1.The Effect of Minizide(R) in the Hypertensive Patients.
Jong Seong KIM ; Tae Seong KIM ; Young Sun CHUNG
Korean Circulation Journal 1980;10(1):37-42
The effect of Minizide(R) (prazosine 1mg and polythiazide 0.5mg) was studied in 34 hypertensive patients (female 16 cases, male 18 cases) at the Department of Internal Medicine, Paik Hospital, In-Je Medical College between July, 1979 and August 1980 for 14 months. The patients didn't take the any drugs for one week before the clinical trial with Minizide(R), and thereafter they took minizide 1 tablet 3 times daily for 2 weeks. The blood pressure was checked before and after the trial in the supine and standing position. The results were as followings: 1) The systolic blood pressure before the treatment with Minizide in the supine position was 196+/-24mmHg and in the standing position 188+/-22mmHg. The systolic blood pressure after the treatment with minizide in the supine position was 148+/-16mmHg and in the standing position 139+/-9mmHg. 2) The diastolic blood pressure before the treatment with minizide in the supine position was 118+/-11mmHg, and in the standing position 113+/-10mmHg. The diastolic blood pressure after the treatment with minizide in the supine position was 87+/-6mmHg and in the standing position 84+/-5mmHg. 3) There was no significant orthostatic hypotension after the 34 patients. 4) There was no changes of laboratory findings after the treatment. 5) 3 of 34 hypertensive patients after the treatment complained of headache, 3 palpitation, 2 edema, 2 drowsiness, and 1 fatigability and 1 patient complained of weakness.
Blood Pressure
;
Edema
;
Headache
;
Humans
;
Hypotension, Orthostatic
;
Internal Medicine
;
Male
;
Polythiazide
;
Sleep Stages
;
Supine Position
2.A Case of Acquired Ichthyosis Developed During Cholesterol-lowering Treatment.
Seong Jai JEONG ; Young Tae KIM
Korean Journal of Dermatology 1997;35(3):546-550
A 42-year-old woman presented with ichthyosiform eruptions on her trunk and buttock which developed 20 days prior to consulatation. She had taken the cholesterol-lowering drug(lovastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A (HMG CoA) reductase inhibitor) for 4 months. After stopping the drug, the skin lesions gradually improved and after two months most of the lesions had disappeared. After 3 months of follow up the skin lesions could not be seen any more. Acquired ichthyosis in our patient could be an untoward effect of HMG CoA reductase inhibitor by disturbing the skin lipid metabolism.
Adult
;
Buttocks
;
Female
;
Follow-Up Studies
;
Humans
;
Hydroxymethylglutaryl CoA Reductases
;
Ichthyosis*
;
Lipid Metabolism
;
Lovastatin
;
Oxidoreductases
;
Skin
3.A Case of 5 alpha-reductase Deficiency in Infancy.
Journal of Korean Society of Pediatric Endocrinology 1998;3(1):96-101
5 alpha-reductase deficiency resulting in male pseudohermaphroditism is a rare disease characterized by clitoral-like phallus, bifid scrotum, urogenital sinus, testis cited in labioscrotal folds. Evaluation of plasma T/DHT ratios in infancy, particularly after hCG stimulation of the testes and elevated urinary tetrahydrocortisol (THF) to 5 alpha-tetrahydrocortisol(5 alpha-THF) ratios provide a valuable dianostic test for 5 alpha-reductase deficiency. We report one case of 5 alpha-reductase deficiency who were presented with ambiguous genitalia and elevated T/DHT ratio before and after hCG stimulation.
46, XY Disorders of Sex Development
;
Cholestenone 5 alpha-Reductase*
;
Disorders of Sex Development
;
Plasma
;
Rare Diseases
;
Scrotum
;
Testis
;
Tetrahydrocortisol
4.2010 Conversion of the Journal of Korean Medical Science to Monthly Publication as an Open Access Journal.
Sung Tae HONG ; Seong Deok KIM
Journal of Korean Medical Science 2010;25(1):1-1
No abstract available.
5.Nesidioblastosis in Neonate with Persistent Hyperinsulinemic Hypoglycemia.
Il Tae WHANG ; Ho Seong KIM ; Ho Seong HAN
Journal of Korean Society of Pediatric Endocrinology 1998;3(2):231-236
Nesidioblastosis, also known as persistent hyperinsulinemic hypoglycemia of infancy(PHHI) or familial hyperinsulinsm, is the most common cause of recurrent severe hypoglycemia in infancy. It is an autosomal recessive disorder characterized by irregular insulin secretion leading to inappropriately raised plasma insulin concentration compared to blood glucose levels. Recently, mutations in the sulfonylurea receptor(SUR) have been described in association with PHHI. The mainstay of medical treatment is glucose infusion and diazoxide or long acting somatostatin. If medical treatment fails in preventing hypoglycemia, near total pancreatectomy is recommended. We report one case of nesidioblastosis cured by near total pancreatectomy with brief review of literatures.
Blood Glucose
;
Congenital Hyperinsulinism*
;
Diazoxide
;
Glucose
;
Humans
;
Hypoglycemia
;
Infant, Newborn*
;
Insulin
;
Nesidioblastosis*
;
Pancreatectomy
;
Plasma
;
Somatostatin
6.Giant Osteoma of the Anterior Cranial Fossa: Case Report .
Ki Seong EOM ; Tae Young KIM ; Jong Moon KIM
Journal of Korean Neurosurgical Society 2002;32(1):59-62
Osteoma is the most common benign tumor of the cranium, and the frontal sinus is its most frequent location in the cranium. A 39-year-old woman presented with left exophthalmos was found to have orbital and intracranial extension of a giant osteoma involving anterior cranial fossa. The etiology, presenting features, diagnosis and treatment of this tumor are reviewed.
Adult
;
Cranial Fossa, Anterior*
;
Diagnosis
;
Exophthalmos
;
Female
;
Frontal Sinus
;
Humans
;
Orbit
;
Osteoma*
;
Skull
7.Superiority of modified university of Wisconsin solution in the prolonged preservation of isolated rat heart.
Jae Seong LEE ; Song Myung KIM ; Kyu Tae KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 1993;26(6):427-440
No abstract available.
Animals
;
Heart*
;
Rats*
;
Wisconsin*
8.A Comparative Study of Arrhythmogenic Doses of Epinephrine during Sevoflurane or Halothane Anesthesia in the Dogs.
Byeong Seong KANG ; Seok Hoon YOON ; Tae Seong KIM ; Hyun Soo KIM ; Kwang Min KIM
Korean Journal of Anesthesiology 1997;33(1):1-5
BACKGROUND: Epinephrine used in surgery to provide hemostasis may elicit ventricular arrhythmias. A desirable anesthetic would not sensitize the myocardium to exogenously administered epinephrine. So the effect of sevoflurane, which was introduced to clinical anesthesia recently, on cardiac arrhythmias induced by the infusion of epinephrine was compared with those of halothane which was already known to epinephrine-induced arrhythmia in the 14 mongrel dogs. METHODS: The authors compared the arrhythmogenicity (three or more premature ventricular contractions, PVCs)of intravenously administered epinephrine in 14 mongrel dogs who were randomly assigned to receive sevoflurane (1.7 vol%) or halothane (0.75 vol%) anesthesia equipotently. The arrhythmogenic doses of epinephrine determined in this comparative study were expressed by both infusion rates of epinephrine during sevoflurane and halothane anesthesia. RESULTS: The mean values of the arrythmogenic infusion rates of epinephrine were 27.1 7.6 g/kg for sevoflurane and 2.7 0.8 g/kg for halothane. CONCLUSIONS: We concluded that the arrythmogenic doses of epinephrine during sevoflurane were significantly higher than those during halothane anesthesia.
Anesthesia*
;
Animals
;
Arrhythmias, Cardiac
;
Dogs*
;
Epinephrine*
;
Halothane*
;
Hemostasis
;
Myocardium
;
Ventricular Premature Complexes
9.Osteomyelitis Resulting from Chronic Septic Olecranon Bursitis: Report of Two Cases.
Myung Sang MOON ; Seong Tae KIM ; Bong Keun PARK
Clinics in Shoulder and Elbow 2016;19(4):252-255
We reported the two cases of olecranon osteomyelitis secondary to the iatrogenic chronic relapsing septic olecranon bursitis. Infection was well eradicated by excision of the infected bursa and curettage of the eroded olecranon under the coverage of antibiotic therapy.
Bursitis*
;
Curettage
;
Cytochrome P-450 CYP1A1
;
Olecranon Process*
;
Osteomyelitis*
10.The effect of free oxygen radical scavengers on the expression of ATPase of mouse epidermal langerhans cells after UVB irradiation.
Seong Jin JEON ; Kee Suck SUH ; Sang Tae KIM
Korean Journal of Dermatology 1991;29(5):574-582
No abstract available.
Adenosine Triphosphatases*
;
Animals
;
Langerhans Cells*
;
Mice*
;
Oxygen*