1.Significance of arterial ketone body ratio in hepatic resection.
Hong Jin KIM ; Sung Su YUN ; Byung Soo DO ; Woo Seok SEO ; Sun Kyo SONG ; Min Chul SHIM ; Koing Bo KWUN ; Hee Won HAM
Journal of the Korean Surgical Society 1992;43(6):812-819
No abstract available.
2.Two cases of listeria meningitis in patients with SLE.
Sung Kyeong WOO ; Hyeon Ok LIM ; Sang Goon SHIM ; Won Ho SHIN ; Keun Ho KIM ; Jong Yeul HAM ; Jong Seok LEE ; Jin Hak CHOI
Korean Journal of Infectious Diseases 1991;23(3):195-199
No abstract available.
Humans
;
Listeria*
;
Meningitis, Listeria*
3.Refactoring the Code for Visualizing Protein Database Information in a 3D Viewer for Software Reusability.
Yoo Jin CHUN ; Seong Il HAM ; San Duk YANG ; Arang RHIE ; Hyun Seok PARK
Genomics & Informatics 2008;6(1):50-53
We have released five Java Application Programming Interface (API) packages for viewing three-dimensional structures of proteins from the Protein Data Bank. To this end, the user interface of an earlier version has been refactored in an object-oriented fashion, in which refactoring is the process of changing a software system to improve its internal structure, without altering the external behavior. Various GUI design and features have been provided conveniently thanks to the Model-View-Control (MVC)model, which is an architectural pattern used in software engineering. Availability: The source code and API specification can be downloaded from https://sourceforge.net/projects/j3dpsv/.
Computational Biology
;
Databases, Protein
;
Indonesia
;
Proteins
;
Software
4.Refactoring the Code for Visualizing Protein Database Information in a 3D Viewer for Software Reusability.
Yoo Jin CHUN ; Seong Il HAM ; San Duk YANG ; Arang RHIE ; Hyun Seok PARK
Genomics & Informatics 2008;6(1):50-53
We have released five Java Application Programming Interface (API) packages for viewing three-dimensional structures of proteins from the Protein Data Bank. To this end, the user interface of an earlier version has been refactored in an object-oriented fashion, in which refactoring is the process of changing a software system to improve its internal structure, without altering the external behavior. Various GUI design and features have been provided conveniently thanks to the Model-View-Control (MVC)model, which is an architectural pattern used in software engineering. Availability: The source code and API specification can be downloaded from https://sourceforge.net/projects/j3dpsv/.
Computational Biology
;
Databases, Protein
;
Indonesia
;
Proteins
;
Software
5.A Rare Kinky Hair Disease: Menkes Syndrome
Ji Hyuck HONG ; Jun Hyuk CHO ; Sung Jin PARK ; Min Seok HAM ; Soo Hong SEO
Korean Journal of Dermatology 2022;60(1):68-69
no abstract available.
6.Purpura Associated with Onion Extract Consumption
Dongwon LEE ; Sung Jin PARK ; Min Seok HAM ; Ji Hyuck HONG ; Soo Hong SEO
Korean Journal of Dermatology 2020;58(3):217-219
7.Dopamine Concentration and Hemodynamic Effects according to the Methods of Dopamine Dilution.
Jin Hee KIM ; Hee Pyung PARK ; Byung Moon HAM ; Yong Lak KIM ; Yoon Seok JEON ; Jung Hoon SEO
The Korean Journal of Critical Care Medicine 2003;18(1):26-32
BACKGROUND: Incorrect infusion of dopamine can be potentially life threatening. If the actual volume of a 100 ml intravenous bag or bottle used to mix dopamine solutions is greater than the labeled volume, overdilution of dopamine can occur, resulting in ineffective hemodynamic response. To determine the significance of dopamine overdilution induced by the excessive volume, dopamine concentration and hemodynamic effect were compared in the manually mixed dopamine and the manufactured premixed dopamine. METHODS: For 5% dextrose water (D5W) 100 ml intravenous bottle mixed with 160 mg (4 ml) of dopamine (group 1), D5W 96 ml mixed with 160 mg of dopamine (group 2), premixed dopamine with 1.6 mg/ml of concentration manufactured 2 months ago (group 3), premixed dopamine with 1.6 mg/ml of concentration manufactured 6 months ago (group 4), and D5W 100 ml intravenous bottle mixed with 160 mg (4 ml) of dopamine after removal of 4 ml dextrose water (group 5), dopamine concentration was measured by High performance liquid chromatography (HPLC). Hemodynamic data was obtained from 10 mongrel dogs for each group at baseline (T1), 15 minutes after dopamine infusion at a rate of 3 microgram/kg/min (T2), 8 microgram/kg/min (T3), and 15 microgram/kg/min (T4). RESULTS: Dopamine concentrations of group 1, 2, 3, 4, and 5 were 1.51+/- 0.09, 1.60 +/- 0.10, 1.63 +/- 0.06, 1.57+/- 0.08 and 1.57+/- 0.07 mg/ml, respectively. Group 1 showed a significantly low concentration (p< 0.05). There was no significant differences in all hemodynamic data between group 1, 2, 3, and 4. In group 1, however, there was no significant increase in both mean blood pressure at T4 and mixed venous oxygen saturation at T3 compared with T1. CONCLUSIONS: The actual volume of D5W in 100 ml intravenous bottle is greater than the labeled, and therefore can cause significant overdilution of dopamine. Premixed dopamine, however, has the same concentration and hemodynamic effects as the dopamine mixed manually but precisely.
Animals
;
Blood Pressure
;
Chromatography, Liquid
;
Dogs
;
Dopamine*
;
Glucose
;
Hemodynamics*
;
Oxygen
;
Water
8.Validation of Temperature Preservation in Specimen Transportation Systems
Sang Gon LEE ; Aerin KWON ; Seungman PARK ; Soyeon SEO ; Young Jin KIM ; Hyoeun SHIM ; Chorong HAM ; Jae-Seok KIM
Laboratory Medicine Online 2020;10(2):116-124
Background:
Clinical specimens are valuable materials that require a traceable management system. Maintenance of temperature and loss prevention during transport are important for the reliability of the clinical test results. Current transportation systems can suffer from temperature changes and agitation. Quality improvement in this pre-analytic phase is required. This study acquired preliminary data from a newly developed specimen transportation system adopting a real-time temperature monitoring during transportation using temperature sensor and global positioning system to establish appropriate guidelines.
Methods:
Temperature preservation performance was compared between two transportation boxes (newly developed one [A] and conventional one [B]) at exterior temperatures of 35℃ and ?18℃, reflecting the extreme temperature range in Korea. Influences of the temperatures on analytical results of whole blood, serum, plasma, and urine specimens were investigated, as were the effects of vibration.
Results:
The interior temperature of box A measured at multiple sites was maintained within 1.0?9.0℃ at both exterior temperatures. The interior temperature of box B was outside of this range. The analyzed parameters varied comparably with the variations occurring at the recommended and published storage temperature. Vibration affected nonspecific enolase and lactate dehydrogenase.
Conclusions
Temperature preservation and real-time monitoring during specimen transportation are important. The present data highlight the importance of transportation conditions and indicate that laboratories should know the characteristics of temperature changes in their transportation system.
9.A Case of Toxic Hepatitis in a Worker Exposed to a Cleansing Agent Mainly Composed of Methylene Chloride.
Bong Goo HA ; Jin Seok KIM ; Jay Young YU ; Kuck Hyun WOO ; Jung Oh HAM ; Seong Yong YOON ; Yong Seok JANG ; Sang Je JUNG
Korean Journal of Occupational and Environmental Medicine 2004;16(2):210-219
OBJECTIVES: To report a case of toxic hepatitis in a worker exposed to a cleansing agent mainly composed of methylene chloride. METHODS: A 27-year-old female worker who had worked in an inspection and packing position of semiconductor parts in a factory using methylene chloride as a metal cleansing solvent was hospitalized due to fever, chill and generalized aches. We evaluated her with blood tests, abdominal ultrasonographic scan and abdominal CT scan and also took her occupational history. RESULTS: The patient showed acute hepatitis in blood and radiologic tests after admission. The serologic tests for viral hepatitis A, B, C and autoimmune hepatitis were negative. She had no history of significant alcohol use, recent medication or drug allergy. After admission, her symptoms were improved and liver enzyme levels(AST and ALT) were markedly reduced. She returned to her workplace after discharge. Thereafter, however, her previous symptoms were recurred and she was hospitalized again 2 days after returning to her workplace. After this second admission, she showed acute hepatitis in blood tests and her symptoms were improved and liver enzyme levels were markedly reduced with the same pattern as those of the first admission. On the 11th day of the second admission, liver enzyme levels were normalized and she was discharged from hospital. CONCLUSIONS: We presume that this patient`s liver injury was related to the methylene chloride presence at her workplace due to her clinical symptoms, blood tests, radiologic tests and occupational history.
Adult
;
Detergents*
;
Drug Hypersensitivity
;
Drug-Induced Liver Injury*
;
Female
;
Fever
;
Hematologic Tests
;
Hepatitis
;
Hepatitis A
;
Hepatitis, Autoimmune
;
Humans
;
Liver
;
Methylene Chloride*
;
Semiconductors
;
Serologic Tests
;
Tomography, X-Ray Computed
10.A Case of Symptomatic Tracheal Diverticulum and Surgical Resection as a Treatment Modality.
Shin Young LEE ; Seok JOO ; Geun Dong LEE ; Seok Jin HAM ; Chul Hwan PARK ; Sungsoo LEE
The Korean Journal of Thoracic and Cardiovascular Surgery 2016;49(5):405-407
Tracheal diverticulum is often diagnosed incidentally and, due to its rarity, there is no standard treatment. It is a benign entity, but has the potential to cause specific symptoms, such as chronic upper respiratory infection and chronic cough. Symptomatic tracheal diverticulum can be medically treated, but likelihood of recurrence is high. We report a case of surgical resection of symptomatic tracheal diverticulum to prevent recurrence.
Cough
;
Diverticulum*
;
Recurrence