No abstract available.
Hyperplasia*

It is common to administrate neostigmiae methylsulfate and atropiae aulfate to counteract the effect of nondepolarising neuromuscular blocker. In case of cardiovascular disease, the effect of bradycardia or tachycardia resultiag from the administration of these drugs may be harmful to the patient. The purpose of this study is to investigate the effects of combinatioa and method of administration of neostigmine methylsulfate and atropine sulfate on heart rate. One hundred and two patients in both sexes were devided into three groups(A, B, C), and each group was devided into three subgroups (AI, AII, AIII, BI, BII, BIII, CI, CII, CIII). In group A, neostigmine methylsulfate and atropine aulfate were mixed and administered intravenously within fifteen seconds. In group B, atropine eulfate was administered thirty seconds after the administration of neostigmine methylsulfate. In group C, the two drugs were mixed and administered over a period of five minutes. In subgroup I the ratio of neostigmine methyliulfate to atropine sulfate was 2: 1(0. 04 mg/kg: 0.02 mg/kg) in subgroup 3 the ratio was 3: 2(0.03 mg/kg: 0. 02 mg/kg), and in subgroup lll the ratio was 1: 1(0. 02 mg/kg: 0. 02 mg/kg). The heart rate was counted just before, 0. 5 minute, 1 miaute, l. 5 minutes, 2 minutes, 3 minutes, 5 minutes, 10 minutes, 15 minutes, 20 minutes, 25 minutes, 30 minutes after the administration of the drugs. The results were as follows: 1) Initial increase in heart rate was significant in lager atropine ratio. 2) The later decrease in heart rate waa less in larger atropine ratio. 3) The maximal increases in heart rate in groap A and B appeared thirty seconds apart, but there was little difference betweea them. 4) The change ia heart rate was the least in group C.
Atropine* ; Bradycardia ; Cardiovascular Diseases ; Heart Rate* ; Heart* ; Humans ; Neostigmine ; Neuromuscular Blockade ; Tachycardia

BACKGROUND: In two-kidney one clip Goldbaltt hypertensive rats(2K1C GHR), clipped kidney may be exposed to low pressure and unclipped kidney to high pressure. In addition, both kidneys may have a different amount of adenosine which is increased by ischemia and plays an important role for renin release. The aim of this study was to invstigate the responsmiveness for renin release to adenosine agonists and antagonist in clipped and unclipped kidney of 2K1C GHR. METHODS: Emplying kidney slices from both unclipped and unclipped kidney of 2K1C GHR, the alteration by adenosine agonists and antagonist of renin release was studied. RESULTS: The renal renin content and basal renin release from unclipped kidney slices were suppressed, whereas those from clipped kidney were augmented Adenosine Al receptor agonist, cyclohexyladenosne(CHA), phenylisopropyl adenosine(PIA) and adenosine caused a decrease in renin release from clipped kidney slices. Adenosine A2 receptor agonist, NECA, and nonspecific adenosine receptor aganist, 2-chloroadenosine(CA) caused an increase in renin release from clipped kidney slices. Adenosine receptor antagonist, 8-phenyltheophylline(8-PT) caused an increase in renin release from clipped kidney slices. In unclipped kidney, however, the renin release in response to NECA, CA or 8-PT was reversed and the decreasing effect of renin release to CHA and adenosine was slightly inereased. CONCLUSION: These results suggest that the responsiveness of adenosine receptors, which may participate in renin release is modified in clipped and unclipped kidney of 2K1C GHR.
Adenosine* ; Adenosine-5'-(N-ethylcarboxamide) ; Animals ; Hypertension, Renovascular ; Ischemia ; Kidney ; Rats* ; Receptors, Adenosine A2 ; Receptors, Purinergic P1 ; Renin*

The maternal and neonatal effects of 50% O2 -50% N2O alone and 50r% O2-5O% N2O combined with 0.5% halothane or 1% enflurane were studied in 37 parturients undergoing general anesthesia for cesarean section, All patients received thiopental and succinrlcholine for induction and were intubated and ventilated with a tidal volume of 10m1/kg and a rate of 107 breaths/min. ulltil the delivery. Two of 11(18%) patients given O2-N2O alone had recall; none in those patients receiving a potent inhalation agent had any recall. Blood loss was similar in 7tle two groups. There were no statistically significant differences between groups in induction-7odeliverr and uterine incision-t7-delivery intervals, the frequen-cies of Apgar score<7 at and 5 min., maternal and fetal blood 7as tensions, and acid-base balance. 1t is concluded that analgesic concentrations of halothane and enflurane can be safely added to 50% O2-5O% N2O to prevent maternal awareness during general anesthesia for cesarean section while maintaining normal maternal and neonatal conditions.
Acid-Base Equilibrium ; Anesthesia, General ; Cesarean Section* ; Enflurane* ; Female ; Fetal Blood ; Halothane* ; Humans ; Inhalation ; Pregnancy ; Thiopental ; Tidal Volume

Serum IgE levels in 48 patients with scabies were measured by enzyme-linked immunosorbent a.ssay(ELISA) to evaluate the relationship between the scabies and serum IgE. A group of 44 healthy persons was taken as a controls. The results were summarized as follows: In children group(p 15 year-old) of the scabies, serum IgE level was 446 3 +267.2 IU/ml and significantly elevated than in controls, 126, 3 175, 4 IU/rnl, In adult group(over 16 year-old), serum IgE levels of the scabies and controls were 506. 4 + 581. 8 IU/ml, 435, 5+ 548, 8 lU/rnl respetively, and there was no significant difference between them. 2) There were no statistical correlations between the serum IgE levels and intensity of pruritus, duration of illness, number of skin lesions or number of circu1ating eosinophils in patients with scabies.
Adult ; Child ; Eosinophils ; Humans ; Immunoglobulin E* ; Pruritus ; Scabies* ; Skin

Effects of nitroglycerin (NTC), adenosine triphosphate (ATP) and sodium nitroprusside (SNP) on the hemodynamic and blood gas analysis changes epinephrine (EPI) infusion is air embolized cats were investigated. Under the general anesthesia with pentobarbital and vecuronium cats were given 2~2.5 ml/kg of air via internal jugular vein and were resuscitated with EPI bolus injection. Thirty two cats were divided into 4 groups of 8 each. Each 4 groups, were administered saline (group1), NTG (group 2), ATP (group 3) and SNP (group 4) with EPI continuous infusion, respectively. The air shadow in the heart of cats was visualized C-arm image intensifier throught the study and all three vasodilators augmented the removal of air from the heart on C-arm image. All three vasodilators therapy groups produced statistically significant decrease in rate pressure product (p<0.05) but only NTG therapy group decreased heart rate (p<0.05). Central venous pressure were decreased in all three vasodilators therapy groups but only NTG therapy group was statistically significant (p<0.05). Only NTG therapy group increased both arterial (p<0.05) and venous oxgenation. These results indicate that NTG therapy group produced more prominant hemodynamic and blood oxygenation improvement than the other three groups. It is concluded that NTG with vasopressor therapy coude be recommended in venous air embolism.
Adenosine Triphosphate* ; Adenosine* ; Anesthesia, General ; Animals ; Blood Gas Analysis* ; Cats* ; Central Venous Pressure ; Embolism, Air ; Epinephrine* ; Heart ; Heart Rate ; Hemodynamics* ; Jugular Veins ; Nitroglycerin ; Nitroprusside* ; Oxygen ; Pentobarbital ; Sodium* ; Vasodilator Agents ; Vecuronium Bromide

Effects of nitroglycerin (NTC), adenosine triphosphate (ATP) and sodium nitroprusside (SNP) on the hemodynamic and blood gas analysis changes epinephrine (EPI) infusion is air embolized cats were investigated. Under the general anesthesia with pentobarbital and vecuronium cats were given 2~2.5 ml/kg of air via internal jugular vein and were resuscitated with EPI bolus injection. Thirty two cats were divided into 4 groups of 8 each. Each 4 groups, were administered saline (group1), NTG (group 2), ATP (group 3) and SNP (group 4) with EPI continuous infusion, respectively. The air shadow in the heart of cats was visualized C-arm image intensifier throught the study and all three vasodilators augmented the removal of air from the heart on C-arm image. All three vasodilators therapy groups produced statistically significant decrease in rate pressure product (p<0.05) but only NTG therapy group decreased heart rate (p<0.05). Central venous pressure were decreased in all three vasodilators therapy groups but only NTG therapy group was statistically significant (p<0.05). Only NTG therapy group increased both arterial (p<0.05) and venous oxgenation. These results indicate that NTG therapy group produced more prominant hemodynamic and blood oxygenation improvement than the other three groups. It is concluded that NTG with vasopressor therapy coude be recommended in venous air embolism.
Adenosine Triphosphate* ; Adenosine* ; Anesthesia, General ; Animals ; Blood Gas Analysis* ; Cats* ; Central Venous Pressure ; Embolism, Air ; Epinephrine* ; Heart ; Heart Rate ; Hemodynamics* ; Jugular Veins ; Nitroglycerin ; Nitroprusside* ; Oxygen ; Pentobarbital ; Sodium* ; Vasodilator Agents ; Vecuronium Bromide

No abstract available.
Embryonic Structures* ; Humans* ; Upper Extremity*

No abstract available.
Acupuncture ; Sarcoidosis

This study investigated the effects of high amylose starch (HAS) consumption on gut functions in male Sprague-Dawley rats. Experimental animals were fed an diet containing HAS for 4 weeks (0, 125, 250, 500 g/kg diet). Stool weights, transit time, the pH of cecum, Bifidobacterium growth, short chain fatty acid production, and prostaglandin E2 production in colon mucus were measured. HAS intake did not affect body weight gain or food efficiency ratio during experimental period. There were no significant differences in kidney weight, epididymal fat pad weights or spleen weights, but the weights of the liver and thymus were significantly lower in the HAS100 group. The length of the large intestine, the weights of the cecum wall and cecum contents, and stool weights significantly increased through HAS intake. But transit time was not affected by the experimental diet. Although Bifidobacterium growth in the cecum increased through the HAS intake dose dependently, there were significant differences in the HAS50 and HAS100 groups. HAS intake increased the production of short chain fatty acid in the cecum contents. In particular, acetate and butyrate concentrations grew significantly. And the production of prostaglandin E2 in the colon mucus significantly decreased through HAS intake. These results demonstrate that high amylose starch intake significantly improves gut function.
Adipose Tissue ; Amylose* ; Animals ; Bifidobacterium ; Body Weight ; Butyrates ; Cecum ; Colon ; Diet ; Dinoprostone ; Humans ; Hydrogen-Ion Concentration ; Intestine, Large ; Kidney ; Liver ; Male ; Mucus ; Rats* ; Rats, Sprague-Dawley ; Spleen ; Starch* ; Thymus Gland ; Weights and Measures