1.Unicompartmental knee arthroplasty.
Sang Cheol SEONG ; Jong Soo JIN ; Kook Hyeong CHO
The Journal of the Korean Orthopaedic Association 1991;26(3):872-876
No abstract available.
Arthroplasty*
;
Knee*
2.Change of the Tibio
Sang Cheol SEONG ; Se Hyun CHO ; Gang Sup YOON
The Journal of the Korean Orthopaedic Association 1984;19(5):784-788
Degenerative arthritis of the knee joint is one of the main causes of disability in middle-aged persons. This paper is planned by the necessity of objective information upon changes of tibio-femoral angle according to weight bearing in patients with degenerative arthritis of the knee joint. The authors studied the tibio-femoral angle in 29 cases of degenerative arthritis of the knee ranging fmm 5th to 6th decades of age, and compared with 27 cases of the control group, in the Dept. of Orthopedic Surgery, S.N.U.H. fmm Mar. 1983 to May 1984. The following observations were obtained: 1. In patients with degenerative arthritis of the knee, changes of the tibio-femoral angle according to weight bearing were +2.2±1.94 in 5th decade, +2.3±2.02 in 6th decade. 2. Compared to control group, the degenerative arthritis group showed a significant varization with weight bearing. 3. It was seemed that the weight bearing radiography is essential in diagnosis and treatment of degenerative arthritis of the knee joint.
Diagnosis
;
Humans
;
Knee
;
Knee Joint
;
Orthopedics
;
Osteoarthritis
;
Radiography
;
Weight-Bearing
3.Lymphangioma in children.
Ma Hae CHO ; Sung Eun JUNG ; Seong Cheol LEE ; Kwi Won PARK ; Woo Ki KIM
Journal of the Korean Surgical Society 1992;43(4):606-611
No abstract available.
Child*
;
Humans
;
Lymphangioma*
4.CT Differentiation of Renal Tumor Invading Parenchyma and Pelvis: Renal Cell Carcinoma vs Transitional Cell Carcinoma.
Cheol Min PARK ; IN Ho CHA ; Kyoo Byung CHUNG ; Chang Hee LEE ; Seong Beum CHO
Journal of the Korean Radiological Society 1994;31(6):1143-1147
PURPOSE: The differentiation between renal cell carcinoma(RCC) and transitional cell carcinoma(TCC) is important due to the different methods of treatment and prognosis. But occasionally it is difficult to draw a distinction between the two diseases when renal parenchyme and renal collecting systems are invaded simultaneously. MATERIAL AND METHOD: We reviewed CT scans of 37 cases of renal cell carcinoma and 12 cases of transitional cell carcinoma which showed involvement of renal parenchyma and renal sinus fat on CT. Retrospective analysis was performed by 3 abdominal radiologists. Check points were renalcontour bulging or reniform shape, location of mass center, intact parenchyme overlying the tumor, cystic change, calcification, LN metastasis, vessel invasion, and perirenal extention. RESULT:There were renal contour bulging due to the tumor mass in 33 out of 37 cases of renal cellcarcinima, wherea and nine of 12 cases of transitional cell carcinoma maintained the reniform appearance. This is significant statiscal difference between the two(p<0.005). Center of all TCCs were located in the renal sinus, and 24 out of 35 cases of RCC were located in the cortex(p<0.005). Thirty-six out of 37 cases of RCC lost the overlying parenchyma, whereas 4 out of 9 cases of well enhanced TCC had intact overlying parenchyma(p<0.005) RCC showed uptic change within the tumor mags in 31 cases which was significanity higher than the 4 cases in TCC(p<0.05). CONCLUSION: CT findings of renal cell carcinoma are contour bulging, peripheral location, obliteration of parenchyma, and cystic change. Findings of transitional cell carcinoma are reniform appearance, central location within the kidney, intact overlying parenchyma, and rare cystic change.
Carcinoma, Renal Cell*
;
Carcinoma, Transitional Cell*
;
Kidney
;
Neoplasm Metastasis
;
Pelvis*
;
Prognosis
;
Retrospective Studies
;
Tomography, X-Ray Computed
6.Exome Chip Analysis of 14,026 Koreans Reveals Known and Newly Discovered Genetic Loci Associated with Type 2 Diabetes Mellitus
Seong Beom CHO ; Jin Hwa JANG ; Myung Guen CHUNG ; Sang Cheol KIM
Diabetes & Metabolism Journal 2021;45(2):231-240
Most loci associated with type 2 diabetes mellitus (T2DM) discovered to date are within noncoding regions of unknown functional significance. By contrast, exonic regions have advantages for biological interpretation. We analyzed the association of exome array data from 14,026 Koreans to identify susceptible exonic loci for T2DM. We used genotype information of 50,543 variants using the Illumina exome array platform. In total, 7 loci were significant with a Bonferroni adjusted We found exonic loci having a susceptibility for T2DM. We found that such genetic information is advantageous for predicting T2DM in a subgroup of obese individuals.
7.Exome Chip Analysis of 14,026 Koreans Reveals Known and Newly Discovered Genetic Loci Associated with Type 2 Diabetes Mellitus
Seong Beom CHO ; Jin Hwa JANG ; Myung Guen CHUNG ; Sang Cheol KIM
Diabetes & Metabolism Journal 2021;45(2):231-240
Most loci associated with type 2 diabetes mellitus (T2DM) discovered to date are within noncoding regions of unknown functional significance. By contrast, exonic regions have advantages for biological interpretation. We analyzed the association of exome array data from 14,026 Koreans to identify susceptible exonic loci for T2DM. We used genotype information of 50,543 variants using the Illumina exome array platform. In total, 7 loci were significant with a Bonferroni adjusted We found exonic loci having a susceptibility for T2DM. We found that such genetic information is advantageous for predicting T2DM in a subgroup of obese individuals.
8.Clinical Application of Arthroscopy in the Patients with Internal Derangement of the Knee
Sang Cheol SEONG ; Choon Ki LEE ; Se Hyun CHO ; Han Koo LEE ; Moon Sik HAHN
The Journal of the Korean Orthopaedic Association 1982;17(6):1164-1170
We applied arthroscopy in the diagnosis of thirty four patients with internal derangement of the knee from March to August, 1982. Its results were compared with clinical diagnosis and arthrographic findings. We also performed arthrofomy in twenty nine patients and the final diagnosis enabled us to evaluate the diagnostic accuracy of each method. The accuracy of clinical diagnosis was 63.4%. Arthrographic findings were correct in 77.8%. The diagnostic accuracy of arthroscopy was 92.3% with one false negative case. Unnecessary operations were avoided in five patients with the assistance of negative findings of arthroscopy. Arthrography and arthroscopy were complementary in the diagnosis of internal derangement of the knee.
Arthrography
;
Arthroscopy
;
Diagnosis
;
Humans
;
Knee
;
Methods
9.Intraosseous Venography for the Early Union Detection of the Femoral Neck Fracture
Key Yong KIM ; Duk Yun CHO ; Young Tae KIM ; Seong Cheol MOON
The Journal of the Korean Orthopaedic Association 1982;17(6):1062-1070
In spite of highly advanced technology in orthopaedic field, management of femoral neck fracture presents difficult problems due to frequent non-union or avascular necrosis of femoral head even with adequate treatments. Intracapsular fracture of the femoral neck heals in the same way as other intra-articular fractures only by endosteal and not by periosteal repair. Avascular necrosis occurred in one-third of displaced fractures with more than a two-year follow-up and is the most serious remaining factor affecting the result. Many attempts have been made to achieve early diagnosis of nonunion and avascular necrosis of the femoral head. Yet, there is still no reliable clinical method of early detection of the union of femoral neck fracture and the viability of the femoral head. For the early detection of union and viability of femoral head, we performed femoral trochanteric intra-osseous venographic technique. Intraosseous venography was performed in 19 cases of femoral neck fractures in the orthopaedic department of National Medical Center during the period from Jan. 1979 to Dec. 1981. The results were as follows: l. 19 patients of femoral neck fracture were performed osteomedullography. Intra-osseous venous flow across the fracture line was seen in 11 cases from 19 patients. 2. Intra-osseous venous flow across the fracture line was seen between the 6th and 12th week following fracture treatment in rigid fixation and adequate reduction. 3. Osteomedullography is considered as very important study for the early diagnosis of the fracture healing and non-union.
Early Diagnosis
;
Femoral Neck Fractures
;
Femur
;
Femur Neck
;
Follow-Up Studies
;
Fracture Healing
;
Head
;
Humans
;
Intra-Articular Fractures
;
Methods
;
Necrosis
;
Phlebography
10.High Tibial Osteotomy
Sang Cheol SEONG ; Se Hyun CHO ; Young Min KIM ; Goo Hyun BAEK
The Journal of the Korean Orthopaedic Association 1984;19(5):881-886
In 1958, Jackson first reported on the use of proximal tibial osteotomy in the treatment of pain due to osteoarthritis of the knee joint. Subsequently, various osteotomy techniques have been reported. The varus deformity of the knee associated with osteoarthritis can be corrected by realigning the joint and thereby shifting the line of weight bearing to the compartment with preserved articular cartilage. This procedure has been found to relieve pain, improve function and arrest the progress of the condition. Twenty five cases of genu varum associated with osteoarthritis were treated by high tibial osteotomy at Dept. of O.S., Seoul National University Hospital, from July 1976 to June 1983. And the following results were obtained. 1. In a review of 25 high tibial osteotomies, excellent and good results were noted in 80% of the knees after average follow-up 2.9 years. 2. Postoperative valgus angles, ranging from 5° to 20°, were averaged to be 10.8°. 3. Though some authors indicate the obesity as one of risk factors, we obtained satisfactory results in 25 knees of obese patients.
Cartilage, Articular
;
Congenital Abnormalities
;
Follow-Up Studies
;
Genu Varum
;
Humans
;
Joints
;
Knee
;
Knee Joint
;
Obesity
;
Osteoarthritis
;
Osteotomy
;
Risk Factors
;
Seoul
;
Weight-Bearing