A Prospective study was done about incidence and treatment of hemodynamically significant' patent ductus arteriosus in premature infants admitted to neonatal intensive care unit of Ewha University Hospital from Feb. 1984 for one year. The results were as follows; 1) Among 46 infants with birth weight less than 2,000gm and gestational period 36 wks, 15(32.6%) developed a hemodynamically significant PDA. 2) The incidence of respiratory distress syndrome was six times higher in PDA group than that of non-PDA group(73.3% vs 12.9%). 3) The need for ventilatory assistance was five times higher in PDA group than that of non-PDA group(80% vs 16.1%). 4) The mortality rate was 40% in PDA group, 15% in non-PDA group. 5) The ratio of left atrium to aorta(LA/AO) in M-mode echocardiography was significantly higher in PDA group than that of non-PDA group(1.21+/-0.18 vs 0.93+/-0.23). 6) Indomethacin treated with usual medical therapy resulted in ductal closure in 80%, 20% with usual medical therapy only. 7) The mean LA/AO ratio was significantly decreased after indomethacin treatment(1.15+/-0.13 vs 1.21+/-0.18). 8) The change of the value of plasma sodium and potassium was not significant during indomethacin therapy, whereas BUN, creatinine value was increased during treatment, but that was reversible.
Birth Weight ; Creatinine ; Ductus Arteriosus, Patent* ; Echocardiography ; Heart Atria ; Humans ; Incidence ; Indomethacin ; Infant ; Infant, Newborn ; Infant, Premature* ; Intensive Care, Neonatal ; Mortality ; Plasma ; Potassium ; Prospective Studies ; Sodium

The electrocardiography was performed to the 95 patients(58 male, 37 female) with chronic anemia in Department of Internal Medicine, Busan City Hospital, Busan University Hospital, Busan paik Hospital In-Je Medical College, Busan korea between April 1978 and March 1981. The hemoglobin levels were 4 Gm%-10Gm%, and the symptoms such as dizziness, palpitation, weakness, and appetite loss were continued for 6 months or more. The results were as following: 1. The abnormal electrocardiographic changes were observed in 49 of the 95 chronic anemic patients. 2. Prolonged QTc interval was observed in 12(12.6%) of 95 cases, depressed ST segment in 48(50.5%), inverted T wave in 32(33.7%), LVH in 31(32.6%), low voltage in 5(5.3%), and Rt. B.B.B. in 5(5.3%). 3. In the Hb level of 4.0~5.9Gm% 20% of the total 95 patients revealed prolonged QTc interval, 86.7% depressed ST segment, 40% inverted T wave, 20% LVH, 6.7% Rt. B.B.B., in the Hb level of 6.0~7.9Gm 10.6% prolonged QTc interval, 39.3% depressed St segment, 42.9% inverted T wave, 39.3% LVH, 3.6% low voltage and in the Hb level of 8.0-9.9Gm% 11.5% prolonged QTc interval, 46.1% depressed ST segment, 27% inverted T wave, 32.7% LVH and 7.7% low voltage.
Anemia* ; Appetite ; Busan ; Dizziness ; Electrocardiography* ; Hospitals, Urban ; Humans ; Internal Medicine ; Korea ; Male

The 26 year old male with the hypertrophic cardiomyopathy confirmed by M-mode and 2-D echocardiography is reported with the review of the literatures.
Adult ; Cardiomyopathy, Hypertrophic* ; Echocardiography ; Humans ; Male

No abstract available.
Anemia, Iron-Deficiency* ; Hypoproteinemia* ; Iron*

Statistical observation was made on the 1949 patients with cardiovascular diseases who had been treated in Dept. of Internal Medicine, Seoul national University Hospital during the period of four years, from jan. 1972 to Dec. 1975. 1) The patients wth cardiovascular diseases accounted for 20.2% out of total 9,638 medical inpatients. The incidence for the consecutive years was not apparently variable. 2) The diseases occured most frequently in the sixth decades and the incidence decreased in the order of fifth and seventh decades. 3) The disease was more prevalent in male than female with ratio of 1.3 of 1. 4) The hypertension was the most common disease among cardiovascular diseases, accounting for 67.5% of patients with cardiovascular diseases and 13.6% of total medical inpatients. The disease occurred most frequently in the sixth decades and the incidence decreased in the order of fifth and seventh decades with male preponderance. 81.8% of patients with hypertension was essential hypertension and 18.2% was secondary hypertension. Secondary hypertension was caused by parenchylmal renal diseases in most patients and there were only several patients with renovascular and endocrine hypertension. 40.2% of patients with essential hypertension had no complications, 38.6% had cerebral vascular accidents, 12.1% had uremia and 9.1% had congestive heart failure. The patients with malignant hypertension was 9.6% of total patients with hypertension. 5) Rheumatic heart disease was 14% of patients with cardiovascular diseases, being second in incidence. It was more prevalent in female than male with ratio of 1 male to 1.3 female and affected the mitral valve in most of the cases, whereas involvement of aortic valve was rare. 6) The coronary heart disease was 5.3% of patients with cardiovascular diseases, being third in incidence. It occured most frequently in seventh and sixth decades and affected male two times more frquently than female. 7) The congenital heart disease was 2.9% of patients with cardiovascular diseases, of which atrial septal defect was highest in incidence. 8) The cor-pulmonale was 1.4%, pericarditis 1.4%, endocarditis 0.9%, postpartum heart disease 1.2%, myxedematous heart disease 0.2%, arrhythmia 2.1%, peripheral vascular disease 1.1% and miscellaneous 0.6% of patients with cardiovascular diseases. 9) Postpartum heart failure and endocarditis was remarkably decreased in incidence recently and there were one patients with beriberi heart disease and one patient with syphilitic heart disease during those years of this study.
Aortic Valve ; Arrhythmias, Cardiac ; Beriberi ; Cardiovascular Diseases* ; Coronary Disease ; Endocarditis ; Female ; Heart Defects, Congenital ; Heart Diseases ; Heart Failure ; Heart Septal Defects, Atrial ; Humans ; Hypertension ; Hypertension, Malignant ; Incidence ; Inpatients ; Internal Medicine ; Korea* ; Male ; Mitral Valve ; Pericarditis ; Peripheral Vascular Diseases ; Postpartum Period ; Rheumatic Heart Disease ; Seoul ; Uremia

No abstract available.
Autoantibodies* ; Incidence* ; Interferon-gamma*

No abstract available.
Child* ; Heart Defects, Congenital* ; Humans

We evaluated the therapeutic effect of potassium iodide in fourteen patients with erythema nodosum. The results were as follows: 1) All patients were given a saturated solution of potassium iodide, 600 to 900 mg orall y a day for 3 days to 5 weeks. 2) Three patients were observed initial days, two patients within 9 days. 3) There were no correlations between therapeutic effect of potassium iodide. 4) Specific side effects were not found during the treatment with potassium iodide.
Erythema Nodosum* ; Erythema* ; Humans ; Potassium Iodide* ; Potassium*

This treatise summarizes the medical facts about the persistent vegetative state(PVS) and the associated issues. In August 1998, the opinions of the 380 neurologists and the 1007 neurosurgeons are inquired about the diagnostic criteria of PVS, the degree and the withdrawal of treatment on PVS patients. The response rate is 18.8%. The diagnostic criteria of PVS is determined by the items approved above 5007o of responses. (1) no evidence of cerebral function and an inability to interact with visual, auditory stimuli and follow commands. (2) maintaining the respiratory function with spontaneous respiration and normal respiratory pattern. (3) spontaneous eye opening and eye ball movements without sustained tracking. (4) variably preserved brain stem reflexes. (5) presence of sleep-wake cycles. (6) (1)-(5) symptoms should be persist for 6 months after the development of vegetative state. (7) the diagnostic criteria of PVS should be applied more than 3 times during the minimum observation period. (8) this diagnostic criteria of PVS could be applied to adults over 7 ages. As to the degree of treatment, nasogastric tube feeding and air-way keeping through the tracheostomy are approved over 9007b. Also antibiotics can be used in infection. As to the withdrawal of treatment, do not resuscitate order of patient s family is accepted by 46.1% in an emergency condition like cardiac arrest. But discharge against medical advice by the patient s family is accepted by 73.107o in non-emergency condition. In the case of neonates, parents decision is more determinative than any other thing.
Adult ; Anti-Bacterial Agents ; Brain Stem ; Emergencies ; Enteral Nutrition ; Heart Arrest ; Humans ; Infant, Newborn ; Korea* ; Parents ; Persistent Vegetative State* ; Reflex ; Respiration ; Tracheostomy

Forty-five patients with primary neoplasm of the spine, disgnosed and operated at Dept. of Orthopedic Surgery, Seoul National University Hospital, from 1970 to 1988, were reviewed in an attempt to analyze the incidence of the primary spine tumors and effectiveness of surgical treatment. Mean follow-up was 2.5 years. Among 29 benign tumors, 7 cases of osteoid osteoma, 6 cases of giant cell tumor, 4 cases of osteoblastoma and aneurysmal bone cyst, and 2 cases of fibrous dysplasia and osteochondroma, and others were identified. Of 16 malignant tumors, 6 cases of eosinophilic granuloms, 4 cases of chordoma, 3 cases of solitary plasmacytoms, and others were noted. 17 cases occurred in the anterior compartment, 18 cases in the posterior compartment, and 10 cases involved both compartments. Surgical treatment consisted of complete or near complete excision, decompression, and additional stabilization procedure when the stability of the vertebral column was compromised. Stablization was achieved either by fusion, strut bone graft, or by additional Zielke, Cotrel-Dubousset, or Luque-Harringtion instrumentation. The results were astisfactory in most of the cases with benign tumors except cases of giant cell tumor. The results in malignant tumor were satisfactory especially in eosinophilic granuloma and solitary plasmacytoma with respects to symptoms and survival, and this fact was attaibuted to good response to adjuvant chemotherapy and radiation therapy. Recent application of Cotrol-Dubousset or Zielke instrumentation after agressive resection made early ambulation a clinical reality.
Aneurysm ; Bone Cysts ; Chemotherapy, Adjuvant ; Chordoma ; Decompression ; Early Ambulation ; Eosinophilic Granuloma ; Eosinophils ; Follow-Up Studies ; Giant Cell Tumors ; Humans ; Incidence ; Orthopedics ; Osteoblastoma ; Osteochondroma ; Osteoma, Osteoid ; Plasmacytoma ; Seoul ; Spine ; Transplants