Cyclopia is rare congenital craniofacial anomaly, in which the eyes are fused together and located in a single orbit. It is consistently associated with severe holoprosencephaly, which is the failure of cleavage of the prosencephalon with a deficit in the midline facial development. chromosomal study revealed 47, X( ), +13 (Patau syndrome).
Holoprosencephaly ; Orbit ; Prosencephalon ; Trisomy*

Single coronary artery is a rare congenital anomaly occurring in approximately 0.04% of the population. This entity can be diagnosed during life only by coronary angiography. Typical angina does not occur with single coronary artery in the absence of coexisting coronary artery disease or aortic stenosis. Among 874 patients who underwent diagnostic coronary angiography at Asan Medical Center. we have experienced a case of single coronary artery with significant atherosclerotic coronary artery disease which has been managed succesfully coronary angioplasty. We report this case of single coronary artery with a review of literature.
Angioplasty ; Aortic Valve Stenosis ; Chungcheongnam-do ; Coronary Angiography ; Coronary Artery Disease ; Coronary Vessels* ; Humans

No abstract available.
Pregnancy*

Fahr's disease (FD) is a rare neurologic disorder characterized by the symmetric and bilateral intracerebral calcification in a patient. We describe the case of a 65-year-old woman who presented with gait disturbance, abnormal mentality, and visual field defect. The result of a brain computerized tomography showed spontaneous intracranial hemorrhage in the right parieto-occipital area, and also showed the incidence of symmetric and bilateral intracerebral calcification. Moreover, laboratory studies indicated characteristic hypoparathyroidism. This brings us to understand that additionally, one of her sons also presented with similar intracerebral calcification, and was subsequently diagnosed with FD. Thus, her case was consistent with that of a patient experiencing FD. The patient had hypertension, which we now know might have caused the intracerebral hemorrhage. However, this patient's brain lesions were in uncommon locations for spontaneous intracerebral hemorrhage, and the lesions were noted as occurring away from the identified heavily calcified areas. Thus, it seemed that the massive calcification of cerebral vessels in the basal ganglia, the most common site of intracerebral hemorrhage, might have prevented a hypertensive intracerebral hemorrhage. Eventually, an intracerebral hemorrhage occurred in an uncommon location in the patient's brain.
Aged ; Basal Ganglia ; Brain ; Cerebral Hemorrhage ; Female ; Gait ; Humans ; Hypertension ; Hypoparathyroidism ; Incidence ; Intracranial Hemorrhage, Hypertensive ; Intracranial Hemorrhages ; Nervous System Diseases ; Visual Fields

BACKGROUND: Monitoring of "Depth of anesthesia" is an ongoing problem in anaesthesia. In this study, the author has compared the bispectral index (BIS) and Anemon monitor for monitoring depth of anesthesia in propofol or isoflurane anesthesia. METHODS: Anemon-1 and BIS index were obtained from 24 patients (ASA I, II) during general anesthesia with propofol or isoflurane. For patients in the propofol group, anesthesia was induced with fentanyl 100ng followed by propofol 2 mg/Kg. For patients in the isoflurane group, anesthesia was induced with thiopental 5 mg/Kg. The author observed changes of these values at 5 major times: before induction, during induction, after induction, at sKin incision, before extubation, after extubation. RESULTS: The anemon index showed a significant increase during induction (propofol group: 86.9 +/- 26.4, isoflurane group: 106.0 +/- 18.6) and at sKin incision (propofol group: 89.9 +/- 22.7, isoflurane group: 92.0 +/- 23.1), but this did not correlate with the level of consciousness. The BIS index showed a significant decrease in the score after induction (propofol group: 55.0 +/- 9.6, isoflurane group: 61.0 +/- 17.2), but no response to surgical stimuli. CONCLUSIONS: BIS had a good correlation with level of consciousness. The Anemon-1 index was recognized to reflect invasive stimulus. As the BIS and Anemon-1 had no correlation, it was not possible to assume changes of each index from the other. Both the anemon-1 index and BIS are useful to monitor the anesthesia level during surgery.
Anesthesia ; Anesthesia, General ; Consciousness ; Fentanyl ; Humans ; Isoflurane ; Propofol ; Skin ; Thiopental

PURPOSE: To evaluate the recovery of continence after robot-assisted laparoscopic prostatectomy (RALP) and open radical retropubic prostatectomy (RRP). MATERIALS AND METHODS: We identified 258 patients who underwent surgery by a single surgeon to treat localized prostate cancer. The patients were divided into two groups according to operative method. In group 1, 146 consecutive patients underwent RALP, and in group 2, 112 patients underwent RRP. To compare the interval until the return of urinary continence between the two groups, we used the Kaplan-Meier method and the log-rank test and Cox proportional hazard regression analyses. RESULTS: Differences between the two groups were found in mean estimated blood loss (EBL; p<0.001) and the rate of nerve sparing (p=0.004). When continence was defined as the use of 0 to 1 pad per day, 100% of group 1 and 98.2% of group 2 reported continence at 12 months (p=0.189). When continence was defined as no pad use, however, there was a significant difference between the two groups at 12 months: group 1, 95.7%, and group 2, 70.7% (p<0.001). The factors affecting time until no pad use in the univariate analysis with a Cox proportional hazards model were operation method, age, neurovascular bundle saving, membranous urethral length (MUL), EBL, and apical shape. In the multivariate analysis, only operation method, age, and MUL retained significance. CONCLUSIONS: Our study suggests that RALP is an independent factor for the recovery of continence and that RALP has advantages for postoperative continence recovery and the quality of continence compared with RRP.
Humans ; Multivariate Analysis ; Proportional Hazards Models ; Prostatectomy ; Prostatic Neoplasms ; Robotics ; Urinary Incontinence

OBJECTIVE: The purpose of this study was to investigate the effect of thermocycling and type of porcelain restoration on shear bond strength (SBS) and mode of failure of monocrystalline ceramic brackets. METHODS: A total of 60 porcelain discs were made and divided into three equal groups as follows: Ceramco 3, IPS Empress II, Zi-ceram/Vintage ZR. ceramic brackets were bonded to the prepared porcelain surfaces in the same manner. Each group was divided randomly into two subgroups: thermocycled group and non-thermocycled group (control). All samples were tested in shear mode on an universal testing machine. RESULTS: SBS of the non-thermocycled group was clinically acceptable (Ceramco 3: 7.06 +/- 1.76 MPa, IPS Empress II: 7.55 +/- 2.38 MPa, Zi-ceram/Vintage ZR: 7.19 +/- 1.38 MPa). But, SBS of the thermocycled group was significantly reduced (Ceramco 3: 4.88 +/- 1.00 MPa, IPS Empress II: 5.46 +/- 1.35 MPa, Zi-ceram/Vintage ZR: 4.84 +/- 1.01 MPa, p < 0.05). There was no difference between the shear bond strength by type of porcelain restoration. All bonding failure occurred between bracket base and adhesive, except for 2 samples. CONCLUSIONS: The results of this study suggest that the type of porcelain restoration did not affect SBS, but thermocycling weakened SBS. Therefore, the effect of thermocycling should be considered when using ceramic brackets in practice.
Adhesives ; Ceramics ; Collodion ; Dental Porcelain ; Orthodontic Brackets

The current available treatment methods of spasticity are consisted of physical therapies, medications, surgeries, injections of phenol or botulinum, and electrical stimulations. The purposes of this study were to evaluate the effectiveness of surface electrical stimulation in reducing spasticity in the spinal cord injured patients, to find out carry-over effects of electrical stimulation and to find out the factors influencing the effects of the treatment. The subjects were 10 quadriplegics with the cervical cord injuries. The electrical stimulation was applied to the antagonists of major spastic muscles of the knee joints for 2 weeks. The evaluation of spasticity were done by using the modified Ashworth scale, beats of ankle clonus, patellar tendon reflex(latency and amplitude), and relaxation index of patellar knee by pendulum test before and after treatment sessions. The results of the study revealed no statistically significant changes in relaxation index, modified Ashworth scale, ankle clonus and the latency and amplitude of patellar tendon reflex(P<0.05), however there were tendencies of improvement in relaxation index and modified Ashworth scale after the stimulations. We could not find out statistically significant factors influencing the effects of the surface electrical stimulation. Further investigations to assess the mechanism of electrical stimulation and the adquate parameters of electrical stimulation in a larger population of subjects will be needed.
Ankle ; Electric Stimulation* ; Humans ; Knee ; Knee Joint ; Muscle Spasticity* ; Muscles ; Patellar Ligament ; Phenol ; Relaxation ; Spinal Cord Injuries ; Spinal Cord*

Rheumatoid lymphedema (RL) is a rare complication of rheumatoid arthritis (RA). The pathophysiology of RL is not yet fully understood, and the management is also not standardized. As yet, there is low awareness regarding RL and complex decongestive physical therapy (CDPT) among physicians; hence, diagnosis and treatment are delayed. A few studies have reported the positive effects of tumor necrosis factor-α inhibitory drugs on RL. CDPT is still considered the gold standard for the treatment of cancer-related lymphedema, but there are few reports on the effects of CDPT on RL. Therefore, we report two cases of chronic International Society of Lymphology lymphedema stage II RL that exhibited good therapeutic outcomes after CDPT. One of the two patient had taken a tumor necrosis factor-α inhibitory drug, but RL still has progressed. However, CDPT with multilayer bandage showed significant reduction in the pain and edema of the lower extremities.
Arthritis, Rheumatoid ; Bandages ; Compression Bandages ; Diagnosis ; Edema ; Humans ; Lower Extremity ; Lymphedema ; Necrosis

BACKGROUND AND OBJECTIVES: Radial approach was introduced as a route for coronary angiography or interventions. We assessed clinical applicability at a high-volume laboratory and safety. MATERIALS AND METHOD: Procedure-related results were compared between phase I period including learning curve and phase II period in 326 patients, in whom coronary angiography or interventions were performed by radial approach. RESULTS: 1) Success rate was 90% (292/326) in all patients, which significantly increased to 95% (246/259) during phase II compared to 69% (46/67) during phase I. 2) Time from local anesthesia to sheath placement and time for first coronary cannulation were 4.3+/-2.7min, 3.1+/-1.9min, respectively, in all patients, which significantly decreased to 3.8+/-3.6min, 2.7+/-2.4min during phase II compared to 7.0+/-3.2min, 5.7+/-4.7min during phase I. Total examination time was 21.7+/-5.5min in all patients, which significantly decreased to 20.4+/-6.2min during phase II compared to 28.3+/-8.0min during phase I. 3) Overall procedural success rate of coronary interventions was 94% (98/104). Guidewire didn't pass in 5 (5%) patients with chronic total occlusion and stent wasn't delivered in 1 (1%) due to poor guiding backup. 4) During follow-up of 61+/-25 days, weak or absent radial pulse, abnormal reverse Allen test were observed in 13 (5%), 3 (1%), 15 (6%) patients, respectively, but no claudication observed. CONCLUSION: Coronary angiography and interventions by radial approach was safe and performed without more time delay after learning curve.
Anesthesia, Local ; Catheterization ; Coronary Angiography* ; Follow-Up Studies ; Humans ; Learning Curve ; Stents