1.Prevalence of Penicillinase-Producing Neisseria Gonorrhoeae (PPNG) in Seoul (1995).
Annals of Dermatology 1997;9(4):258-262
BACKGROUND: In recent years gonorrhea has been pandemic and remains one of the most common sexually transmitted diseases(STD) in the world, especially in developing countries. OBJECTIVE & METHOD: For the detection of a more effective therapeutic regimen and to assess the prevalence of penicillinase-producing Neisseria gonorrhoeae (PPNG), we have been studying patients who have visited the VD Clinic of Choong-ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. RESULTS: In 1995, 97 strains of N. gonorrhoeae were isolated, among which 41(42.3%) were PPNG. CONCLUSION: Since the prevalence of PPNG was reported as 21.9% in 1981, the rate fluctuated. However, in 1993, there was an increase up to 74.3%. Thereafter, the prevalence rate decreased to 64.3% in 1994 and 42.3% in 1995. These changes will therefore need continuous observation.
Developing Countries
;
Gonorrhea
;
Humans
;
Methods
;
Neisseria gonorrhoeae*
;
Neisseria*
;
Pandemics
;
Prevalence*
;
Public Health
;
Seoul*
2.Acute cerebral infarction following aconitine ingestion
Hyun Goo Kang ; Seung Jae Lee ; Jin Sung Cheong
Neurology Asia 2017;22(1):65-68
Aconitine is a main component of Aconitum carmichaeli, a Chinese herb known to be effective for
arthritis and neuralgia. Many senior citizens consume the herb as a folk remedy. Aconitine-associated
cardiogenic toxicity has been observed but aconitine-induced cerebrovascular event has not been
reported so far. We report two elderly patients who became unconscious and showed neurological
dysfunction soon after ingesting aconitine for pain control. We speculate that the aconitine induced
cardiac arrhythmia. This resulted in cardiogenic emboli formation with subsequent large territory
cerebral infarction.
Aconitine
3.Clinical study of total vaginal hysterectomy.
Won Myung LEE ; Jong Goo KIM ; Jung Suk PARK ; Woo Jin SOHN ; In Goo KANG ; Yoon Soon LEE ; Seung Bo PARK
Korean Journal of Obstetrics and Gynecology 1993;36(7):2617-2626
No abstract available.
Female
;
Hysterectomy, Vaginal*
4.Chemical burn due to weed killer, Gramoxone@(paraquat dichloride).
Son Won BYEON ; Hye Goo JI ; Seung Kyung HANN ; Won Hyung KANG ; Jinhyong WON
Korean Journal of Dermatology 1991;29(2):218-221
A 62-year-old farmer was admitted to our department because of second degree chemical burns of both buttocks ten days following accidental contact with Gramoxone, a weed killer. He was treated with oral antibiotics and cold compresses and discharged after the burned area were reepithelialized. Laboratory findings were within normal limits for three weeks. Although lung fibrosis, hepatic and renal failure can be caused by repeated absorption of paraquat (Gramoxone) through injuried skin, systemic absorption through normal skin has not been reported. During the four month follow up period there were no systemic problems nor recurrence of skin lesions. We report herein a case of chemical burns induced by Gramoxone, which is probably an occupational dermatosis of farmers handling weed killers.
Absorption
;
Anti-Bacterial Agents
;
Burns
;
Burns, Chemical*
;
Buttocks
;
Fibrosis
;
Follow-Up Studies
;
Humans
;
Lung
;
Middle Aged
;
Paraquat
;
Recurrence
;
Renal Insufficiency
;
Skin
;
Skin Diseases
5.In Vitro Susceptibility of the Herpes Simplex Virus to Acyclovir.
Young Tae KIM ; Seung Goo KANG
Korean Journal of Dermatology 1998;36(4):576-583
BACKGROUND: Acyclovir is a highly effective antiviral agent specifically inhibiting the replication of members of the herpes virus group, in particular the has been used extensively herpes simplex virus types 1 and 2 and the varicella zoster virus. Although acyclovir it has not caused for the treatment or prevention of herpes simplex and varicella zoster virus infections, significant changes in virus sensitivity. OBJECTIVE: The purpose of this study was to evaluate the sensitivity of HSV to acyclovir. METHODS: A total of 80 strains were used 43 strains of non-genital herpes and 37 strains of genital gerpes. These were isolated from 80 patients and were studied to evaluate their sensitivities to acyclovir by the plaque reduction assay. The methods employed to monitor the sensitivity of virus isolates rely on simple dose-response experiments, looking at the effects of increasing concentrations of acyclovir on infected cell culture specimen. The assay is based on quantified plaque counting. The sensitivity of virus strains are then expressed as ID50(concentrations of drug reducing viral cytopathic effect by 50%) and MIC(minimum inhibitory concentration). RESULTS: The results were summarized as follows. 1. The ID50 values of acyclovir for HSV ranged between 0.0625 - 4.0 microgram / ml. For non-genital herpes isolates the mean and median values were 0.459 microgram / ml (SD = 0.624) and 0.250 microgram / ml ; for genital herpes isolates these values were 0.649 microgram / ml (SD = 0.746) and 0.50 microgram / ml . 2. The MIC values of acyclovir for HSV ranged between 0.250 - 32 microgram / ml . For non-genital herpes isolates the mean and median values were 2.605 microgram / ml (SD = 5.270) and 1.00 microgram / ml ; for genital herpes isolates these values were 2.716 microgram / ml (SD = 3.015) and 2.00 microgram / ml . 5. 93.75%(75 strains) of HSV isolates were within the ranges of sensitive HSV strains for acyclovir. CONCLUSION: We are concerned about the resistance of viruses to antiviral drugs, but so far, this has not been documented to be a big problem. With the increasing interest and ability to measure sensitivity of viruses to antiviral drugs we will find out more about viral resistance and its clinical significance.
Acyclovir*
;
Antiviral Agents
;
Cell Culture Techniques
;
Cytopathogenic Effect, Viral
;
Herpes Genitalis
;
Herpes Simplex*
;
Herpesvirus 3, Human
;
Humans
;
Simplexvirus*
6.An experimental comparison of nerve and muscle change with time sequence of neurorrhaphy.
Han Koo LEE ; Sang Hoon LEE ; Kwan Hee LEE ; goo Hyun BAEK ; Seung Baik KANG
The Journal of the Korean Orthopaedic Association 1993;28(6):2281-2289
No abstract available.
7.Vascular risk factors for stroke among urban community dwelling adults in Ansan city, Korea
Hyun Goo Kang ; Seung-Han Suk ; Jin Sung Cheong ; Bum Joon Kim
Neurology Asia 2016;21(4):317-324
Background & Objective: The number of ischemic stroke is increasing steadily. The recent stroke
prevention strategies have targeted risk factors for preventing ischemic stroke. Community-based data
that quantify the prevalence of these risk factors are needed to develop effective stroke prevention
strategies. This study was performed aiming to establish customized prevention strategies by investigating
vascular risk factors of ischemic stroke among the healthy adults in an urban population in Korea.
Methods: The Prevention of Stroke and Dementia (PRESENT) survey collected data associated with
stroke risk factors between 2007 and 2009 in Ansan city, Korea. Of 46,537 people, 2,843 were selected
by random sampling, and final population included 358 men and 422 women over 50 years old. We
checked modifiable risk factors, such as hypertension, diabetes mellitus, smoking, hyperlipidemia,
atrial fibrillation, cardiovascular disease, obesity, and physical inactivity. Results: The mean age of
study subjects was 60.1±8.2 years; 55.5% had hypertension, 18.6% had diabetes mellitus, 17.7% were
current smoker, 44.9% had hyperlipidemia, 1.7% had atrial fibrillation, and 4.5% had cardiovascular
disease. Men had more risk factors for stroke, and higher rates of diabetes mellitus and current
smoking. However, women had higher cholesterol and obesity rates and lower physical activity. The
proportion of individuals with >1 risk factor for stroke increased with age. Hypertension, diabetes
mellitus, and cardiovascular diseases also increased with age, but low-density lipoprotein levels and
current smoking decreased.
Conclusions: This study provides valuable information to develop customized strategic policies for
primary and secondary stroke prevention.
Stroke
8.Surgical treatment of congenital radioulnar synostosis.
Moon Sang CHUNG ; Goo Hyun BAEK ; Jae Hoon AHN ; Seung Baik KANG
The Journal of the Korean Orthopaedic Association 1992;27(4):979-988
No abstract available.
Synostosis*
9.Clinical survey of fetal macrosomia.
In Goo KANG ; Jong Won KIM ; Won Myung LEE ; Jong Koo KIM ; Byung Tae LEE ; Sang Dae KANG ; Seung Bo PARK
Korean Journal of Obstetrics and Gynecology 1991;34(7):941-947
No abstract available.
Fetal Macrosomia*
10.An analysis of 78 cases of tubal ligation rebersals.
Yong Kwan KIM ; Byung Moon KANG ; Yuan Fung SUN ; Young Woo CHANG ; Seung Kwon KOH ; Sook CHO ; Goo Sang KIM
Korean Journal of Obstetrics and Gynecology 1993;36(6):812-817
No abstract available.
Sterilization, Tubal*