No abstract available.
Fistula* ; Humans ; Infant*

Two cases of exercise-induced atrial fibrillation were diagnosed in 68 years old female and 47 years old male. They complained palpitation during exercise, and emotional upset for the last 5 years. There was no evidence of organic heart disease except mild hypertension in female patient. The atrial fibrillation was induced repeatedly by treadmill exercise test and intravenous infusion of isoproterenol. The beta blocker(atenolol 50mg po dialy) prevented the induction of atrial fibrillation during treadmill exercise. We report two cases of exercise-induced atrial fibrillation which is very rare and might be related to catecholamine.
Aged ; Atrial Fibrillation* ; Exercise Test ; Female ; Heart Diseases ; Humans ; Hypertension ; Infusions, Intravenous ; Isoproterenol ; Male ; Middle Aged

To assess the likelihood of procedural success in patients with multivessel coronary artery disease, 46 consecutive patients (male 34, female 12, mean age 60+/-9 years) umderwent single or multiple site angioplasty. The clinical diagnosis of unstable angina was in 20(44%), stable angina in 10 and acute or old myocardial infarction in 16. Coronary angiographic findings of 2 vessel disease was in 38(83%), triple vessel disease in 8. Left ventricular function was generally well preserved (mean ejection fraction 65+/-12%, range 30-82%) and mean 2.0 stenosis per patient angic, lasty had attempted. Single vessel angioplasty (SVA) was performed in 13 and multivessel angioplasty (MVA) in 33. Procedural success was achieved in 79(86%) out of total 92 stenoses. Sixty-six(88%) out of 75 stenoses in MVA and 13(76%) out of 17 stenoses in SVA had procedural success respectively. According to angiographic morphology of lesions, procedural success of type A stenoses was 17/17(100%), type B stenoses 57/66(86%) and type C stenoses was 5/9(33%). In 13 failures included inability to pass the guide wire cross the lesion in 7, inability to guide the griding catheter in 2 and inability to dilate lesions in 4. Before and after angioplasty, treadmill test (modified Bruce protocol)could be performed in 29 patients. Total duration of exercise and maximal double product improved significantly from 8.5+/-2.3 minute 5188+/-2403 to 12.2+1.3 min., 23,062+/-4111 respectively (p<0.001). 17 out of 24 patients who had positive treadmill test before angioplasty showed negative conversion after procedure. Complications included dissection in 29, prolongd chest pain in 5, acute closure in 3, cardiac tamponade in 1 and ventricular fibrillation due to side branch oclusion in 1. Thus, coronary angioplasty in selected paients with multivessel coronary artery disease might be useful and have relatively good immediate results, but the long-term efficacies with other forms of treatment must be evaluated prospectively.
Angina, Stable ; Angina, Unstable ; Angioplasty* ; Cardiac Tamponade ; Catheters ; Chest Pain ; Constriction, Pathologic ; Coronary Artery Disease* ; Coronary Vessels* ; Diagnosis ; Exercise Test ; Female ; Humans ; Myocardial Infarction ; Ventricular Fibrillation ; Ventricular Function, Left

PURPOSE: Non-enhanced spiral computed tomography (NESCT) has become the preferred method for imaging urinary calculi. We evaluated the Hounsfield units (HU) of urinary calculi on NESCT as a predictor of the therapeutic effect of extracorporeal shockwave lithotripsy (ESWL). MATERIALS AND METHODS: We evaluated 72 patients with urinary calculi who underwent ESWL. The HUs of calculi were measured on the pretreatment NESCT and at post-treatment via radiographic assessment. The patients were divided into 2 groups, the response group (n=39): the patients with remnant calculi less than 3mm or they were without remnant calculi, and the non-response group (n=33): the patients with remnant calculi greater than 3mm. The HUs of the response and non-response groups were then compared. RESULTS: The HUs of the response and non-response groups were 529.7+/-168.2 and 814+/-116.6, respectively, and the HUs of the non-response group was significantly higher than that of the non-response group. CONCLUSIONS: The HU of urinary calculi, as seen on NESCT, can help to predict the therapeutic effect of ESWL and also select the most effective treatment modalities for the patients suffering with urinary calculi.
Calculi ; Humans ; Lithotripsy* ; Tomography, Spiral Computed ; Urinary Calculi*

BACKGROUND: More than 200 million people suffer from malaria worldwide. In Korea this infectious disease had been on a decreasing trend since 1930s and was considered to be eradicated from 1985. However, since 1993 when a case of malaria was reported, its incidence is progressively increased. Recent efforts have been focused on the development of vaccine against the infective sporozoite stage of Plasmodium vivax. It has been found that sporozoites are complicated with genetic variation within the circumsporozoite gene and phenotypic heterogeneity in the protein it encodes. So, we investigated the distribution of circumsporozoite gene of Plasmodium vivax in Korea. METHODS: Polymerase chain reactions (PCR) were performed on samples confirmed with microscopic examination for P. vivax and negative samples with clinical and microscopic examination. The amplified products were analyzed by dot hybridization with oligonucleotide probes VK210 and VK247 which are respectively complementary to the predominant and variant strains of the circumsporozoite gene of P. vivax. RESULTS: The incidence of isolation in VK210 and VK247 strains were 96.3%, respectively and individuals who were infected with both strains were 92.7%. Compared to the microscopic examination, the results of PCR showed 82% in sensitivity, 100% in specificity. CONCLUSIONS: The present study suggests that a single-epitope vaccine based on either one circumsporozoite domain is unlikely to be protective because both VK210 and VK247 strains of P. vivax were found widely in Korea. The PCR method appears not to be feasible as a screening, but suitable as a confirmatory test for the identification of Plasmodium species.
Communicable Diseases ; Genetic Variation ; Genotype* ; Incidence ; Korea* ; Malaria ; Mass Screening ; Oligonucleotide Probes ; Plasmodium vivax* ; Plasmodium* ; Polymerase Chain Reaction ; Population Characteristics ; Sensitivity and Specificity ; Sporozoites

There are several methods for diagnosis of leprosy, including AFB stain, the measurement of PGL-1 (phenolic glycolipid - 1) antigen titer, and DNA-PCR. In this study, we have used the DNA-PCR amplifying the RLEP repetitive sequence. Our result showed that the RLEP primer offered the more sensitive detection and identification of M. leprae DNA in clinical specimens, compared with the other primer, for example, 18-kDa antigen gene. To screen the resistant M. leprae strain of MDT (Multi-Drug Therapy), we have used the TD (Touch-Down) PCR. We arranged and amplified sequences of the genes, folP, rpoB, gyr, 23S rRNA, in M. leprae involved in MDT-resistance, and could obtain the PCR product each gene, simultaneously. This method, based on annealing temperature, was useful to the detection for diagnosis and the screen of MDT-resistant strain of M. leprae, rapidly. Thus, we suggest that the RLEP primer and TD-PCR method are effective in assessing the diagnosis of leprosy and the identification of drug-resistant M. leprae.
Diagnosis* ; DNA ; Leprosy* ; Polymerase Chain Reaction* ; Repetitive Sequences, Nucleic Acid

Various methods of taking of optic foramen view and avalubilities have been studied by many foreigninvistigators, but those in Korea have not been reported yet. The authors have measured and examined the size andshapes of optic foramina of optic foramen views in 111 Korean checked at Inje Medical College Hospital duringabout 3 years form June 1979 to March 1982. The cases were divided into gwo groups, A and B, for the convenienceof study. Group A consisted of 50 normal Korean 5 to 55 years of age with no visual symptoms and signs. Group Bincluded 69 patients 3 to 75 yrs of age with visual symptoms and signs. The results were as follows; 1. Mean valueof actual diameter of optic foramen meassured by Goalwin's method in Group A; Right; A diameter; 4.21mm, Bdiameter; 4.32mm, Left; A diameter; 4.29mm, B diameter; 4.30mm. 2. Absolute symmetry of the greatest diameters ofboth optic foramina in Group A; 36%, difference of 0.5 or lessl 28%, from 0.5 to 1.0mm; 18%, from 1.0 to 1.5mm;8%, uncomparable cases; 10%. The greatest difference was 1.4mm. 3. The shapes of optic foramen in Group A; ovalshape; 65%, circular ; 29%, keyhole or double foramen; 6%. 4. In Goup B, the peak age group was second decade(31%), the most comon clinical cause of examiniation of optic foramen view was optic nerve atrophy(30%), and thepathologic findings were only 4 cases(7%). 5. The technique of optic foramen view by modified Pfeiffer's methoddelineated the outline of optic foramen more clearly than ordinary Rhese's method in our experience.
Humans ; Korea ; Methods ; Optic Nerve

No abstract available.
Humans*

No abstract available.
Fibroma ; Giant Cells ; Granuloma, Giant Cell

No abstract available.
Adenoma, Pleomorphic