No abstract available.
Fibronectins* ; Staphylococcus aureus* ; Staphylococcus*

The purpose of this study was to analyzed the effects of step aerobics on the health-related fitness in the middle school girl's Sasang Constitution Classification. The Sasang Constitution was classified by QSCCII and Sasang Pattern Identification Questionnaire and then confirmed by expert of this field, who was oriental medical doctor, attending to Dongeui oriental medical center in Busan. The subjects were Soyang-in 10, Soeum-in 10, Taeum-in 10, respectively, total 30 middle school girls. Step Aerobics program performed 45 min/day, 3 times/week, during 12 weeks. The result was as follows : 1. The height was increased significantly than before exercise in Soeum-in. The body weights and chest circumference were increased than that of the pre-test values in the girl with Soyang-in, Soeum-in, and Taeeum-in, respectively but there was lettle significance. 2. The sit-ups, sit and reach test's values were significantly improved than pre test, and %fat was decreased significantly in Soeum-in and Taeum-in. Otherwise, BMI and LBM were slightly increased than pre-exercise but there was no significance.
Body Weight ; Busan ; Classification ; Constitution and Bylaws* ; Female ; Humans ; Surveys and Questionnaires ; Thorax

PURPOSE: Periodic lateralized epileptiform discharges (PLEDs), initially described by Chatrian et al in 1964, are an EEG phenomenon characterized by lateralized or focal spike-and-wave complexes with moderate to high voltage which occur in a periodic or semiperiodic pattern. This study was performed to assess the clinical significance of PLEDs and its relation to an imaging study of the brain. MEHTODS: Twenty children (10 males and 10 females), from 2 days to 14 years of age, who had been hospitalized at Hanyang University Hospital were studied retrospectively. Their medical records, EEG results and brain imaging study were reviewed. RESULTS: Of the 20 patients studied, 15 patients showed unilateral PLEDs and 5 had bilateral PLEDs in EEG. Brain imaging studies were done for 18 of the patients, revealing abnormalities in 15 patients in this order of frequency: intracranial hemorrhage, diffuse cerebral atrophy, leukomalacia, cerebral infarctions, cerebral edema and hydrocephalus. PLED sites were not significantly correlated with the results of the imaging study. Finally, 3 patients died and 17 patients survived, and among the surviving 17 patients, 5 had recurrent seizures, 1 had recurrent seizures with mental regression, 3 had neurologic sequelae without seizures and 8 had no neurologic sequelae. CONCLUSION: We conclude that children who show PLEDs in EEG are more commonly associated with acute cerebral lesions and there is a high incidence of subsequent seizures and/or other neurological sequelae in surviving children with PLEDs.
Atrophy ; Brain Edema ; Brain* ; Cerebral Infarction ; Child* ; Electroencephalography ; Humans ; Hydrocephalus ; Incidence ; Intracranial Hemorrhages ; Male ; Medical Records ; Neuroimaging* ; Retrospective Studies ; Seizures

PURPOSE: Periodic lateralized epileptiform discharges (PLEDs), initially described by Chatrian et al in 1964, are an EEG phenomenon characterized by lateralized or focal spike-and-wave complexes with moderate to high voltage which occur in a periodic or semiperiodic pattern. This study was performed to assess the clinical significance of PLEDs and its relation to an imaging study of the brain. MEHTODS: Twenty children (10 males and 10 females), from 2 days to 14 years of age, who had been hospitalized at Hanyang University Hospital were studied retrospectively. Their medical records, EEG results and brain imaging study were reviewed. RESULTS: Of the 20 patients studied, 15 patients showed unilateral PLEDs and 5 had bilateral PLEDs in EEG. Brain imaging studies were done for 18 of the patients, revealing abnormalities in 15 patients in this order of frequency: intracranial hemorrhage, diffuse cerebral atrophy, leukomalacia, cerebral infarctions, cerebral edema and hydrocephalus. PLED sites were not significantly correlated with the results of the imaging study. Finally, 3 patients died and 17 patients survived, and among the surviving 17 patients, 5 had recurrent seizures, 1 had recurrent seizures with mental regression, 3 had neurologic sequelae without seizures and 8 had no neurologic sequelae. CONCLUSION: We conclude that children who show PLEDs in EEG are more commonly associated with acute cerebral lesions and there is a high incidence of subsequent seizures and/or other neurological sequelae in surviving children with PLEDs.
Atrophy ; Brain Edema ; Brain* ; Cerebral Infarction ; Child* ; Electroencephalography ; Humans ; Hydrocephalus ; Incidence ; Intracranial Hemorrhages ; Male ; Medical Records ; Neuroimaging* ; Retrospective Studies ; Seizures

PURPOSE: Violence in the Emergency Department is a common concern but it is an ill-defined and underreported problem because no organization or administrative guidelines exist to adequately address it. The aim of this effort was to gather demographic information on the persons responsible for the violence and on the causes of the violence, so we would have basic data for the prevention of such violence. METHODS: The answers of Emergency Department doctors and nurses working in tertiary, university hospitals in South Korea to questions on a prospective questionaires during the period from December 2002 through February 2003 were analyzed. The survey used 10 questions to elicit demographic information on the persons responsible for the violence, the degree of violence, the severity of the patient' s disease and the reason for the violence. RESULTS: Two hundred twenty-five (225) cases of violence in the emergency department were reported from 6 tertiary hospitals during the 2-month duration. Total respondents to the questionaires were 225 (6 staffs, 131 nurses, and 88 residents). Verbal insults and threats were the most common form of violence. Almost all of the violence was due to the male gender, and 74.5% of violence was done by patient's guardians. More than half of those responsible for the violence were in an alcohol-drunken state. The causes of violence were long waiting time and poor patient-practitioner relationship and were not related with the severity of disease. CONCLUSION: If violence in the emergency department is to be managed and/or prevented, more administrative and financial efforts, a regular format for documentation of incidents, regular preventive education, and further study, if possible, with the Korean Society of Emergency Medicine are necessary.
Surveys and Questionnaires ; Education ; Emergencies* ; Emergency Medicine ; Emergency Service, Hospital* ; Hospitals, University ; Humans ; Korea ; Male ; Prospective Studies ; Tertiary Care Centers ; Violence*

No abstract available.
Escherichia coli* ; Escherichia* ; HeLa Cells* ; Humans ; Virulence Factors* ; Virulence*

A 25-year-old 7 month pregnant woman with mitral stenosis was hospitalized because of life threatening hemoptysis dispite intensive medical treatment. Emergency mitral commissurotomy resulted in prompt cessation of hemorrhage and at nine months follows-up, the hemoptysis has not recurred. Mitral valve surgery appears to be consitently associated with rapid and sustained cessation of hemoptysis. Therefore, surgery should be considered in hemoptysis due to mitral stenosis, particulary when the danger of asphyxiation exists.
Adult ; Emergencies* ; Female ; Hemoptysis* ; Hemorrhage ; Humans ; Mitral Valve ; Mitral Valve Stenosis* ; Pregnant Women

No abstract available.
Plasmids* ; Shigella* ; Virulence Factors* ; Virulence*

To identify the role of the myocardial beta-adrenergic pathway in congestive heart failure, we examined beta-adrenergic receptor density and C-AMP by receptor assay with mononuclrear cell and polymorphonuclear cell in 7 cases of normal control and 7 cases of congestive heart failure. The results were as follows: 1)The mean serum concerntrations of norepinephrine(566.00+/-48.12 pg/ml)and epinephrine(353.14+/-44.24 pg/ml) in congestive heart failure group were significantly higher than those(218.12+/-17.08 pg/ml, 187.23+/-24.62 pg/ml)in normal contral group(P<0.05 for each comparison). 2) In normal control group, the receptor concentration of mononuclear cell was 35.51+/-19.19 fmol/mg and that of polymorphonuclrear cell was 35.53+/-15.05 fmol/mg. The affinity constant of mononuclear cell was(2.47+/-0.42)x10(9)/m and that of polymorphonuclear cell was(2.24+/-0.58)x10(9)/m. 3) In congestive heart failure group, the receptor concentration of mononuclear cell(29.31+/-5.41 fmol/mg) was significantly lower than that in normal control group(p<0.05). And the affinity constant(3.57+/-1.02)x10(9)/m) was significantly higher than that in normal control group(p<0.05). 4) In congestive heart failue group, the receptor concentration of polymorphonuclear cell(33.15+/-10.46 fmol/mg) was not significantly different from that in normal control group. And the affinity constant(2.66+/-0.43)x109/m) was not significantly different from that in normal control group. 5) In congestive heart failure group, the C-AMP concentrations of mononuclear cell(basal 119.9+/-17.2 pmol/min/mg, isoproterenol stimulation 137.2+/-23.2 pmol/min/mg) were significantly lower than those(basal 205.2+/-21.1 pmol/min/mg, isoproterenol stimulation 267.5+/-34.3 pmol/min/mg) in normal control group(p<0.05 for each comparison). 6) In congestive heart failure group, the C-AMP concentrations of polymorphonuclear cell(basal 115.2+/-34.3 pmol/min/mg, isoproterenol stimulation 142.5+/-20.5 pmol/min/mg) were significantly lower thatn those(basal 186.3+/-24.2 pmol/min/mg, isoproterenol stimulation 233.4+/-32.2 pmol/min/mg) in normal control group(P<0.05 for each comparison). In conclusion, a decrease in beta-adrenergic density in congestive heart failure leads to subsensitivity of the beta-adrenergic pathway and decreased beta-agonist-stimulated contraction. However, other factors may be important in adenylate cyclase activation, and so further research is needed.
Adenylyl Cyclases ; Estrogens, Conjugated (USP)* ; Heart ; Heart Failure* ; Isoproterenol ; Plasma*

Although ionizing radiation is known to induce cellular senescence in vitro and in vivo, its long-term in vivo effects are not well defined. In this study, we examined the prolonged expression of senescence markers in mice irradiated with single or fractionated doses. C57BL/6 female mice were exposed to 5 Gy of gamma-rays in single or 5, 10, 25 fractions. At 2, 4, and 6 months after irradiation, senescence markers including mitochondrial DNA (mtDNA) common deletion, p21, and senescence-associated beta-galactosidase (SA beta-gal) were monitored in the lung, liver, and kidney. Increases of mtDNA deletion were detected in the lung, liver, and kidney of irradiated groups. p21 expression and SA beta-gal staining were also increased in the irradiated groups compared to the non-irradiated control group. Increases of senescence markers persisted up to 6 months after irradiation. Additionally, the extent of mtDNA deletion and the numbers of SA beta-gal positive cells were greater as the number of radiation fractions increased. In conclusion, our results showed that ionizing radiation, especially that delivered in fractions, can cause the persistent upregulation of senescence marker expression in vivo. This should be considered when dealing with chronic normal tissue injuries caused by radiation therapy or radiation accidents.
Aging ; Animals ; Cell Aging ; DNA, Mitochondrial ; Female ; Humans ; Kidney ; Liver ; Lung ; Mice ; Radiation, Ionizing ; Radioactive Hazard Release ; Up-Regulation ; beta-Galactosidase