A 46 year old man with unilateral Purtscher's retinopathy is described. On ophthalmic examination he had macular edema and multiple exudates and hemorrhages at the posterior pole of the left eye. Fluorescein angiography demonstrated impaired arteriolar flow, capillary non-per fusion, venous staining, and macular edema. The pathogenesis of Purtscher's retinopathy is unknown. Arterial and venous pressure elevation leading to vascular damage in the nerve fiber layer seems to be the most plausible explanation.
Capillaries ; Exudates and Transudates ; Fluorescein Angiography ; Hemorrhage ; Humans ; Macular Edema ; Middle Aged ; Nerve Fibers ; Venous Pressure

Squamous cell carcinoma of the conjunctiva is a rare disease and usually arises at the limbus and spreads to the cornea, adjacent bulbar conjunctiva and sclera. We experienced two cases of squamous cell carcinoma of the cornea and bulbar conjunctiva. One patient was a 36-year old male with progressive loss of visual acuity and discomfort in the nasal side of the left eyeball for about 7 months. The other patient was a 67-year old male with excessive tearing, recurrent conjunctival injection and elevated mass on inferonasal side of the limbus of the left eye. Excisional biopsy was carried out and histopathologic examination revealed bulbar squamous cell carcinoma in both patients.
Adult ; Aged ; Biopsy ; Carcinoma, Squamous Cell* ; Conjunctiva* ; Cornea ; Humans ; Male ; Rare Diseases ; Sclera ; Visual Acuity

Diabetic macular edema is the most frequent cause of visual loss among patients with background diabetic retinopathy. We reviewed 62 cases(39 patients) of diffuse diabetic macular edema which were treated by grid-pattern photocoagulation treatment and followed up for more than 3 months from March 1989 to July 1990. The results were as follows. 1. There was improvement of visual acuity in 13 eyes(21.0%), no changes in 33 eyes(53.2%), and 16 eyes(25.8%) showed worsened visual acuity. 2. There was improvement in the degree of macular edema in 28 eyes(45.7%), no change in 15 eyes(24.2%), and 19 eyes(30.6%) showed a worsened degree of macular edema. 3. Clinical findings having poorer visual prognoses were the presence of foveal exudate, hypertension, preoperative vision worse than 20/100, and proliferative diabetic retinopathy.
Diabetic Retinopathy ; Exudates and Transudates ; Humans ; Hypertension ; Light Coagulation* ; Macular Edema* ; Prognosis ; Visual Acuity

Retinoblastoma is a rare, congenital, malignant tumor that arises from the retina. It is the most common intraocular tumor occurring during childhood. Retinoblastoma usually remains unnoticed until it has advanced far enough to produce a white pupil. But it may manifest as a painful, red, tearing eye due to secondary glaucoma. The most common mechanism inducing secondary glaucoma in retinoblastoma is neovascularization of iris with peripheral anterior synechiae formation. The next common mechanism is massive exudative retinal detachment causing pupillary block and angle closure. Uveitis and/or necrotic tumor tissue in anterior chamber acn contribute to the development of secondary glaucoma. A 9 month old Korean boy was seen to have somewhat enlarged cornea with massive exudation in anterior chamber OS. Intraocular pressure was 27.4 mmHg OS. The C-T scan was done because of hazy media OS. and showed calcification within left eye. Left eye was enucleated and found to have retinoblastoma which was confirmed microscopically.
Anterior Chamber ; Cornea ; Glaucoma* ; Humans ; Infant ; Intraocular Pressure ; Iris ; Male ; Pupil ; Retina ; Retinal Detachment ; Retinoblastoma* ; Tears ; Uveitis

Macroglobulinemia is the result of an uncontrolled proliferation of lymphocytes and plasma cells in which a large IgM M protein is produced. IgM monoclonal gammopathy is recognized in a variety of lymphoproliferative diseases and Waldenstr?m's macroglobulinemia (WM) is the most frequent disease in this group. We report a case of nodal marginal zone B-cell lymphoma (Nodal MZBCL) accompanied by monoclonal macroglobulinemia. A 58-year-old man was admitted to the hospital with chronic fatigue and dyspnea. Physical examination revealed cervical, subaxillary, and inguinal lymphadenopathy. Histopathologically, monocytoid B cells with abundant pale cytoplasm and small nuclei infiltrated the cervical lymph node. The neoplastic cells were positive for CD 20, bcl-2, and IgM. The serum and urine electrophoresis showed monoclonal spike in the globulin region and immunoelectrophoresis demonstrated immunoglobulin of IgM, kappa type. Immunohistochemically, this monoclonal gammaglobulinemia (IgM, Kappa) was produced and secreted from the nodal MZBCL. This is the first report of nodal MZBCL accompanying macroglobulinemia in Korea.
B-Lymphocytes ; Cytoplasm ; Dyspnea ; Electrophoresis ; Fatigue ; Humans ; Immunoelectrophoresis ; Immunoglobulin M ; Immunoglobulins ; Korea ; Lymph Nodes ; Lymphatic Diseases ; Lymphocytes ; Lymphoma, B-Cell, Marginal Zone* ; Middle Aged ; Paraproteinemias ; Physical Examination ; Plasma Cells ; Waldenstrom Macroglobulinemia*

A metastatic melanoma to the gastrointestinal tract is observed in 1.5~4.4% of all melanoma patients. However, colonic and rectal involvement is less common. A 72-year-old woman was admitted due to abdominal pain and poor oral intake for 20 days. She had a 3 x 4 cm-sized mass on her right inguinal area 4 month ago, which was diagnosed as a malignant melanoma of the inguinal lymph node on excision biopsy. A large exophytic mass with an irregular ulcerlated, whitish patch, erythematous surface was observed in the hepatic flexure during colonoscopy. A histology diagnosis of a metastatic melanoma was made by an optical microscopy examination of the biopsies obtained during the colonscopy, and palliative right hemicolectomy was performed on account of a potential intestinal obstruction. We report a case of a metastatic melanoma of the colon with a review of the relevant literature.
Abdominal Pain ; Aged ; Biopsy ; Colon* ; Colonoscopy ; Diagnosis ; Female ; Gastrointestinal Tract ; Humans ; Intestinal Obstruction ; Lymph Nodes ; Melanoma* ; Microscopy