1.Clinical Result of Planned posterior Continuous Curvilinear Capsulorrhexis in Adult Cataract patients: 1 year follow-up.
Chang Hoon RYU ; Hong Bok KIM ; Seung Jeong LIM
Journal of the Korean Ophthalmological Society 2000;41(12):2547-2554
No Abstract Available.
Adult*
;
Capsulorhexis*
;
Cataract*
;
Follow-Up Studies*
;
Humans
2.The Effect of the Toxic Reaction of the Retina by Liposome-encapsulated Tobramycin in Normal Rabbits.
Seung Jeong LIM ; Hong Bok KIM
Journal of the Korean Ophthalmological Society 1992;33(4):357-374
To determine whether liposome-encapsulated tobramycin is less toxic than commercial tobramycin and the threshold dose of liposome-encapsulated tobramycin required to produce toxic reactions when it was injected intravitreally in rabbit, we used liposome-encapsulated tobramycin, tobramycin in PBS, mixture of tobramycin and liposome-encapsulated saline, liposome-encapsulated saline and normal saline respectively. After those were injected, we examined the histologic findings and the functional changes of the retina. The final results are summarized as follows; 1. When tobramycin was injected intravitreally alone, there was no toxic reaction of the retina histologically and functionally with dosage 500 micro gram of commercial tobramycin, but dosage more than 750 micro gram produced toxic reaction. 2. When liposome-encapsulated tobramycin was injected intravitreally, there was toxic reaction of the retina histologically and functionally with dosage 1500 micro gram of tobramycin. 3. When a mixture of tobramycin and liposome-encapsulated saline was injected intravitreally, there was similar toxic reaction as tobramycin used alone with dosage more than 750 micro gram of tobramycin. Liposome-encapsulated saline and normal saline did not produce toxic reaction. The above results indicate that liposome encapsulation markedly reduces the ocular toxicity of tobramycin and that as mnch as dosage 1000 micro gram of liposome-encapsulated tobramycin may be tolerated by the intravitreal route in the rabbit eye. Therefore, the results of this study offer some hope that we may use the method of intravitreal injection of liposome-encapsulated tobramycin safely and effeciently for the treatment of bacterial endophthalmitis in near future.
Endophthalmitis
;
Hope
;
Intravitreal Injections
;
Liposomes
;
Rabbits*
;
Retina*
;
Tobramycin*
3.Clinical Evaluation of AMO Phacoflex SI-30NB in the Aspect of A-constant.
Jee Ho CHANG ; Seung Jung LIM ; Hong Bok KIM
Journal of the Korean Ophthalmological Society 1999;40(4):987-994
We inspected reliability of A-constant of AMO SI-30NB by comparing target diopter and actual postoperative refractive status. Group 1 comprised 191 eyes which were implanted AMO PhacoFlex SI-30NB with corneal incision. Group 2 comprised 45 eyes implanted Pharmacia 812C with scleral incisions. Group 3 comprised 17 eyes implanted AMO OgaciFlex SI-30NB with corneal incision. Refraction was performed on post operative day 1, day 5, day 14, 1 month, and 3 month. It revealed hyperopic shift of 0.31 to 0.40 diopter compared to the target diopters in both Group 1 and Group 3 and no statistical difference was found between two groups(p value>0.05). On the other hand, Group 2 were statistically significant(p value<0.01). We attempted mathematical modelling of this phenomenon and the cause of hyperopylene haptics, structural weakness of haptic-optic junction, and the structure of SI-30NB itself.
Hand
;
Models, Theoretical
4.Budd-Chiari syndrome caused by membranous obstruction of inferior vena cava.
Yong Bok KOH ; Seung Jin YOO ; Yong Pil WANG ; Seok Won LIM
Journal of the Korean Surgical Society 1991;41(4):554-563
No abstract available.
Budd-Chiari Syndrome*
;
Vena Cava, Inferior*
5.Clinical Studies of Aseptic Meningitis.
Seung Ha RHEU ; Soon Bok PARK ; Baek Keun LIM ; Jong Soo KIM
Journal of the Korean Pediatric Society 1984;27(12):1176-1184
No abstract available.
Meningitis, Aseptic*
6.The Potential Acuity Meter to Predict Postoperative Visual Acuity after Cataract Surgery.
Seung Tak OH ; Kang Ho CHOI ; Seung Jung LIM ; Hong Bok KIM
Journal of the Korean Ophthalmological Society 1996;37(4):591-595
The potential acuity meter(PAM) has been reported to be a useful instrument for predicting postoperative visual acuity after cataract extraction surgery. Forty nine eyes were tested with PAM before surgery, and the best postopertive visual acuity was obtained. The PAM accurately predicted the postoperative visual acuity to within three lines in 90.0% of the cases. When the test is in error, the tendency is for the PAM to underestimate the final acuity rather than to overestimate. Especially under undilated pupil, in dense cataracts (<20/200),and,in posterior subcapsular and cortical cataracts, the PAM tends to underestimate further.
Cataract Extraction
;
Cataract*
;
Pupil
;
Visual Acuity*
7.Anatomical Barrier for Anterior and Posterior Capsular Tear Extension.
Seung Jeong LIM ; Jae Bum LEE ; Hong Bok KIM
Journal of the Korean Ophthalmological Society 1995;36(3):411-418
We examined the anatomical barrier for both anterior capsular tear extension and posterior capsular rupture extension which are the most serious intraoperative complications during cataract surgery, using 28 human eyes obtained postmortem. An experimental radial tear, about 1.0 mm in size, was created on the 5.0 mm capsulorhexis margin in the 1st group(7 eyes). Lens nucleus was removed mechanically with hydrodissection and viscoexpression technique. Radial tear extension did not extend over the lens equator in six eyes, and in one eye stopped in front of Wieger's ligament. In the 2nd group(7 eyes), after making zonular rupture around 90 degrees, same procedures were performed. Radial tear extension stopped at the equator in four eyes, and in three eyes stopped in front of Wiegel's ligament. In the 3rd group(7 eyes), we performed capsulorhexis and routine phacoemulsification for lens nucleus and cortex removal. Then we created only a posterior capsule rupture with intact anterior hyaloid membrane and vitreous pressure was increased. Posterior capsular rupture extension stopped in front of Wieger's ligament in all seven eyes. In the 4th group(7 eyes), after creating the rupture of the posterior capsule including anterior hyaloid membrane, intraocular lens was inserted into the empty capsular bag as a perpendicular direction to the axis of the tear. Posterior capsular rupture extension passed Wieger's ligament in only one eye, but did not reach equator or anterior capsule. In this study, we found that zonules, equator portion of the capsular bag and Wieger's ligament act as anatomical barriers for anterior capsular teal extension as well as for posterior capsular rupture extension.
Axis, Cervical Vertebra
;
Capsulorhexis
;
Cataract
;
Humans
;
Intraoperative Complications
;
Lenses, Intraocular
;
Ligaments
;
Membranes
;
Phacoemulsification
;
Rupture
8.A Standard Method of Measuring Tear Film Break-Up Time in Normal Subjects.
Seung Jeong LIM ; Hong Bok KIM ; Shin Jeong KANG ; Sung Min JO
Journal of the Korean Ophthalmological Society 1991;32(2):143-148
The tear film break-up time test is a useful diagnostic test for dry eye syndrome,but it shows a wide range of results in normal subjects according to many factors, especially the methods of measuring it. We studied the factors having some influences on B.U.T. and tried to find out a standard method of measuring B.U.T. in normal subjects. The results were as follows: 1. The subjects were healthy without any ocular disease or symptoms. Total subjects were 200 persons, 400 eyes. 2. The standard method of measuring B.U.T. was as follows: a drop of 0.125% sodium fluorescein was applied into the conjunctival sac and the patient was allowed to blink for at least 1-2 minutes. The tear film was then scanned without holding the lids, using the slit lamp beam, 4-5mm in width. 3. The mean B.U.T. measured by the standard method was 20.35 +/- 6.45 sec in normal subjects. 4. The mean B.U.T. was 18.17 +/- 8.02'sec in the group using fluorescein paper, 9.68 +/- 6.19 sec in the group blinking just 4-5 times,16.54 +/- 8.32 sec in the group measured holding the lids with the fingers, and 18.36 +/- 7.95 sec in the group using a broad beam. 5. There were statistically significant decreases of B.U.T. in the group blinking just 4-5 times and in the group measured holding the lids with the fingers.
Blinking
;
Diagnostic Tests, Routine
;
Fingers
;
Fluorescein
;
Humans
;
Tears*
9.Clinical Analysis of Diabetic Retinopathy According to the Type of Diabetes Mellitus.
Seung Jeong LIM ; Oh Woong KWON ; Hong Bok KIM
Journal of the Korean Ophthalmological Society 1986;27(6):1045-1051
134 cases of Diabetes Mellitus were classified by the National Diabetes Data Group: Type I (Insulin dependent type), Type II (Noninsulin dependent type, II a: Obese type, II b: Konobese type). They were observed by fluorescein angiography and analysed according to variable factors such as sex, age, diabetic maculopathy, visual acuity and duration in each type of Diabetes Mellitus. The results were as follows: 1. Among 134 diabetic patients, incidence of diabetic retinopathy was 48%. Incidence of background retinopathy was 38% and proliferative retinopathy 10%. 2. Type I was more common in younger age, whereas Type II more in over middle age(p<0.05). 3. Diabetic maculopathy was more prevalent in Type II than Type I. 4. Diabetic retinopathy was prevalent in in worsened visual acuity(p<0.005). 5. Incidence of background retinopathy was found to be concerned with duration of Diabetes Mellitus not in Type I, but in Type II(p<0.05). 6. In proliferative retinopathy, duration of Diabetes Mellitus was shorter in Type I but longer in Type II(p<0.05).
Diabetes Mellitus*
;
Diabetic Retinopathy*
;
Fluorescein Angiography
;
Humans
;
Incidence
;
Visual Acuity
10.Clinical Results of AMO Array(R) Multifocal Intraocular Lens.
Jin Hyung KIM ; Hong Bok KIM ; Seung Jeong LIM
Journal of the Korean Ophthalmological Society 2001;42(5):709-712
PURPOSE: To evaluate the clinical results of a AMO Array mutifocal lens. METHOD: we performed a prospective clinical trial of 20 bilateral cataract patients for at least 6 months. RESULT: Mean monocular uncorrected distance acuity(Snellen) was 0.75, which increased to 0.9 with best correction. Mean biocular uncorrected distance acuity was 0.85,which increased to 1.0 with best correction. Mean monocular near acuity was 0.62, which reached 0.88 with best correction. Mean biocular near acuity was 0.71, which reached 1.00 with best correction. Mean contrast sensitivities were within normal range for all spacial frequencies. In glare discomfort, 10 patients had no complaint, 7 patients had no idea, and only 3 patients had some problem. Reading newspaper without glasses was achieved by 28 of 40 eyes(70%) and 15 of 20 patients(75%). CONCLUSION: AMO Array lens can be used as a method of treatment of presbyopia, when combined with correct biometry.
Biometry
;
Cataract
;
Eyeglasses
;
Glare
;
Glass
;
Humans
;
Lenses, Intraocular*
;
Periodicals
;
Presbyopia
;
Prospective Studies
;
Reference Values