1.Surgical treatment of facial paralysis by using static ancillary procedures.
Seung Jae CHOI ; Seung Ha PARK
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1998;25(8):1531-1539
There is no method of single surgical treatment for facial paralysis, because of its variable condition and variable patient's demand. We usually have been performed the free vascularized gracilis muscle transfer to achieve facial reanimation in cases of the complete facial paralysis. However. most of the patients who visit outpatient room are incomplete facial paralysis. In these cases, we performed the several auxiliary operations for the correction of a drooping eyebrow, paralyzed eyelids, paralysis of the lower lip, and for similar paralytic deformities. To correct a drooping eyebrow, we performed simple eyebrow lifting and upper blepharoplasty. Gold plate implantations and Kuhnt-Szymanowski's method were performed for the lagophthalmos and ectropions individually. To correct a paralyzed lower lip, tensor fascia lata graft was performed with the face lifting. The authors also discuss their operative methods and results of various surgical methods for treating facial paralysis.
Blepharoplasty
;
Congenital Abnormalities
;
Ectropion
;
Eyebrows
;
Eyelids
;
Facial Paralysis*
;
Fascia Lata
;
Humans
;
Lifting
;
Lip
;
Outpatients
;
Paralysis
;
Rhytidoplasty
;
Transplants
2.Role of Renin Angiotensin System in Clitoral avernosum Smooth Muscle.
Seung Choi PARK ; Kyung Woo CHO ; Jong Kwan PARK
Korean Journal of Urology 2000;41(3):387-394
No abstract available.
Muscle, Smooth*
;
Renin*
;
Renin-Angiotensin System*
3.A 20 years, experience with well differentiated thyroid carcinoma in children & teenagers.
Jae Sub PARK ; Seung Hoon CHOI ; Eu Ho HWANG
Journal of the Korean Cancer Association 1991;23(3):640-647
No abstract available.
Adolescent*
;
Child*
;
Humans
;
Thyroid Gland*
;
Thyroid Neoplasms*
4.Binding of B Cell - Derived Autocrine Growth Factor to Hemoglobin.
Jae Seung PARK ; Il Whan CHOI ; Young Mi SHIN
Korean Journal of Immunology 1998;20(1):25-30
Normal human B cells produce autocrine growth factor in response to Staphylococcus aureus Cowan I strain (SAC). However, the functional role and molecular nature of the B cell derived-B cell growth factor (B-BCGF) are largely unknown. We have tried to investigate the nature of B-BCGF using mAb for several years. We report here that B- BCGF is capable of binding to hemoglobin (Hb). The concentrated culture supernatant from tonsillar B cells stimulated with SAC for 24 h was loaded into the fast protein liquid chromatography and ion-exchange chromatography. The peak with BCGF activity was shown to have a M.W. of 16-18 Kda in polyacrylamide gel electrophoresis followed by silver stain. Amino acid sequence of the fraction was found to identical to human hemoglobin (Hb) by more than 85%. However, Hb itself had no BCGF activity. The presence of Hb in culture supernatant was due to the contamination of SRBC during B cell purification. SRSC were completely removed from B cells by percoll-gradient centrifugation and B cells were stimulated with SAC and exogenous Hb was added to the cultures. The Hb fraction from FPLC again showed a BCGF activity. These data strongly suggested that BCGF binds to Hb. We confirmed this in dot blot as well as Western blot. The M.W of Hb-binding BCGF was 20 Kda. This information may provide a rapid progress in research of BCGF.
Amino Acid Sequence
;
B-Lymphocytes
;
Blotting, Western
;
Centrifugation
;
Chromatography, Ion Exchange
;
Chromatography, Liquid
;
Electrophoresis, Polyacrylamide Gel
;
Humans
;
Silver
;
Staphylococcus aureus
5.Photoprotective Effect of Various Sunscreens Against Ultraviolet B - induced Chronic Skin Damage.
Hyun Joo CHOI ; Seung Kyung HANN ; Yoon Kee PARK
Korean Journal of Dermatology 1995;33(1):8-18
BACKGROUND: Chronic exposure to ultraviolet radiation(UVE) nduces photoaging characterized by dry, deeply wrinkled, inelastic, leathery, and irregulaity pigmented skin. UVR also induces solar keratosis and carcinoma, and is a contributing factor in melanoma. Sunscreens are used to prevent solar damage to skin and, if used on a daily lass should significantly reduce the incidence of the chronie photodamaging events. OBJECTIVE: We tried to evaulate the photoaging effects of UVR in the skin and the photoprotective effect of sunscreens. METHOD: We examined the gross and microscopic changes skin of albino hairless Skh : HR-1 mice exposed chronically to ultraviolet B(UVB) and suncreen-treated mice. RESULTS: The skin of the UVB-irradiated mouse shows chear, cteristic signs of photoaging, such as deep wrinkles across the back, and thickened and a hery skin. Histologically, the photoaged skin shows increased epidermal thickness, numeross fibroblasts and inflammatory cell infiltration in the upper dermis, and many enlarged keratering cysts in the lower dermis. By the 20th week, seven of the total of 9 mice(78%) in UVB irradiated mice developed at least one tumor. Histologically, the tumor is a papilloma, but the he are many dyskeratotic cells and loss of polarity in epidermis. Octyl methoxycinnamate or TiO ZnO Talc-treated mic show a significantly decreased wrinkling score, mimmal epidermal hyperplasia, slightly increased dermal cellularity, and lack of proliferation of cysts. The octyl dimethyl PABA-treatd mice shows significantly increased wrinkling score and marked inflammatory infiltration dermis. By the 20th week, only one mouse had developed a tumor in the octyl methoxy irmamate-treated group and no evidence of tumor was seen in the TiO ZnO Talc-treated group. In the octyl dimethyl PABA-treated group, five of 7 mice(71%) developed at least one tumor. CONCLUSION: The skin which is chronically exposed to UVB is subject to photoaging and photocarcinogenesis and regular use of an adequate sunscreen would prevent these photodamaging effects of UVB.
Animals
;
Dermis
;
Epidermis
;
Fibroblasts
;
Hyperplasia
;
Incidence
;
Keratosis
;
Melanoma
;
Mice
;
Mice, Hairless
;
Papilloma
;
Skin*
;
Sunscreening Agents*
6.Dilatation of Severe Corrosive Esophageal Stricture Guided by Right Coronary Artery Catheter.
Sang In LEE ; Seung Hwan SHN ; In Suh PARK ; Heung Jai CHOI
Korean Journal of Gastrointestinal Endoscopy 1991;11(1):77-80
Nonoperative dilatation techniques such as bougination, balloon dilatation, endoscopic laser therapy, and endoscopic electro-coagulation, have been applied to relieve dysphagia due to esophageal strictures, but the most widly used ia peroral dilatation once a guide wire has been passed under direct vision using a fiberoptic endoscope. Some cases of severe and curved esophageal strictures coutd'nt be introduced the conventional steel guide wire. We desecibe a method of cannulation of these difficult strictures guided by torque control angiographic catheter with radiogrphic control. A case of 18 year old man with severe corrosive esophageal stricture ingested HCl was successfully treated with esophageal dilatation with Savary-Gilliard dilator guided by Judkin's right coronary artery catheter.
Adolescent
;
Catheterization
;
Catheters*
;
Constriction, Pathologic
;
Coronary Vessels*
;
Deglutition Disorders
;
Dilatation*
;
Endoscopes
;
Esophageal Stenosis*
;
Humans
;
Laser Therapy
;
Steel
;
Torque
7.A case report of huge spontaneous abdominal wall abscess in diabetic patient
Jae Sub PARK ; Seung Hoo CHOI ; Kyung Rae KIM
Journal of the Korean Diabetes Association 1991;15(1):141-144
No abstract available.
Abdominal Wall
;
Abscess
;
Humans
8.Correlation between Brain Ischemia-Reperfusion Injury and Tumor Necrosis Factor-alpha Following Cardiac Arrest in Rats.
Seung Pil CHOI ; Kyu Nam PARK ; Seung Hyun PARK ; Sang Hyun PARK ; Si Kyoung JEONG ; Se Kyung KIM
Journal of the Korean Society of Emergency Medicine 1999;10(4):531-540
BACKGROUND: Tumor necrosis factor-alpha(TNF-alpha) has been thought to play a major role in neurological injury during global brain ischemia and subsequent reperfusion following resuscitation in cardiac arrest. So, we hypothesized that the elevation in TNF-alpha was dependent upon the duration of the global brain ischemia, and related to delayed neuronal damage. METHODS: Fourteen rats were divided two groups ; 1 minute-cardiac arrest group(n=7) and 3 minute-cardiac arrest group(n=7). we induced cardiac arrest by chest compression and damping of tracheal tube for 1 minute and 3 minutes respectively. And then, resuscitation was initiated. To measure the plasma activity of TNF-alpha, blood samples were drawn before and at the end of cardiac arrest, and 30, 60, 90, and 120 minutes after initiation reperfusion. At 72 hours after resuscitation, the ND(neurologic deficit) score was determined and the histopathologic outcome of hippocampal CA1 neuron was observed by the percent dead hippocampal CA1 neurons. RESULTS: 1. TNF-alpha level during the early reperfusion period(<2h) was significantly increased in 3 min-cardiac arrest group compared with 1 min-cardiac arrest group(p=0.0001). 2. There was a no significant difference of neurologic deficit score between 1 min- and 3 min-cardiac arrest. 3. Percent dead hippocampal neurons were significantly increased in 3 min-cardiac arrest group compared with 1 min-cardiac arrest group(9.1+/-1.2% vs 1.2+/-0.9%, p<0.05). CONCLUSION: The results suggest that longer duration of global brain ischemia causes a more profound increase in plasma TNF-alpha level during the early reperfusion period(<2h) and more delayed neuronal damage than lessor duration of global brain ischemia, and that increase in TNF-alpha level during the early reperfusion period(<2h) is related to delayed neuronal damage.
Animals
;
Brain Ischemia
;
Brain*
;
Heart Arrest*
;
Heart Arrest, Induced
;
Necrosis
;
Neurologic Manifestations
;
Neurons
;
Plasma
;
Rats*
;
Reperfusion
;
Reperfusion Injury*
;
Resuscitation
;
Thorax
;
Tumor Necrosis Factor-alpha*
9.A Case of Polymorphous Light Eruption Confirmed by Phototest.
Young Sik CHOI ; Seung Kyung HANN ; Seung Eun BAEK ; Yoon Kee PARK
Korean Journal of Dermatology 1989;27(5):552-555
Polymorphous light eruption(PMLE) is an idiopathic, scquired syndrome characterized by a delayed abnormal response to light and a varied morphology of recurrent erythema, papules, vesicles or plaques on light-exposed areas of skin. We report herein s 42-year-old male patient who was clinically and histologically compatible with PMLE. To confirm the diagnosis, the phototest was performed by 50,J/crn of UVA, 5MED-UVB and visible light irradiation to the extensor surface of the forearm. Numerous erythematous papules developed at the (JVA-irradiated site. The histopathologic findings of the phototest induced lesion were compatible with PMLE. Therefore, our patient was confirmed as having PMLE with action spectrum in the IJVA range.
Adult
;
Diagnosis
;
Erythema
;
Forearm
;
Humans
;
Light
;
Male
;
Skin
10.Analysis of medical care content in a family physician clinic.
Jong Seung JUNG ; Kyung Mi PARK ; Han Na CHOI ; Seung Uk YUN
Journal of the Korean Academy of Family Medicine 1991;12(12):63-69
No abstract available.
Humans
;
Physicians, Family*