1.Antimicrobial drug susceptibility of enterobacter and citrobacter islated from clinical specimens.
Sung Duck PAIK ; Won Ki BAEK ; Seong Il SUH ; Jong Wook PARK ; Min Ho SUH
Journal of the Korean Society for Microbiology 1993;28(6):443-451
No abstract available.
Citrobacter*
;
Enterobacter*
2.Characterization of R plasmid and antimicrobial drug resistance of kelbsiella pneumoniae isolated from clinical specimens.
Kyung Ran LEE ; Won Ki BAEK ; Seong Il SUH ; Jong Wook PARK ; Min Ho SUH
Journal of the Korean Society for Microbiology 1991;26(1):25-35
No abstract available.
Drug Resistance, Microbial*
;
Plasmids*
;
Pneumonia*
3.Antimicrobial resistance of escherichia coli isolated from clinical specimens.
Sung Duck PAIK ; Won Ki BAEK ; Seong Il SUH ; Jong Wook PARK ; Min Ho SUH
Journal of the Korean Society for Microbiology 1993;28(4):261-267
No abstract available.
Escherichia coli*
;
Escherichia*
4.Percutaneous Transluminal Angioplasty with Palmaz-Schatz Stent in the Carotid Artery Stenosis.
Sang Sig CHEONG ; Seong Wook PARK ; Seung Jung PARK ; Dae Chul SUH ; Myoung Chong LEE
Korean Circulation Journal 1996;26(4):921-925
Carotid endarterectomy is superior to medical treatment in preventing secondary stroke in patients with symptomatic high grade carotid stenosis. Transluminal angioplasty is a promising procedure as an alternative treatment for these patients. We report two cases of carotid angioplasty with Palmaz-Schatz stent in patients with carotid artery occlusive disease. One patient presented with decreased right visual acuity because of retinal arterial embolism. The angiogram demonstrated a discrete tight stenosis of right internal carotid artery carotid stenting with Palmaz-Schatz coronary stent was performed without any significant complications. The other patient presented with recurrent episodes of cerebral infarction, for which he had undergone left carotid erdarterectomy 3-years ago. The carotid angiogram demonstrated tight stenoses of both internal carotid arteries. Carotid artery stenting was performed at left and right internal carotid arteries without any complications. We suggest that stenting may be an effective and safe therapeutic alternative to surgical treatment in some selected patients with carotid artery occlusive disease.
Angioplasty*
;
Carotid Arteries*
;
Carotid Artery, Internal
;
Carotid Stenosis*
;
Cerebral Infarction
;
Constriction, Pathologic
;
Embolism
;
Endarterectomy, Carotid
;
Humans
;
Retinaldehyde
;
Stents*
;
Stroke
;
Visual Acuity
5.Detection of Chemokine Gene Expression Induced by IL-12/IL-2 in Renca Tumor.
Jong Wook PARK ; Soo Jung YOON ; Seong Il SUH ; In Sook HAN ; Young Kwon KIM
Korean Journal of Immunology 1999;21(1):17-24
In order to evaluate antitumor rnechanisms of interleukin (IL)-12/IL-2 that has been shown significant tumor suppressive activity on established primary and metastatic Renca tumor, we studied chemokine gene expression induced by direct action of IL- 12/IL-2 or cytokine cascade. IL-12/IL-2 induced gene expression of interferon gamma (IFN-r) and granulocyte monocyte-colony stimulating factor (GM-CSF) in splenocytes, and it induced gene expression of monokine induced by IFN-r (Mig), interferon inducible protein 10 (IP- 10), SDF-1, macrophage inflammatory protein (MIP)-1a, MIP-1B, MIP-2, monocyte chemotactic protein (MCP)-1, and Rantes in tumor mass. However IL-12/IL-2 could not induce these chemokines in tumor mass of GKO mice and Renca cell in vitro. IL- 12 also did not increased chemokine gene expression in Renca cell in vitro, but IFN-r induced gene expression of Mig, IP-10, MCP-1 in Renca cell in vitro. In the chemotaxis assay, culture supernatant of Renca cell stimulated with IFN-r increased splenocyte migration in vitro. All these data suggest IL-12/IL-2 can induce IFN-r-chemokine cascade in tumor mass, and Mig, IP-10, MCP-1 produced from tumor cell may play an important role for initial immune cell migration into tumor mass.
Animals
;
Cell Movement
;
Chemokine CCL5
;
Chemokine CXCL10
;
Chemokines
;
Chemotaxis
;
Gene Expression*
;
Granulocytes
;
Interferons
;
Interleukins
;
Macrophages
;
Mice
;
Monocytes
6.Suprapatellar Plica Syndrome Mimicking Soft Tissue Tumor.
Hong Chul LIM ; Sung Woo SUH ; Kyung Wook RHA ; Kee Seong KIM
Journal of the Korean Knee Society 1997;9(2):210-214
The plica is remaining synovial septa in adult life which developed in early fetal life. The suprapatellar plica separates the suprapatellar pouch from the knee joint which sometimes has chnical significance according to its shape, but it has been occasionally overlooked and also pathophysiology of symptomatic plicae may be hard to explain. The authors experienced 7 cases of suprapatellar plica syndrome which mimic soft tissue tumor in 7 patients who had complained of vague pain and ill defined mass around the knee and by arthroscopy found the imperforated suprapatellar plica in which increased hydraulic pressure cavity evokes the clinical symptoms and signs exarnination from 1992 to 1997. We suggest that the suprapatellar plica with complete septum might be clinically significant in patients who are in active life.
Adult
;
Arthroscopy
;
Humans
;
Knee
;
Knee Joint
7.Pelvic Exenteration as the Treatment for Recurrent or Locally Advanced Rectal Cancer.
Seong Kyu SONG ; Yong Keun PARK ; Kwang Wook SUH
Journal of the Korean Society of Coloproctology 2005;21(5):314-319
PURPOSE: The purpose of this study is to evaluate the value of pelvic exenteration (PE) for recurrent or locally advanced rectal cancer. METHODS: This retrospective study analyzed 20 patients who underwent PE for rectal cancer from June 1994 to October 2003 in Ajou University Hospital. The surgical severity, the postoperative complications, and the survival rate were analyed based on the medical records. RESULTS: The mean operation time was 221.5+/-93.0 minutes, the mean blood loss 750.5+/-223.3 cc, and the mean transfusion amount RBC 6.5+/-4.3 units. Operative mortality was 5% (1/20). A bleeding-associated complication was noted in one patient who underwent a reoperation for hemostasis. Other minor complications were small bowel obstruction (n=3), abdominal wound infection (n=5), vesicocutaneous fistula (n=2), delayed healing of the perineal wound (n=10). The overall 5-year survival rate was 52.6% (10 of 19 patients, excluding the operative mortality case). CONCLUSIONS: Our study showed acceptable surgical severity and postoperative complications and a favorable 5-year survival rate (> or =50%) for pelvic exenteration as a treatment for recurrent or locally advanced rectal cancer. With strictly selected patients, PE may be one of the treatment options for recurrent or locally advanced rectal cancer.
Fistula
;
Hemostasis
;
Humans
;
Medical Records
;
Mortality
;
Pelvic Exenteration*
;
Postoperative Complications
;
Rectal Neoplasms*
;
Reoperation
;
Retrospective Studies
;
Survival Rate
;
Wound Infection
;
Wounds and Injuries
8.Direct Cytotoxicity of Interferon-gamma (IFN-gamma) on Renal Cell Carcinoma Cell Line.
Jae Sik YOON ; Soo Jung YOON ; Min Ho SUH ; Seong Il SUH ; Won Ki BAEK ; Young Sun LEE ; Jong Wook PARK ; Sung Joo LEE
Korean Journal of Urology 2000;41(5):587-593
No abstract available.
Carcinoma, Renal Cell*
;
Cell Line*
;
Interferon-gamma*
9.Annual Report of the Central Cancer Registry in Korea-1998 (Based on Registered Data from 124 Hospitals).
Chang In SUH ; Kyung Ae SUH ; Seong Heum PARK ; Hee Jin CHANG ; Jae Wook KO ; Don Hee AHN
Journal of the Korean Cancer Association 2000;32(5):827-834
PURPOSE: Central Cancer Registry Center in Korea conducted a nation-wide hospital-based cancer registry to provide the basic data on cancer statistics. MATERIALS AND METHODS: In 1998, 124 hospitals participated in the cancer registry program. All cancer registry data, submitted from the participating hospitals by diskettes during the year, were reviewed and sorted out by the committee members who were all board-qualified clinical oncologists and pathologists. To avoid duplication, every resident registration numbers were compared by the computer. Cases diagnosed by histologic examination were preferentially chosen. RESULTS: Of 89,226 cases registered, 9,163 (10.3%) duplication cases were excluded. Of the remaining 80,063 cases, 3,195 cases (4.0%) of carcinoma in situ (morphology code /2) were excluded. Finally 76,868 cases were analyzed. Of the analyzed cases, 44,037 (57.3%) were male and 32,831 (42.7%) were female. The leading age groups in the order of relative frequency were 60~64 years of age (15.3%), followed by 55~59 (14.4%). The leading primary cancer sites in the order of relative frequency were stomach (20.9%), followed by liver and intrahepatic bile ducts (12.2%), bronchus and lung (11.9%), colorectum (9.6%), breast (6.1%). In male, the leading primary cancer sites were stomach (24.4%), followed by liver and intrahepatic bile ducts (16.4%), bronchus and lung(16.0%), colorectum(9.2%) and urinary bladder (3.5%). In female, stomach (16.3%) was the most common site, followed by breast (14.1%), uterine cervix (13.0%), colorectum (10.1%) and liver and intrahepatic bile ducts (6.5%). Among the 1,190 cases of childhood malignancies, leukemia (33.4%), CNS tumor (15.7%) and sympathetic nervous system tumor (8.4%) were common. CONCLUSION: We analyzed and reported the registered cancer data from 124 hospitals during 1998.
Bile Ducts, Intrahepatic
;
Breast
;
Bronchi
;
Carcinoma in Situ
;
Cervix Uteri
;
Committee Membership
;
Female
;
Humans
;
Korea
;
Leukemia
;
Liver
;
Lung
;
Male
;
Stomach
;
Sympathetic Nervous System
;
Urinary Bladder
10.Antimicrobial drug resistance and molecular charaterization of R-plasmid of escherichia coli isolated from urine.
Byung Wook SEO ; Sung Choon LEE ; Won Ki BAEK ; Seong Il SUH ; Min Ho SUH
Korean Journal of Urology 1992;33(3):396-403
Ninety nine strains of Escherichia coli isolated from clinical urine specimens in Taegu area were tested for the antimicrobial susceptibility to 20 drugs and studies for molecular and genetic characterization of R-plasmid. All strains were susceptible to amikacin (Ak), moxalactam(Mx), norfloxacin(Nf), ciprofloxacin(Cf) and ofloxacin(Of). One-6.1% of the strains were resistant to tobramycin(To). nalidixic acid(Na), enoxacin(Ex), pefloxacin(Pf) and rifampin(Rf), 17.2-31.3% to gentamicin(Gm), cephalothin(Ct) and cephamandole(Cfm), and 59.6-84.4% to kanamycin (Km), streptomycin(Sm), a.mpicillin(Ap), chloramphenicol(Cm), tetracycline(Tc), sulfisomidine (Su) and trimethoprime(Tp). MIC90 of Ak, Mx, Ex, Nf, Cf, Of and Pf were below the aritimicrobial concentration tested. In multiple drug resistance patterns, resistance to 7 drugs (CmTcSmSuAp TpKm) were most frequently encountered. Except Na and Rf in 66.4 % of resistant strains, most or drug resistance were co-transferred to recipient E.coli RG488 or RG176, indicating that multiple drug resistance was R-plasmid mediated phenomenon. Plasmid profiles for molecular characterization of R-plasmids from B. coli strains were studied through the methods of alkaline SDS lysis and agarose gel electrophoresis. R-plasmids were 40.9-122.3 mega dalton in molecular size. Pst I restriction enzyme digestion patterns of R-plasmid DNAs were examined. R-plasmids with different molecular weights and phenotype markers showed different restriction patterns. pDE9l58 and pDE 9055, which have same molecular weight and phenotype marker except Cfm, showed identical restriction pattern.
Amikacin
;
Daegu
;
Digestion
;
DNA
;
Drug Resistance
;
Drug Resistance, Microbial*
;
Drug Resistance, Multiple
;
Electrophoresis, Agar Gel
;
Escherichia coli*
;
Escherichia*
;
Kanamycin
;
Molecular Weight
;
Phenotype
;
Plasmids
;
Sulfisomidine