It has been reported that the cause of the bacterial endophthalmitis following cataract extraction and intraocular lens implantation was G(+) organisms in most cases. However, the endophthalmitis caused by G(-) organisms has worse prognosis than that by G(+)organisms. We experienced a case of Stenotrophomonas maltophilia endophthalmitis which has not yet been reported in Korea. A 77-year-old female presented with blurred vision, conjunctival injection and ocular pain 5 days after cataract extraction and intraocular lens implantation. Ocular findings such as corneal edema, hypopyon and thick posterior capsular opacity were consistent with infectious endophthalmitis. Culture of vitreous aspirate isolated Stenotrophomonas maltophilia 15 days after cataract extraction.
Aged ; Cataract Extraction ; Cataract* ; Corneal Edema ; Endophthalmitis* ; Female ; Humans ; Korea ; Lens Implantation, Intraocular ; Prognosis ; Stenotrophomonas maltophilia* ; Stenotrophomonas*

Verrucous hyperplasia of the distal stump skin is a rare condition which shows multiple, irregular warty papules and plaques but histologically no evidence of viral warts. It has been suggested that verrucous hyperplasia results from persistent stump edema, usually when the distal stump is unsupported in the prosthesis socket. We present a 53-year-old male who showed verrucous plaques on the distal stump skin and also showed edematous change with oozing. He has been wearing a below-the-knee prosthesis for 35 years since a traumatic amputation and has not changed the prosthesis for 30 years. Histopathological findings showed hyperkeratosis, parakeratosis, acanthosis, papillomatosis, dermal edema, fibrosis, dermal vessel proliferation and dilatation. He was diagnosed as having verrucous hyperplasia with lymphedema by clinical and histopathological findings.
Amputation ; Amputation, Traumatic ; Amputees* ; Dilatation ; Edema ; Fibrosis ; Humans ; Hyperplasia* ; Lymphedema* ; Male ; Middle Aged ; Papilloma ; Parakeratosis ; Prostheses and Implants ; Skin ; Warts

Several conditions such as nipple eczema, erosive adenomatosis of the nipple, mammary Paget's disease and hyperkeratosis of the nipple and areola occur exclusively in the region of the areola and nipple. Seborrheic keratosis is a benign epidermal lesion that can appear on any part of the body but reported cases appearing on the areola are very rare. Cutaneous horn generally presents as an asymptomatic, conical keratotic mass, which commonly occurs on sun-exposed skin, and has an underlying condition that may be benign, premalignant, or malignant. Seborrheic keratosis is a well known benign underlying condition of the cutaneous horn. We herein present a 49-year-old male with a conical hyperkeratotic mass on his right areola, which, upon microscopic examination was revealed to be seborrheic keratosis.
Animals ; Eczema ; Horns* ; Humans ; Keratosis, Seborrheic* ; Male ; Middle Aged ; Nipples ; Paget's Disease, Mammary ; Skin

Metric dimensions of skull of Korean adults were measured and the indices of each dimension were calculated to identify the morphological characteristics of neurocrania of Koreans in 97 cases. The results were as follows. The maximal anteroposterior length was 171.6±8.4 (149.0~191.0)mm and the maximal lateral length (maximal breadth) was 142.4±5.4 (128.0~155.0)mm. The horizontal cranial index was 83.3±5.0 and therefore the neurocrania of Koreans were classified to brachycranic type (rounded cranium). The auriculo-bregmatic height was 119.3±5.1mm and basio-bregmatic height was 140.5±4.9mm. The height-breadth index on the basis of the auriculo-bregmatic height was 98.5±3.6, and belong to medium skull. The height-length index was 81.8±3.8, therefore they belonged to high skull. Height-breadth index on the basis of auliculo-bregmatic height was 85.4±5.7, and belonged to medium skull, and the height-length index was 70.5±5.4 and belonged to high skull. In the case of mean height index, the auriculo-bregmatic height was 77.2±5.0 (high skull), basio-bregmatic height was 87.6±2.6 (high skull).
Adult* ; Humans ; Skull

BACKGROUND: Multiple sclerosis (MS) is a demyelinating disease of the central nervous system. Secondary amyloidosis can occur as a complication of chronic systemic inflammatory and infectious diseases. Until now there has been no report of secondary amyloidosis associated with MS. We report herein a case of renal biopsy-proven secondary amyloidosis in a patient with MS. CASE REPORT: A 41-year-old woman with MS was hospitalized due to aggravated quadriparesis and edema in both lower extremities. Laboratory findings showed nephrotic-range proteinuria and hypoalbuminemia. A percutaneous renal biopsy procedure was performed, the results of which revealed secondary amyloid-A-type amyloidosis associated with MS. CONCLUSIONS: This is the first report of secondary amyloidosis associated with MS.
Adult ; Amyloidosis ; Biopsy ; Central Nervous System ; Communicable Diseases ; Demyelinating Diseases ; Edema ; Female ; Humans ; Hypoalbuminemia ; Lower Extremity ; Multiple Sclerosis ; Nephrotic Syndrome ; Proteinuria ; Quadriplegia

An ectopic pancreas, also known as a heterotopic or aberrant pancreas, is defined as pancreas tissue lying outside its normal location and lacking anatomic or vascular connections with the pancreas. Most occurrences of an ectopic pancreas are located in the stomach, duodenum, or jejunum. However, an ectopic pancreas can sometimes be found in unusual sites such as the Meckel's diverticulum, gallbladder, umbilicus, mediastinum and fallopian tubes. An ectopic pancreas rarely produces clinical symptoms, but occasionally can result in varying symptoms according to its location, size and involvement of the overlying mucosa. Herein, a case of 41-year-old male with an ectopic pancreas in the duodenum, presenting as a duodenal obstructing mass, is reported.
Adult ; Deception ; Duodenum ; Fallopian Tubes ; Female ; Gallbladder ; Humans ; Jejunum ; Male ; Meckel Diverticulum ; Mediastinum ; Mucous Membrane ; Pancreas* ; Stomach ; Umbilicus

Pilomatricoma, also known as the calcifying epithelioma of Malherbe, is a benign adnexal neoplasm that arises from primitive cells of the hair matrix. It usually appears as a firm, slowly growing dermal or subcutaneous nodule, almost solitary but occasionally multiple. Anetoderma is characterized clinically by discrete, atrophic skin lesions and pathologically by the focal loss of elastic fibers in the dermis. Anetodermic cutaneous changes in the skin overlying a pilomatricoma have been rarely described in the literature. Herein, we report 17-year-old girl who presented with two skin lesions, one of which was a painful nodule with bag-like, wrinkled surface on the left posterior shoulder and the other was asymptomatic deep seated nodule with skin colored surface on the left upper back. The histopathologic examination showed typical findings of pilomatricoma, and anetoderma was associated with tender nodule on the shoulder.
Adolescent ; Anetoderma* ; Dermis ; Elastic Tissue ; Female ; Hair ; Humans ; Pilomatrixoma* ; Shoulder ; Skin

PURPOSE: Hypoxia can impair the therapeutic efficacy of radiotherapy (RT). Therefore, a new strategy is necessary for enhancing the response to RT. In this study, we investigated whether the combination of nanoparticles and RT is effective in eliminating the radioresistance of hypoxic tumors. MATERIALS AND METHODS: Gold nanoparticles (GNPs) consisting of a silica core with a gold shell were used. CT26 colon cancer mouse model was developed to study whether the combination of RT and GNPs reduced hypoxia-induced radioresistance. Hypoxia inducible factor-1α (HIF-1α) was used as a hypoxia marker. The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay and terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) staining were conducted to evaluate cell death. RESULTS: Hypoxic tumor cells had an impaired response to RT. GNPs combined with RT enhanced anti-tumor effect in hypoxic tumor compared with RT alone. The combination of GNPs and RT decreased tumor cell viability compare to RT alone in vitro. Under hypoxia, tumors treated with GNPs + RT showed a higher response than that shown by tumors treated with RT alone. When a reactive oxygen species (ROS) scavenger was added, the enhanced antitumor effect of GNPs + RT was diminished. CONCLUSION: In the present study, hypoxic tumors treated with GNPs + RT showed favorable responses, which might be attributable to the ROS production induced by GNPs + RT. Taken together, GNPs combined with RT seems to be potential modality for enhancing the response to RT in hypoxic tumors.
Animals ; Anoxia ; Cell Death ; Cell Survival ; Colonic Neoplasms ; DNA Nucleotidylexotransferase ; In Vitro Techniques ; Mice ; Nanoparticles* ; Radiotherapy* ; Reactive Oxygen Species ; Silicon Dioxide

Prurigo pigmentosa is a rare inflammatory dermatosis of unknown etiology characterized by recurrent, pruritic, erythematous papules with gross reticulate hyperpigmentation. The cause of prurigo pigmentosa is unknown. Exogenous factors, fasting, dieting, ketosis, diabetes mellitus and pregnancy have been reported to be associated with prurigo pigmentosa. We now present two cases of prurigo pigmentosa associated with dieting. These findings suggest that the ketosis produced by dieting may well contribute to the pathogenesis of prurigo pigmentosa.
Diabetes Mellitus ; Diet ; Fasting ; Hyperpigmentation ; Ketosis ; Pregnancy ; Prurigo* ; Skin Diseases

A pancreatic hamartoma is a rare benign lesion that may be mistaken for malignancy. A pancreatic hamartoma can present with vague, non-specific symptoms, which can be difficult to diagnose despite modern diagnostic tools. We report here a pancreatic hamartoma diagnosed after surgical resection. A 52-year-old female presented with postprandial abdominal discomfort. Abdominal computed tomography and pancreatic magnetic resonance imaging revealed a 2.2 x 2.5-cm cystic mass in the pancreatic head. The patient underwent a pylorus-preserving pancreaticoduodenectomy. The histopathological and immunohistochemical studies helped make the diagnosis of pancreatic hamartoma. Here, we report a case of pancreatic hamartoma and review the relevant medical literature.
Female ; Hamartoma ; Head ; Humans ; Magnetic Resonance Imaging ; Middle Aged ; Pancreas ; Pancreaticoduodenectomy