We report a case of embryonal rhabdomyosarcoma with palpable right inguinal lymph node in a 6-year-old girl which developed rapidly on the right labia minora over a period of 2 montha. Histopathological study showed characteristic findings of spindle shaped rhabdomyoblast with hyperchromatic nuclei and cytoplasmicprocesses. After a preoperative chemotherapy with vincristine, actinomycin D, and cytoxan, the size of the mass was reduced, and lymph nodes were not palpable. And then, simple vulvectomy. postoperhtive cheirnatherapy and radiotherapy were done.
Child ; Cyclophosphamide ; Dactinomycin ; Drug Therapy ; Female ; Female* ; Genitalia, Female* ; Humans ; Lymph Nodes ; Radiotherapy ; Rhabdomyosarcoma, Embryonal* ; Vincristine

The cause of premature ejaculation (PE) has been thought to be psychological in the majority of patients but we investigated penile hypersensitivity for an organic basis of PE. For another organic basis of PE, we have suggested hyperexcitability of the ejaculation center. SS-cream is a topical agent containing 9 oriental herbs for treating PE. Clinically SS-cream has been effective in the treatment of PE. Therefore, in order to implicate the organic basis of PE and realize the effect of SS-cream on PE, we investigated the somatosensory evoked potential (SEP) in patients with PE(16 cases) and the effects of SS-cream on SEP for treating PE. The latencies and amplitudes of the evoked responses were measured by two different places in stimuli, one was on the penile shaft with ring electrode and the other on the glans penis with a surface electrode. The latency of SEP stimulated at the glans penis was significantly longer than that stimulated at the penile shaft (p< 0.05). The latency stimulated at the glans penis after applying SS-cream was significantly longer than before applying SS-cream (p< 0.05), which was near the level of a normal potent man. But the latency stimulated at the penile shaft has no significant difference between before and after the application of SS-cream (P > 0.05). The amplitudes of the evoked responses stimulated at the glans penis were significantly higher than those stimulated at penile shaft (p< 0.05). And both these amplitudes were significantly reduced with the application of SS-cream (p< 0.05). With these result, we can suggest that the patients with PE have glans penile hyperexcitability and it provides further implications for an organic basis of PE, SEP stimulated at the glans penis can be a very useful method to evaluate PE, along with SEP stimulated a penile shaft and SS-cream prolongs the sensory conduction and reduces the penile hyperexcitability of the patient with PE.
Adult ; Drugs, Chinese Herbal/*therapeutic use ; Ejaculation/*drug effects ; Evoked Potentials, Somatosensory/*drug effects ; Human ; Male ; Middle Age ; Sexual Dysfunctions, Psychological/*drug therapy/physiopathology

Serum specimens from leprosy patients, their contacts and controls were examined for the presence of phenolic glycolipid I (PGL-I), a Mycobacterium leprae specific antigen, and antibodies to the antigen using enzyme-linked immunosorbent assays. Of 12 lepromatous patients with less than 2 years of therapy, 11(91.7%) were seropositive to PGL-l, thus indicating that new lepromatous cases can be identified by detecting anti-PGL-l antibodies. In contrast 88(56.4%) of 156 lepromatous patiens treated more than 2 years were positve. Moreover, only 69(40.8%) were seropositve among 169 lepromatous patients in the leprosy resettlement villages. The mean antibody level also declined significantly in proportion to the duration of chemotherapy. This may suggest the possibility of monitoring chemotherapy by detecting anti-PGL-l antibodies. The prevalence of anti-PGL-l antibodies among 200 controls from a high endemic area for leprosy was 5.5% and was significantly higher than that(1.5%) among 200 controls from a low endemic area. Of 103 household contacts in the resettlement villages, 10(9.7%) were seropositive, reflecting the frequent chance of exposure to M. leprae. However, PGL-l was not detected many in any of the sera from controls, contacts, and inactive lepromatous patients having the anti-PGL-l antibodies; on the other hand, 6(50%) of 12 lepromatous patients treated less than 2 years had detectable PGL-l in their sera. The results thus indicate that PGL-l detection may be more suitable for monitoring the effectiveness of chemotherapy and that it may be necessary to examine for the presence of PGL-l in sera from contacts and normal populations for confirming M. leprae infection.
Antibodies, Bacterial/*analysis ; Glycolipids/*blood ; Human ; Leprosy/*blood/diagnosis ; Serologic Tests ; Support, Non-U.S. Gov't

The previous reports have indicated that both the DMSA scan and the DTPA scan were significantly related with the relative renal function ( RRF) and there was a close relationship between the DMSA scan and the DTPA scan in the evaluation of the RRF We reviewed our experience with 24 cases, in which the DMSA scan and the DTPA scan were performed within 2 weeks from January 1987 to April 1991. The DMSA scan was more reliable than the DTPA scan and the difference of the RRF between right and left side by the DMSA scan was more apparent than that by the DTPA scan. However, in infants, both scans showed the reversed results. Our study suggests that DMSA scan is more reliable than the DTPA scan in the evaluation of the RRF, but both renal scans are inappropriate in infants, especially under the age of 1 months.
Humans ; Hydronephrosis* ; Infant ; Pentetic Acid* ; Succimer*

Two 4-day-old Thoroughbred foals with acute clinical signs of depression, elevated pulse and respiratory rates, anemia, and jaundice were referred to the equine hospital of Korea Racing Authority. The foals were seemingly normal at birth, but showed clinical signs such as abnormal behavior, jaundice and anemia suddenly after ingestion of the mare's colostrum, followed by death at 4 days after birth. According to the results of the hematology, serum chemistry analysis, jaundice foal agglutination test, and blood groups test, the foals were diagnosed as neonatal isoerythrolysis (NI) caused by the mare's antibodies. These results suggested that the pregnant mares have a potential for NI.
Agglutination Tests ; Anemia ; Antibodies ; Blood Group Antigens ; Colostrum ; Continental Population Groups ; Depression ; Eating ; Hematology ; Humans ; Jaundice ; Korea ; Parturition ; Respiratory Rate

From January 1986 to December 1990, preliminary percutaneous nephrostomy (PCN) was performed on 16 children for hydronephrosis. Infection was the most frequent presenting feature. This procedure was useful for providing drainage of pyonephrotic kidneys, for accessing recovery of renal function after relief of obstruction, and for preserving or regaining renal function in patients who were not fit for major surgery. Complications were uncommon and usually minor. Our experience has encouraged us to accept this procedure, both diagnostically and therapeutically. And we believe that it is safe, easily performed and effective and has become a valuable non-surgical alternative that should be favorable to manage children, especially infants, with urinary tract obstruction.
Child ; Drainage ; Humans ; Hydronephrosis* ; Infant ; Kidney ; Nephrostomy, Percutaneous* ; Urinary Tract

To confirm the effect of SS-cream, which was based on the traditional Chinese Royal herb remedy including 8 oriental herb combinations, 43 out of 150 patients with premature ejaculation (PE) were selected and investigated for a double-blind clinical trial between Nov. 1993 and Feb. l994. There mean age was 41.4 years. The 28 patients complained of PE only but 15 had concurrent mild psychogenic impotence. Only 20% of their spouse was satisfied for sexual lives. The packages of SS-cream and controls such as 1.25% (LL), 5%(ML) and 10%(HL) lidocaine cream were made similarly as much as 0.2g. They were randomly divided into the 5 groups. Each patient was assigned to apply LL, ML or SS cream once a weak for 4 consecutive weeks as scheduled. A within subjects comparison of pre and post application for ejaculation time and spouse's satisfaction was investigated. The applied groups such as LL, ML and HL cream were not effective. After SS-cream application, ejaculation time was delayed upto mean 11.3min. in 40(93%) and most of them with PE only as well as PE associated with impotence were satisfied. These data suggest that SS-cream is effective in treating PE as well as PE with mild impotence.
Asian Continental Ancestry Group ; Ejaculation ; Erectile Dysfunction ; Humans ; Lidocaine ; Male ; Premature Ejaculation* ; Spouses

No abstract available.
Mucocele*

BACKGROUND: The use of choledochoscopy has been increasing lately in open and laparoscopic surgery for bile duct stones. Intraoperative choledochoscopy is useful for assessing the biliary trees and stones and for assisting in the removal of bile duct stones. However, large or impacted bile duct stones are difficult to remove using choledochoscopy alone. Application of electrohydraulic lithotripsy (EHL) seems to be suited for these difficult cases. METHODS: Twenty-six (26) patients with bile duct stones were treated with intraoperative cho ledochoscopic EHL to remove stones which could not be retrieved using stone forceps, a basket, saline flushing, or a Fogarty catheter. We divided the 26 cases into two groups: 12 cases of laparoscopic surgery and 14 cases of open surgery. These cases were further divided into two groups: common bile duct stones and intrahepatic duct stones RESULTS: The indications of EHL in laparoscopic surgery for common bile duct stones were large stones in 2 cases and impacted stones in 4 cases. Eighteen (18) patients with intrahepatic duct stones were treated with EHL for impacted stones. Stone clearence rate was 88.5%, and complications occurred in 3 cases (11.5%). One case of a biliary fistula was managed conservatively, and two cases of mucosal bleeding of the bile duct were spontaneously controlled. CONCLUSION: Intraoperative choledochoscopic electrohydraulic lithotripsy is a safe and effective method for removing large or impacted bile duct stones.
Bile Ducts* ; Bile* ; Biliary Fistula ; Catheters ; Common Bile Duct ; Flushing ; Hemorrhage ; Humans ; Laparoscopy ; Lithotripsy* ; Surgical Instruments

PURPOSE: Torus palatinus is a bony prominence at the middle of the hard palate. The size varies from barely discernible to very large, from flat to lobular. This oral exostosis is not a disease or a sign of disease, but if large, may be a problem. So, we present the clinical and histopathologic features and applied therapy and provide a comprehensive review of the rare case of the symptomatic exostoses. METHODS: A 37-year-old woman had slowly growing exophytic nodular mass of the bone that arises the midline suture of the hard palate. The patient was concerned about discomfort associated with movement of her tongue and about frequent irritation of the palatal mucosa during mastification of the hard food. The patient had a large, unilobulated torus palatinus. It extended from the area adjacent to the canine to a point beyond the junction with the soft palate. The mass was oblong in shape, measuring about 3cm long, 2cm wide, and 0.8cm in height. RESULTS: Before surgical intervention a CT was obtained for the sake of estimating the thickness of the bone between the exostoses and the maxillary antrum and floor of the nose. The surgical procedure was performed with the patient under general anesthesia. Removal of the exostosis was performed after midline mucoperiosteal incision with osteotome and diamond burr. Histologic finding revealed decalcified dense bony tissue, the presence of lacunae, and normal osteocytes. CONCLUSION: Surgical removal is recommended when one or more of the following condition exist: interference with the construction of prosthesis, interference with oral function, irritation or pathology of the overlying tissue, inability of the patient to maintain proper oral hygiene, and fear of malignancy or other psychologic trauma. We report a rare case of the torus arising in hard palate with symptoms.
Adult ; Anesthesia, General ; Diamond ; Exostoses ; Female ; Floors and Floorcoverings ; Humans ; Hyperostosis ; Maxillary Sinus ; Mucous Membrane ; Nose ; Oral Hygiene ; Osteocytes ; Palate ; Palate, Hard ; Palate, Soft ; Prostheses and Implants ; Sutures ; Tongue