1.Radiological features of lower respiratory infection by respiratory syncytial virus in infants and young children.
Woo Sun KIM ; In One KIM ; Kyung Mo YEON ; Seong Hee JANG ; Hoan Jong LEE
Journal of the Korean Radiological Society 1992;28(4):639-643
Respiratory syncytial virus is the most common cause of lower respiratory infection (bronchiolitis and pneumonia) of infancy and early childhood. We analyzed clinical and radiological features of 76 patients with lower respiratory infections by respiratory syncytial virus, which were diagnosed by indirect immunofluorescent test or culture of nasal aspirate in Hep-2 cell monolayer, during the period of January-December, 1991. There were peaks of incidences in March-May and November-December, accounting for 87% of eases. Sixty-two cases (82%) were under 1 year of age. Fifty cases(66%) had underlying diseases. Major radiographical findings were overaeration (83%), parahilar peribronchial infiltrates(67%), segmental or subsegmental atelectasis(32%), and segmental or lobar consolidation(16%). In 15 cases(20%), overaeration was the only radiological findings. There was no evidence of pleural effusion or hilar lymph node enlargement in all cases. By considerig clinical features(symptoms, age. Underlying diseases, epidemic seasons) in addition to the radiological findings, radiologists would be familiar with lower respiratory infection by respiratory syncytial virus. Air space consolidation, which is generally though to represent bacterial pneumonia, is also observed not infrequently in respiratory syncytial virus infections.
Child*
;
Humans
;
Incidence
;
Infant*
;
Lymph Nodes
;
Pleural Effusion
;
Pneumonia, Bacterial
;
Respiratory Syncytial Virus Infections
;
Respiratory Syncytial Viruses*
;
Respiratory Tract Infections
2.Effects of Physical Activity on Reducing Depression and Menopausal Symptoms: A Meta-Analysis
Seong-Hi PARK ; Kuem Sun HAN ; Youn Jung JANG
Journal of Korean Academy of Psychiatric and Mental Health Nursing 2023;32(3):325-339
Purpose:
This study systematically reviewed the effects of physical activity on depression and various menopausal symptoms in middle-aged women. We aimed to identify physical activity as a useful intervention for mitigating the physiological and psychological challenges associated with menopause and promoting healthy aging.
Methods:
Electronic searches were conducted in the MEDLINE, EMBASE, CINAHL, and the Cochrane Library databases using predefined keywords “menopause” and “physical activities”. Of the 1,391 initial articles, 15 randomized controlled trials involving 1,692 middle-aged women were included.
Results:
Physical activities led to a reduction in depressive symptoms, with a standardized mean difference (SMD) of -0.60 (95% CI, -0.90 to -0.30). Moreover, all menopausal symptoms, except vasomotor symptoms, were decreased. Specifically, the SMDs for the five subscales of menopausal symptoms were as follows: total scores: -1.53 (95% CI, -2.57 to -0.49); vasomotor: -0.76 (95% CI, -1.53 to 0.00); psychological: -0.93 (95% CI, -1.62 to -0.25); physical: -1.10 (95% CI, -1.77 to -0.43); and urogenital/sexual: -0.67 (95% CI, -1.23 to -0.12).
Conclusion
Physical activity is beneficial for middle-aged women transitioning from peri- to post-menopause. Engagement in physical activity can contribute to the maintenance of overall health and well-being during aging by reducing depression and menopausal symptoms.
3.Fixation of Greater Trochanteric Fracture Using Double Strands and Double Loops with Figure of 8 Wiring in Non-cement Total Hip Arthroplasty for Unstable Intertrochanteric Fracture.
Ho Jin NAM ; Doo Hoon SUN ; Seong Won JANG
Hip & Pelvis 2012;24(4):316-321
PURPOSE: Non-cement total hip arthroplasty for unstable intertrochanteric fracture in elderly patients is regarded as another surgical technique preventing complications such as non-union, long term limitation of weight bearing, pressure sore, pulmonary thromboembolism after open reduction or closed reduction with intramedullary nailing, or plate fixation. We would like to announce the short-term results of primary non-cement total hip arthroplasty with double strands and double loops figure of 8 wiring for unstable intertrochanteric fracture in elderly patients. MATERIALS AND METHODS: All of the 20 patients admitted to the hospital between April 2010 and February 2012 who underwent non-cement total hip arthroplasty with double strands and double loops figure of 8 wiring for unstable intertrochanteric fractures were evaluated. The mean age was 71.1(57-86), there were nine males, and 11 females, with an average follow up period of six months. The post-operative state was evaluated by Harris hip score. RESULTS: The mean operation time was 95 min, and the average blood loss was 800 cc. Mean Harris hip score at the last available follow-up was 92.7, and, among the patients, 15 had all functions of daily life without limitation of walking distance, one had hip dislocation, one had breakage of strands. Pressure sore, deep vein thrombosis, and pulmonary thromboembolism were absent. Radiography at the last available follow-up showed no loosening of the femoral stem in any of the patients, and 13 patients had osteogenesis around the fracture site, and there was no osteolysis. CONCLUSION: Primary non-cement total hip arthroplasty with double strands and double loops figure of 8 wiring in elderly patients with unstable intertrochanteric fractures showed satisfactory results. These results are expected to be useful for further studies with a long-term follow-up and in development of a reduction method.
Aged
;
Arthroplasty
;
Female
;
Femur
;
Follow-Up Studies
;
Fracture Fixation, Intramedullary
;
Hip
;
Hip Dislocation
;
Hip Fractures
;
Humans
;
Male
;
Osteogenesis
;
Pressure Ulcer
;
Pulmonary Embolism
;
Venous Thrombosis
;
Walking
;
Weight-Bearing
4.A building database for emergency room and its use.
Joon Yang NOH ; Chang Soon JANG ; Seong Oung LEE ; Kyung Bin ROH ; Kee Chun HONG ; Doo Sun LEE
Journal of the Korean Society of Emergency Medicine 1993;4(1):53-66
No abstract available.
Emergencies*
;
Emergency Service, Hospital*
5.Effects of H2O2 and chlorhexidine on MMP-1, TIMP-1,2, Type 1 collagen, fibronectin and UNCL expressions in human periodontal ligament fibroblasts.
Seong Mi CHOI ; Hyun Seon JANG ; Byung Ock KIM
The Journal of the Korean Academy of Periodontology 2008;38(4):645-656
PURPOSE: To evaulate the effects of chlorhexidine and H2O2 on matrix metalloproteinase-1 (MMP-1), tissue inhibitor of metalloproteinase(TIMP-1, TIMP-2), Type 1 collagen, fibronectin and UNCL expressions in human periodontal ligament fibroblasts (hPDLF). MATERIALS AND METHODS: 1.2x10(-1)%, 1.2x10(-2)% and 1.2x10(-3)% CHX and 3x10(-3)%, 3x10(-4)% and 3x10(-5)% H2O2 and mixture of CHX and H2O2 were applied to hPDLF for 1 min and 30 min. The mRNA expressions of MMP-1, TIMP-1 and 2, Type 1 collagen, fibronectin and UNCL in hPDLF were analysed by RT-PCR. RESULTS: The result were as follows: 1. The expression of UNCL mRNA was higher than that of other mRNAs. 2. 1.2x10(-3) % CHX increased mRNA expressions of hPDLF as application time increased. 3. H2O2 lower than 3x10(-3) % increased expression of UNCL mRNA, and did not decrease mRNA expression of hPDLF. 4. hPDLF treatment with 1.2x10(-1) % CHX (with or without H2O2) resulted in no gene expression. 5. hPDLF treatment with 1.2x10(-2) % CHX (with or without H2O2) for 30 minutes resulted in no gene expression. CONCLUSION: Because low concentration of CHX and H2O2 increased UNCL mRNA expression of hPDLF, low concentraction of CHX and H2O2 may have an antioxidative effect.
Chlorhexidine
;
Collagen Type I
;
Fibroblasts
;
Fibronectins
;
Humans
;
Matrix Metalloproteinase 1
;
Periodontal Ligament
;
RNA, Messenger
;
Tissue Inhibitor of Metalloproteinase-1
6.SHEAR BOND STRENGTH OF RESIN ADHESIVE CEMENT TO ENAMEL AND Ni-Cr-Be ALLOY.
Sun Hyung LEE ; Jae Ho YANG ; Hun Young CHUNG ; II Seong JANG
The Journal of Korean Academy of Prosthodontics 1997;35(2):365-372
This study was executed to measure the shear bond strength of Panavia EX and Panavia 21 when the Ni-Cr-Be alloy castings were cemented to the enamel surfaces with these cements. The cast metsl plates of Ni-Cr-Be alloy were sandblasted and cemented to acid etched enamel surface with Panavia EX or Panavia 21. Their shear bond strength were measured with Instron Universal Testing machine. Within the limits of this study, following conclusions were withgdrawn. 1. The mean shear bond strength were 26.85.7Mpa, in Panavia EX and 28.35.2Mpa, in Panavia 21. 2. t-Test revealed no statistical significance between two groups(.05 level) 3. Macroscopically, bond failures were revealed compound fracture at metal and enamel interfaces, in cases of both cements, as the cement attached partly on both metal and enamel surface.
Adhesives*
;
Alloys*
;
Dental Enamel*
;
Fractures, Open
7.A Study on Systolic Time Intervals during Second, Third Trimesters and Postpartum Period.
Kyoung Sig JANG ; Bynng Hyun SEONG ; Hak Yeon BAE ; Jae Sun MUN ; Min Hyung LEE ; Hyun Kwan OH
Korean Circulation Journal 1981;11(2):93-99
Systolic time interval measurements were made sequentially during second, third trimesters and postpartum period. Recordings were made in the supine position after bed rest for at least five minutes in order to obtain a steady state. In second trimester, pre-ejection period index (PEPI) was significantly shortened and left ventricular ejection period index(LVETI) remained normal while PEP/LVET decreased. Four possible mechanisms may be involved to account for the alterations in hemodynamic changes during this period(late stage of second trimester) : (1) increased metabolic demands of pregnancy: (2) hemodynamic effects of hypervolemia: (3) circulatory adjustments secondary to an arteriovenous shunt-like effect of the placental circulation: (4) cardiovascular effect of steroid hormone. The third trimester was characterized-by a markedly shortened LVETI, a prolonged PEPI and PEP/LVET. This findings are consistent with impaired left ventricular performance and are probably due to decreased left ventricular preload resulting from diminished venous return secondary to inferior vena caval obstruction by the large gravid uterus. In the postpartum period, the PEPI and PEP/LVET remained elevated and the LVETI shortened in the supine position. It is concluded that alterations in systolic time intervals occur normally during the course of uncomplicated pregnancy and persist into the postpartum period.
Bed Rest
;
Female
;
Hemodynamics
;
Humans
;
Placental Circulation
;
Postpartum Period*
;
Pregnancy
;
Pregnancy Trimester, Second
;
Pregnancy Trimester, Third*
;
Supine Position
;
Systole*
;
Uterus
8.An Individualized Teaching Program for Atherosclerotic Risk Factor Reduction in Patients with Myocardial Infarction.
Hye Sun JEONG ; Jang Seong CHAE ; Jung Soon MOON ; Yang Sook YOO
Yonsei Medical Journal 2002;43(1):93-100
This study was conducted to evaluate the effect of a teaching program on patients with myocardial infarction. Forty-five patients were randomly selected 22 were assigned to a teaching group and 23 to a control group. An individualized teaching program was delivered to the teaching group during the hospitalization period. It covered aspects such as: the characteristics of heart disease, the anatomy and physiology of the heart, risk factors of atherosclerosis, medication and diet and exercise therapy. When these subjects were discharged to their homes, they received regular supportive care via telephone or mail for 12 weeks. Atherosclerotic risk factors, including, smoking, exercise, blood lipid profile and BMI were measured before and after the teaching program. Post-testing revealed that the numbers of those who exercised and the number of non-smokers were significantly higher in the teaching group than in the control group. Increased HDL cholesterol (High-Density Lipoprotein cholesterol) was significantly greater in the teaching group than in the control group. The above findings suggest that this individualized teaching program might be helpful at reducing the risk factors of atherosclerosis in myocardial infarction patients.
Adult
;
Aged
;
Arteriosclerosis/etiology/*prevention & control
;
Comparative Study
;
Exercise
;
Female
;
Human
;
Lipids/blood
;
Male
;
Middle Age
;
Myocardial Infarction/*prevention & control
;
*Patient Education
;
Risk Factors
;
Smoking
9.Expression of c-jun by X-ray According to Cell Growth State in CaSki Cell Line.
Seong Sun JANG ; Woo Yoon PARK
The Journal of the Korean Society for Therapeutic Radiology and Oncology 1999;17(3):223-229
PURPOSE: The expression pattern of c-jun by ionizing radiation according to cell growth state (exponential growth phase vs. stationary phase) and its relationship with cell cycle redistribution were investigated. MATERIALS AND METHODS: The exponential growth phase (day 4) and stationary phase (day 9) cells were determined from cell growth curve according to the elapse of days in CaSki. The cells were irradiated using 6 MV X-ray with a dose of 2 Gy at a fixed dose rate of 3 Gy/min. Northern blot analysis was performed with total cellular RNA and cell cycle distribution was analyzed using flow cytometry according to time-course after irradiation. RESULTS: The maximum expression of c-jun occurred 1 hour after irradiation in both exponential growth and stationary phase cells. After then c-jun expression was elevated upto 6 hours in exponential growth phase cells, but the level decreased in stationary phase cells. Movements of cells from G0-G1 to S, G2-M phase after irradiation were higher in exponential growth phase than stationary phase. CONCLUSION: c-jun may be involved in the regulation of cellular proliferation according to the growth states after irradiation.
Blotting, Northern
;
Cell Cycle
;
Cell Line*
;
Cell Proliferation
;
Flow Cytometry
;
Radiation, Ionizing
;
RNA
10.Clinical Applications of Digital Subtraction Angiography(DSA) in Neurosurgical Field.
Seong Hyung KIM ; Sun Gwan CHOI ; Bark Jang BYUN ; In Soo LEE
Journal of Korean Neurosurgical Society 1985;14(1):93-102
Methods for the identification and amplification of signals from quantities of intravascularly administered iodinated contrast agent and their combination with image subtraction have evolved into a clinically useful technique called digital subtraction angiography (DAS). The initial motivation for the development of DSA was the desire to replace standard conventional angiographic procedures with simpler, less invasive techniques. We have evaluated IV-DSA and IA-DSA which are made in 150 patients with clinically suspected intracranial diseases from Dec. 1983 to Mar. 1985. Comparison with IA-DSA and conventional angiography indicated that the quality and information of content of the film were equivalent. IV-DSA image quality was inferior to that of conventional angiography. But IV-DSA can be used for intracranial studies to evaluate results of surgery of aneurysm, AVM or tumor and to revaluate vasospasm after subarachnoid hemorrhage before surgery. Also, IV-DSA can be used for neck vessel appearance due to reveal adequate information.
Aneurysm
;
Angiography
;
Angiography, Digital Subtraction
;
Humans
;
Motivation
;
Neck
;
Subarachnoid Hemorrhage