Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is characterized histologically by massive infilteration of right ventricular wall by fat tissue with surviving strands of cardiomyocytes bordered by or embedded in fibrosis. ARVC has been recognized as a cause of sudden death, especially in the young. We report an autopy case of ARVD/C in a 35-year-old female. She was found dead in her house under apparently natural circumstances. The autopsy revealed a dilated 340-gram heart with a fibrofatty replacement of the right ventricular myocardium. On the review of her past medical history, she had taken medical examination for prolonged general weakness about 1 year prior to death. At that time the echocardiogram revealed dilatation of right ventricular cavity size and moderately decreased left ventricular systolic function, the electrocardiogram revealed R>S at V1 lead and T-wave inversion at V1-V3 leads. To the best of our knowledge, this is the second autopsy case of ARVD/C, reported in the literature of Korea.
Adult ; Autopsy* ; Death, Sudden ; Dilatation ; Electrocardiography ; Female ; Fibrosis ; Heart ; Humans ; Korea ; Myocardium ; Myocytes, Cardiac

No abstract available.
Carcinoma, Adenosquamous* ; Lung*

No abstract available.
Adenocarcinoma* ; Scrotum* ; Stomach Neoplasms*

This statistical analysis of 4,709 legal autopsies performed in Korea in 2012 was conducted to obtain primary data about and related variables. The analysis revealed the following: 1. Of the total number of deaths, men accounted for and women, 26.8%. Evidently, the number of deaths among men was more than twice that among women. 2. With respect to mode of death, 54.8% were recorded as unnatural deaths, 39.2% were natural deaths, and 6.0% had unknown causes. Of the 2,581 unnatural deaths, 44.8% were accidental deaths; 27.2%, suicidal; 17.5%, homicidal; and 10.3%, undetermined. 3. Of the total number of unnatural deaths, 43.0% were trauma-related deaths, for which falling down was the leading cause, accounting for 33.5% cases. Asphyxiation was accounted for 17.2%, among which the predominant cause was hanging (55.3%). Moreover, 12.5% of deaths were due to drowning; 11.5%, poisoning; 11.2%, thermal injuries; 2.7%, complications in medical procedures; and 0.3%, electrocution, starvation, or neglect. 4. Among 1,847 natural deaths, heart diseases accounted for 50.2% and vascular diseases accounted for 16.7%. 5. There were 207 cases of deaths among children under the age of 10, of which 94 were unnatural and 49 were homicidal deaths. Of all cases, 9.2% had an unknown cause of death, and of these 67.6%, were putrefied or skeletonized bodies.
Autopsy* ; Cause of Death ; Child ; Drowning ; Female ; Heart Diseases ; Humans ; Korea* ; Male ; Poisoning ; Skeleton ; Starvation ; Vascular Diseases

PURPOSE: We evaluated the rate of prostate cancer detection according to the region and number of biopsies in patients with an elevated level of serum prostate-specific antigen (PSA). MATERIALS AND METHODS: Transrectal ultrasound (TRUS) guided prostate biopsies were performed at 12 regions, using the standard sextant, with an additional 6 cores far lateral peripheral zone, in 178 men with an elevated PSA level, and with no suspicious lesions of prostate cancer on digital rectal examination (DRE) and TRUS. We analyzed the rate prostate cancer detection according to the region, number of biopsies, the PSA level, prostate volume and PSA density (PSAD). RESULTS: The rates of cancer detection were 12.9, 11.8 and 7.4% in the 12 core, lateral 6 core and medial 6 core (standard sextant) biopsies, respectively (p<0.05). There were no differences in overall cancer detection rates between 12 core and lateral 6 core plus apex medial 2 core biopsies (12.9%). In men with a PSA level greater than 20ng/ml, no difference in cancer detection was found with the 12 core or either of the 6 core biopsies (positive rate 33.3%). In men with a PSA level over 10ng/ml, a prostate volume less than 49cc or a PSAD greater than 0.15, a lateral 6 core biopsy made no difference to the diagnosis of prostate cancer compared to a 12 core biopsy. CONCLUSIONS: A lateral 6 core biopsy, combined with an apex medial 2 core biopsy, is a more efficient method for the detection of prostate cancer than the standard sextant biopsy in men with an elevated serum PSA level without a suspicious lesion on DRE and TRUS.
Biopsy* ; Diagnosis ; Digital Rectal Examination ; Humans ; Male ; Prostate* ; Prostate-Specific Antigen ; Prostatic Neoplasms* ; Ultrasonography

No abstract available.
Biopsy*

Kaposis sarcoma is well recognized in patient,s with imrnunodef cienicy states such as organ trans plantation, malignancy, and acquired irnmunodeficiency syndrome(tILS). Kaposis sarcorna associated with organ transplantation is, however relatively uncomrnon in Konea. We report a case of Kaposi's sarcorna in a 23 year old male kidney recipient., who was on cyclosporine and prednisolone. The tumor involved the larynx and long as well as the skin. He was treated with radiation therapy and chemotherapy, and the dosage of immunosupressants were reduced.
Cyclosporine ; Drug Therapy ; Humans ; Kidney Transplantation* ; Kidney* ; Larynx ; Male ; Organ Transplantation ; Prednisolone ; Sarcoma, Kaposi* ; Skin ; Transplants ; Young Adult

We present a case of dermatomyositis associated with small cell lung cancer. This 45-year-old male patient who had been diagnosed as small cell lung cancer presented multiple itchy violaceous patches, muscle weakness, myalgia and abnormal laboratory data. The skin lesions and myalgia were improved after treatment with dexamethasone 10mg/day under the diagnosis of dermatomyositis. The skin symptoms and myalgia were wax-and-waned despite of the improvement of lung cancer. Interestingly, telangiectasias observed on the proximal nail folds were wax-and-waned according to the skin and muscle symptoms, too. Further evaluation on the finding would be beneficial in the prognosis evaluation for the patients.
Capillaries* ; Dermatomyositis* ; Dexamethasone ; Diagnosis ; Humans ; Lung Neoplasms ; Male ; Middle Aged ; Muscle Weakness ; Myalgia ; Prognosis ; Skin ; Small Cell Lung Carcinoma* ; Telangiectasis

STUDY DESIGN: A retrospective study was designed to evaluate the radiographic diagnostic method to detect any abnormal findings and differentiate stable burst fractures with compression fractures at thoracolumbar spine. OBJECTIVES: To evaluate diagnostic sensitivity of radiographic analysis and confirm the effectiveness of the radiographic diagnostic methods to differentiate stable burst fractures with pure compression fractures. SUMMARY OF BACKGROUND DATA: A data showed that the diagnostic sensitivity using radiographic analysis was 83%. The greater sensitivity was obtained at high posterior superior vertebral angle and PSVA/PIVA > 1.3. MATERIALS AND METHODS: Thirty-one patients with thoracolumbar spine fractures were evaluate to differentiate stable burst fractures with pure compression fractures. All patients were taken X-ray and CT. The PSVA(Posterior superior vertebral angle), PIVA(Posterior inferior vertebral angle), PSVA/PIVA were checked using lateral plain radiographs during follow-up period, and the final data was analysed using radiological & statistical methods. RESULTS: Middle column failure of stable burst fractures was greatly observed at high PSVA(especially >100degree) and high PSVA/PIVA ratio(> 1.3). CONCLUSION: The radiographic analysis using PSVA(Posterior superior vertebral angle), PIVA(Posterior inferior vertebral angle), PSVA/PIVA might be the one of useful methods to differentiate stable burst fractures with pure compression fractures at thoracolumbar spine during follow-up period.
Diagnosis ; Follow-Up Studies ; Fractures, Compression* ; Humans ; Retrospective Studies ; Spine*

No abstract available.
Liver Transplantation* ; Liver*