No abstract available.
Acrospiroma* ; Lip

No abstract available.
Endometriosis ; Female ; Leuprolide* ; Pityriasis Rosea*

No abstract available.
Neurofibroma*

OBJECTIVE: The patients of endometriosis may complain of dysmenorrhea, pelvic pain, and dyspareunia, but may be asymptomatic. We studied on the correlation between the pain and the psychologic stress, Also, we studied on the correlation between serum CA-l25 levels and the psychologic stress. METHODS: The data was obtained from il7 endometriosis patients. Psychological stress was studied with STAI(Stait-Trait Anxiety Inventory) and BDI(Beck Depression Inventory). We compared the degree of anxiety and depression according to existence of pain and the duration of pain. Also we examed the scores of STAI and BDI according to the level of serum CA-125. RESULTS: The pain group had more depression and anxiety, in comparison to the pain-free group. And the depression and anxiety significantly increased in long-term pain group. There was no correlation between the level of serum CA-125 and the depression,or axiety. CONCLUSION: The pain of endometriosis may play a role of pychological stress to the patients, so it seems to increase depression and anxiety.
Anxiety ; Depression ; Dysmenorrhea ; Dyspareunia ; Endometriosis* ; Female ; Humans ; Interleukin-7 ; Pelvic Pain ; Stress, Psychological*

One author's affiliation is misspelled in original article.

BACKGROUND: Keratoacanthoma (KA) can be clinically differentiated with ease from other dermatoses. However, the differential diagnosis of KA can sometimes be difficult, and some cases clinically suggest that the results of skin biopsies of lesions thought to be KA indicate other diseases. OBJECTIVE: The purpose of this study is to examine the diagnostic yield in submitting clinically diagnosed KA that showed solitary symmetric, firm, erythematous, or skin-colored nodules. METHODS: We retrospectively reviewed the clinical records of 54 patients with a clinical diagnosis or differential diagnosis of KA who received biopsies and visited the department of dermatology from January 2004 to December 2013. We compared clinical and histopathologic diagnoses and analyzed the rate of concurrence. In addition, clinical features, including age, sex, location, and duration were investigated. RESULTS: Of the patients, 40.7% were clinically diagnosed with KA, but the results of the histopathology tests indicated other diseases. The mean age of the patients with KA was 72.8 years, and the ratio of men to women was 1 : 0.92. Of the new patients, 0.07% had KA, and most of the lesion sites (84.0%) were caused by sun exposure. Other diseases that are more common in patients with KA are squamous cell carcinoma (55.2%), basal cell carcinoma (20.7%), seborrheic keratosis (6.9%), verruca vulgaris (6.9%), pyogenic granuloma (3.4%), clear cell acanthoma (3.4%), and Bowen's disease (3.4%). CONCLUSION: Skin lesions thought to be KA need more examinations, and skin biopsies of appearances of clinically atypical lesions that cannot completely exclude the possibility of precancerous or malignant lesions are strongly recommended.
Acanthoma ; Biopsy ; Bowen's Disease ; Carcinoma, Basal Cell ; Carcinoma, Squamous Cell ; Dermatology ; Diagnosis ; Diagnosis, Differential ; Female ; Granuloma, Pyogenic ; Humans ; Keratoacanthoma* ; Keratosis, Seborrheic ; Male ; Retrospective Studies ; Skin ; Skin Diseases ; Solar System ; Warts

BACKGROUND: Lip skin diseases are common findings in dermatology. However, most dermatologists are not familiar with the clinical features of lip skin diseases due to the special characteristics of the lip. OBJECTIVE: This study aimed to evaluate the clinical and histopathological features of lip skin diseases. METHODS: We retrospectively reviewed 259 patients who underwent biopsy for labial diseases at the Department of Dermatology from January 2002 to December 2011. We compared the clinical and histopathological diagnoses and analyzed the rate of concurrence and labial tumor distribution. In addition, demographic and clinical features, including age, sex, location, and disease duration, were investigated. RESULTS: The mean age of the patients was 56.8 years and the male-to-female ratio was 1:0.77. Lip skin diseases accounted for 4.1% of all new patients during the study period, with the lower lip being the most commonly affected site (88.4%). The most common disease was actinic cheilitis (35.1%), followed by chronic cheilitis (11.6%), mucocele (10.0%), and squamous cell carcinoma (9.7%). The most common type of tumor was actinic cheilitis (54.8%), followed by mucocele (15.7%), squamous cell carcinoma (15.1%), hemangioma (4.2%), pyogenic granuloma (4.2%), keratoacanthoma (1.8%), and basal cell carcinoma (1.2%). Before the patients came to the university hospital, they received medical treatment at various clinics and departments, including dermatology clinics (55.3%), internal medicine (26.2%) and urology departments (10.7%), and general practitioners (9.7%). CONCLUSION: This study provides novel and useful data on the incidence and characteristics of lip skin diseases. Compared to previous studies, the frequency of lip tumors was relatively high and variable in this study. Based on these results, we advise physicians to, if in doubt, initially diagnose and treat for actinic cheilitis and labial tumors (especially squamous cell carcinoma) caused by long term exposure to the sun.
Actins ; Biopsy ; Carcinoma, Basal Cell ; Carcinoma, Squamous Cell ; Cheilitis ; Dermatology ; Diagnosis ; General Practitioners ; Granuloma, Pyogenic ; Hemangioma ; Humans ; Incidence ; Internal Medicine ; Keratoacanthoma ; Lip* ; Mucocele ; Retrospective Studies ; Skin Diseases* ; Solar System ; Urology

No abstract available.
Humans ; Mycosis Fungoides* ; Spondylitis, Ankylosing* ; Infliximab

BACKGROUND: In order to evaluate the prevalence of enterovirus and cytomegalovirus infections to terminally failing hearts, the presence of enteroviral RNA and cytomegaloviral DNA was screened in the explanted hearts of transplantation recipients. METHODS: RNA and DNA extractions were performed from explanted failing hearts (N=22) and normal hearts (N=5). Reverse transcription-polymerase chain reaction (RT-PCR) of enterovirus and polymerase chain reaction (PCR) of cytomegalovirus were performed. In situ RT-PCR and in situ PCR were performed with positive nucleic acids of viruses. RESULTS: The positivity of enterovirus in failing hearts was 4.4% (1/22) and 0% (0/5) in normal hearts in nested RT-PCR. There was no significant difference in positivity of enteroviral RNA between failing and normal hearts. Nuclei of myocardium was stained in dark-violet color with in situ RT-PCR. The positivity of cytomegalovirus in failing hearts was 45% (10/22) and 40% (2/5) in nested PCR. There was no significant difference in positivity of cytomegaloviral DNA between failing and normal hearts. Nuclei of myocardium was stained in dark-violet color with in situ PCR. Positive chambers of cytomegalovirus were in decreasing tendency according to increasing patient's age. CONCLUSION: Enterovirus was very rarely observed in explanted terminally failing hearts and cytomegalovirus was frequently found both in explanted failing hearts and normal. These viruses have little direct causal relationship with the development of heart failure.
Cardiomyopathy, Dilated ; Cytomegalovirus Infections* ; Cytomegalovirus* ; DNA ; Enterovirus* ; Heart Failure ; Heart* ; Humans* ; Mass Screening* ; Myocardium ; Nucleic Acids ; Polymerase Chain Reaction ; Prevalence ; RNA