1.A Case of Hyperkeratosis of the Nipple and Areola Aggravated During Pregnancy.
Sun Young MOON ; Joo Heung LEE ; Seung Chull LEE
Korean Journal of Dermatology 1994;32(6):1111-1113
We report a case of hyperkeratosis of the nipple and areola occuing in 33 year old woman. She did not have a history of endocriruipathy, horrnonal therapy and other ceatoses, so this case seems to be the nevoid form by Levy-Franckel classification. Interestingly, however the lesion which had developed before marriage suddenly aggr avated during pregnancy. This may be a unique feature which has not been reported elsewhere. Histapathologic findings are compatible with breviously reported eases. There was no response to topical steroid and retinoic acid treatrnent.
Adult
;
Classification
;
Female
;
Humans
;
Marriage
;
Nipples*
;
Pregnancy*
;
Tretinoin
2.Correlation of fetal heart rate patterns in 2nd stage of labor, apgar score of newborns and arterial pH.
Hyun Sam KIM ; Seung Chull LEE ; Chong Ho CHANG ; Young Ho LEE
Korean Journal of Obstetrics and Gynecology 1993;36(7):2674-2681
No abstract available.
Apgar Score*
;
Female
;
Fetal Heart*
;
Heart Rate, Fetal*
;
Humans
;
Hydrogen-Ion Concentration*
;
Infant, Newborn*
;
Pregnancy
3.T lymphocyte subsets, B lymphocyte and NK cell activity in cervical intraspithelial neoplasia and cervical cancer patients.
Seung Chull LEE ; Jong Ho CHANG ; Kwan Soo KIM ; Heong Yul LEE
Korean Journal of Obstetrics and Gynecology 1993;36(7):2667-2673
No abstract available.
Humans
;
Killer Cells, Natural*
;
Lymphocytes*
;
T-Lymphocyte Subsets*
;
Uterine Cervical Neoplasms*
4.Studies on sensitivity and synergism of antifungal agents against candida albicans.
Hae Chull NAH ; Seung Chul LEE ; Inn Ki CHUN ; Young Pio KIM
Korean Journal of Dermatology 1991;29(4):491-499
No abstract available.
Antifungal Agents*
;
Candida albicans*
;
Candida*
5.The Study on the Ultraviolet-B Blocking Effect of Sunscreens in the Epidermal Langerhans Cells of Hairless Mice.
Young Ho WON ; Young Eun YOO ; Seung Chull LEE ; Young Pio KIM ; Inn Ki CHUN
Annals of Dermatology 1995;7(4):288-294
BACKGROUND: Sunscreens have been used widely to prevent the photosensitive skin diseases, skin cancer, and skin aging. However, no sunscreen blocks all kinds of effects caused by ultraviolet light(UVL), and the effect of sunscreens on the impairment of immune function by UVL irradiation is controversial. OBJECTIVE: We try to evaluate the efficiency of sunscreens for blocking the depletion of LC induced by UVB irradiation. METHOD: The ATPase positive LCs were observed in the skin of hairless mice(Hr+/Kud) irradiated by UVB with or without topical application of sunscreens. Two commercially available sunscreens with respective SPF 8 and SPF 30 were applied to the dorsal trunk skin. The mice were irradiated with different increasing doses of UVB at a single time. RESULTS: The ATPase positive LCs in the irradiated dorsal and ear skin were significantly de-creased in densities according to the dosage, and apparently revealed a loss of their dendrites, granulation, and clumping from a UVB dose of more than 60mJ/Cm2. With both sun-screen treatment on the dorsal trunk before irradiation, the densities of LCs on the dorsal skin were significantly higher compared to the un-treated groups at all ranges of UVB doses in spite of a dose dependent decrease in their density. However there was no significant difference on their preventive effect between both sunscreens(SPF 8 and SPF 30) except at high UVB dos-es of more than 240mJ/Cm². CONCLUSION: The LC depletion induced by UVB can be partially protected through the topical application of a sunscreen at a UVB dose dependent fashion. However SPF(sun protective factor) dose not appear to be a good indicator for evaluating sunscreens immunologically.
Adenosine Triphosphatases
;
Animals
;
Dendrites
;
Ear
;
Langerhans Cells*
;
Methods
;
Mice
;
Mice, Hairless*
;
Skin
;
Skin Aging
;
Skin Diseases
;
Skin Neoplasms
;
Sunscreening Agents*
6.Clinical and histopathologic study of malignant melanoma(1980-1990).
Young Ho WON ; Soo Gyoung HUR ; Seung Chull LEE ; Inn Ki CHUNN ; Young Pio KIM
Korean Journal of Dermatology 1991;29(2):193-202
A total of 39 malignant melanoma cases diagnosed at Chonnam National University Hospital for past 10 years from 1980 to April, 1990 were included for the clinicopathologic study. Among the 29 primary cutaneous melanomas, 18 cases(62.1 % ) occurred on the hands and the feet, especially on the heel. The average age of the patients was 54.3 years at the time of diagnosis and the male to female ratio was 1 to 1,4. Acral lentiginous melanoma was the most common (62.1% ) histopathologic type and the invasion level c)f 22 cases(78.4% ) was over 1.50mm by Rreslows thickness.
Diagnosis
;
Female
;
Foot
;
Hand
;
Heel
;
Humans
;
Jeollanam-do
;
Male
;
Melanoma
7.A clinical study of facial bone fractures for the last 5 years.
Sang Chull LEE ; Yeo Gab KIM ; Ryu Dong MOK ; Seung Hwan OH
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1991;17(3):40-45
No abstract available.
Facial Bones*
8.A clinical study of facial bone fractures for the last 5 years.
Sang Chull LEE ; Yeo Gab KIM ; Ryu Dong MOK ; Seung Hwan OH
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1991;17(3):40-45
No abstract available.
Facial Bones*
9.A case of acute lymphocytic leukemia with initial manifestations in the skin.
Jong Soon KIM ; Seung Chull LEE ; Inn Ki CHUN ; Young Pio KIM
Korean Journal of Dermatology 1991;29(1):114-119
The leukemias are a heterogeneous group of neoplasms arising from the malignant transformation of hematopoietic cells. The cutaneous lesions associated with leukemia may be divided into the specific (leukemic infiltration) and nonspecific (leukemids). These may occur separately or in combination with each other. A 28 year old man admitted to the Department of Dermatology in December 1989, for diffuse infiltrated skin lesions of five months duration. In July 1989, he had experienced hyperpigmented diffuse infiltration on the face, which gradually spread to involve the neck and trunk. In November 1989, he felt cervical, submandibular, and inguinal lymph node enlargement. Skin biopsy specimen showed diffuse dermal and subcutaneous infiltration of atypical lymphocytes. Bone marrow biopsy and peripheral blood smear specimen showed changes of acute lymphoblastic leukemia(L). In addition, we studied infiltrated cell.; by immunoperoxidase staining with a pannel of monoclonal antibodies. The results revealed that the atypical cells expressed mainly helper/inducer T cell marker.
Adult
;
Antibodies, Monoclonal
;
Biopsy
;
Bone Marrow
;
Dermatology
;
Humans
;
Leukemia
;
Lymph Nodes
;
Lymphocytes
;
Neck
;
Precursor Cell Lymphoblastic Leukemia-Lymphoma*
;
Skin*
10.A case of sebaceous carcinoma arising from nevus sebaceus of jadassohn.
Soo Gyoung HUR ; Jong Soon KIM ; Seung Chull LEE ; Inn Ki CHUN ; Young Pio KIM
Korean Journal of Dermatology 1991;29(1):104-108
We report a case of sebaceous carcinoma arising from nevus sebaceus of Jadassohn ocurring in a 68-year-old male, who showed a pedunculated cauliflower like tumor mass on verrucoid linear plaque in the fronto-parietal scalp. Histopathologic findings revealed mult,iple irregular tumor lobules composed mainly of foamy cytoplasmic atypical cells suggesting undifferrntiated sebaceous cells. Good result was obtained with wide local excision and primary closure without recurrence for 9 months after surgiral excision.
Aged
;
Brassica
;
Cytoplasm
;
Humans
;
Male
;
Nevus*
;
Nevus, Sebaceous of Jadassohn*
;
Recurrence
;
Scalp