No abstract available.
Endometriosis ; Female ; Leuprolide* ; Pityriasis Rosea*

No abstract available.
Acrospiroma* ; Lip

No abstract available.
Neurofibroma*

OBJECTIVE: The patients of endometriosis may complain of dysmenorrhea, pelvic pain, and dyspareunia, but may be asymptomatic. We studied on the correlation between the pain and the psychologic stress, Also, we studied on the correlation between serum CA-l25 levels and the psychologic stress. METHODS: The data was obtained from il7 endometriosis patients. Psychological stress was studied with STAI(Stait-Trait Anxiety Inventory) and BDI(Beck Depression Inventory). We compared the degree of anxiety and depression according to existence of pain and the duration of pain. Also we examed the scores of STAI and BDI according to the level of serum CA-125. RESULTS: The pain group had more depression and anxiety, in comparison to the pain-free group. And the depression and anxiety significantly increased in long-term pain group. There was no correlation between the level of serum CA-125 and the depression,or axiety. CONCLUSION: The pain of endometriosis may play a role of pychological stress to the patients, so it seems to increase depression and anxiety.
Anxiety ; Depression ; Dysmenorrhea ; Dyspareunia ; Endometriosis* ; Female ; Humans ; Interleukin-7 ; Pelvic Pain ; Stress, Psychological*

One author's affiliation is misspelled in original article.

BACKGROUND: Keratoacanthoma (KA) can be clinically differentiated with ease from other dermatoses. However, the differential diagnosis of KA can sometimes be difficult, and some cases clinically suggest that the results of skin biopsies of lesions thought to be KA indicate other diseases. OBJECTIVE: The purpose of this study is to examine the diagnostic yield in submitting clinically diagnosed KA that showed solitary symmetric, firm, erythematous, or skin-colored nodules. METHODS: We retrospectively reviewed the clinical records of 54 patients with a clinical diagnosis or differential diagnosis of KA who received biopsies and visited the department of dermatology from January 2004 to December 2013. We compared clinical and histopathologic diagnoses and analyzed the rate of concurrence. In addition, clinical features, including age, sex, location, and duration were investigated. RESULTS: Of the patients, 40.7% were clinically diagnosed with KA, but the results of the histopathology tests indicated other diseases. The mean age of the patients with KA was 72.8 years, and the ratio of men to women was 1 : 0.92. Of the new patients, 0.07% had KA, and most of the lesion sites (84.0%) were caused by sun exposure. Other diseases that are more common in patients with KA are squamous cell carcinoma (55.2%), basal cell carcinoma (20.7%), seborrheic keratosis (6.9%), verruca vulgaris (6.9%), pyogenic granuloma (3.4%), clear cell acanthoma (3.4%), and Bowen's disease (3.4%). CONCLUSION: Skin lesions thought to be KA need more examinations, and skin biopsies of appearances of clinically atypical lesions that cannot completely exclude the possibility of precancerous or malignant lesions are strongly recommended.
Acanthoma ; Biopsy ; Bowen's Disease ; Carcinoma, Basal Cell ; Carcinoma, Squamous Cell ; Dermatology ; Diagnosis ; Diagnosis, Differential ; Female ; Granuloma, Pyogenic ; Humans ; Keratoacanthoma* ; Keratosis, Seborrheic ; Male ; Retrospective Studies ; Skin ; Skin Diseases ; Solar System ; Warts

No abstract available.
Humans ; Mycosis Fungoides* ; Spondylitis, Ankylosing* ; Infliximab

BACKGROUND: A medulloblastoma is a primitive neuroepithelial tumor of the cerebellum that occurs in children and metastasizes through the cerebrospinal fluid. It is highly malignant and invasive, and the 5-year survival rate is only 60%. Surgical resection techniques, radiation, and chemotherapy have improved the overall survival but the patients suffer life-long cognitive dysfunctions or endocrine abnormalities as the side effects of treatment. Therefore it is essential to identify prognostic markers to determine the appropriate treatment strategy in order to minimize the side effects. METHODS: This study evaluated the immunohistochemical differentiation and survival rate with synaptophysin, glial fibrillary acidic protein, epithelial membrane antigen, vimentin and primitive neuroepithelial marker nestin of 55 paraffin-embedded medulloblastomas, using a tissue microarray. The expression of survivin, the apoptotic inhibitor, and the survival rate with regard to the proliferation index of Ki-67 were also investigated. RESULTS: The group testing positive to vimentin, a mesenchymal differentiation marker, had a worse prognosis and there was a strong correlation between vimentin expression and nestin expression. Patients with a survivin expression rate >35% had a significantly poorer clinical course and there was a correlation between the survivin expression rate and Ki-67 expression rate. CONCLUSION: In conclusion, vimentin and survivin are negative prognostic markers in medulloblastomas.
Cerebellum ; Cerebrospinal Fluid ; Child ; Drug Therapy ; Glial Fibrillary Acidic Protein ; Humans ; Medulloblastoma* ; Mucin-1 ; Nestin ; Neuroectodermal Tumors, Primitive ; Prognosis ; Survival Rate ; Synaptophysin ; Vimentin*

No abstract available.
Foot* ; Neuroma*