1.Detection of somatostatin mRNA by in situ hybridization histochemistry in the rat brain; I. telencephalon and diencephalon.
Korean Journal of Anatomy 1991;24(1):93-101
No abstract available.
Animals
;
Brain*
;
Diencephalon*
;
In Situ Hybridization*
;
Rats*
;
RNA, Messenger*
;
Somatostatin*
;
Telencephalon*
2.Lectins Binding in Squamous Cell Carcinoma of the Uterine Cervix as a Diagnostic and Prognostic Marker.
Yu Seon MIN ; Jae Seong KANG ; In Sun KIM
Korean Journal of Obstetrics and Gynecology 2000;43(5):787-794
OBJECTIVE: The aim of the study was to evaluate the corelation between an expression of lectins and survival of patients with squamous cell carcinoma of uterine cervix. METHODS: The cell surface carbohydrate profile of formalin-fixed paraffin embedded tissue section of squamous cell carcinoma of the uterine cervix was evaluated using ulex europaeus agglutinin(UEA-1), peanut agglutinin(PNA), dolichos biflorus agglutinin(DBA), soybean agglutinin(SBA) and lotus tetragonobus lectin(LTL) by the avidin-biotin complex method. Fifty-one cases of squamous cell carcinoma and 10 cases of normal squamous epithelium of the uterine cervix were selected from the file which were treated during Jan. 89 to 31 Dec. 1992 in Department of Obstetrics and Gynecology, Korea University Hospital. RESULTS: UEA-1 and LTL were negative in normal cervix while positive in 76.5%, 47.1% of squamous cell carcinoma respectively, and useful markers for differential diagnosis between normal and squamous cell carcinoma. SBA and LTL were useful for differential diagnosis of keratinizing and non-keratinizing squamous cell carcinoma. UEA-1 may play an important role in lymphovascular invasion of squamous cell carcinoma of the uterine cervix. CONCLUSIONS: There was no correlation among clinical staging, patient's survival and lectins binding in squamous cell carcinoma.
Carcinoma, Squamous Cell*
;
Cervix Uteri*
;
Diagnosis, Differential
;
Dolichos
;
Epithelium
;
Female
;
Gynecology
;
Humans
;
Korea
;
Lectins*
;
Lotus
;
Obstetrics
;
Paraffin
;
Soybeans
;
Ulex
3.A Study of Antihypertensive Effect of Isradipine(Dynacirc).
Hyun Seung KIM ; Jae Hwa CHO ; Seon Ok KWON
Korean Circulation Journal 1992;22(1):146-150
Essential hypertension is an important public health problem in Korea-being common, asymptomatic, easily treatable, and often leading to lethal complication in left untreated. The number of patients with hypertension has been significantly increased, and this factor may be an importnat one responsible for the increase in cardivascular mortality during past 20 years in Korea. As the drug therapy for hypertension needs longer period, it is very important to evaluate the efficacy and the adverse effects. Thirty patients(17 men and 13 womon) with essential hypertension were evaluated in this study. All patients had received oral Isradipine 1.25~2.5mg b.i.d. for 8 weeks. 1) The systolic and diastolic pressure were decreased significantly(166.8+/-9.0mmHg vs 147.3+/-12.0mmHg, p<0.001 and 100.3+/-4.0mmHg vs 90.3+/-6.1mmHg, p<0.001, respectively) 2) Heart rate, body weight, laboratory tests, chest X-ray, ECG studies were not changed significantly. 3) The systolic pressure was lowered by 20mmHg or more in 17 cases(56.7% of total), and the diastolic pressure was lowered by 10mmHg or more in 20 cases(66.7% of total) at 8 weeks after Isradipine administration. 4) The adverse effects of Isradipine were edema in 3(10%), constipation in 2(6.7%), headache in 2(6.7%), and insomnia, dizziness and dry mouth in 1 patient respectively, and none of them discontinued Isradipine administration due to adverse effects. In many patients with essential hypertension there is an effective response to Isradipine, even though there may be some mild adverse effects.
Blood Pressure
;
Body Weight
;
Constipation
;
Dizziness
;
Drug Therapy
;
Edema
;
Electrocardiography
;
Headache
;
Heart Rate
;
Humans
;
Hypertension
;
Isradipine
;
Korea
;
Male
;
Mortality
;
Mouth
;
Public Health
;
Sleep Initiation and Maintenance Disorders
;
Thorax
4.Radiological study on the primary tuberculous lesions
Dae Hong BANG ; Hyo Seon CHUNG ; Jae Seop KIM
Journal of the Korean Radiological Society 1983;19(3):637-641
The simple chest X-ray study is essential in diagnosis of pulmonary tuberculosis, especially primary pulmonarytuberculosis. Authers analyzed the chest films and tuberculin tests of 521 cases which are suspected primarypulmonary tuberculosis coinically, from Jan. 1978 to Nov. 1982 at Seoul Red Cross Hospital. The results are asfollows; 1. Among the total 521 cases, the 115 cases of chst film reveal 245 probable pulmonary tuberculouslesions. 2. The coincidence of the parenchymal and lymphnodal involvement are observed in 40 cases (34.8%) with137 lesions(55.9%), parenchymal only in 23 cases (20.0%) with 25 lesions(10.2%) and lymphnodal only in 52 cases(45.2%) with 83 lesions(33.9%). 3. In observing the distribution of the 83 parenchymal lesions, the right lung istwo times as common as that of the left, being the highest in the RLL field with 41 lesions(49.4%), the lowest inthe LLL field with 3 lesions(3.6%). 4. In observing the distribution of the 162 lymphnodal lesions, there are 95lesions(58.6%) in the right and 67 lesions(41.4%) in the left, involving hilar nodes with 150 lesions(92.6%) andmediastinal nodes with 12 lesions(7.4%). The incidence of unilateral involvement is 13 cases (11.3%) and bilateral79 cases (68.7%). 5. Among the total 245 lesions, 141 lesions(57.9%) are smaller than rice in size, 120lesions(49.0%) are amophous in shape and 186 lesions(75.9%) are mainly calcific in density. According to theincrease of age, count and detection rate of the lesion on the chest film are increased. 6. Tuberculin testsshowed 26.1% negative rate in 115 tuberculous cases, and 51% positive rate in 406 negative chest cases.
Diagnosis
;
Incidence
;
Lung
;
Red Cross
;
Seoul
;
Thorax
;
Tuberculin
;
Tuberculin Test
;
Tuberculosis
;
Tuberculosis, Pulmonary
5.Psychiatric Consultation for 5 Years in a University Hospital.
Sung Wan KIM ; Seon Young KIM ; Sung Jin KIM ; Jae Min KIM ; Il Seon SHIN ; Jin Sang YOON
Korean Journal of Psychosomatic Medicine 2011;19(1):28-33
OBJECTIVE: This study aimed to investigate the pattern of psychiatric consultation-liaison in a new general hospital over a 5-year period. METHOD: Retrospective chart review was conducted for psychiatric consultations performed from May 2004 to December 2008 in a new general hospital in Hwasun, Korea. RESULTS: A total of 1,852 patients who were referred to the Department of Psychiatry for consultation were included in the analysis. The main reasons for psychiatric consultation were changes in mental status(20.5%), depression(16.8%), insomnia(12.8%), and anxiety(7.9%). Psychiatric consultations were conducted with diagnoses of delirium(39.7%), depressive disorder(28.2%), adjustment disorder(7.9%), and anxiety disorder(4.1%). Patients with delirium were significantly older than were those with other psychiatric diagnoses(p<0.001). Delirium was more common in male patients than in female patients(47.1% vs. 29.9%, respectively), and depression was more common in female patients than in male patients(48.3% vs. 33.9%, respectively)(p<0.001). Delirium was more common in patients who underwent surgical operation than those who did not(p=0.010). CONCLUSION: Delirium was the most common diagnosis for psychiatric consultation followed by depression in a university hospital. Delirium was more prevalent in men than in women, while depression was more common in women.
Anxiety
;
Delirium
;
Depression
;
Female
;
Hospitals, General
;
Humans
;
Male
;
Referral and Consultation
;
Retrospective Studies
6.Production of monoclona antibody to infectious bursal disease virus as a diagnostic methods.
Hyung Kwan JANG ; Jai Hong KIM ; Chang Seon SONG ; Soon Jae KIM ; Tae Jong KIM
Journal of the Korean Society of Virology 1993;23(2):171-182
No abstract available.
Infectious bursal disease virus*
7.Distribution of the various neurotransmitter containing neurons in the rat olfactory bulb:an immunohistochemical analysis.
Jin Jeong KIM ; Jae Bong KIM ; Bong Seon KIM ; Sun Yong BAEK
Korean Journal of Anatomy 1993;26(4):361-376
No abstract available.
Animals
;
Neurons*
;
Neurotransmitter Agents*
;
Rats*
8.A clinical analysis of the operative treatment in hallux valgus.
Jang Jung KIM ; Taik Keun AHN ; Jong Oh KIM ; Taik Seon KIM ; Jae Ik SHIM
The Journal of the Korean Orthopaedic Association 1992;27(4):937-945
No abstract available.
Hallux Valgus*
;
Hallux*
9.Changes of the signal transduction system by transneuronal regulation in the olfactory bulb.
Jin Jeong KIM ; Jae Bong KIM ; Bong Seon KIM ; Sun Yong BAEK
Korean Journal of Anatomy 1993;26(1):41-49
No abstract available.
Olfactory Bulb*
;
Signal Transduction*
10.A Clinical Analysis of Arthrodesis of the Ankle Joint
Jung Ki KIM ; Taik Seon KIM ; Young Jong CHOI ; Jae Ik SHIM ; Dong Eun KIM
The Journal of the Korean Orthopaedic Association 1987;22(4):835-841
The method of ankle arthrodesis is variable but compression arthrodesis has been widely used because of better results than non-compression arthrodesis. Twenty-one cases of ankle arthrodesis were carried out at department of orthopaedic surgery of Korea Veterans Hospital from January 1980 to June 1986, and were analysed clinically. The results obtained were as follows; l. Among 11 cases of compression arthrodesis, Charnleys method was done in 8 cases and Monofixateur in 3 cases. 2. Among 10 cases of non-compression arthrodesis, Chuinard-Peterson method was done in 7 cases and anterior 'sliding graft in 3 cases. 3. The average duration of immobilization after ankle arthrodesis was 11.7 weeks, and average 4.2 weeks were less needed in the compression arthrodesis than non-compression arthrodesis. 4. The postoperative complications were developed in 8 cases (38%): wound infection in 4 cases,skin necrosis in 3 cases and incisional neuroma in 1 case. 5. Bony union was obtained in 20 cases(95.2%) out of 21 cases at average 15.7 weeks, and in the non-compression arthrodesis and in the cnmpression arthrodesis, respectively, 90% at 17.7 weeks and 100% at 13.9 weeks.
Ankle Joint
;
Ankle
;
Arthrodesis
;
Hospitals, Veterans
;
Immobilization
;
Korea
;
Methods
;
Necrosis
;
Neuroma
;
Postoperative Complications
;
Transplants
;
Wound Infection