Purpose: . This study aimed to evaluate the effect of shell thickness on the fracture strength of provisional crowns fabricated by indirect-direct technique. Materials and methods. The study simulated the application of a provisional crown on a maxillary first molar implant abutment. A titanium metal die was milled by replicating a ready-made implant abutment. Using CAD software, shells for provisional crown was designed with varying thicknesses of 0.5 mm, 1.0 mm and 1.5 mm with different internal spaces for relining. These shells were 3D printed using photosensitive liquid resin and relined with PMMA resin to fabricate provisional crown specimens using indirect-direct technique. Ten specimens per each group were prepared. Fracture strength was measured by applying compressive loads vertically to the occlusal center of the specimens at a crosshead speed of 1.0 mm/min using a universal testing machine, and the maximum load value (N) at fracture was recorded. To compare the fracture strength between experimental groups, a one-way ANOVA followed by Tukey’s post hoc test was conducted (α=.05). Results . The fracture strength was observed in the following order: Group 1.5(1504.5 ± 141.30 N), Group 1.0 (1420.2 ± 182.05 N), and Group 0.5 (1083.1 ± 178.90 N). Group 1.5 was not significantly different from group 1.0, but was significantly different from group 0.5, and group 1.0 was also significantly different from group 0.5. Conclusion. The fracture strength of provisional crowns fabricated by the indirect-direct techniques were significantly different depending on the thickness of the shell. The fracture strength of the indirect-direct method was significantly lower when the shell thickness was 0.5 mm compared to 1.0 mm and 1.5mm. This finding indicates that the shell should not be too thin when fabricating provisional crowns using the indirect-direct technique.

Purpose: . This study aimed to evaluate the effect of shell thickness on the fracture strength of provisional crowns fabricated by indirect-direct technique. Materials and methods. The study simulated the application of a provisional crown on a maxillary first molar implant abutment. A titanium metal die was milled by replicating a ready-made implant abutment. Using CAD software, shells for provisional crown was designed with varying thicknesses of 0.5 mm, 1.0 mm and 1.5 mm with different internal spaces for relining. These shells were 3D printed using photosensitive liquid resin and relined with PMMA resin to fabricate provisional crown specimens using indirect-direct technique. Ten specimens per each group were prepared. Fracture strength was measured by applying compressive loads vertically to the occlusal center of the specimens at a crosshead speed of 1.0 mm/min using a universal testing machine, and the maximum load value (N) at fracture was recorded. To compare the fracture strength between experimental groups, a one-way ANOVA followed by Tukey’s post hoc test was conducted (α=.05). Results . The fracture strength was observed in the following order: Group 1.5(1504.5 ± 141.30 N), Group 1.0 (1420.2 ± 182.05 N), and Group 0.5 (1083.1 ± 178.90 N). Group 1.5 was not significantly different from group 1.0, but was significantly different from group 0.5, and group 1.0 was also significantly different from group 0.5. Conclusion. The fracture strength of provisional crowns fabricated by the indirect-direct techniques were significantly different depending on the thickness of the shell. The fracture strength of the indirect-direct method was significantly lower when the shell thickness was 0.5 mm compared to 1.0 mm and 1.5mm. This finding indicates that the shell should not be too thin when fabricating provisional crowns using the indirect-direct technique.

Purpose: . This study aimed to evaluate the effect of shell thickness on the fracture strength of provisional crowns fabricated by indirect-direct technique. Materials and methods. The study simulated the application of a provisional crown on a maxillary first molar implant abutment. A titanium metal die was milled by replicating a ready-made implant abutment. Using CAD software, shells for provisional crown was designed with varying thicknesses of 0.5 mm, 1.0 mm and 1.5 mm with different internal spaces for relining. These shells were 3D printed using photosensitive liquid resin and relined with PMMA resin to fabricate provisional crown specimens using indirect-direct technique. Ten specimens per each group were prepared. Fracture strength was measured by applying compressive loads vertically to the occlusal center of the specimens at a crosshead speed of 1.0 mm/min using a universal testing machine, and the maximum load value (N) at fracture was recorded. To compare the fracture strength between experimental groups, a one-way ANOVA followed by Tukey’s post hoc test was conducted (α=.05). Results . The fracture strength was observed in the following order: Group 1.5(1504.5 ± 141.30 N), Group 1.0 (1420.2 ± 182.05 N), and Group 0.5 (1083.1 ± 178.90 N). Group 1.5 was not significantly different from group 1.0, but was significantly different from group 0.5, and group 1.0 was also significantly different from group 0.5. Conclusion. The fracture strength of provisional crowns fabricated by the indirect-direct techniques were significantly different depending on the thickness of the shell. The fracture strength of the indirect-direct method was significantly lower when the shell thickness was 0.5 mm compared to 1.0 mm and 1.5mm. This finding indicates that the shell should not be too thin when fabricating provisional crowns using the indirect-direct technique.

Purpose: . This study aimed to evaluate the effect of shell thickness on the fracture strength of provisional crowns fabricated by indirect-direct technique. Materials and methods. The study simulated the application of a provisional crown on a maxillary first molar implant abutment. A titanium metal die was milled by replicating a ready-made implant abutment. Using CAD software, shells for provisional crown was designed with varying thicknesses of 0.5 mm, 1.0 mm and 1.5 mm with different internal spaces for relining. These shells were 3D printed using photosensitive liquid resin and relined with PMMA resin to fabricate provisional crown specimens using indirect-direct technique. Ten specimens per each group were prepared. Fracture strength was measured by applying compressive loads vertically to the occlusal center of the specimens at a crosshead speed of 1.0 mm/min using a universal testing machine, and the maximum load value (N) at fracture was recorded. To compare the fracture strength between experimental groups, a one-way ANOVA followed by Tukey’s post hoc test was conducted (α=.05). Results . The fracture strength was observed in the following order: Group 1.5(1504.5 ± 141.30 N), Group 1.0 (1420.2 ± 182.05 N), and Group 0.5 (1083.1 ± 178.90 N). Group 1.5 was not significantly different from group 1.0, but was significantly different from group 0.5, and group 1.0 was also significantly different from group 0.5. Conclusion. The fracture strength of provisional crowns fabricated by the indirect-direct techniques were significantly different depending on the thickness of the shell. The fracture strength of the indirect-direct method was significantly lower when the shell thickness was 0.5 mm compared to 1.0 mm and 1.5mm. This finding indicates that the shell should not be too thin when fabricating provisional crowns using the indirect-direct technique.

Purpose: . This study aimed to evaluate the effect of shell thickness on the fracture strength of provisional crowns fabricated by indirect-direct technique. Materials and methods. The study simulated the application of a provisional crown on a maxillary first molar implant abutment. A titanium metal die was milled by replicating a ready-made implant abutment. Using CAD software, shells for provisional crown was designed with varying thicknesses of 0.5 mm, 1.0 mm and 1.5 mm with different internal spaces for relining. These shells were 3D printed using photosensitive liquid resin and relined with PMMA resin to fabricate provisional crown specimens using indirect-direct technique. Ten specimens per each group were prepared. Fracture strength was measured by applying compressive loads vertically to the occlusal center of the specimens at a crosshead speed of 1.0 mm/min using a universal testing machine, and the maximum load value (N) at fracture was recorded. To compare the fracture strength between experimental groups, a one-way ANOVA followed by Tukey’s post hoc test was conducted (α=.05). Results . The fracture strength was observed in the following order: Group 1.5(1504.5 ± 141.30 N), Group 1.0 (1420.2 ± 182.05 N), and Group 0.5 (1083.1 ± 178.90 N). Group 1.5 was not significantly different from group 1.0, but was significantly different from group 0.5, and group 1.0 was also significantly different from group 0.5. Conclusion. The fracture strength of provisional crowns fabricated by the indirect-direct techniques were significantly different depending on the thickness of the shell. The fracture strength of the indirect-direct method was significantly lower when the shell thickness was 0.5 mm compared to 1.0 mm and 1.5mm. This finding indicates that the shell should not be too thin when fabricating provisional crowns using the indirect-direct technique.

We aimed to investigate associations of dietary diversity (DD) with gut microbial diversity and the development of hen's egg allergy (HEA) in infants. We enrolled 68 infants in a highrisk group and 32 infants in a control group based on a family history of allergic diseases. All infants were followed from birth until 12 months of age. We collected infant feeding data, and DD was defined using 3 measures: the World Health Organization definition of minimum DD, food group diversity, and food allergen diversity. Gut microbiome profiles and expression of cytokines were evaluated by bacterial 16S rRNA sequencing and real-time reverse transcriptase-polymerase chain reaction. High DD scores at 3 and 4 months were associated with a lower risk of developing HEA in the high-risk group, but not in the control group. In the high-risk group, high DD scores at 3, 4, and 5 months of age were associated with an increase in Chao1 index at 6 months. We found that the gene expression of IL-4, IL-5, IL-6, and IL-8 were higher among infants who had lower DD scores compared to those who had higher DD scores in high-risk infants. Additionally, high-risk infants with a higher FAD score at 5 months of age showed a reduced gene expression of IL-13. Increasing DD within 6 months of life may increase gut microbial diversity, and thus reduce the development of HEA in infants with a family history of allergic diseases.

Objective: Adult attention deficit hyperactivity disorder (ADHD) has a heterogeneous clinical presentation with patients showing very frequent emotional problems. In the present study, patients with adult ADHD were subtyped based on their psychopathology using a person-centered approach. Methods: In the present chart review study, detailed findings of psychological evaluation conducted as part of routine care were utilized. A total of 77 subjects with adult ADHD were included in the analysis. Detailed ADHD symptoms, psychiatric comorbid Diagnostic and Statistical Manual of Mental Disorders (DSM) diagnoses, and severity of mood and anxiety symptoms were evaluated in the person-centered analysis. Results: Three clusters were generated using clustering analysis. DSM comorbid conditions did not significantly impact the clustering. Cluster 1 consisted of ADHD combined presentation (ADHD-C) with less mood symptoms, cluster 2 of ADHD predominantly inattentive presentation and cluster 3 of ADHD-C with significant mood symptoms. Patients in cluster 3 had adulthood functional impairment more frequently compared with patients in cluster 1. Patients in cluster 3 showed recurrent thoughts of death and suicidal ideation more frequently compared with patients in cluster 1. Conclusion Further studies are needed to confirm the relationships observed in the present study.

Objective: Adult attention deficit hyperactivity disorder (ADHD) has a heterogeneous clinical presentation with patients showing very frequent emotional problems. In the present study, patients with adult ADHD were subtyped based on their psychopathology using a person-centered approach. Methods: In the present chart review study, detailed findings of psychological evaluation conducted as part of routine care were utilized. A total of 77 subjects with adult ADHD were included in the analysis. Detailed ADHD symptoms, psychiatric comorbid Diagnostic and Statistical Manual of Mental Disorders (DSM) diagnoses, and severity of mood and anxiety symptoms were evaluated in the person-centered analysis. Results: Three clusters were generated using clustering analysis. DSM comorbid conditions did not significantly impact the clustering. Cluster 1 consisted of ADHD combined presentation (ADHD-C) with less mood symptoms, cluster 2 of ADHD predominantly inattentive presentation and cluster 3 of ADHD-C with significant mood symptoms. Patients in cluster 3 had adulthood functional impairment more frequently compared with patients in cluster 1. Patients in cluster 3 showed recurrent thoughts of death and suicidal ideation more frequently compared with patients in cluster 1. Conclusion Further studies are needed to confirm the relationships observed in the present study.