2.A case of cystic hygroma managed by bleomycin sclerosing therapy.
Sun O CHANG ; Seung Ha OH ; Ha Won JUNG
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(4):842-846
No abstract available.
Bleomycin*
;
Lymphangioma, Cystic*
3.The result of transseptal transsphenoidal approach to pituitarygland lesion: external rhinoplasty approach.
Yang Gi MIN ; Ha Won JUNG ; Seung Ha OH ; Jong Woo CHUNG ; Won Seok YU ; Hong Jong KIM
Korean Journal of Otolaryngology - Head and Neck Surgery 1992;35(2):309-315
No abstract available.
Rhinoplasty*
4.Pulmonary Alveolar Proteinosis: A Case Report with Diagnostic Features in Bronchoalveolar Lavage Specimen.
Seung Yeon HA ; Hyuni CHO ; Young Ha OH
Korean Journal of Cytopathology 2000;11(2):103-108
Pulmonary alveolar proteinosis(PAP) is a rare disease in which the alveolar spaces are filled with an eosinophilic, PAS-positive material, whereas the interstitial architecture of the lung usually remains unaffected. Although a definitive diagnosis is usually made by an open lung biopsy, bronchoalveolar lavage(BAL) cytology may play a decisive role in the diagnosis and therapy of these patients and may spare a patient a more invasive diagnostic procedure. The author presents a patient in whom BAL cytology specimen contained the characteristic globules of amorphous proteinaceous PAS-positive material accompanied by background of rare macrophages and inflammatory cells. Ultrastructural study using BAL specimen can confirm the diagnosis of PAP.
Biopsy
;
Bronchoalveolar Lavage*
;
Diagnosis
;
Eosinophils
;
Humans
;
Lung
;
Macrophages
;
Pulmonary Alveolar Proteinosis*
;
Rare Diseases
5.The Cytologic Features of Adenoid Cystic Carcinoma of the Uterine Cervix: A Case Report.
Seung Yeon HA ; Hyuni CHO ; Young Ha OH ; Geun Shin LYU
Korean Journal of Cytopathology 1998;9(2):207-212
Adenoid cystic carcinoma of the uterine cervix is a rare tumor accounting for less than 1% of all cervical adenocarcinoma. This tumor is characterized by aggressive biological behavior with frequent local recurrence or metastatic spread, postmenopausal onset, and occasional association with conventional squamous cell carcinoma. The cytologic diagnosis of adenoid cystic carcinoma in the uterine cervix is often difficult because of negative smear due to intact overlying mucosa, cytologic findings mimicking endometrial cells, and masquerade as squamous cell carcinoma. Recently we have experienced a case of adenoid cystic carcinoma arising in the uterine cervix, which was identified on the routine Papanicolaou smear and was histologically confirmed by the consequent biopsy. The smear showed abundant cellularity composed of relatively uniform cells. The tumor cells were arranged in small clusters, acini, naked cells, and loose sheets with abortive cribriform pattern. There were scattered globoid basement membrane-like materials and tumor diathesis. The nuclei were pleomorphic and showed hyperchromatic and coarsely granular choromatin with inconspicuous nucleoli. The punch biopsy of the uterine cervix showed typical histologic findings of adenoid cystic carcinoma characterized by tumor nests composed of hyperchromatic uniform basaloid cells, cribriform pattern, and cylindrical hyaline bodies.
Adenocarcinoma
;
Adenoids*
;
Biopsy
;
Carcinoma, Adenoid Cystic*
;
Carcinoma, Squamous Cell
;
Cervix Uteri*
;
Diagnosis
;
Disease Susceptibility
;
Female
;
Hyalin
;
Mucous Membrane
;
Papanicolaou Test
;
Recurrence
6.Genetic Background of Congenital Hearing Loss.
Journal of Genetic Medicine 2009;6(1):8-24
Understanding the genetic background of hearing loss is important since almost 50% of the cases of profound hearing loss are caused by genetic factors. Until now, more than 150 causative genes have been identified. In this review, classification of genetic hearing loss (syndromic versus non-syndromic, recessive versus dominant, X-linked and mitochondrial), pitfalls in elucidating causative genes, anatomy of the inner ear, introduction of the most common syndromic hearing loss, introduction of the most common non-syndromic hearing loss-causing genes, mitochondrial and multifactorial hearing losses were discussed. Moreover, clinical approaches to the patients with hereditary hearing loss and genetic counseling were also explained briefly. Finally, future directions of the hereditary hearing loss research in Korean population were presented.
Ear, Inner
;
Genes, Mitochondrial
;
Genetic Counseling
;
Hearing
;
Hearing Loss
;
Humans
7.Treatment of sacral pressure sore with transverse lumbosacral back flap.
Jae Sung HA ; Jung Oh SUH ; Jun Yong PARK ; You Seung KIM ; Kun Soo CHUN
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1993;20(3):638-648
No abstract available.
Pressure Ulcer*
8.Clear Cell Islet Cell Tumor of the Pancreas: An Immunohistochemical and Ultrastructural study.
Seung Sam PAIK ; Young Ha OH ; Eun Kyung HONG ; Moon Hyang PARK ; Jung Dal LEE
Korean Journal of Pathology 1997;31(2):162-166
A clear cell islet cell tumor of the pancreas is extremely rare and characterized by extensive clear cell components. Electron microscopic and immunohistochemical findings are essential to prove that the mass with clear cells is an unusual manifestation of an islet cell tumor. Herein, we report a case of clear cell islet cell tumor of a 54-year-old woman with abdominal pain. The tumor was composed of polygonal clear cells arranged in nests, trabeculae, and ribbon pattern with the extensively fibrous stroma. These tumor cells showed strong reactivity for chromogranin and weak reactivity for somatostatin and glucagon. An electron microscope revealed that the important contributing factor of the clear cytoplasmic change was mainly due to an accumulation of lipid droplets, coupled with cytoplasmic swelling in some areas. Some tumor cells showed many endosecretory granules ranging from 111 to 297nm in diameter. In the clinical and immunohistochemical findings these granules were consistent with somatostatin granules in morphology and size.
Abdominal Pain
;
Adenoma, Islet Cell*
;
Cellular Structures
;
Cytoplasm
;
Female
;
Glucagon
;
Humans
;
Islets of Langerhans*
;
Middle Aged
;
Pancreas*
;
Somatostatin
9.Clear Cell Islet Cell Tumor of the Pancreas: An Immunohistochemical and Ultrastructural study.
Seung Sam PAIK ; Young Ha OH ; Eun Kyung HONG ; Moon Hyang PARK ; Jung Dal LEE
Korean Journal of Pathology 1997;31(2):162-166
A clear cell islet cell tumor of the pancreas is extremely rare and characterized by extensive clear cell components. Electron microscopic and immunohistochemical findings are essential to prove that the mass with clear cells is an unusual manifestation of an islet cell tumor. Herein, we report a case of clear cell islet cell tumor of a 54-year-old woman with abdominal pain. The tumor was composed of polygonal clear cells arranged in nests, trabeculae, and ribbon pattern with the extensively fibrous stroma. These tumor cells showed strong reactivity for chromogranin and weak reactivity for somatostatin and glucagon. An electron microscope revealed that the important contributing factor of the clear cytoplasmic change was mainly due to an accumulation of lipid droplets, coupled with cytoplasmic swelling in some areas. Some tumor cells showed many endosecretory granules ranging from 111 to 297nm in diameter. In the clinical and immunohistochemical findings these granules were consistent with somatostatin granules in morphology and size.
Abdominal Pain
;
Adenoma, Islet Cell*
;
Cellular Structures
;
Cytoplasm
;
Female
;
Glucagon
;
Humans
;
Islets of Langerhans*
;
Middle Aged
;
Pancreas*
;
Somatostatin
10.Idiopathic Entero-colic Lymphocytic Phlebitis: A case report.
Seung Sam PAIK ; Young Ha OH ; Eun Kyung HONG ; Jung Dal LEE
Korean Journal of Pathology 1996;30(6):533-538
Localized enterocolic lymphocytic phlebitis is characterized by selective phlebitis involving the small to medium-sized veins and venules, infiltration exclusively by lymphocytes, and no other systemic vasculitis or inflammatory bowel disease. This vasculitis can be a rare cause of intestinal ischemia. We experienced a case of enterocolic lymphocytic phlebitis in a 72-year-old woman, who presented with abdominal pain and distension. The resected colon and terminal ileum showed striking lymphocytic phlebitis affecting the veins and venules of the bowel and mesentery which resulted in ischemic injury of the bowel. This vasculopathy was the only demonstrable cause of ischemia. Arteritis and arteriolitis was not found. There is no clinical or laboratory evidence or a history of extraintestinal vasculitis. The etiology of this clinicopathological entity has not been elucidated. Herein, we report the clinicopathological findings in this patient who presented with ischemic intestinal necrosis caused by localized intestinal lymphocytic phlebitis associated with thrombosis.
Female
;
Humans