Chronic prostatitis has various symptoms and many problems in management. Recently a lipidosterolic extract of Serenoa Repens, Permixon has been reported to reveal potential antiandrogenic and anti inflammatory activities on prostate. Then we used Permixon on chronic prostatitis and following results were obtained. Permixon is administered orally in dose of 160mg., b.i.d. for 60 days in 31 cases of chronic prostatitis in 1st group, Permixon 160mg, with Cipro-floxacin 500mg, b.i.d. in 35 cases in 2nd group and Placebo 2 tablets, b.i.d. in 30 cases in 3rd group. In 1st group 36 cases(77.4%) were improved, 29 cases(82.8%) in 2nd group and 7 cases (23.3 %) of 3rd group were improved. Permixon is an effective drug in chronic prostatitis and there was no changes in laboratory findings and negligible side effects were noticed
Prostate ; Prostatitis* ; Serenoa* ; Tablets

OBJECTIVETo study the effects of prostadyn sabale capsules on chronic prostatitis (CP).

METHODSOne hundred and twenty-five CP cases were divided into three categories according to National Institutes of Health (NIH) concensus definition and classification of CP:31 of category II. 75 of category IIIA and 19 of category IIIB. All the cases were treated with prostadyn sabale capsules at the dosage of 320 mg twice a day. NIH chronic prostatitis symptom index (NIH-CPSI), routine examination and culture of expressed prostatic secretions (EPS) were prospectively evaluated before and after treatment.

RESULTSThe cure rates of category II, category IIIA and category IIIB were 25.8%, 16.0%, and 21.1% respectively, the general cure rate being 19.2%. The alleviation rate was 63.5% and the total effectivity rate was 82.7%. No side effects were observed.

CONCLUSIONSProstadyn sabale capsules have good effects on CP.

Adult ; Capsules ; Chronic Disease ; Humans ; Male ; Middle Aged ; Phytotherapy ; Prostatitis ; drug therapy ; Serenoa