A Prospective study was done about incidence and treatment of hemodynamically significant' patent ductus arteriosus in premature infants admitted to neonatal intensive care unit of Ewha University Hospital from Feb. 1984 for one year. The results were as follows; 1) Among 46 infants with birth weight less than 2,000gm and gestational period 36 wks, 15(32.6%) developed a hemodynamically significant PDA. 2) The incidence of respiratory distress syndrome was six times higher in PDA group than that of non-PDA group(73.3% vs 12.9%). 3) The need for ventilatory assistance was five times higher in PDA group than that of non-PDA group(80% vs 16.1%). 4) The mortality rate was 40% in PDA group, 15% in non-PDA group. 5) The ratio of left atrium to aorta(LA/AO) in M-mode echocardiography was significantly higher in PDA group than that of non-PDA group(1.21+/-0.18 vs 0.93+/-0.23). 6) Indomethacin treated with usual medical therapy resulted in ductal closure in 80%, 20% with usual medical therapy only. 7) The mean LA/AO ratio was significantly decreased after indomethacin treatment(1.15+/-0.13 vs 1.21+/-0.18). 8) The change of the value of plasma sodium and potassium was not significant during indomethacin therapy, whereas BUN, creatinine value was increased during treatment, but that was reversible.
Birth Weight ; Creatinine ; Ductus Arteriosus, Patent* ; Echocardiography ; Heart Atria ; Humans ; Incidence ; Indomethacin ; Infant ; Infant, Newborn ; Infant, Premature* ; Intensive Care, Neonatal ; Mortality ; Plasma ; Potassium ; Prospective Studies ; Sodium

No abstract available.
Humans ; Male* ; Phenobarbital* ; Young Adult*

No abstract available.
Humans ; Young Adult*

No abstract available.
Humans ; Male* ; Phenobarbital* ; Young Adult*

No abstract available.
Humans ; Young Adult*

We reported the two cases of olecranon osteomyelitis secondary to the iatrogenic chronic relapsing septic olecranon bursitis. Infection was well eradicated by excision of the infected bursa and curettage of the eroded olecranon under the coverage of antibiotic therapy.
Bursitis* ; Curettage ; Cytochrome P-450 CYP1A1 ; Olecranon Process* ; Osteomyelitis*

The managements of fractures of shaft of the femur in children differ in manyways from those in adults. The union occurs rapidly and the remodelling of bone assists in realignment as the child grows. However, the greatest difference observed in the two groups is that in children the growing bone tends to respond to fracture and other influences with growth acceleration. Among the many kinds of methods in the treatment of femoral shaft fractures in children, we have used the method of skeletal traction with Charnleys balanced traction unit due to 1) Fixed traction that introduces the length remaining constant, 2) Weight traction, the tension remaining constant, 3) Eaay control of alignment, that is controlled by the splint not by the traction force, especially in correcting the deformity of retroflexion angulation. Twenty-two cases of fracture of the femoral shaft in children treated with skeletal traction in that method at Korea General Hospital during 4 years, were analyzed. The purpose of this study was, through a series of follow up examination, to elucidate to what extent fracture of the femoral shaft in children gives us increased longitudinal growth of the fractured bone as compared with the healthy limb. The result revealed that in about 72.7% of children with fracture of the frmoral shaft, the leg length discrepancy was within the range of 0+1 cm. The period of accelerated growth was between 6 months and g months after the fracture. Corrected angle at fracture site was noted 3.2 from 10.7 that had been measured as good callus formation.
Acceleration ; Adult ; Bony Callus ; Child ; Congenital Abnormalities ; Extremities ; Femur ; Follow-Up Studies ; Hospitals, General ; Humans ; Korea ; Leg ; Methods ; Splints ; Traction

Stability, mobility, and freedom from pain are the requirements of a normal knee. Arthrodesis of a knee damaged by disease or injury will satisfy two of the three requirenents. The current status of knee replacement surgery suggests that high density polyethylene and chrome cobalt alloy or stainless steel are acceptable materials for use in the intra-articular environment of knee. These prosthetic components of artificial knees can be firmly cemented into bone and provide acceptable slinical results if used within their design limits. We have had 3 total knee replacements in the chronic rheumatoid patients. The results of 2 Geometric knee replacements and 1 Guepar knee replacement were assessed from 5 months to 2 years after operation. Total knee replacement improved mobility and reduced pain in these patients.
Alloys ; Arthrodesis ; Arthroplasty, Replacement, Knee ; Cobalt ; Freedom ; Humans ; Knee ; Polyethylene ; Stainless Steel

BACKGROUND: Periungual warts are a therapeutic challenge. Many studies have revealed that intralesional interferon α-2b therapy and pulsed dye laser therapy have numerous advantages over other modalities of theratment. OBJECTIVE: The purpose of this study was to determine if combination therapy with intralesional interferon α-2b and pulsed dye laser might offer an effective treatment for periungual warts. METHODS: Thirty-three patients were randomly assigned to one of three study groups. In group A, the patients received both intralesional interferon α-2b treatment and pulsed dye laser(PDL) therapy (n=13). Group B patients were treated wit intralesional interferon α-2b alone (n=10) and group C was done with PDL therapy only (n=10). RESULTS: The clearance rate was 92.3% for the patients treated with the combination therapy of intralesional interferon α-2b treatment and pulsed dye laser (PDL) therapy. It was 50% for the patients with the intralesional interferon α-2b treatment alone, and 0% for the group with the PDL therpy only. No significant side effects were observed. At 6 months after cessation of the therapy, total 2 cases (one from group A and the other from group B) were recurred. CONCLUSION: The combination therapy with intralesional interferon α-2b treatment and pulsed dye laser therapy was highly effective for the treatment of recalcitrant periungual warts.
Humans ; Interferons* ; Lasers, Dye* ; Warts*

Primary gout is a metabolic disease that has its basis in an inborn error in the intermediary metabolism of purines and related compounds. It is characterized by hyperuricemia, recurrent attacks of acute arthritis, deposition of monosodium urate crystals in and around the joints of the extremities, urolithiasis, renal and cardiovascular disease. Thirty-eight patients with gout managed at the department of orthopaedic surgery, Dong-A University Hospital, from April, 1990 to November 1993, had been reviewed retrospectively and the following results were obtained. 1. Most of cases were male(95%) and the mean age was 55.4 years old. 2. The case of first attack was 8 cases(21%), the most common age of first attack was fifth decade and mean duration of disease was 7.4 years. 3. The most common precipitating factor was overindulgence in food and alcohol. 4. The avarage uric acid level of serum and that 24-hour urine collection in acute attacks were 11.2 mg/dl and 24.5mg/D. Respectively all of the cases except four revealed increased ESR (average 43 mm/hr). 5. When the acute attack was developed, the most common involved joint was the first M-P joint (83%) of the foot, but as the acute gout was progressed to the chronic form, multiple joints were affected. 6, The punched out lesion in the radiograph was found in 7 cases(25 joints), among them 6 cases had suffered from the disease for longer than 3 years. 7. The most common complication was nephropathy(18 cases). 8. In case of acute gouty attack, we administered colchicine in the 22 cases. The therapeutic method of colchicine usually consisted of oral administration of 2 tablets(1.3mg) initially, followed by 1 tablet(0.65mg) every hour untill the relief of joint pain or the development of gastointestinal symptoms. We rocomended 6-8 tablets of colchicine for the management of acute gouty attack with safety. 9. Colchicine in small daily dose(0.65mg qd or bid) could be effective to prevent the recurrent attacks of high risk gouty arthritis.
Administration, Oral ; Arthralgia ; Arthritis ; Arthritis, Gouty ; Cardiovascular Diseases ; Clinical Study ; Colchicine ; Extremities ; Foot ; Gout ; Humans ; Hyperuricemia ; Joints ; Metabolic Diseases ; Metabolism ; Methods ; Precipitating Factors ; Purines ; Retrospective Studies ; Tablets ; Uric Acid ; Urine Specimen Collection ; Urolithiasis