No abstract available.
Sertoli-Leydig Cell Tumor*

No abstract available.
Sertoli-Leydig Cell Tumor*

No abstract available.
Sertoli-Leydig Cell Tumor*

No abstract available.
Sertoli-Leydig Cell Tumor*

A Sertoli-Leydig cell tumor (SLCT) is an extremely rare type of sex cord stromal tumor of the ovary, which mainly secretes testosterone, thus manifestations of hyperandrogenism commonly appear. This paper shall discuss a case of a postmenopausal woman who presented with pelvic organ prolapse, large left ovarian cyst and mild signs of hyperandrogenism. She underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy, which on microscopic examination of the specimens, revealed a Mature cystic teratoma on the left ovary and an incidental finding of a well-differentiated SLCT, on the grossly normal-looking ovary. This histopathologic diagnosis of SLCT explained the patient’s hyperandrogenic characteristics. Authors likewise discussed the proper management of SLCT, including immunostaining and need for adjuvant chemotherapy.
Sertoli-Leydig Cell Tumor

No abstract available.
Puberty, Precocious* ; Sertoli-Leydig Cell Tumor*

Sertoli-Leydig cell tumor is a rare sex-cord stromal tumor of the ovary and accounts for less than 0.5% of all ovarian tumors. It is among the most fascinating from pathologic and clinical viewpoints in masculinization. We experience an unusual case of a poorly differentiated Sertoli-Leydig cell tumor in 60-year-old woman who showed masculinization and present it with brief review of literature.
Female ; Humans ; Middle Aged ; Ovary* ; Sertoli-Leydig Cell Tumor*

A 26-year-old woman had an ovarian Sertoli-Leydig cell tumor (SLCT) associated with an elevated level of serum alpha-fetoprotein (AFP). The tumor had a heterologous element of intestinal-type mucinous epithelium, retiform and intermediately differentiated tubules of the Sertoli cells, and AFP-producing Leydig cells. AFP was demonstrated within the Leydig cells by an immunohistochemical technique. After surgery, the serum AFP level of the patient fell to the normal range. The present case is the first documented case of AFP producing a SLCT of the ovary reported in Korea.
Adult ; alpha-Fetoproteins* ; Epithelium ; Female ; Humans ; Korea ; Leydig Cells ; Male ; Mucins ; Ovary* ; Reference Values ; Sertoli Cells ; Sertoli-Leydig Cell Tumor*

The Sertoil-Leydig cell tumor (SLCT) is gonadal tumor of sex-cord type, similar to that seen in the various phase of testicular development in the male. It is the most common type of all virilizing ovarian tumors and account for less than 0.5% of all ovarian tumors. A 26-year-old woman had an ovarian SLCT associated with an elevated level of serum AFP. The tumor had a heterologous element of intestinal-type mucinous epithelium, retiform and intermediately differentiated tubules of the Sertoli cell, and AFP-producing Leydig cells. After surgery, the serum AFP level of the patient fell to the normal range. We experienced a case of AFP producing SLCT, so we present it with a brief review of literature.
Adult ; alpha-Fetoproteins* ; Epithelium ; Female ; Gonads ; Humans ; Leydig Cells ; Male ; Mucins ; Ovarian Neoplasms ; Reference Values ; Sertoli-Leydig Cell Tumor*

The Sertoli-Leydig cell tumors are rare ovarian neoplasm representing only 0.1-0.5% of all primary ovarian neoplasms and are composed of sex-cord and stromal elements, that differentiated in a male direction. They are bilatere,l in less than 2% and confined to the ovaries in over 95% of cases. The majority(about two-thirds) of the reported cases are moderately or poorly differentiated Sertoli-Leydig cell tumors. We experienced one case of Sertoli-Leydig cell tumor combined with derrnoid cyst and reported this case with a review of the litenture.
Dermoid Cyst* ; Female ; Humans ; Male ; Ovarian Neoplasms ; Ovary ; Sertoli-Leydig Cell Tumor*