No abstract available.
Overbite*

Cerebral aspergillosis is a rare condition that affects primarily the immunocompromised host. Most of cerebral aspergillosis is developed by hematogenous dissemination from extracranial foci, but aspergillosis of sino-nasal origin rarely affects the CNS. In case 1, wel symptom of tumor recurrence was unilateral numbness of the chin. A 65-year-old male was admitted because of paresthesia around the left chin and left lower lip. Neurologic examination revealed hypesthesia on the left side of chin, lower lip and buccal mucous mem-brane. Bone scan (Tc-99m MDP) showed focal hot uptakes on the left mandible and left first rib. Brain CT with bone window setting showed a focal osteolytic lesion in the bone marrow of the left mandibular canal without destruction of bone cortex. Both coronal T1 weighted image and axial T2 weighted image showed focal low signal intensities on the left ramus. The pathophysiologic mechanism could be understood by identification of the pathologic focus.
Aged ; Aspergillosis* ; Bone Marrow ; Brain ; Chin ; Humans ; Hypesthesia ; Immunocompromised Host ; Lip ; Male ; Mandible ; Neurologic Examination ; Paresthesia ; Recurrence ; Ribs

Distributions trends were examined in 9159 malocclusion patients had been examined and diagnosed at Department of Orthodontics, College of Dentistry, Yonsei University over a 6 year-period from 1992 to 1997. The results were as follows: 1. The total number of orthodontic patients in 1997 increased in comparing with that of 1992(86%)and after 1995, the number of annual patients showed an increase. 2. Age distribution had shown over-19 year-old group being the largest(39.9%) but percentages of pre-adolescent patients had been decreasing while that of adult patient had gradually increased. 3. Distributions in the types of malocclusion, the Angle's Classification had shown : 33. 3% for Class I, 28.6% for ClassII and the largest 38.1% for Class III. 4. Among Class I patients, crowding showed the largest(32.6%) and protrusion group had gradually increased to 33.9% in 1996. Otherwise openbite and groups tend to decrease, annually. 5. Geographic distribution showed a majority of patients from Seoul(above 70%). Among the patients from Seoul, group within the distance 3-6km from Yonsei dental hospital was the largest(32.3%) and group within 9km showed 69% of total patients.
Adult ; Age Distribution ; Crowding ; Dentistry* ; Epidemiologic Studies ; Humans ; Malocclusion* ; Open Bite ; Orthodontics* ; Seoul

This stydy was undertaken to evaluate the cephalometric changes of the soft tissue and skeletal profile subsequent to the palatal expansion in 25 Angle's Class III cases, ranging in age from six to fifteen years, with cross-bite of the anterior teeth, underdevelopment of maxilla and facial disharmony. Following results were obtained: 1. ANS moved downward, Point A presented forward & downward movement increasing SNA and point B presented backward & downward movement decreasing SNB. 2. Mandible was rotated to backward & forward and maxilla moved forward & downward with the bite opening and improvement of anterior teeth cross-bite. 3. Soft tissue on inadible was rotated to backward & downward rotation of Point B', Pog'. 4. Respones of the upper lip was more significant in downward than forward direction, and correlated with the upper central incisor and mandible rotation. 5. Reaponse of the lower lip was mord significant in downward than backward direction, and correlated with the mandible rotation. 6. There was a rather high degree of correlation between skeletal porfile and soft-tissue profile, :LS, 1:Pog', Pog:LS, Pog:LI:Pog' in horizontal measurements and 1:Pog', Pog:LI, Pog:Pog' in vertical measurements.
Incisor ; Lip ; Malocclusion* ; Mandible ; Maxilla ; Tooth

Kabuki make-up syndrome (KMS) was firstly reported in 1981 by Niikawa, et al. and Kuroki et al. in a total of ten unrelated Japanese children with characteristic array of multiple congenital anomalies and mental retardation. The name reflects the resemblance between the facial features of patients and the actors of Kabuki, one of the most famous traditional performing arts in Japan. The syndrome is characterized by mental and developmental retardations and peculiar facial features including long palpebral fissures with eversion of the lateral portion of lower eyelid and arching of eyebrows. In addition, dermatoglyphic and skeletal abnormalities are commonly associated. In Japan, the syndrome appears to have an incidence of about 1 : 32,000 newborns. Outside of Japan, a growing number of patients have been recognized. However, this syndrome has been reported only a few cases in Korea. We report a boy diagnosed by clinical features with a brief review of the literature.
Asian Continental Ancestry Group ; Child ; Dermatoglyphics ; Eyebrows ; Eyelids ; Humans ; Incidence ; Infant, Newborn ; Intellectual Disability ; Japan ; Korea ; Male

BACKGROUND: Surgical intervention is known as the principle management for hemoptysis of significant amount But surgical procedure is applicable 13 only small number of patients because of increased mortality in emergency surgery and various functional and structural problems after lung resection. Bronchial artery embolization(BAE) has been used as an alternative interventional technique for immediate control of patients with increased risk for surgery due 19 recurrent or massive hemoptysis. BAE also has limitations such as recurrent bleeding after procedure and its role for the application to small amount of hemoptysis is still not established. METHOD: To evaluate immediate and long term effectiveness of BAE, we analysed 65 patients with hemoptysis according to therapeutic modalities they received ; BAE versus conservative management. RESULTS: The success rate for immediate control of hemoptysis was significantly higher in BAE group with 43 cases(100%) among 43 cases compared with 17 cases(77%) among 22 cases in conservative group (p<0.001). The disease control duration was 19.5α8.06 months in BAE group and 18.8α6.06 months in conservative group(p>0.05). The therapeutic response in BAE group was 82%(36/43 cases) and 95%(21/22 cases) in conservative group(p>0.05). According to the amount of hemoptysis, the therapeutic response were seen in 91%(29/32 cases) in less than 100ml and 85%(28/33 cases) in 100~400ml (p>0.05). According to the manifestation of hemoptysis, the therapeutic response in groups of recurrent and nonrecurent were 87%(20/23 cases) and 88%(37/42 cases)(p>0.05). CONCLUSION: The difference of therapeutic response between BAE and conservative group in patients with small amounts of hemoptysis was not found except for immediate control of hemoptysis.
Bronchial Arteries* ; Emergencies ; Hemoptysis* ; Hemorrhage ; Humans ; Lung ; Mortality

BACKGROUND: A few reports of transudative malignant effusion on a small number of patients have suggested the need to perform routine cytologic examination in all cases of transudative pleural effusion, whether encountered for malignancy or not. The purpose of this study was to investigate whether cytologic examination should be performed in all cases of transudative pleural effusion for the diagnosis of malignancy. METHODS: We performed a retrospective study of 229 consecutive patients with malignant pleural effusion, proven either cytologically or with biopsy. In patients with transudative pleural effusion, we reviewed medical records, results of transthoracic echocardiography, fiberoptic bronchoscopy, chest X-ray, chest CT scan, and ultrasonogram of the abdomen. These data were examined with particular attention to identifying whether or not the malignancy was suggested on chest X-ray, examining the involvement of the superior vena cava, great vessels, and lymph nodes, determining the presence of pericardial effusion, and observing the endobronchial obstruction. RESULTS: Transudative malignant pleural effusion was observed in seven (3.1%) of the 229 patients, and was caused either by the malignancy itself (6 patients) or by coexisting cardiac diseases (1 patient). All the patients showed evidence suggesting the presence of malignancy at the time of initial thoracentesis, which facilitated the decision of most clinicians on whether to perform cytologic examination for the diagnosis of malignancy. CONCLUSION: Therefore, in all cases of transudative pleaural effusion, no clinical implications indicating malignancy were found on cytologic examination.
Biopsy ; Carcinoma/classification/*pathology/*secondary ; Exudates and Transudates ; Human ; Lung Neoplasms/*pathology ; Lymphatic Metastasis ; Neoplasm Staging ; Neoplasms, Unknown Primary/*pathology ; Pleural Effusion, Malignant/metabolism/*pathology ; Retrospective Studies ; Support, Non-U.S. Gov't

STATEMENT OF PROBLEM: Porcelain veneers have become a popular treatment modality for aesthetic anterior prosthesis. Fitting porcelain veneers in the mouth usually involve a try-in appointment, which frequently results in salivary contamination of fitting surfaces. PURPOSE: An in vitro study was carried out to investigate the effect of silane treatment timing and saliva contamination on the resin bond strength to porcelain veneer surface. MATERIAL AND METHODS: Cylindrical test specimens (n = 360) and rectangular test specimens (n = 5) were prepared for shear bond test and contact angle analysis. Whole cylindrical specimens divided into 20 groups, each of which received a different surface treatment and/or storage condition. The composite resin cement stubs were light-polymerized onto porcelain adherends. The shear bond strengths of cemented stubs were measured after dry storage and thermocycling (3,000 cycles) between 5 and 55 degrees C. The silane and their reactions were chemically monitored by using Fourier Transform Infrared Spectroscopy analysis (FTIR) and contact angle analysis. One-way analysis of variance (ANOVA) and Dunnett' multiple comparison were used to analyze the data. RESULTS: FT-IR analysis showed that salivary contamination and silane treatment timing did not affect the surface interactions of silane. Observed water contact angles were lower on the saliva contaminated porcelain surface and the addition of 37 percent phosphoric acid for 20 seconds on saliva contaminated porcelain increased the degree of contact angle. Silane applied to the porcelain, a few days before cementation, resulted in increasing the bond strength after thermocycling. CONCLUSION: Within the limitation of this study, it can be concluded that it would be better to protect porcelain prosthesis before saliva contamination with silane treatment and to clean the contaminated surface by use of phosphoric acid.
Cementation ; Dental Porcelain ; Mouth ; Phosphoric Acids ; Prostheses and Implants ; Resin Cements ; Saliva ; Spectroscopy, Fourier Transform Infrared ; Water

PURPOSE: Interleukin-12, produced by tissue macrophages and B lymphocytes, stimulates proliferation of Th1-type cells, while inhibiting the generation of Th2- type cytokines and IgE production. The mice were sensitized and challenged with ovalbumin as an allergen to study the effect of IL-12 on the immune responses and the pathologic findings in allergic rhinitis mouse model. METHODS: The animal models were divided into three groups according to the time point of IL-12 trestment intraperitoneally. We measured IL-4, IL-5, and IFN-gamma levels before and after IL-12 treatment. Also we examined the changes of histopathologic findings of mice nasal mucosa. RESULTS: 1) In allergic rhinitis mouse model sensitized and challenged with ovalbumin, IL-4 and IL-5 began to increase on 14 th day and then reached at peak. 2) In pathologic findings, the number of inflammatory cells were increased in the nasal mucosa of allergic rhinitis mice as control without IL-12 treatment, whereas significantly decreased in both IL-12 treated groups than the allergic rhinitis group. 3) The concentration of IL-4 and IL-5 were decreased and IFN-gamma was increased in both IL-12 treated groups than the allergic rhinitis group. And there were no differences of the concentraion of IL-4, IL-5, and IFN-gamma between two groups of mice trested with IL-12 in early and late sensitizing phase. CONCLUSION: These results suggested that both early and late IL-12 treatment inhibited the infiltration of inflammatory cells in nasal mucosa and decreased IL-4 and IL-5 production. Early IL-12 treatment could enhance the allergn specific Th1 immune reactions and late IL-12 treatment could convert Th2 cells to Th1 cells. Finally IL-12 could be applied as an allergen specific immune therapy for allergic rhinitis.
Animals ; B-Lymphocytes ; Cytokines ; Immunoglobulin E ; Interleukin-12* ; Interleukin-4 ; Interleukin-5 ; Macrophages ; Mice* ; Models, Animal ; Nasal Mucosa ; Ovalbumin ; Rhinitis* ; Th1 Cells ; Th2 Cells

No abstract available.
Magnetic Resonance Imaging* ; Neoplasms, Neuroepithelial*