1.A case of porokeratosis induced by topical PUVA in a vitiligo patient.
Ho Seong LEE ; Jin Soo KANG ; Ki Beom PARK
Korean Journal of Dermatology 1992;30(1):131-134
A 20-year-old female, who had been treated with topical PUVA therapy for her vitiligo, developed characteristic skin lesions of disseminated superficial artiric porokeratosis(DSAP). All of her three sisters had vitiligo and had been treated with topica PUVA, hut only one developed DSAP lesion. Her mother had had DSAP lesions on expcsec areas for 20 years. DSAP shows an autosomal dominant mode of inheritance, and is charaterized by multiple ciark brownish keratotic papaules surrounded by slightly elevatied order. The exacerbation of the lesion by exposure t.o UV lignt indicates that the regulatingene for DSAP is related to sunlight. 1-lerein we reported a case of DSAP induced by topica] PUVA therapy in one patient during management of familial vitiligo in 3 sisters.
Female
;
Humans
;
Mothers
;
Porokeratosis*
;
PUVA Therapy
;
Siblings
;
Skin
;
Sunlight
;
Vitiligo*
;
Wills
;
Young Adult
2.Injury of Renal Artery Branches by Blunt Trauma: Arteriographic Findings and Transarterial Embolotherapy.
Heoung Keun KANG ; Jeong Jin SEO ; Jae Kyu KIM ; Woong YOON ; Seong Nam CHU ; Yun Hyeun KIM ; Kwang Seong PARK
Journal of the Korean Radiological Society 1995;32(5):783-787
PURPOSE: The purpose of this study was to describe the anglographic finding and clinical result of transarterial embolotherapy(TAE) in patients with injuries of renal artery branches by blunt trauma. MATERIALS AND METHODS: The study was based on retrospective analysis of seven cases, in which TAE was attempted for the control of traumatic renal arterial bleeding. All procedures were performed via the transfemoral approach. TAE was performed with stainless steel coil in two cases, Gelfoam in one case, and Gelfoam and stainless steel coil in four cases. RESULTS: Angiographic findings of vascular injuries were pseudoaneurysm in four cases, extravasation in two cases and arteriocalyceal fistula in one case. All procedures were performed successfully without complication. CONCLUSION: Pseudoaneurysm is a common anglographic finding in patients with injury of renal artery branches and TAE is considered a safe and effective method for treating such cases.
Aneurysm, False
;
Embolization, Therapeutic*
;
Fistula
;
Gelatin Sponge, Absorbable
;
Hemorrhage
;
Humans
;
Renal Artery*
;
Retrospective Studies
;
Stainless Steel
;
Vascular System Injuries
3.Differences of calvarial graft survival according to circulation sources.
Seong Geun PARK ; Ki Hwan HAN ; Jin Sung KANG ; Kwan Kyu PARK
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1993;20(1):61-72
No abstract available.
Graft Survival*
;
Transplants*
4.Clinical observation of Osteomyelitis in Childhood.
Seong Gyoo PARK ; Young Suk HONG ; Se Jin KANG ; Sun Gyum KIM ; Pyung Hwa CHOI
Journal of the Korean Pediatric Society 1990;33(4):499-505
No abstract available.
Osteomyelitis*
5.A Case of Postirradiation Uterine Papillary Serous Carcinoma.
Jin Woo SHIN ; Eung Seok LEE ; In Sun KIM ; Jae Seong KANG
Korean Journal of Obstetrics and Gynecology 2000;43(6):1106-1108
Uterine papillary serous carcinoma is a morphologically distinct variant of endometrial carcinoma that is associated with an aggressive behavior with rapid progression and high recurrence, and poor response to salvage treatment. The most common type of malignancy developing in the uterus after radiation therapy is the malignant mixed mullerian tumor, however, the papillary serous carcinomas have rarely been reported.Here we report a case of uterine papillary serous carcinoma which had developed 7 years after radiation therapy for invasive cervical cancer.
Endometrial Neoplasms
;
Female
;
Recurrence
;
Uterine Cervical Neoplasms
;
Uterus
6.Is CT Effective in Diagnosing the Acute Appendicitis?: Focus on Comparison of Unenhanced CT with Barium Enema.
Seong Hee CHOI ; So Hee HAHM ; Jin Hwa KANG ; Jeong Hwa MOON
Journal of the Korean Radiological Society 1994;31(1):91-98
PURPOSE:To evaluate the role of unenhanced CT in diagnosing the acute appendicitis. METHOD AND MATERIALS: We retrospectively analyzed conventional contrast-enhanced abdominal CT scans of 197 normal patients and barium enemas of 26 out of the 197 patients. Additional unenhanced CT scans of right lower abdomen were performed on 30 patients who were suspected of having acute appendicitis;barium enema was performed in 26 patients. RESULTS: in the analysis of the conventional CT scans, we could detect 132(67%) normal appendicies. On barium enema of 26 out of 197 patients, abruptly narrowed appendix was visualized in 5 cases and luminal irregularity in 4 cases but all 26 cases showed normal appendix on CT. In the 30 cases of unenhanced CT, all appendicies were visualized. Among 12 Cases which were proved as acute appendicitis, barium enenma was done in 10 case;abruptly narrowed appendix was shown in 3 and luminal irregularity in 1. Among 18 cases which were diagnosed as normal appendix, nonvisualization of appendix' was in 1 case, abruptly narrowed lumen in 3, and luminal irregularity in 9. CONCLUSION:Unenhanced CT in the area of the cecum may be an effective and safe diagnostic tool for acute appendicitis.
Abdomen
;
Appendicitis*
;
Appendix
;
Barium*
;
Cecum
;
Enema*
;
Humans
;
Phenobarbital
;
Retrospective Studies
;
Tomography, X-Ray Computed
7.Studies on the VP4 and VP7 Genes of Bovine Rotaviruses from Field Samples Using RT-PCR and RFLP Analysis.
Seong Jin JEON ; Shien Young KANG ; Chung Ho CHANG ; Chung Won CHUNG ; Won Yong KIM
Journal of the Korean Society of Virology 1998;28(2):165-174
Characterizations of the VP4 (P type) and VP7 (G type) genes of Korean isolates of bovine rotavirus were performed using RT-PCR/RFLP and nucleotide sequencing analysis. After RT-PCR amplification of partial length (1094bp) of the VP4 and full length (1062bp) of the VP7 genes, amplified PCR products were digested with restriction endonucleases and digestion patterns were compared with those of reference rotaviruses. With the VP4 genes, four RFLP (AD) profiles were observed; three (A, B and C) were the same as those of bovine rotavirus NCDV (P[1]), IND (P[5]) and B223 (P[11]), respectively, Profile D was the same as that of porcine rotavirus OSU (p[7]). With the VP7 genes, five RFLP profiles (I-V) were observed; three of them (1, II and III) were the same as those of bovine rotavirus NCDV (G6), Cody I-801 (G8), and B223 (G10), respectively, Profile IV and V were atypical to those of reference bovine rotaviruses used in this study. These two profiles were identified as G6 and G5, respectively, after analyzing and comparing the nucleotide sequences. The G typing analysis revealed that 61.9% (26/42) were G6, which included G6 subtype; 28.6% (12/42) were G5; 7.1% (3/42) were G10; 2.4% (1/42) were G8. The P typing analysis revealed that 54.8% (23/42) were P(5); 28.6% (12/42) were P(7); 11.8% (5/42) were P(11); 4.8% (2/42) were P(1). Our results showed that G6/P(5) were the most prevalent rotaviruses in diarrheic calves in Korea. Also, this is the first report that G5P(7) rotaviruses were identified from cattle with diarrhea.
Animals
;
Base Sequence
;
Cattle
;
Diarrhea
;
Digestion
;
DNA Restriction Enzymes
;
Korea
;
Polymerase Chain Reaction
;
Polymorphism, Restriction Fragment Length*
;
Rotavirus*
8.Neuroendocrine Carcinoma of the Gallbladder Arising as Double Tumor.
Dae Hyun BAEK ; Seong Ki MIN ; Jin Man KIM ; Kwang Sun SUH ; Dae Young KANG
Korean Journal of Pathology 1990;24(3):299-303
Pleomorphic (undifferentated) carcinoma is a rare histologic type of carcinomas of the gallbladder and an atypical carcinoid is thought to be an intermediated type between carcinoid tumor and small cell carcinoma. Dense core "neurosecretory" granules can be found in the above mentioned tumors. We experienced a case of a double tumor of the gallbladder in a 51-year old male patient. Grossly, a large solid mass, about 5.0 cm in diameter, was found in the fundic portion and the neck portion also had a small 1.5 cm-sized polypoid mass. Microscopically, these lesions had features of pleomorphic carcinoma and atypical carcinoid, respectively. Immunohistochemically, they manifested reactivity for neuron specific enolase. Ultrastructural study revealed neurosecretory granules in the cytoplasms of tumor cells of the fundic and neck masses. Although light microscopic features of these tumor masses are quite different, we consider that these tumors represent a spectrum of neuroendocrine differentiation.
Male
;
Humans
9.Psychophysiological Characteristics of Chronic Pain Patients Measured by Biofeedback System.
Jin Seong LEE ; Do Hyung KANG ; Hyun Ju AN ; Dae Hyun YOON ; Do Un JEONG
Sleep Medicine and Psychophysiology 2009;16(2):79-84
OBJECTIVES: Chronic pain is one of the most common experiences of humans and a typical psychophysiological disorder. The aim of this study was to measure the psychophysiological responses in chronic pain patients using a biofeedback system, and to compare them with the results from normal healthy subjects. METHODS: Forty two patients with chronic pain (17 males and 25 females, average age 44.67+/-11.10 years) and 42 normal healthy controls (17 males and 25 females, average age 45.17+/-10.46 years) participated in this study. Electromyography (EMG), skin conductance (SC), and skin temperature (ST) were recorded using biofeedback system during the 3 phases (baseline, stress, and recovery) of stress reactivity test, and average values of them were calculated. Difference of values between two groups in each corresponding phase was analyzed with independent t-test, and change of values across phases of stress reactivity test was analyzed with paired t-test (all two-tailed, p<0.05). RESULTS: Compared to normal controls, chronic pain patients had higher value of EMG (baseline : 8.10+/-5.97 micronV vs 4.72+/-1.52 micronV, t=-3.56, p<0.01 ; stress : 11.25+/-6.89 micronV vs 8.49+/-4.78 micronV, t=-2.13, p<0.05 ; recovery : 7.12+/-3.77 micronV vs 4.78+/-1.59 micronV, t= -3.70, p<0.01) and SC (baseline : 1.06+/-1.0 micronS vs 0.42+/-0.29 micronS, t=-4.0. p<0.01 ; stress : 1.87+/-2.05 micronS vs 1.03+/-0.86 micronS, t=-2.47, p<0.05 ; recovery : 1.74+/-1.77 micronS vs 0.64+/-0.59 micronS, t=-3.8, p<0.01) in all the 3 phases. But, skin temperature comparison did not reveal significant differences in all the 3 phases between two groups. CONCLUSION: Psychophysiological responses of chronic pain patients in stress reactivity test were different from those of normal healthy controls. These results suggest that sympathetic nervous system is more activated in chronic pain patients.
Biofeedback, Psychology
;
Chronic Pain
;
Electromyography
;
Female
;
Humans
;
Male
;
Psychophysiologic Disorders
;
Psychophysiology
;
Skin
;
Skin Temperature
;
Sympathetic Nervous System
10.The Effect of Melatonin on Mouse Jejunal Crypt Cell Survival and Apoptosis.
Jin Oh KANG ; Eun Young HA ; Hyung Hwan BAIK ; Yong Ho CHO ; Seong Eon HONG
The Journal of the Korean Society for Therapeutic Radiology and Oncology 2000;18(1):59-66
PURPOSE: To evaluate protective mechanism of melatonin against radiation damage and its relationship with apoptosis in mouse jejunum. MATERIALS AND METHODS:' 168 mice were divided into 28 groups according to radiation dose and melatonin treatment. To analysis crypt survival, microcolony survival assay was done according to Withers an (l Elkind's method. To analysis apoptosis, TUNEL assay was done according to Labet-Moleur's method. RESULTS: Radiation protection effect of melatonin was demonstrated by crypt survival assay and its effect was stronger in high radiation dose area. Apoptosis index with 8 Gy irradiation was 18.4% in control group and 16.5% in melatonin treated group. After 18 Gy, apoptosis index was 17.2% in control group and 15.4% in melatonin treated group. Apoptosis index did not show statistically significant difference between melatonin treated group and control group. CONCLUSION: Melatonin shows clear protective effect in mouse jejunum against radiation damage but it.', protective effect seems not to be related with apoptosis protection effect.
Animals
;
Apoptosis*
;
Cell Survival*
;
In Situ Nick-End Labeling
;
Jejunum
;
Melatonin*
;
Mice*
;
Radiation Protection