hemorrhage show more bilateral electrophysiological dysfunction than infarction group and possible grave prognosis for vascular dementia compared to infarction group.
Aged
;
Alzheimer Disease
;
Asia
;
Dementia
;
Dementia, Vascular
;
Developing Countries
;
Electroencephalography*
;
Follow-Up Studies
;
Hemorrhage*
;
Humans
;
Incidence
;
Infarction*
;
Prognosis*
;
Vascular System Injuries
2.A clinical experience for the restoration of flexion of elbow joint.
Kwang Suk LEE ; In Jung CHAE ; Seung Yup HAN
The Journal of the Korean Orthopaedic Association 1991;26(4):1314-1320
No abstract available.
Elbow Joint*
;
Elbow*
3.Homocysteine and risk of cerebrovascular lesions: The PRESENT project
Hyun Young Park ; Young Seo Kim ; Seung-Han Suk
Neurology Asia 2020;25(3):263-267
Objective: Cerebral white matter changes (WMCs) and silent brain infarcts (SBIs) are common
radiological findings in neurologically asymptomatic elderly people. Their presence is associated with
an increased risk of stroke or dementia. Homocysteine (Hcy) can cause atherosclerosis and may thus act
as a useful marker of stroke prior to symptom onset. This study aimed to evaluate the utility of Hcy as
a surrogate marker for early intervention for stroke in community-dwelling healthy elderly persons with
cerebrovascular lesions such as WMCs and SBIs. Methods: We assessed the relationship between the
Hcy level and presence of WMCs/SBIs on brain computed tomography (CT) in 554 elderly individuals
aged ≥65 years with no history of stroke or dementia. Results: The mean age of the participants was
74.43±7.32 years. Of the 554 patients, 106 (19.1%) had WMCs and/or SBI findings on brain CT. The
mean Hcy level was higher in participants with WMCs/SBIs (P=0.001). The WMCs/SBIs group had
a significantly greater number of participants with high Hcy levels than the non-WMCs/SBIs group
(P<0.001). High Hcy levels (≥12.3 μmol/L) was significantly associated with WMCs and SBIs even
after adjusting for age, Korean Mini Mental Status Examination score, education level, and vascular
risk factors such as hypertension, diabetes, hyperlipidemia and smoking status.
Conclusion: The result of our study suggests that regular monitoring of homocysteine level as a
modifiable risk factor may be helpful for predicting the association of cerebrovascular lesions such
as WMCs and SBIs for the prevention of future ischemic stroke and cognitive impairment.
4.Analysis of Femoral cortical Indices in Cementless Femoral Stem
Kwang Suk LEE ; Sang Won PARK ; Seung Beom HAN
The Journal of the Korean Orthopaedic Association 1995;30(3):449-458
Preperative radiologic indices, such as cortical index of Engh, morphological cortical index of Sportono and Romagnoli, canal flare index of Noble, and their relationship to the postoperative canal filling, femoral stem fitness, stability and clinical result at last follow up were analyzed in 111 hips of 96 patients treated with bipolar or total hip arthroplasty at the Department of Chthopedic Surgery, Korea University Hospital, between January 1985 and May 1993. The results obtained were as follows: 1. The cortical index had no correlations with age, metaphyseal filling and clinical result but isthmic filling was proportional to the cortical index. In femoral stem fitness and stability, most cases of press fit and optimal stability were obtained in group 3 and 4 that have thick cortex. 2. The morphological cortical index had no correlation with age, canal filling and clinical results. But it was proportional to the postoperative femoral stem fitness and stability. 3. The canal flare index had no correlation with age. The metaphyseal filling was increased in the stove piped canal group(less than 3.0 canal flare index), but isthmic filling was increased in normal canal group(3.0-4.7 canal flare index). The most cases of press fit and optimal stability were obtained in normal canal group. More satisfactory clinical results were obtained in nomal canal group. Above results suggest that straight type of cementless femoral component could get better press fit fixation, postoperative stability and more satisfactory clinical results in the cases of cortical index larger than 2.0, mophological cortical index larger than 2.7 and canal flare index larger than 4.0 but metaphyseal filling is unsatisfactor.
Arthroplasty
;
Arthroplasty, Replacement, Hip
;
Follow-Up Studies
;
Hip
;
Humans
;
Korea
5.Beckwith-Wiedemann Syndrome with Unusual Sialoadenomegaly.
Hye Seung HAN ; Seung Sook LEE ; Suk Keun LEE ; Je G CHI
Korean Journal of Pathology 1996;30(10):939-942
Beckwith-Wiedemann syndrome is a rare clinical entity characterized by exomphalos, macroglossia, macrosomia, and renal hyperplasia/dysplasia. Although its entity is established, its etiology and obligatory features have not been settled. We report an autopsy case with the unusual involvement of the salivary gland. This infant was born to a 37-year-old mother as a normal full-term spontaneous delivery. At 11 days of age she developed with purulent eye discharge and weak sucking, and died suddenly. At autopsy the baby weighed 2,630 gm and the head circumference was 35 cm. She showed thick and prominent skin folds, bilateral aural fissures, macroglossia, hepatomegaly, cardiomegaly, dysmorphic kidneys, and nesidioblastosis. Both kidneys showed dysplastic tubules and hyperplastic cortical tissue enclosing the medulla. In this case there were characteristic findings in major and minor salivary glands with both acinar and ductal hyperplasia, and hypertrophy of mammary glands. Besides, she had generalized depletion of subcutaneous fat, immature buccal fat, patent ductus arteriosus, hyperlobation of the right lung, two accessory spleens, and hyperplasia of basophils and chromophobes in the pituitary gland. The lungs showed diffuse interstitial pneumonia and multiple fibrin thrombi. There were no adrenal cytomegaly, umbilical hernia and exophthalmos.
Infant
;
Male
;
Female
;
Humans
6.Prevalence and risk factors of cerebral white matter changes and silent infarcts on brain computed tomography scans among community-dwelling healthy adults: The PRESENT project
Hyunyoung Park ; Jaehoon Jo ; JinSung Cheong ; Hyuk Chang ; Hak-Seung Lee ; SangHak Lee ; Seung-Han Suk
Neurology Asia 2014;19(4):351-356
Cerebral white matter changes (WMCs) and silent brain infarcts (SBIs) are common radiologic
findings in neurologically asymptomatic elderly people, but are associated with an increased risk
of subsequent stroke. We investigated the prevalence and risk factors for these cerebral changes on
brain computed tomography (CT) in 480 community-dwelling healthy Korean adults without stroke
or dementia, who were recruited for an early health program. Cerebral WMCs were defined as the
presence of approximately 5 mm wide ill-defined and moderately hypodense lesions, and SBIs were
defined as the presence of >2 mm wide well-defined hypodense lesions. Of the 480 patients, 49 (10.2%)
had cerebral WMCs and SBIs findings on brain CT. The prevalence of WMCs and SBIs increased
with age: the prevalence was 2.4%, 9%, and 32% for subjects in their 50, 60s, and 70s, respectively.
In addition, hypertension, abdominal obesity, increased levels of homocysteine and high sensitivity
C-reactive protein were significantly associated with cerebral WMCs and SBIs. Our study suggests
that regular monitoring of risk factors is required to prevent cerebral WMCs and SBIs and decrease
the incidence of stroke and dementia in healthy individuals.
7.Subclavian vein occlusion and massive upper extremity edema : A complication of subclavian vein catheterization.
Kyung Suk SONG ; Chul MOON ; Dong Cheol HAN ; Seung Duk HWANG ; Hi Bahl LEE
Korean Journal of Nephrology 1993;12(2):172-178
No abstract available.
Catheterization*
;
Catheters*
;
Edema*
;
Subclavian Vein*
;
Upper Extremity*
8.A case of nevus sebaceous associated with sebaceous epithelioma and basal cell epithelioma.
Sung Uk PARK ; Seung Hee LEE ; Han Young WANG ; Ho Suk SUNG
Korean Journal of Dermatology 1992;30(2):225-228
We report a case of nevus sebaceus associated with sebaceous epithelioma and basal cell epithelioma in a 48-year-old male patient. A 2.6 x 2.0cm orange-yellow erosive tumor and 1.5 x 1.0cm, l.0 x 0.8cm dark blue-yellow varigated nodules were intimately associated with a 4 x 3cm sized yellowish verrucous plaque on the parieto-occipital area of the scalp. Biopsy revealed sebaccous epithelioma, basal cell epithelioma and nevus sebaceus, respectively.
Biopsy
;
Carcinoma*
;
Carcinoma, Basal Cell*
;
Humans
;
Male
;
Middle Aged
;
Nevus*
;
Scalp
9.Treatment of Protein-Calorie Malnutrition in Hemodialysis Patient.
Korean Journal of Nephrology 2000;19(5):765-768
No abstract available.
Humans
;
Protein-Energy Malnutrition*
;
Renal Dialysis*
10.Neurologic complications in renal transplant recipients.
Seung Han SUK ; Kyoon HUH ; Yoo Sun KIM ; Ki Il PARK
The Journal of the Korean Society for Transplantation 1993;7(1):187-192
No abstract available.
Transplantation*