From the leprosy patients hospitalized at the Korean National Leprosarium on Snrokdo Island, forty-five leprosy patients with plantar ulcers were selected randomly for microbiological studies. A total of 84 strains of bacteria, with the most common being Neieseria sicca (25 strains: 29.8%), 34 strains (40. 5%) were present as a pure growth and 50 strains (59. 5%) were present in ulcers with multiple infection. Antibiotic susceptibility tests indicated that bacterial isolates were rather highly susceptible to gentarnicin and kanamycin, but varying degree of isolates were resistant to 12 antibiotics including streptomycin, rifampicin, lincomycin, penicillin, terramycin and colimycin etc. From a total of 30 plantar ulcers, 17 ulcers produced 24 strains of fungi and 1 strain of Balanticlium coli. They consisted of 17 strains of saprophytic fungi (70. 8%) and 7 strains of yeast-like fungi (29. 2%). Of the culture media for Balantidium coli, Sabourauds glucos medium is the most specific and selective that the author found.
Anti-Bacterial Agents ; Bacteria ; Balantidium ; Colistin ; Culture Media ; Foot Ulcer* ; Fungi ; Humans ; Kanamycin ; Leprosy* ; Lincomycin ; Oxytetracycline ; Penicillins ; Rifampin ; Streptomycin ; Ulcer

No abstract available.

I tried the endoscopic laser therapy for the malignant and benign disease of the alimentary tract to evaluate efficacy in rejection of surgical treatment or inoperable state. I have experienced 16 cases of the laser therapy in my hospital from July 1990 to June 1991. The apparatus I used is the SLT contact Nd-YAG laser with the ceramic endoprobe of rounded or chisel or hollow type in each case. The irradiation was made at an output of 15-20 Watts within 1.5 seconds. Between the 2-4 weeks laser therapy, the treatment response was observed by rebiopsy, I treated 7 cases of early gastric cancer and post-laser follow-up study showed 70% negative for cancer cells by endoscopic biopsy. Failure of laser treatment was found in case of IIc type, Two cases of advanced gastric and I case of rectal cancer with severe obstruction were relieved by laser therapy. I also experienced 3 cases of esophageal or gastric polyp which were completely. resolved after irradiation. Besides, I could get hemostasis in 1 case of gastric ulcer bleeding with exposed vessels and 1 case of Mallory-Weiss syndrome. And a case of gastric bezoar was completely fragmentated after irradiation. As mentioned above, I achieved satisfactory results of 13 cases in 16 cases. Contact Nd - YAG laser treatment ean be applicated with excellent efficacy in any age, sex and severity of disease with or without complications and any site of lesions which can be reached within the endoscope. I suggest it is maybe highly promising medical technique in the future.
Bezoars ; Biopsy ; Ceramics ; Endoscopes ; Follow-Up Studies ; Hemorrhage ; Hemostasis ; Laser Therapy* ; Lasers, Solid-State ; Mallory-Weiss Syndrome ; Polyps ; Rectal Neoplasms ; Stomach Neoplasms* ; Stomach Ulcer

No abstract available.
Hypertension, Renovascular*

No abstract available.

No abstract available.

To develop the polymerase chain reaction (PCR) for the detection of type D simian retrovirus (SRV) infection, an oligonucleotide primer pair was designed to hybridize to the sequences within euv gene of SRV subtype 1 (SRV-1). The 3'proximal env sequences annealing to the primers had been rather conserved among three different subtypes of SRV, SRV-1, SRV-2, and SRV-3 (Mason-Pfizer Monkey Virus: MPMV). The PCR using the primer pair targetingan an env region the successfully detected and amplified all three subtypes of SRV with excellent specificity after single round of reaction. The tests with peripheral blood mononuclear cells infected either with simian immunodeficiency virus or simian T-lymphotropic virus type 1, maior immunosuppressive viral agents together with SRV in simian, verified the specificity of the PCR by excluding any cross reactivity. Semiquantitative titration PCR, amplifying serially diluted plasmid DNA of each subtype, was performed to evaluate sensitivity limits of the reaction. Based on molecular weight of each cloned SRV genome, the PCR should be able to detect one SRV-infected cell per more than 5-7x104 uninfected cells after simple ethidium bromide staining of resulting products. The PCR must be very efficient screening sisters with its quickness, certainty, and sensitivity for SRV-infected animals used in human AIDS research model. Second round amplification of the reaction products from the first PCR, or Southern hybridization by radiolabeled probes shall render to compete its efficacy to ELISA which has been the most sensitive technique to screen SRV infection but with frequent ambiguity problem.
Animals ; Betaretrovirus* ; Clone Cells ; DNA* ; Enzyme-Linked Immunosorbent Assay ; Ethidium ; Genome ; Haplorhini ; Humans ; Mason-Pfizer monkey virus ; Mass Screening ; Molecular Weight ; Plasmids ; Polymerase Chain Reaction* ; Retroviruses, Simian ; Sensitivity and Specificity ; Siblings ; Simian Immunodeficiency Virus

Indications of reverse total shoulder arthroplasty (RTSA) have been consistently extended by technical advancements in reverse arthroplasty prosthesis, continuous development of the implants, accumulated experiences and its successful treatment outcomes; accordingly, its use has rapidly increased. RTSA has been performed for a variety of indications, with variable outcomes depending on the initial diagnosis. However, controversial opinions still exist regarding the design of reverse arthroplasty prosthesis (medialized or lateralized design and the neck-shaft angle of the humeral prosthesis), suture of the subscapularis tendon, use of cement during placement of the humeral prosthesis, and surgical procedures; therefore, these should be investigated so that they can be better understood.
Arthroplasty* ; Diagnosis ; Prostheses and Implants ; Shoulder* ; Sutures ; Tendons

It has passed 20 years since the first conference of the Korean Psychosomatic Society(KPMS) had been held. Therefore, it seems that it is the appropriate time to evaluate the current status and to look back the history of the Korean psychosomatic medicine in three aspects, clinical treatment, education, and research, and to make a plan for the future. Of the three areas, the clinical practice of Korean psychosomatic medicine will be discussed. As the past, I reviewed the historical background and development of KPMS, and the proposals presented at the first conference of KPMS in 1992. As the present, I presented the short stories about the psychosomatic clinic in Japan, Germany, and USA, to compare it with the present status of Korean one. And finally I made careful proposals for the future of the Korean psychosomatic medicine.
Germany ; Japan ; Korea ; Psychosomatic Medicine

BACKGROUND: Although there were many studies about increasing the bone mineral density(BMD) of the elderly by exercise program, the results of weekly exercise participation degree are still to be not prepared. Therefore I examined that the effect of weekly exercise participation degree on BMD level of the elderly. METHODS: Subjects were 93 older adults (male=43, female=50) residing in Seoul-Seniors-To-wei. These people are either participating in exercise program for a year, or not in Song-Do Hospital Exercise Prescription Center. Among the elderly, if one were took part in exercise program 5 days or more weekly, they are classified in Group A(male = 14, female= 14), if one were took part in exercise program 5 days weekly, they are classified in Group B (male = 14, female = 17), if one were took part in exercise program a day weekly. they are classified in Group C(mal =8, female= 13). and if one were not took part in exercise program, they are involved in Group I)(male=7, female=6). All the measured data were represented by mean and standard deviation using SPSS package(ver10.0). The statistical techniques for data analysis of BMD levels of the four groups in male and female groups were to analyze the differences among groups by one way ANOVA. And then I performed the Scheffe post-hoc method forinvestigating exactly the differences among groups. The 5% level of significance was used as the critical level for acceptance of hypotheses for the study. RESULTS: There were no statistical difference (p>0.05) among four male or female groups in BMD levels of head, anus, trunk, ribs, and pelvis parts. But there were statistical differences(p <0.05) among four male or female groups in BMD levels of legs, spine, and total. On the condition of legs, the BMD level of Group A exercised in 5 days or more weekly was 1.58 g/cm2 (F=6.774, p=0.001) in male groups and 1.17 g/cm2 (F =6.616. p=0.001) in female groups. These levels were the highest among four groups. And on the condition of spine, the BMD level of Group A was 1.17 g/cm2(F=7.732, p=0.001) in male groups and 1.16 g/cm2(F=6.243, p=0.002) in female groups. These levels were the highest among four groups. Also on the cutiditiuii of total, the BMD level of Group A was 1.53 g/cm2(F=5.677, p=0.003) in male groups and 1.1 g/cm(F=5.283, p=0.003)in female groups. These levels were the highest among four groups. CONCLUSION: Although the exercise is advantageous to the elderly people, if they are participated in 5 days or more weekly, they will be gained more benefit on BMD level and so on.
Adult ; Aged* ; Anal Canal ; Bone Density* ; Female ; Head ; Humans ; Leg ; Male ; Pelvis ; Prescriptions ; Ribs ; Spine ; Statistics as Topic