and Relevance: Severe necrosis and mild fibrosis were observed in the liver and forelimb skeletal muscles. Based on histological analysis, we diagnosed iron overload myopathy by secondary hemochromatosis. Secondary hemochromatosis with severe muscle atrophy and myositis is very rare, and this is the first report of iron-overload myopathy in a dog.

Purpose: Ultra-processed foods (UPFs) play a significant role in modern diets but are associated with various health risks, including obesity, cardiovascular disease, and diabetes.This study examined the consumption patterns of UPFs among middle-aged adults, older adults, and the oldest older adults in South Korea to identify the key food sources contributing to UPF intake using the Korean NOVA classification system. Methods: Data from the 2016–2019 Korea National Health and Nutrition Examination Survey were analyzed for 13,396 participants aged 40 years and older. Individuals with extreme energy intakes, serious diseases, or incomplete dietary records were excluded. The UPF intake levels were categorized into quartiles (Q1–Q4) based on the proportion of energy derived from UPFs, excluding individuals who did not consume UPFs. Results: In all age groups, the group with a high proportion of UPF consumption tended to have higher energy and macronutrient intake but lower micronutrient intake. The UPFs contributing significantly to energy intake were primarily alcohol and grain-based products.On the other hand, the energy contribution from UPFs based on legumes, milk, and dairy products tended to increase as the level of UPF consumption increased, and this trend was more significant with increasing age. Conclusion This study identified the differences in UPF consumption patterns across age groups and highlighted the importance of selective consumption based on the types of UPFs.

and Relevance: Severe necrosis and mild fibrosis were observed in the liver and forelimb skeletal muscles. Based on histological analysis, we diagnosed iron overload myopathy by secondary hemochromatosis. Secondary hemochromatosis with severe muscle atrophy and myositis is very rare, and this is the first report of iron-overload myopathy in a dog.

Purpose: Ultra-processed foods (UPFs) play a significant role in modern diets but are associated with various health risks, including obesity, cardiovascular disease, and diabetes.This study examined the consumption patterns of UPFs among middle-aged adults, older adults, and the oldest older adults in South Korea to identify the key food sources contributing to UPF intake using the Korean NOVA classification system. Methods: Data from the 2016–2019 Korea National Health and Nutrition Examination Survey were analyzed for 13,396 participants aged 40 years and older. Individuals with extreme energy intakes, serious diseases, or incomplete dietary records were excluded. The UPF intake levels were categorized into quartiles (Q1–Q4) based on the proportion of energy derived from UPFs, excluding individuals who did not consume UPFs. Results: In all age groups, the group with a high proportion of UPF consumption tended to have higher energy and macronutrient intake but lower micronutrient intake. The UPFs contributing significantly to energy intake were primarily alcohol and grain-based products.On the other hand, the energy contribution from UPFs based on legumes, milk, and dairy products tended to increase as the level of UPF consumption increased, and this trend was more significant with increasing age. Conclusion This study identified the differences in UPF consumption patterns across age groups and highlighted the importance of selective consumption based on the types of UPFs.

and Relevance: Severe necrosis and mild fibrosis were observed in the liver and forelimb skeletal muscles. Based on histological analysis, we diagnosed iron overload myopathy by secondary hemochromatosis. Secondary hemochromatosis with severe muscle atrophy and myositis is very rare, and this is the first report of iron-overload myopathy in a dog.

Purpose: Ultra-processed foods (UPFs) play a significant role in modern diets but are associated with various health risks, including obesity, cardiovascular disease, and diabetes.This study examined the consumption patterns of UPFs among middle-aged adults, older adults, and the oldest older adults in South Korea to identify the key food sources contributing to UPF intake using the Korean NOVA classification system. Methods: Data from the 2016–2019 Korea National Health and Nutrition Examination Survey were analyzed for 13,396 participants aged 40 years and older. Individuals with extreme energy intakes, serious diseases, or incomplete dietary records were excluded. The UPF intake levels were categorized into quartiles (Q1–Q4) based on the proportion of energy derived from UPFs, excluding individuals who did not consume UPFs. Results: In all age groups, the group with a high proportion of UPF consumption tended to have higher energy and macronutrient intake but lower micronutrient intake. The UPFs contributing significantly to energy intake were primarily alcohol and grain-based products.On the other hand, the energy contribution from UPFs based on legumes, milk, and dairy products tended to increase as the level of UPF consumption increased, and this trend was more significant with increasing age. Conclusion This study identified the differences in UPF consumption patterns across age groups and highlighted the importance of selective consumption based on the types of UPFs.

and Relevance: Severe necrosis and mild fibrosis were observed in the liver and forelimb skeletal muscles. Based on histological analysis, we diagnosed iron overload myopathy by secondary hemochromatosis. Secondary hemochromatosis with severe muscle atrophy and myositis is very rare, and this is the first report of iron-overload myopathy in a dog.

Objective: We elucidated the effect of monochorionicity on neonatal and long-term neurologic outcomes on an individual basis in triplets. Methods: We retrospectively reviewed the perinatal outcomes and development and growth at 18 to 24 months corrected age (CA) of triplets born alive between 24 and 32 weeks of gestational age (GA) between 2009 and 2021 from the Seoul National University Hospital database. Neurod­evelopmental impairment (NDI) was defined as any delay among the Bayley-III domains (motor and language), cerebral palsy, hearing impairment, or visual loss and was performed at a CA of 18 to 24 months. Results: We included 40 sets of triplets (120 infants), comprising 26, 10, and 4 sets of trichorionic (TC), dichorionic (DC), and monochorionic (MC) triplets, respectively. Ten infants, unaffected by monochorionicity out of 30 DC infants, were included in the non-MC group. Eighty-eight infants were included in the non-MC group, and 32 infants were affected by monochorionicity. In vitro fertilization-embryo transfer was more frequent in the non-MC group (P<0.05), and twin-to-twin transfusion syndrome affected only the MC group (P<0.01). At 24 months of CA, a combined delay of language and cognition in Bayley-III was evident in the MC group (P<0.05). Although NDI did not significantly differ between the 2 groups (P=0.059), the composite outcome of NDI+ postnatal death was significantly different (P<0.05). NDI+ postnatal death correlated with GA, Z-score of birth weight, brain injury, and monochorionicity in the univariate analysis (P<0.05). Multivariate analysis revealed a significant correlation between monochorionicity and NDI+ postnatal death. (P<0.05). Conclusion Monochorionicity is associated with adverse long-term neurodevelopmental out comes.

Objective: We elucidated the effect of monochorionicity on neonatal and long-term neurologic outcomes on an individual basis in triplets. Methods: We retrospectively reviewed the perinatal outcomes and development and growth at 18 to 24 months corrected age (CA) of triplets born alive between 24 and 32 weeks of gestational age (GA) between 2009 and 2021 from the Seoul National University Hospital database. Neurod­evelopmental impairment (NDI) was defined as any delay among the Bayley-III domains (motor and language), cerebral palsy, hearing impairment, or visual loss and was performed at a CA of 18 to 24 months. Results: We included 40 sets of triplets (120 infants), comprising 26, 10, and 4 sets of trichorionic (TC), dichorionic (DC), and monochorionic (MC) triplets, respectively. Ten infants, unaffected by monochorionicity out of 30 DC infants, were included in the non-MC group. Eighty-eight infants were included in the non-MC group, and 32 infants were affected by monochorionicity. In vitro fertilization-embryo transfer was more frequent in the non-MC group (P<0.05), and twin-to-twin transfusion syndrome affected only the MC group (P<0.01). At 24 months of CA, a combined delay of language and cognition in Bayley-III was evident in the MC group (P<0.05). Although NDI did not significantly differ between the 2 groups (P=0.059), the composite outcome of NDI+ postnatal death was significantly different (P<0.05). NDI+ postnatal death correlated with GA, Z-score of birth weight, brain injury, and monochorionicity in the univariate analysis (P<0.05). Multivariate analysis revealed a significant correlation between monochorionicity and NDI+ postnatal death. (P<0.05). Conclusion Monochorionicity is associated with adverse long-term neurodevelopmental out comes.

Objective: We elucidated the effect of monochorionicity on neonatal and long-term neurologic outcomes on an individual basis in triplets. Methods: We retrospectively reviewed the perinatal outcomes and development and growth at 18 to 24 months corrected age (CA) of triplets born alive between 24 and 32 weeks of gestational age (GA) between 2009 and 2021 from the Seoul National University Hospital database. Neurod­evelopmental impairment (NDI) was defined as any delay among the Bayley-III domains (motor and language), cerebral palsy, hearing impairment, or visual loss and was performed at a CA of 18 to 24 months. Results: We included 40 sets of triplets (120 infants), comprising 26, 10, and 4 sets of trichorionic (TC), dichorionic (DC), and monochorionic (MC) triplets, respectively. Ten infants, unaffected by monochorionicity out of 30 DC infants, were included in the non-MC group. Eighty-eight infants were included in the non-MC group, and 32 infants were affected by monochorionicity. In vitro fertilization-embryo transfer was more frequent in the non-MC group (P<0.05), and twin-to-twin transfusion syndrome affected only the MC group (P<0.01). At 24 months of CA, a combined delay of language and cognition in Bayley-III was evident in the MC group (P<0.05). Although NDI did not significantly differ between the 2 groups (P=0.059), the composite outcome of NDI+ postnatal death was significantly different (P<0.05). NDI+ postnatal death correlated with GA, Z-score of birth weight, brain injury, and monochorionicity in the univariate analysis (P<0.05). Multivariate analysis revealed a significant correlation between monochorionicity and NDI+ postnatal death. (P<0.05). Conclusion Monochorionicity is associated with adverse long-term neurodevelopmental out comes.