1.Effect of the mutation in the carboxyl-terminal processing site of the hepatitis B virus core antigen on the HBeAg secretion.
Seong Kee KIM ; Jae Woo SHIM ; Hyune Mo RHO
Journal of the Korean Society of Virology 1992;22(2):97-104
No abstract available.
Hepatitis B e Antigens*
;
Hepatitis B virus*
;
Hepatitis B*
;
Hepatitis*
2.Treatment of Chronic Osetomyelitis by Saucerization and Gentamicin
Seong Jong LEE ; Dong Woo JANG ; Taik Seon KIM ; Jae Ik SHIM
The Journal of the Korean Orthopaedic Association 1989;24(2):549-556
Chronic osteomyelitis continue to be a therapeutic challenge. The osteomyelitis also implies chronic ischemia of the diseased bone ; thus systemic antibiotic treatment may not be as effective as we want. In 1972, Klemm developed a new procedure to supplement saucerization in the treatment of chronic osteomyelitis, alternative to irrigation and suction-drainage, i.e., Gentamicin-PMMA Beads. The authors analysed 35cases of the chronic osteomyelitis which were admitted and treated by sauceriztion and Gentamicin-PMMA Beads in Department of Orthopaedic Surgery, Korea Veterans Hospital from Aug. 1984 to Jan. 1988.
Gentamicins
;
Hospitals, Veterans
;
Ischemia
;
Korea
;
Osteomyelitis
;
Polymethyl Methacrylate
3.Vitamin B12 deficiency megaloblastic anemia after total gastrectomy.
Seong Woo LEE ; Kwang Soen SONG ; Sungrul KIM ; Hyun Soo KIM ; Woo Ick JANG ; Young Hak SHIM ; Myung Soo KANG
Korean Journal of Hematology 1992;27(1):105-109
No abstract available.
Anemia*
;
Gastrectomy*
;
Vitamin B 12 Deficiency*
;
Vitamin B 12*
;
Vitamins*
4.Dual Plate Fixation for Displaced Transverse Fracture of the Lower Sacrum
Dong-Hyuk CHOI ; Ji-Hun PARK ; Seong-Woo SHIM ; Yong-Soo CHOI
The Journal of the Korean Orthopaedic Association 2020;55(2):178-182
Isolated fractures of lower sacrum are commonly treated conservatively in most cases because of low energy damage and stable fracture. However, surgical treatment is required in displaced unstable fracture. But the surgical technique is not established and even case reports are not common. We reported a case of displaced transverse fracture of the lower sacrum that was treated with an open reduction and dual plate fixation.
5.Time Course of the Suppression Effect on Transient Evoked Otoacoustic Emissions by Prolonged Contralateral Acoustic Stimulation.
Hyun Woo KANG ; Hyun Joon SHIM ; Seong Jun SONG ; Seong Hee LEE ; Sang Won YOON
Korean Journal of Audiology 2012;16(3):114-119
BACKGROUND AND OBJECTIVES: Although the suppressive effect of the medial efferent acoustic reflex is well known, the time course of this effect over prolonged periods has yet to be fully evaluated. We assessed time-dependent change in the suppression of transient evoked otoacoustic emissions (TEOAEs) by the medial efferent acoustic reflex over a relatively long period. SUBJECTS AND METHODS: We measured TEOAEs in the right ear before contralateral acoustic stimulation (CAS), and then measured serial TEOAEs in the right ear at four intervals during a total of 16 minutes of continuous CAS, followed by three more recordings after termination of CAS. RESULTS: TEOAE amplitudes were reduced with CAS during a certain period (from the immediate period to 10 minutes depending on frequency) and subsequently recovered. TEOAE suppression values in the mean amplitudes for overall frequency were 0.76 dB at the initial recording, 0.35 dB at 5 minutes, 0.44 dB at 10 minutes, and 0.33 dB at 15 minutes during CAS. The initial suppression value was significantly larger than other suppression values of 5, 10, and 15 minutes (p<0.05). In recordings obtained after CAS, TEOAE amplitude exceeded pre-acoustic amplitudes at 1 kHz, 1.5 kHz, and 2 kHz. CONCLUSIONS: The present results show the existence of the medial efferent acoustic reflex and demonstrate the time course that TEOAE suppressions present initially after CAS, showing fatigue over time. Overshooting of TEOAE was observed in recordings at several frequencies after termination of CAS.
Acoustic Stimulation
;
Acoustics
;
Ear
;
Fatigue
;
Reflex, Acoustic
6.Time Course of the Suppression Effect on Transient Evoked Otoacoustic Emissions by Prolonged Contralateral Acoustic Stimulation.
Hyun Woo KANG ; Hyun Joon SHIM ; Seong Jun SONG ; Seong Hee LEE ; Sang Won YOON
Korean Journal of Audiology 2012;16(3):114-119
BACKGROUND AND OBJECTIVES: Although the suppressive effect of the medial efferent acoustic reflex is well known, the time course of this effect over prolonged periods has yet to be fully evaluated. We assessed time-dependent change in the suppression of transient evoked otoacoustic emissions (TEOAEs) by the medial efferent acoustic reflex over a relatively long period. SUBJECTS AND METHODS: We measured TEOAEs in the right ear before contralateral acoustic stimulation (CAS), and then measured serial TEOAEs in the right ear at four intervals during a total of 16 minutes of continuous CAS, followed by three more recordings after termination of CAS. RESULTS: TEOAE amplitudes were reduced with CAS during a certain period (from the immediate period to 10 minutes depending on frequency) and subsequently recovered. TEOAE suppression values in the mean amplitudes for overall frequency were 0.76 dB at the initial recording, 0.35 dB at 5 minutes, 0.44 dB at 10 minutes, and 0.33 dB at 15 minutes during CAS. The initial suppression value was significantly larger than other suppression values of 5, 10, and 15 minutes (p<0.05). In recordings obtained after CAS, TEOAE amplitude exceeded pre-acoustic amplitudes at 1 kHz, 1.5 kHz, and 2 kHz. CONCLUSIONS: The present results show the existence of the medial efferent acoustic reflex and demonstrate the time course that TEOAE suppressions present initially after CAS, showing fatigue over time. Overshooting of TEOAE was observed in recordings at several frequencies after termination of CAS.
Acoustic Stimulation
;
Acoustics
;
Ear
;
Fatigue
;
Reflex, Acoustic
7.The Relationship between ST-T Electrical Alternans on EKG and Ventricular Arrhythmia.
You Hong KIM ; Seong Yun O ; Dal Soo LIM ; Dae Seong HYUN ; Sung Gug CHANG ; Young Hoon YOU ; Young Jo KIM ; Bong Sup SHIM ; Hyun Woo LEE
Korean Circulation Journal 1990;20(3):305-314
In order to observe the development of ventricular arrhythmia during regional myocardial ischemia and reperfusion, especially under the presence or absence of ST-T electrical alternans on epicardial EKG. The proximal left descending coronary artery(LAD) was ligated for 20 minutes and then reperfused suddenly in twenty-three cats. Standard lead EKG(Lead??, chest lead EKG and epicardial lead EKG were recorded simultaneously during the occlusion and reperfusion respectively. During the ligation of LAD, STEA was observed in thirteen cats(56.5%). In occlusion period, the incidence of ventricular tachycardia in STEA positive group was significantly higher than in the negative group(p<0.01) and arrhythmic score was significantly higher(p<0.005) also In the reperfusion period the incidence of vefntricular fibrillation in STEA positive group was significantly higher than in the negative group(p<0.025). But there was the tendency to be higher in arrhythmic score of STEA positive group. There were no differences in heart rate, systolic left ventricular pressure, ST elevation and ST width in both groups. Most forms of ST-T of sinus rhythm before and after development of ventricular premature beat was low form(L). It was concluded that at the presence of STEA on EKG, the incidence of ventricular arrhythmia was more prevalent. So, STEA can be available as a marker of ventricular arrhythmia and prognostic factor.
Animals
;
Arrhythmias, Cardiac*
;
Cardiac Complexes, Premature
;
Cats
;
Electrocardiography*
;
Heart Rate
;
Incidence
;
Ligation
;
Myocardial Ischemia
;
Reperfusion
;
Tachycardia, Ventricular
;
Thorax
;
Ventricular Pressure
8.Hematogenous Candida Pneumonia in Major Burn Patients: Plain Chest Radiograph and Thin-section CT Findings.
Sin Young CHO ; Ell Seong LEE ; Hyo Heon KIM ; Ik Won KANG ; Kil Woo LEE ; Ji Hun KIM ; Hong Kil SUH ; Ya Seong SHIM ; Dae Sun KIM
Journal of the Korean Radiological Society 1995;33(2):227-231
PURPOSE: To describe plain radiographic and thin-section CT findings of hematogenous candida pneumonia in major burn patients. MATERIAL AND METHOD: We reviewed nine cases of hematogenous candida pneumonia in major burn patients who had positive blood culture for candida and findings of pneumonia on plain chest radiograph. On five of nine cases, thin-section CT was done. We evaluated retrospectively nine cases for onset, the pattern, distribution, and size of lesions on plain chest radiograph and thin-section CT. RESULTS: On plain chest radiograph, randomly distributed 2-10mm nodules were seen in six cases(66%) and randomly distributed 10-15mm consolidations in remaining three cases{33% ). Lesion occured in 11th to 75th post-burn day{average, 34th post-burn day). Other findings were cardiomegaly in three cases, atelectasis in three cases, and pulmonary edema in one case. Thin-section CT showed variable shaped subpleural nodules in all five cases. The size of nodules were 1-5mm in two cases(40%) and 5-10mm(60% ) in three cases. Feeding vessel signs were seen in two cases. Other findings were atelectasis in three cases, cardiomegaly in three cases, ground-glass opacity and interlobular septal thickenings by pulmonary edema in two cases. CONCLUSION: Plain chest radiographic findings of hematogenous candida pneumonia in major burn patients are randomly distributed nodules or consolidations of variable size. Thin-section CT findings are variable shaped subpleural nodules less than 1 cm.
Burns*
;
Candida*
;
Cardiomegaly
;
Humans
;
Pneumonia*
;
Pulmonary Atelectasis
;
Pulmonary Edema
;
Radiography, Thoracic*
;
Retrospective Studies
;
Thorax*
9.Clinical Significance of Myocardial Perfusion Imaging Using Oral Dipyridamole Thallium-201 SPECT in Coronary Artery Disease.
Moon Hong DOH ; Seong Kyeong WOO ; Sang Koon SHIM ; Jong Deok LEE ; Jae Goo LEE ; Bong Kwan SEO ; Soon Il JUNG ; Jin Hak CHOI ; Keun Woo LEE
Korean Circulation Journal 1991;21(4):676-685
The clinical utility of thallium-201 SPECT combined dwith pharmacologic vasodilation induced by oral dipyridamole as an alternatiove to intravenous dipyridamole was incestigated in 21 patients who had concomitant coronary arteriography. Tomographic images were assessed visually. Sensitivity & specificity for overall detection of coronary artery disease were 93.7% and 80% respectively. Sensitivity & specificity for identification of indevidual diseased vessels were 84.6% and 87.5% for the left anterior descending artery, 75% and 84.6% for the right coronary artery, 60% and 100% for the left circumflex artery, respecitively. Of the 26 patients unergoing thallium scintigraphy 11 patients(42.3%) had some adverse effects between 20 and 50 minutes after oral dipyrdamole ingestion, including headache(26.9%), chest pain(26.9%), electrocardiographic changes(19.2%), and nausea(11.5%). Intravenous aminophylline was used to resolve these adverse effects in 8 patients & most of the adverse effects were subsided within 10 minutes. There was no ventricular arrhythmias, myocardial infarctions or deaths. In conclusion, oral dipyridamole thallium-201 SPECT is safe and accurate test for the overall detection of coranary artery disease and identification of disease in individual arteries. Furthermore it is useful for determining the necessities of coronary reperfusion and prognstically stratiofying the patients with coronary artery disease.
Aminophylline
;
Angiography
;
Arrhythmias, Cardiac
;
Arteries
;
Coronary Artery Disease*
;
Coronary Vessels*
;
Dipyridamole*
;
Eating
;
Electrocardiography
;
Humans
;
Myocardial Infarction
;
Myocardial Perfusion Imaging*
;
Myocardial Reperfusion
;
Radionuclide Imaging
;
Sensitivity and Specificity
;
Thallium
;
Thorax
;
Tomography, Emission-Computed, Single-Photon*
;
Vasodilation
10.Pulmonary Metastasis of Basal Cell Carcinoma.
Sang Hee SEO ; Woo Haing SHIM ; Dong Hoon SHIN ; Yun Seong KIM ; Hyun Woo SUNG
Annals of Dermatology 2011;23(2):213-216
Although basal cell carcinoma is the most common skin cancer, it rarely metastasizes. Metastatic basal cell carcinoma may, therefore, initially elude diagnosis and management. We describe the case of a patient with a metastatic basal cell carcinoma present in the lungs. The differential diagnosis of suspected metastatic lesions should include metastases from a cutaneous basal cell carcinoma, in addition to those from more commonly metastasizing carcinomas, especially in patients with a history of a large basal cell carcinoma that has involved the head and neck regions, and was refractory to treatment.
Carcinoma, Basal Cell
;
Diagnosis, Differential
;
Head
;
Humans
;
Lung
;
Neck
;
Neoplasm Metastasis
;
Skin Neoplasms