No abstract available.
Growth Disorders* ; Insulin-Like Growth Factor Binding Proteins* ; Somatomedins*

No abstract available.
Adrenal Hyperplasia, Congenital* ; Korea*

Following is the result of a survey hold over a two year period(1971-1972), on the appearence and disappearence of ticks on cattle in Cheju. Number of Haemaphysalis longicornis. Larvae: From the beginning of July to mid September larvae abounded reaching their peak during July and August. In 1971 their period was from July to September. In 1972 their period was from May to October. In both years their number reached their highest point in July and August(Table 1.2) Nymph: Ticks were found from February to October(1971) and January to December (1972), and they were especially plentiful during the periods of may (1971)(Table 1.2). Adult : Ticks were in evidence from April to October(1971) and January to December(1972). They were especially plentiful during the periods of July and August(1971) and August(1972). However, in 1972 they were also quite plentiful in June and July(1972)(Table 1.2). Percentage of Haemaphysalis longicornis. 1971(Fig. 1): February-May: nymph 94.1 percent, adult female 5.9 percent ; July-August: larvae 54.8 percent, 1972(Fig. 2) : January-May: larvae 18.2 percent, nymph 18.2 percent, adult female 3.8 percent; July-August: larvae 48.2 percent, nymph 11.6 percent, adult female 40.2 percent. Number of Boophilus microplus: larvae; Ticks were in evidence from April to October(1971) and January to December(1972). They were especially plentiful during the periods of June adn July(1971) and July to August(1972). However, in 1972 they were also quite plentiful in May. Nymph: Ticks were in evidence from January to December 1971 and 1972. They were especially plentiful during the periods of June and August(1971) and May to September(1972). However, in 1972 they were also quite plentiful in October and November. Adult: Ticks were in evidence from January to December 1971 and 1972. They were especially plentiful during the periods of July to September(1971) and July (1972). However, in 1972 they were also quite plentiful in May to August. Percentage of Boophilus microplus. 1971(Fig. 3): January-May: larvae 40.3 percent, nymph 32.3 percent, adult female 27.1 percent, July-August: larvae 31.2 percent , nymph 35.7 percent, adult female 33.5 percent. 1972(Fig. 4): January-May: larvae 32.8 percent , nymph 42.1 percent, adult female 25.1 percent, July-August: larvae 44.2 percent, nymph 26.4 percent, adult female 29.4 percent.
parasitology-arthropoda-tick ; Haemaphysalis longicornis ; Boophilus microplus ; biology

No abstract available.

No abstract available.
Hyperthyroidism*

Nesidioblastosis, also known as persistent hyperinsulinemic hypoglycemia of infancy(PHHI) or familial hyperinsulinsm, is the most common cause of recurrent severe hypoglycemia in infancy. It is an autosomal recessive disorder characterized by irregular insulin secretion leading to inappropriately raised plasma insulin concentration compared to blood glucose levels. Recently, mutations in the sulfonylurea receptor(SUR) have been described in association with PHHI. The mainstay of medical treatment is glucose infusion and diazoxide or long acting somatostatin. If medical treatment fails in preventing hypoglycemia, near total pancreatectomy is recommended. We report one case of nesidioblastosis cured by near total pancreatectomy with brief review of literatures.
Blood Glucose ; Congenital Hyperinsulinism* ; Diazoxide ; Glucose ; Humans ; Hypoglycemia ; Infant, Newborn* ; Insulin ; Nesidioblastosis* ; Pancreatectomy ; Plasma ; Somatostatin

Clinical characteristics and growth pattern were evaluated in 42 patients with classical congenital adrenal hyperplasia treated since diagnosis. And final height was evaluated in 16 patients who had reached final adult height with regard to clincal form, degree of hormonal control, and age of initial treatment. The results were as follows; 1) Among 42 patients with classical congenital adrenal hyperplasia, the male to female sex ratio was 1:1.8 (15 males and 27 females), and the frequency of the salt-wasting form (SW) and simple virilizing form (SV) was same (21 SW and 21 SV). 2) The length of time to initial treatment averated 4.2 months (range: 9 days-49 months) for salt-wasting form and 8.8 years (range: 1 month-21 years) for simple virilizing form. 3) In seven cases, precocious puberty developed during treatment and the average age on development was 6.8 years for salt-wasting form and 5.4 years for simple virilzing form. 4) The pattern of growth from birth throughout childhood in salt-wasting patients showed poor growth initially. The average height in simple virilizing patients was above the mean in the first years of life, declining steadily (falling below the mean by age 12), until the end of the growt period. 5) Bone ages were retarded initially in salt-wasting patients, thereafter accelerating by age 3, meanwhile in simple virilizing patients advanced initially. 6) In 16 patients who had reached final adult height, analysis of final height with regard to clinical form, degree of hormonal control, and age of initial treatment indicated that neither of them seem to after the height outcome. In conclusion, classical congenital adrenal hyperplasia patients seem to achieve final height consistently below the mean for the general population. Factors to affect the height outcome (clinical form, degree of hormonal control, age of initial treatment) may influence concomitently, and another factor may be present.
Adrenal Hyperplasia, Congenital* ; Adult ; Diagnosis ; Female ; Humans ; Male ; Parturition ; Puberty, Precocious ; Sex Ratio

Statistical observation was made on the 1949 patients with cardiovascular diseases who had been treated in Dept. of Internal Medicine, Seoul national University Hospital during the period of four years, from jan. 1972 to Dec. 1975. 1) The patients wth cardiovascular diseases accounted for 20.2% out of total 9,638 medical inpatients. The incidence for the consecutive years was not apparently variable. 2) The diseases occured most frequently in the sixth decades and the incidence decreased in the order of fifth and seventh decades. 3) The disease was more prevalent in male than female with ratio of 1.3 of 1. 4) The hypertension was the most common disease among cardiovascular diseases, accounting for 67.5% of patients with cardiovascular diseases and 13.6% of total medical inpatients. The disease occurred most frequently in the sixth decades and the incidence decreased in the order of fifth and seventh decades with male preponderance. 81.8% of patients with hypertension was essential hypertension and 18.2% was secondary hypertension. Secondary hypertension was caused by parenchylmal renal diseases in most patients and there were only several patients with renovascular and endocrine hypertension. 40.2% of patients with essential hypertension had no complications, 38.6% had cerebral vascular accidents, 12.1% had uremia and 9.1% had congestive heart failure. The patients with malignant hypertension was 9.6% of total patients with hypertension. 5) Rheumatic heart disease was 14% of patients with cardiovascular diseases, being second in incidence. It was more prevalent in female than male with ratio of 1 male to 1.3 female and affected the mitral valve in most of the cases, whereas involvement of aortic valve was rare. 6) The coronary heart disease was 5.3% of patients with cardiovascular diseases, being third in incidence. It occured most frequently in seventh and sixth decades and affected male two times more frquently than female. 7) The congenital heart disease was 2.9% of patients with cardiovascular diseases, of which atrial septal defect was highest in incidence. 8) The cor-pulmonale was 1.4%, pericarditis 1.4%, endocarditis 0.9%, postpartum heart disease 1.2%, myxedematous heart disease 0.2%, arrhythmia 2.1%, peripheral vascular disease 1.1% and miscellaneous 0.6% of patients with cardiovascular diseases. 9) Postpartum heart failure and endocarditis was remarkably decreased in incidence recently and there were one patients with beriberi heart disease and one patient with syphilitic heart disease during those years of this study.
Aortic Valve ; Arrhythmias, Cardiac ; Beriberi ; Cardiovascular Diseases* ; Coronary Disease ; Endocarditis ; Female ; Heart Defects, Congenital ; Heart Diseases ; Heart Failure ; Heart Septal Defects, Atrial ; Humans ; Hypertension ; Hypertension, Malignant ; Incidence ; Inpatients ; Internal Medicine ; Korea* ; Male ; Mitral Valve ; Pericarditis ; Peripheral Vascular Diseases ; Postpartum Period ; Rheumatic Heart Disease ; Seoul ; Uremia

5 alpha-reductase deficiency resulting in male pseudohermaphroditism is a rare disease characterized by clitoral-like phallus, bifid scrotum, urogenital sinus, testis cited in labioscrotal folds. Evaluation of plasma T/DHT ratios in infancy, particularly after hCG stimulation of the testes and elevated urinary tetrahydrocortisol (THF) to 5 alpha-tetrahydrocortisol(5 alpha-THF) ratios provide a valuable dianostic test for 5 alpha-reductase deficiency. We report one case of 5 alpha-reductase deficiency who were presented with ambiguous genitalia and elevated T/DHT ratio before and after hCG stimulation.
46, XY Disorders of Sex Development ; Cholestenone 5 alpha-Reductase* ; Disorders of Sex Development ; Plasma ; Rare Diseases ; Scrotum ; Testis ; Tetrahydrocortisol

No abstract available.
Anemia, Iron-Deficiency* ; Hypoproteinemia* ; Iron*