1.A Case of Lofgren' s Syndrome.
Seong Gyu YANG ; Dae Hun SUH ; Kwang Hyun CHO
Korean Journal of Dermatology 1995;33(5):931-934
Sarcoidosis is a rare d:sease in Korea and its association with erythema nodosurn is even rarer. Recently we saw a patient of bihilar adenopathy, who had arthralgia and erythematous nodules of both lower legs. A skin biopsy obtained from the erythematous nodule of the lower leg showed septal panniculitis, consitent with erythema nodosum, and a biopsy from the mediastinal lymph node revealed a pathology consistent with sarcoidosis. This is the first case of Lofgrens syndrome confirmed by histology ir, Korea.
Arthralgia
;
Biopsy
;
Erythema
;
Erythema Nodosum
;
Humans
;
Korea
;
Leg
;
Lymph Nodes
;
Panniculitis
;
Pathology
;
Sarcoidosis
;
Skin
2.A Case of Sturge-Weber Syndrome.
Jin Soo JO ; Moon Chung CHAO ; Doo Seong MOON ; Kyung Sook CHO ; Chong Dae CHO
Journal of the Korean Pediatric Society 1986;29(4):103-108
No abstract available.
Sturge-Weber Syndrome*
3.A Case of Thanatophoric Dwarfism.
Young Kyun HWANG ; Soo Baeck MOON ; Chong Dae CHO ; Ju Kyeong LEE ; Doo Seong MOON
Journal of the Korean Pediatric Society 1983;26(11):1129-1132
No abstract available.
Thanatophoric Dysplasia*
4.Infantile Fibrosarcoma in Neonate.
So Hyun NAM ; Min Jung CHO ; Dae Yeon KIM ; Seong Chul KIM ; In Koo KIM
Journal of the Korean Surgical Society 2010;79(Suppl 1):S62-S66
Infantile fibrosarcoma is a rare malignant soft tissue tumor occurring especially in newborn and young children under 2 years. We experienced three cases of infantile fibrosarcoma presenting in the neonatal period. Case 1 presented with a multiseptated cystic mass on his left thigh at birth that was diagnosed as lymphangioma. After picibanil injection, we noted the size of the mass doubled and a solid lesion was prominent in the magnetic resonance image. Case 2 was found to have a reddish mass on his lower back mimicking hemangioma. Over 2 weeks, the mass grew rapidly with internal hemorrhaging. Case 3 was noted to have an encircling mass around the splenic flexure, which developed into congenital bowel obstruction. All of the tumors were resected completely, but microscopic resection margin was not clear in two patients. The two patients received adjuvant chemotherapy and all patients are well without evidence of recurrence.
Chemotherapy, Adjuvant
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Child
;
Colon, Transverse
;
Fibrosarcoma
;
Hemangioma
;
Humans
;
Infant, Newborn
;
Lymphangioma
;
Magnetic Resonance Spectroscopy
;
Parturition
;
Picibanil
;
Recurrence
;
Thigh
5.Imaging Findings of Intragastric Gallstone and Bouveret's Syndrome.
Seong Youb LIM ; Hun SEONG ; Jong Yeon PARK ; Chang Hye SEO ; Kyung Jae JANG ; Seong Rak CHO
Journal of the Korean Radiological Society 2000;42(1):133-136
Gallstone ileus is a well-known complication of cholelithiasis, but is relatively rare. Most ectopic gallstones are located in the small bowel; they are rarely found in the stomach and duodenum. We describe the imaging findings of a case of intragastric gallstone, as well as a case in which duodenal obstruction was caused by a large gallstone (Bouveret's syndrome).
Cholelithiasis
;
Duodenal Obstruction
;
Duodenum
;
Gallstones*
;
Ileus
;
Stomach
6.Leiomyoma of the Appendix: A Case Report.
Seong Hoon KIM ; Hyun Cheol CHO ; Mi Young SON
Journal of the Korean Radiological Society 2007;56(5):487-489
Leiomyomas of the appendix are rare and most are encountered incidentally during exploration of the abdomen for some other disease, during postmortem examination, or in the course of routine pathologic examinations of surgical specimens. We report here the findings of ultrasonography, CT and surgery of a case of leiomyoma that arose from the appendix; this lesion was pathologically confirmed.
Abdomen
;
Appendix*
;
Autopsy
;
Leiomyoma*
;
Ultrasonography
7.Emerging Endotypes of Chronic Rhinosinusitis and Its Application to Precision Medicine.
Allergy, Asthma & Immunology Research 2017;9(4):299-306
Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory disease with various underlying pathophysiologic mechanisms which translate to endotypes, in contrast to clinical phenotypes or histological subtypes. Defining endotypes can help clinicians predict disease prognosis, select subjects suitable for a specific therapy, and assess risks for comorbid conditions, including asthma. Therefore, with recent advancement of biologicals in CRS clinical trials, endotyping can be a breakthrough in treating recalcitrant CRS. CRS is caused by dysregulated immunologic responses to external stimuli, which induce various inflammatory mediators from inflammatory cells, including innate lymphoid cells (ILCs) and T lymphocytes as well as epithelial cells. Thymic stromal lymphopoietin (TSLP), interleukin (IL)-25, and IL-33, which are mainly secreted by epithelial cells in response to external stimuli, act on type 2 ILCs and T helper 2 (Th2) cells, inducing IL-4, IL-5, and IL-13. Local immunoglobulin E (IgE) production is also a signature event in nasal polyps (NP). These inflammatory mediators are novel potential therapeutic targets for recalcitrant CRS. This article reviews recent publications regarding endotypes and endotype-based therapeutic strategies in CRS and NP.
Asthma
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Cytokines
;
Epithelial Cells
;
Immunoglobulin E
;
Immunoglobulins
;
Interleukin-13
;
Interleukin-33
;
Interleukin-4
;
Interleukin-5
;
Interleukins
;
Lymphocytes
;
Nasal Polyps
;
Phenotype
;
Precision Medicine*
;
Prognosis
;
T-Lymphocytes
8.Dynamic CT Findings of Eosinophilic Hepatic Abscess and Its Clinical Course.
Dae Hyoun CHO ; Jae Chun CHANG ; Ki Ho SEONG
Journal of the Korean Radiological Society 1996;35(6):899-904
PURPOSE: To evaluate dynamic CT features and its clinical courses of eosinophilic hepatic abscess. MATERIALS AND METHODS: Two-phase dynamic CT findings and the clinical courses of 13 pathologically proven cases of eosinophilic abscess were reviewed. All patients showed peripheral eosinophilia, and diagnoses were confirmed by ultrasound-guided biopsy(n=9) or operation(n=4). In two of the four patients who underwent segmental hepatectomy, worms of the species Fasciola hepatica were detected. Follow-up CT scans after treatment with antibiotics or praziquantel were available in seven and eight patients, respectively. RESULT: All hepatic lesions were found ina subcapsular location or in contact with Glisson's capsule around the bile duct. Arterial-dominant phase CT(n=11)demonstrated clusters of ill-defined low density masses without rim enhancement. Late-phase CT(n=13) more clearly depicted clustering lesions with enhancing rims and diminution of the low-density area. Follow-up CT scans aftertreatment with antibiotics(n=7) showed no change in the lesions in three patients and slight shrinkage of the mainmass with additional new lesions in four. On CT scans of nine patients performad after praziquantel therapy, hepatic masses were seen in all patients to be very slightly smaller after improvement of peripheral hypereosinophilia. CONCLUSION: Two-phase dynamic CT features appear to be helpful for the diagnosis ofeosinophilic hepatic abscess in patients with peripheral eosinophilia. Parasitic infestation by Fasciola hepaticafor example, is the presumed cause of such abscesses, though further studies are required.
Abscess
;
Anti-Bacterial Agents
;
Bile Ducts
;
Diagnosis
;
Eosinophilia
;
Eosinophils*
;
Fasciola
;
Fasciola hepatica
;
Follow-Up Studies
;
Humans
;
Liver Abscess*
;
Parasites
;
Praziquantel
;
Tomography, X-Ray Computed
9.Protective Effects of the NMDA-receptor Antagonist (MK-801) for the Brain Injury by Oxygen Free Radical: In the Hyperbaric Oxygen Treatment of CO Poisoned Rat.
Dae Eun JUNG ; Seung Ho RYU ; Jin A CHO ; Jae Cheol SONG ; Hung Bae PARK
Korean Journal of Occupational and Environmental Medicine 1997;9(1):40-48
The effects of NMDA-receptor antagonist (MK-801) were assessed for the oxygen free radical mediated brain (hippocampus) injury with eighty rats which were exposed to carbon monoxide (CO) followed by hyperbaric oxygen (HBO) treatment. Superoxide dismutase (SOD) and malondialdehyde (MDA) were used as parameters of the oxygen free radical reaction. Experimental groups consisted of (1) control group (=breathing with air), (2) CO group (=exposed to CO after air breath), (3) CO-air group(exposed to CO after air breath followed by air breath), and (4) CO-HBO group (=exposed to CO after air breath followed by 3 ATA HBO). Each group was divided two subgroup according to the pretreatment (normal saline or MK-801). CO, CO-air and HBO groups increased in SOD activity as compared with control group. And CO-air and HBO groups increased in MDA as compared with control and CO group. Pretreatment of MK-801 decreased SOD activities significantly (p-value<.05) , but MDA amount not significantly (p-value=.107). These results suggest a useful protective effect of NMDA-receptor antagonist (MK-801) in CO induced hippocampal injury mediated by oxygen free radicals.
Animals
;
Brain Injuries*
;
Brain*
;
Carbon Monoxide
;
Dizocilpine Maleate
;
Free Radicals
;
Malondialdehyde
;
Oxygen*
;
Rats*
;
Superoxide Dismutase
10.A Case of Sirenomelia.
Moon Chung CHAO ; Sae Jin LEE ; Jin Soo JO ; Hyun Sook KIM ; Doon Seong MOON ; Chong Dae CHO
Journal of the Korean Pediatric Society 1986;29(3):100-103
No abstract available.
Ectromelia*