No abstract available.
Child* ; Diverticulum* ; Humans

Backgrounds: Thyroid hormones play a fundamental role in the initiation and maintenance of somatic growth in mammalian species, and the insulin-like growth factors(IGFs) occupy a position of central importance in the growth of all tissues. To evaluate the changes in serum insulin-like growth factor-I(IGF-I) and insulin-like growth factor binding proteins in hyperthyroid and hypothyroid patients, sera was obtained from 19 hyperthyroid patients, 9 hypothyroid patients, and 10 healthy volunteers. Methods: IGF-I concentration was determined by radioimmunoassay, and changes in IGFBPs were assesed by Western Ligand Blotting. To evaluate the binding pattern of IGF-I & IGFBPs, autoradiographs were obtained. Results & Conclusion: IGF-I levels were increased significantly in hyperthyroid patients(mean ±SE, 267.88±9.80 ng/ml, p<0.05) and decreased significantly in hypothyroid patients(154.81±1.43 ng/ml, p<0.01) compaired to healthy control group(209.45±.60 ng/ml). Autoradiograph of serum IGFBPs from patients with hyperthyroidism and hypothyroidism did not show any change in the intensity of IGFBP-3 bands(40-45 KD) and IGFBP-1 bands, but in hyperthyroid patients, it showed increased intensity of IGFBP-2 band compared to healthy control group and hypothyroid patients.
Equidae ; Healthy Volunteers ; Humans ; Hyperthyroidism ; Hypothyroidism ; Insulin-Like Growth Factor Binding Protein 1 ; Insulin-Like Growth Factor Binding Protein 2 ; Insulin-Like Growth Factor Binding Protein 3 ; Insulin-Like Growth Factor Binding Proteins ; Insulin-Like Growth Factor I ; Radioimmunoassay ; Thyroid Hormones

BACKGROUND: Non ulcer dyspepsia(NUD) is a commonly encountered disease at the primary practice. The relations of functional gastrointestinal disorder and Irritable bowel syndrome with depression or stress were suggested by previous studies. But the contributions of the anxiety, depression and stress as a whole to the NUD were not assessed. In this study, we wanted to show the associations of the anxiety, depression and stress levels with NUD. METHODS: This study was performed by case and control method from Aug. 1 to Sep. 7 at the outpatient department of Family Medicine and at the Health Management and Service department in Pusan Paik Hospital. The both groups were matched by sex and age. The case was defined who has three or more symptoms among nine upper gastrointestinal symtoms like dyspepsia, epigastric pain and anorexia etc. frequently or alwalys and who has no ulcer at the gastrofibroscope. The anxiety, depression, stress levels were measured by questionnaire which was validated by previous studies. The questionnaire was composed of Trait-STAI, Jung's Self Depression Scale(SDS), Modified BEPSI, and Grobal Assessment of Recent Stress(GARS) Scale. RESULTS: The total subjects were 136 persons(NUD group : 86 persons/control group : 86 persons). There were. significant differances in regularity of diet(P<0.001), levels of education(P=0.009), and history of medications(P<0.001) between two groups. The two group had higher scores than the control group in the depression score, anxiety score and modified BEPSI score(P<0.001). All items in GARS showed higher scores in NUD group than in control group(P<0.001). CONCLUSIONS: NUD group had higher degree of anxiety and depression than the control group. It seems that the NUD may have streeful status. When we encounter the NUD in outpatiet department, we had better consider the underlying psychogenic or stressful conditions.
Anorexia ; Anxiety* ; Busan ; Depression* ; Dyspepsia* ; Gastrointestinal Diseases ; Humans ; Irritable Bowel Syndrome ; Outpatients ; Ulcer* ; Surveys and Questionnaires

No abstract available.
Foreign Bodies* ; Skull Base* ; Skull*

No abstract available.
Sinusitis*

Adult intussusception is rare, and the majority of cases has an underlying cause that requires surgical resection. We report a case of a 39 yr-old man with ileo-ileo-colic intussusception caused by ileal lipoma that was successfully managed by a laparoscopic-assisted surgical maneuver. Using a three-cannula technique, ileo-colic intussusception was reduced laparoscopically. Then, through a 4-cm transverse incision in the right lower quadrant abdomen, ileo-ileal intussusception was reduced manually, and a resection of the tumor-bearing ileal segment and end-to-end anastomosis was performed extracorporeally. Although the role of laparoscopy in managing intussusception is not clearly defined, laparoscopy may be an alternative approach to the surgical treatment of adult intussusception in selected cases.
Adult ; Case Report ; Human ; Ileal Diseases/surgery* ; Ileal Neoplasms/surgery* ; Intussusception/surgery* ; Laparoscopy ; Lipoma/surgery* ; Male

Purpose: To investigate the long-term clinical outcomes of transplanted amniotic membrane in patients who underwent permanent amniotic membrane transplantation (P-AMT) on cornea. Methods: From April 2014 to March 2021, medical records and digital photographs of 68 patients (72 eyes) who underwent P-AMT were analyzed retrospectively. The duration of complete re-epithelization of cornea and wearing therapeutic contact lense (T-lens) after surgery were investigated, the size of preserved amniotic membrane (AM) excluding the melted portion was analyzed using the Image J program every year up to 6 years after surgery, and it was compared by dividing into a single-layer group and a double-layer group. In addition, when the AM melts, the cause, time, and related factors of melting were analyzed. Results: The average duration to complete re-epithelialization after surgery was 12.2 ± 11.0 days, and T-lens were worn on average up to 8.7 ± 8.5 months after surgery. In total group, the average ratio of preserved AM annually up to 6 years after surgery was 94.9%, 94.3%, 97.8%, 96.4%, 95.8%, 91.6% respectively, and there was no significant difference between the single-layer group and the double-layer group. AM melting appeared in 38.9% (28 eyes) of the total group, and melting was first observed on average 16.4 ± 17.2 months after surgery. The formation and rupture of bullae was the most common cause of melting at 71.4% (20 eyes), and there were no statistically significant related factors involved in the formation of bullae. Conclusions In the case of P-AMT performed in various diseases of the cornea, the transplanted AM is partially melt but considered to be well preserved up to 6 years after surgery to form a stable ocular surface.

BACKGROUND: It is known that QT dispersion represents asynchronous repolarization of ventricle which is related to ventricular fibrillation. The incidence of ventricular arrhythmia is increased after acute myocardial infarction. So this study compared QT dispersion and other repolarization indexes for detection of asynchronous repolarization in acute myocardial infarction. We also investigated which portion of repolarization is the key portion of the asynchrony. METHODS: In 37 acute myocardial infarction patients and 38 angina patients dispersion of QT, JT, JTpeak and QTpeak were measured. We also measured maximum adjacent dispersion of same parameters in precordial leads. In 20 survived patients and 17 dead patients after acute myocardial infarction were also compared. We also investigated correlation of PVC's on Holter monitoring with these repolarization parameters. RESULTS: 1) All ventricular repolarization indexes(QT, QTc, JT, JTpeak, QT peak and TpeakTend dispersion) were significantly increased in acute myocardial infarction group than compared with those of angina group(p<0.05). 2) Maximal precordial dispersion(QT, QTc, JT, JTpeak and QTpeak) were also significantly increased in acute myocardial infarction group than angina group(p<0.05). 3) Dead patient group after myocardial infarction showed significantly increased QTc and TpeskTend dispersion compared with those of survived patient group(p<0.05). 4) Multivariate linear correlation showed that TpeakTend dispersion and JT dispersion was correlated with QT dispersion. CONCLUSIONS: There were asynchronous myocardial repolarization changes in acute myocardial infarction. Our study demonstrated that T wave change was major determinant of dispersion of myocardial repolarization.
Arrhythmias, Cardiac ; Electrocardiography, Ambulatory ; Humans ; Incidence ; Myocardial Infarction* ; Ventricular Fibrillation

OBJECTIVES: This study aimed to investigate the relationship between internet addiction and emotional and behavioral problems in 5th and 6th grade elementary school students and middle school students. METHODS: Two elementary school and two middle schools were chosen to participate. The participants completed self-report questionnaires designed by authors, an internet addiction scale, and the Korean Youth Self Report (K-YSR). RESULTS: The prevalence of internet addiction was 1.5%. We defined the upper 30% of internet addiction scores as an addiction tendency group and the lower 30% as a control group. There were significant differences in the gender ratio, age, and average length of each internet use, years of internet use experience, and exposure to pornography between the two groups. Linear regression analysis showed that significant association was found between internet addiction scores and withdrawn problems in middle school students but not in elementary school students. The level of internet addiction was associated with a high occurrence rate of total behavioral problems and delinquent behavior problems in boys and depression/anxiety problems in girls. CONCLUSION: This data supports that withdrawn and delinquent behaviors could be predictable factors of internet addiction, and gender differences may exist in the development of internet addiction. The intervention focused on these findings could be effective to prevent and treat internet addiction in children and adolescents.
Adolescent ; Child ; Erotica ; Humans ; Internet ; Linear Models ; Prevalence ; Psychopathology ; Surveys and Questionnaires ; Self Report

BACKGROUND: This is a cross sectional study to assess the effect of BMI (body mass index) on blood pressure and to get the appropriate BMI range for the prevention and control of hypertension in old men and women. METHODS: From 1996 to 1998 we obtained data for anthropometrics, blood pressure, serum blood profiles and health behaviors about 418 out of 668 old people having visited a charge free clinic in rural areas. First we tried to figure out the relationship between BMI and systolic or diastolic blood pressure in old men and women separately. After adjusting age, smoking, alcohol, blood glucose, total cholesterol, we checked the linear relationship between each quintile BMI group and prevalence of hypertension in old men and women and obtained prevalence odds ratio (POR) for hypertension in each the 2nd to the 5th quintile BMI group compared to the baseline hypertension prevalence of the 1st quintile BMI group. RESULTS: Regardless of sex, there was significant correlations between BMI and systolic blood pressure (in men r=0.257, p=0.002;in women r=0,182 p=0.005) or diastolic blood pressure (in men r=0.204, p=0.014;in women r=0.256 p<0.001). The prevalence of hypertension in men and women increased 1.37 and 1.41 times respectively by each quintile BMI increase. According to each quintile BMI group in men (median BMI value of each quintile group;18.2, 20.4, 21.8, 23.3, 26.6 kg/m2), PORs for hypertension were 1.0, 3.7(95% C.I;1.05 12.68), 3.6(95% C.I;1.03 12.59), 6.5(95% C.I;1.89 22.29), 4.0 (95% C.I;1.11 14.36). In women, (median BMI value of each quintile group;18.6, 21.3, 22.9, 25.1, 28.3 kg/m2), PORs for hypertension were 1.0, 1.6(95% C.I;0.62 3.82), 2.9(95% C.I;1.22 6.99), 2.9(95% C.I;1.28 6.68), 4.2(95% C.I;1.73 9.98). CONCLUSION: Regardless of sex, there was a significant positive association between BMI and prevalence of hypertension in the old and the risk of hypertension increased even in normal weight group compared to the underweight group. Further studies on the appropriate weight range to prevent and control hypertension in old people will be needed.
Aged* ; Blood Glucose ; Blood Pressure ; Body Mass Index* ; Cholesterol ; Female ; Health Behavior ; Humans ; Hypertension* ; Male ; Odds Ratio ; Prevalence ; Smoke ; Smoking ; Thinness