1.A Case of A3B.
Young Ae LIM ; Ae Ja PARK ; Seung Hwan CHIN ; Hyae Rim HONG ; Yeung Tak KANG
Korean Journal of Blood Transfusion 1994;5(1):53-56
The results of ABO blood typing in 64-year-old patient with chronic renal and heart failure were positive with anti-B, delayed and weak positive with anti-A in the slide method for the cell typing, mixed-field agglutiniation by light microscopy in the tube method for the cell typing, and also was negative in anti-A, lectin and positive in anti-H, therefore blood typing of this patient was confirmed to A3B.
Blood Grouping and Crossmatching
;
Heart Failure
;
Humans
;
Microscopy
;
Middle Aged
2.An Experimental Study on Tissue Reaction of Various Contrast Agents on Endometrium, Tubal Mucosa, and Peritoneum.
Jae Seung KIM ; Jae Hyung PARK ; Seung Hyup KIM ; Kyung Mo YEON ; Dae Young YOON ; In Ae PARK
Journal of the Korean Radiological Society 1994;31(3):515-522
PURPOSE: To compare the tissue reactions of various water-soluble and oil-based contrast agents on the endometrium, salpingeat mucosa, and peritoneum. MATERIALS AND METHODS: Thirty-three rabbits were used for evaluating the histologic reactions of uterine endometrium, salpinx, and peritoneum. Hysterosalpingography(HSG) was underwent in these rabbits by using Lipiodol, Hexabrix, Rayvist, Ultravist-300, Ultravist-370, and normal saline. Pathotogic results were obtained in each of the six groups from the uterine endometrium, salpingeal mucosa, and peritoneum without knowledge of the contrast agent used and time interval from HSG. RESULTS: Mild inflammations were observed in the endometrium, salpingeal mucosa, and peritoneum during the first week of HSG in all rabbits in which water-soluble contrast agents were used. Although there was no significant difference in the degree of inflammation among the groups using various contrast agents, the group with oil-based contrast agent(Lipiodoi) showed delayed absorption of contrast agent in the peritoneum, frequent intravasation, fat granuloma, peritoneal adhesion, or uterine infarction. CONCLUSION: Our results suggest that water-soluble contrast agents can be used safely for HSG, but the use of oil-based contrast agent is questionable in safety and should be avoided in patients with tubal obstruction, salpingitis, or endometritis.
Absorption
;
Contrast Media*
;
Endometritis
;
Endometrium*
;
Ethiodized Oil
;
Fallopian Tube Diseases
;
Fallopian Tubes
;
Female
;
Granuloma
;
Humans
;
Infarction
;
Inflammation
;
Ioxaglic Acid
;
Mucous Membrane*
;
Peritoneum*
;
Rabbits
;
Salpingitis
3.A Study on the Urinary Incontinence, Lower Urinary Tract Symptoms, Lifestyle and Sexual Matters of Women in an Urban Area.
Seung Ae YANG ; Sun Young PARK ; Soo Jin SHIN
Journal of Korean Academy of Adult Nursing 2004;16(3):398-408
PURPOSE: The purpose of this study was to identify the frequency of urinary incontinence and lower urinary symptoms, to identify lifestyle and sexual matters for UI of adult women in an urban area. METHOD: The sample consisted of 364 educated women from a women's health education program in a public health center. For data collection, the Bristol Female Lower Urinary Tract Symptoms Questionnaire developed by Jackson, et. al.(1996) and the demographic questionnaire were used. For data analysis, SAS 8.2 program was used. RESULT: The results were as follows: 1. the prevalence rate of UI was 73.63%. 45.88% of them were stress incontinence and 27.75% of them were urge incontinence. 2. Remarkable differences were found between the type of UI and LUTS in the case of urgency(x2=42.0585, P<0.001), unexplained incontinence(x2=59.0585, P<0.001), noctural incontinence(x2=18.8080, P<0.001) and catetherization(x2=10.7207, P= 0.004), burning sense(x2=27.7400, P<0.001). 3. Remarkable differences were found between the type of UI and lifestyle matters in the cases as follows fluid intake restriction(x2=31.0532, P=0.008), interference in physical activity(x2= 36.7481, P=0.001), interference in relation with others(x2=22.2729, P=0.034). 4. Remarkable differences were found between the type of UI and sexual matters with difficulty of sexual intercourse(x2=16.1898, P=0.002), and urine leakage during sexual intercourse(x2=17.9752, P=0.001). CONCLUSION: Based on the results, developing and carrying out an adequate UI care and education program is needed.
Adult
;
Burns
;
Data Collection
;
Education
;
Female
;
Humans
;
Life Style*
;
Lower Urinary Tract Symptoms*
;
Prevalence
;
Public Health
;
Statistics as Topic
;
Urinary Incontinence*
;
Urinary Incontinence, Urge
;
Women's Health
;
Surveys and Questionnaires
4.Detection of Cytomegalovirus Infection and IE Gene Variants in Renal Transplant Recipients by Shell Vial Culture and DNA Methods.
Seung Duk HWANG ; Ae Ja PARK ; Hi Bahl LEE
Korean Journal of Nephrology 1998;17(2):323-334
Cytomegalovirus (CMV) is a ubiquitous virus and its infections occur commonly after renal transplantation and immunosuppressive therapy. Early and accurate laboratory diagnosis of CMV infection in renal transplant is necessary but often difficult. To find optimal diagnostic methods for CMV infection, we compared shell vial culture and polymerase chain reaction (PCR) and Southern blot of PCR products. A total of 301 specimens of urine, blood neutrophils, tissues, or body fluids were obtained from 75 renal transplant recipients and were submitted to shell vial culture for CMV as well as DNA PCR using primers for immediate early(IE) gene of CMV. The human fibroblast cell line (MRC-5) was used to culture CMV and were examined with immunofluorescence staining using monoclonal antibody to the early antigen of CMV. The PCR products (274 and 379 bp) were detected by gel electrophoresis and ethidium bromide staining. When PCR products were not clearly visible on electrophoresis, PCR products were analyzed by Southern blot using IE gene probe. Sixty four(85.3%) of 75 renal transplant recipients showed CMV infection as analyzed by PCR and Southern blot as well as shell vial culture. On shell vial culture, CMV were detected in 81 specimens from 30(40%) renal transplant recipients in viremic state. On PCR and Southern blot analysis CMV were detected in 55 and 26 specimens, respectively from 59 patients. The sensitivity of culture and PCR to detect CMV infection were 42.4% and 83.3%, respectively. The results of two studies were concordant in 48%. PCR and Southern blot did not detect CMV in 10 and 5 culture proven CMV positive samples, respectively. Mutant CMV were found in 3 patients which showed 5-10 bp deletion in IE gene. Moreover, DNA sequencing analysis showed 5 mutant strains among 11 strains which appeared same by PCR prodcut. These results suggest that PCR followed by Southern blot may be more sensitive, but less specific than shell vial culture in the diagnosis of CMV disease. PCR followed by Southern blot may not detect mutant CMV. Combined analysis using both shell vial culture and PCR followed by Southern blot may be necessary to diagnose CMV infection in renal transplant recipients.
Blotting, Southern
;
Body Fluids
;
Cell Line
;
Clinical Laboratory Techniques
;
Cytomegalovirus Infections*
;
Cytomegalovirus*
;
Diagnosis
;
DNA*
;
Electrophoresis
;
Ethidium
;
Fibroblasts
;
Fluorescent Antibody Technique
;
Humans
;
Kidney Transplantation
;
Neutrophils
;
Polymerase Chain Reaction
;
Sequence Analysis, DNA
;
Transplantation*
5.Strategies for Adopting and Implementing SNOMED CT in Korea
Hyeoun-Ae PARK ; Seung-Jong YU ; Hyesil JUNG
Healthcare Informatics Research 2021;27(1):3-10
Objectives:
The objective of this study was to introduce the Systematized Nomenclature of Medicine Clinical Terms (SNOMED CT), to describe use cases of SNOMED CT with the barriers and facilitators, and finally, to propose strategies for adopting and implementing SNOMED CT in Korea as a member of SNOMED International.
Methods:
We reviewed a collection of SNOMED CT documents, such as introductory materials, practical guides, technical specifications, and reference materials provided by SNOMED International and the literature on SNOMED CT published by researchers to identify use cases of SNOMED CT with barriers and facilitators. We also surveyed the attendees of SNOMED CT education and training series offered by the Korea Human Resource Development Institute for Health and Welfare to identify perceived barriers to adopting SNOMED CT in Korea.
Results:
We identified the barriers and facilitators to adopt SNOMED CT experienced by international terminology experts and prospective Korean users. They were related to governance and infrastructure, support services for use, education and training programs, use cases, and vendor capability to implement SNOMED CT. Based on these findings, we identified strategies for adopting and implementing SNOMED CT in Korea. They included the establishment of SNOMED CT management infrastructure, the development of SNOMED CT education and training programs for various user groups, the provision of support services for SNOMED CT use, and the development of SNOMED CT use cases.
Conclusions
These strategies for the adoption and implementation of SNOMED CT need to be executed step by step.
6.Fine needle aspiration cytology of salivary gland lesions.
Seung Sook LEE ; In Ae PARK ; Eui Keun HAM ; Sang Kook LEE
Korean Journal of Cytopathology 1993;4(2):111-120
No abstract available.
Biopsy, Fine-Needle*
;
Salivary Glands*
7.Modified Suture Lasso Technique for the Coronoid Process Fractures of the Elbow: Technical Note
Changhyun PARK ; Woojin SHIN ; Seung-Pyo SUH
The Journal of the Korean Orthopaedic Association 2024;59(1):72-76
The coronoid process of the ulna surrounds the distal humerus and plays a vital role in posterior dislocation and posterolateral rotational instability. Elbow stability may not be possible if there is a more than 50% loss. Anteromedial facet fractures can lead to instability, radioulnar synostosis. ulnohumeral arthrosis, severe stiffness. Therefore, surgical fixation is required to ensure adequate elbow stability and decrease the risk of posttraumatic ulnohumeral arthrosis. There are several approaches for the repair of coronoid process fractures.In most cases, the posterior approach was used to make a transosseous tunnel connecting the posterior aspect of the olecranon to fix the fracture site. During surgery, the additional dissection required to repair the coronoid might increase the infection risk, nerve injury, heterotopic ossification, and elbow stiffness. The author performed a modified suture lasso and plate fixation with good outcomes. This paper reports this case with a review of the relevant literature.
8.Diagnostic Value of Urine Latex Test In Bacterial Meningitis.
Seung Min LEE ; Eun Ae PARK ; Seung Joo LEE
Journal of the Korean Pediatric Society 2000;43(1):55-59
PURPOSE: Bacterial meningitis in childhood carries significant mortality and morbidity, so accurate and rapid diagnosis is important. Cerebrospinal fluid (CSF) latex agglutination test has been used for rapid diagnosis of bacterial meningitis. However, urine may be the best specimen for a latex test, because bacterial antigens are concentrated in the urine. The study tried to determine the diagnostic value of urine latex test in bacterial meningitis. METHODS: We evaluated 219 patients who were suspected with bacterial meningitis and examined CSF Gram stain, CSF culture, CSF latex test and urine latex test. And 17 patients with bacterial meningitis were followed up at post-antibiotics 3, 7, 14, 21, 28 days. RESULTS: Sensitivity and specificity of urine latex test in bacterial meningitis were 82.4% and 99.4%. In H. influenzae type b meningitis, the sensitivity and specificity of urine latex test were 100% and 99.4%. The positive rates of urine latex tests after antibiotics treatment persisted significantly longer than the positive rates of CSF culture, smear and latex test. CONCLUSOIN: Urine latex test was as useful as CSF smear and CSF latex test during the early diagnosis of bacterial meningitis. The urine latex test was more valuable than CSF smear, latex, and culture in partially treated bacterial meningitis, because of persistent positivity after antibiotics treatment.
Anti-Bacterial Agents
;
Antigens, Bacterial
;
Cerebrospinal Fluid
;
Diagnosis
;
Early Diagnosis
;
Humans
;
Influenza, Human
;
Latex Fixation Tests
;
Latex*
;
Meningitis
;
Meningitis, Bacterial*
;
Mortality
;
Sensitivity and Specificity
9.The Effect of Low-Dose Dopamine on the Renal Function of Asphyxiated Neonates.
Seung Yeon NAM ; Eun Ae PARK ; Seung Joo LEE
Journal of the Korean Pediatric Society 1998;41(12):1685-1692
PURPOSE: Low-dose dopamine (0.5-3 microgram/kg/min) increases renal blood flow, glomerular filtration rate and natriuresis and has protective and therapeutic effects on oliguric renal failures. Asphyxia is the most common cause of acute renal failure in neonates. But the protective effects of dopamine have never been reported in asphyxiated neonates. So we reported the effects of low-dose dopamine on the renal function of asphyxiated neonates. METHODS: Twenty-seven asphyxiated neonates who were admitted to the neonatal intensive care unit of Ewha Womans University hospital, from September, 1995 to June, 1997, were randomized to dopamine group (N=14, dopamine 0.5-3 microgram/kg/min) and control group (N=13). Serum creatinine (Pcr) and Na (PNa), urine creatinine (Ucr) and Na (UNa), urine output, creatinine clearance rate (Ccr), fractional excretion of Na (FENa) of two groups were compared on postnatal day 1, 3, 5. Incidences of acute renal failure and neonatal complications were also checked. RESULTS: The postnatal changes of Pcr (mg/dL), Ccr (mL/min/1.73m2) and FENa (%), on lst, 3rd & 5th days were not significnatly diffrent between dopamine group and control group. The postnatal changes of UNa (mmol/day) and urine output (ml/kg/hr) in dopamine group on 1st, 3rd & 5th days were significantly higher than those of control group (P<0.05). The incidence of acute renal failure, intraventricular hemorrhage, bronchopulmonary dysplasia, patient ductus arteriosus, sepsis and necrotizing enterocolitis were not significantly different between two groups. CONCLUSION: Low-dose dopamine, which was prophylactically given after birth in asphyxiated neonates, showed natriuretic and diuretic effects without significant increase of glomerular function.
Acute Kidney Injury
;
Asphyxia
;
Bronchopulmonary Dysplasia
;
Creatinine
;
Diuretics
;
Dopamine*
;
Ductus Arteriosus
;
Enterocolitis, Necrotizing
;
Female
;
Glomerular Filtration Rate
;
Hemorrhage
;
Humans
;
Incidence
;
Infant, Newborn*
;
Intensive Care, Neonatal
;
Natriuresis
;
Parturition
;
Polymerase Chain Reaction
;
Renal Circulation
;
Renal Insufficiency
;
Sepsis
10.Estrogen Attenuates the Pressor Response Mediated by the Group III Mechanoreflex.
Seung Ae PARK ; Jong Kyung KIM
Journal of Korean Academy of Nursing 2011;41(2):191-196
PURPOSE: We investigated the effects of group III mechanoreceptors to cardiovascular responses in both pre-menopausal woman and post-menopausal woman during passive ankle dorsiflexion (PAD). METHODS: Twenty healthy volunteers (10 post-menopausal women and 10 pre-menopausal women) were recruited for this study. Stroke volume (SV), heart rate (HR), cardiac output (CO), and total vascular conductances (TVC) were measured continuously throughout the experiment. To stimulate the group III mechanoreceptors, PAD was performed for one minute. RESULTS: The results showed that mean arterial pressure (MAP) mediated by the mechanoreflex activation was significantly increased in both groups. However, this pressor response was significantly higher in post-menopausal women. This reflex significantly increased both SV and CO in pre-menopausal women, while there were no differences in post-menopausal women. There was no difference in HR in either group. The mechanoreflex significantly decreased TVC in post-menopausal woman, while there was no difference in pre-menopausal woman. CONCLUSION: The results indicate that the excessive pressor response mediated by the mechanoreflex occurs due to overactivity of group III mechanorecptors and the mechanism is produced mainly via peripheral vasoconstriction in post-menopausal women.
Aged
;
Blood Pressure
;
Body Mass Index
;
Cardiac Output
;
Estrogens/*metabolism
;
Female
;
Heart Rate
;
Humans
;
Mechanoreceptors
;
Middle Aged
;
Postmenopause
;
Premenopause
;
Reflex, Stretch/*physiology
;
Stroke Volume