1.A Case of Cavernous Type of Angioleimyoma Occurring on the Buttock.
Jae Wang KIM ; Sang Seok KIM ; Kwang Joong KIM ; Chong Ju LEE ; Hyeong Sik SHIN
Annals of Dermatology 1999;11(1):33-36
Angioleiomyoma(ALM) of the cavernous type is a rare subtype of leiomyomas arising from the smooth muscle of veins. ALM of this type invariably shows clinically and histopathologically distinctive features, compared with the classical solid or venous type. However, no case of ALM of this type has been yet reported in Korea although there have been several reported cases of other types. We herein present the case of a 39-year-old man with a 7-year history of a painless ALM of the cavernous type on his buttock with the histological features of markedly ectatic vascular channels and thin intervascular bundles of smooth muscles.
Adult
;
Angiomyoma
;
Buttocks*
;
Humans
;
Korea
;
Leiomyoma
;
Muscle, Smooth
;
Veins
2.A Case of palisaded, Encapsulated Neuroma.
Seok Jin HONG ; Sam Hyeong KIM ; Hoon KANG ; Sook Ja SON ; Hee Jin JANG
Korean Journal of Dermatology 1998;36(1):173-176
Palisaded, encapsulated neuroma is characterized clinically by a solitary, slowly-growing and dome-shaped papule or nodule, usually accompanied by telangiectasia on the surface, and histopathologically by an encapsulated nodule in the dermis and the palisading arrangement of nuclei. A 57-year-old female patient presented with a 1cm-sized, solitary nodule on the right ala nasi which had been present for about 5 years. The nodule had a tendency to slow growth and it became a polypoid nodule. Telangiectasia was shown on the surface of the lesion. Histopathlogical findings showed a well-defined and encapsulated nodule in the dermis, composed of spindle cells with basophilic and plump nuclei in a palisading fashion. On immunohistochemical staining, the tumor cells of the nodule were positive for S-100 protein, while the capsule of the nodule was negative for S-100 protein. Epithelial membrane antigens were focally positive only on the capsule of the nodule. We report herein a case of palisaded, encapsulated neuroma, one case of which has been reported in Korea.
Basophils
;
Dermis
;
Female
;
Humans
;
Korea
;
Middle Aged
;
Mucin-1
;
Neuroma*
;
S100 Proteins
;
Telangiectasis
3.Observations on the Grouping Pattern of Scalp Hairs and Compound Hair in a Normal healthy Population.
Seok Jong LEE ; Do Won KIM ; Jae Bok JUN ; Sang Lip CHUNG ; Kuk Hyeong LEE
Korean Journal of Dermatology 1994;32(6):998-1004
BACKGROUND: Although one hair usually arises from a single follicular opening in normal healthy subjects, we can see two or more hairs emerging from the single opening through close inspection. The latter is called "compound hair", described by Lowenthal in 1946, however, few reports on this have been made since. Histopatholoigcally two or more hairs which have an independant external root sheath arise from one follicular opening like its clinical appearance. We examined the distribution and density of compound hair in order to define its difference according to anatomical sites and aging process. OBJECTIVE AND METHOD: We counted the number of hairs in the circle(2 cm in diameter) at te frontal, temporal and occipital scalp of 24 old young men(22.5+/-2.0 years old) and 24 old men(64.4+/-12.9 years old), respectively. RESULTS: The summated number of grouped hair, which was mostly regarded at compound hair, was greater in the young group than in old group in the frontal area, but was smaller in young group than in old group in from the temporal and occipital areas. The proportion of grouped hair to total hair in the older group was lower in the frontal area, but higher in the temporal and occipital areas(p<0.05, p<0.01) according to aging process, however, no significant change was seen between the frontal area and the sum of single hair to compound hair was significantly decreased in the temporal and occipital areas(p<0.05, p<0.01) according to aging process, however, no significant change was seen between the frontal area and the sum of the three tested areas. CONCLUSION: Compound hairs are observed frequently on the scalp of normal healthy subjects and are most frequently seen on the occipital scalp in both of the young and old.
Aging
;
Hair*
;
Scalp*
;
Tuberculosis, Cutaneous
4.A Case of Pseudallescheria boydii Mycetoma.
Sam Hyeong KIM ; Seok Jin HONG ; Hoon KANG ; Sook Ja SON ; Kyae Yong SONG
Korean Journal of Dermatology 1998;36(2):341-345
Pseudallescheria (P.) boydii is a true fungus that is ubiquitous in nature, and has a world-wide distribution. It has been isolated from soil, plant debris, polluted water and sewage. Infection may occur via direct inoculation or inhalation, and usually affects the extremities. It is a common cause of mycetoma characterized by tumefaction, draining sinuses and grains. It has polymorphism due to a complicated life cycle which undergoes teleomorph as well as anamorph stages. Cleistothecia, ascocarp and ascospore may be seen during the teleomorph stages, whereas scedosporium and graphium type may be seen during the anamorph stages. We report a case of P. boydii mycetoma occurring in a 69-year old male. He had multiple nodules with a discharging fistula on a dark red plaque at the dorsum of the right forearm. Cultural isolation for definitive diagnosis showed typical P. boydii. The lesion responded well to daily itraconazole.
Aged
;
Edible Grain
;
Diagnosis
;
Extremities
;
Fistula
;
Forearm
;
Fungi
;
Humans
;
Inhalation
;
Itraconazole
;
Life Cycle Stages
;
Male
;
Mycetoma*
;
Plants
;
Pseudallescheria*
;
Scedosporium
;
Sewage
;
Soil
6.Treatment of periarticular open fractures of the tibia with ilizarov external fixator.
Kyung Chul KIM ; Sung Joon IM ; Bo Seok KONG ; Bo Hyeong BANG
The Journal of the Korean Orthopaedic Association 1992;27(7):1745-1750
No abstract available.
External Fixators*
;
Fractures, Open*
;
Tibia*
7.Effect of Latanoprostene Bunod on the Permeability of Trabecular Meshwork Cells
Hyeong Seok PARK ; Jae Woo KIM
Journal of the Korean Ophthalmological Society 2024;65(2):139-144
Purpose:
To investigate the effects of latanoprostene bunod (LBN) on nitric oxide (NO) production and permeability in human trabecular meshwork cells (HTMC).
Methods:
HTMC were treated with 50 and 100 µM LBN and latanoprost free acid (LAT) for 30 minutes. Additionally, 100 µM LBN was co-exposed to 0.5 mM L-NAME (N-Nitroarginine methyl ester). Cellular viability and NO production were measured using MTT (3-[4, 5-dimethylthiazol-2-yl]-2, 5-diphenyltetrazolium bromide) and Griess assays. The permeability and resistance of the HTMC monolayer were evaluated by trans-endothelial electrical resistance (TEER) and carboxyfluorescein permeability.
Results:
Exposure to 100 µM LBN led to increased NO production, whereas co-exposure to L-NAME reduced NO production. Treatment with 100 µM LBN decreased the TEER of the HTMC monolayer. LBN exposure heightened carboxyfluorescein permeability, but co-exposure to 100 µM LBN and L-NAME reduced permeability. LAT treatment did not affect NO production or permeability.
Conclusions
LBN increased the permeability of the HTMC monolayer and increased NO production. Therefore, LBN might increase trabecular outflow in addition to promoting uveoscleral outflow.
8.A Case of Non-nasal T/NK-cell Lymphoma Occurring in A Patient with Autiphospholipid Syndrome.
Jae Wang KIM ; Sang Seok KIM ; Kwang Joong KIM ; Jong Min KIM ; Chong Ju LEE ; Hyeong Kik SHIN
Korean Journal of Dermatology 1999;37(2):229-233
Non-nasal T/NK-cell lymphoma(TNKCL) without nasal cavity invasion is a subtype of angiocentric T-cell lymphomas showing the biphenotype of the T-cell and NK-cell. This tumor is characterized by the absence of clonal rearrangement of the T-cell receptor gene, frequent association with Epstein- Barr virus(EBV), poor clinical course, and common extranodal invasion. Antiphospholipid syndrome (APS) is characterized by repetitive spontaneaus abortion, thrombocytopenia, thrombotic symptoms and the positivity to the antiphospholipid antibody. Our patient was a 35-year-old woman with skin lesion on her face. Previously, she had been diagnosed of APS. Histopathological, immunohistochemical and serologic studies could disclose EBV-associated non-nasal TNKCL.
Adult
;
Antibodies, Antiphospholipid
;
Antiphospholipid Syndrome
;
Female
;
Genes, T-Cell Receptor
;
Humans
;
Lymphoma*
;
Lymphoma, T-Cell
;
Nasal Cavity
;
Skin
;
T-Lymphocytes
;
Thrombocytopenia
9.Two Cases of Generalized Pustular Psoriasis Followed by Acquired Bullous Disease.
Jae Wang KIM ; Sang Seok KIM ; Kwang Joong KIM ; Jong Min KIM ; Chong Ju LEE ; Hyeong Sik SHIN
Annals of Dermatology 1999;11(1):41-46
We herein present two cases of generalized pustular psoriasis(GPP) followed by acquired bullous diseases during antipsoriatic management. Although there were several reports de-scribing the coexistence of psoriasis vulgaris and autoimmune bullous diseases such as bullous pemphigoid or pemphigus vulgaris(PV), a coexistence of GPP and bullous disease was sparcely reported. In one patient, we could define atypical autoantigen which was distinct from the other known antigens in documented cases of bullous diseases. The other case was compatible with PV. The psoriatic lesions and bullous eruptions of the two patients cleared in several weeks after administration of cyclosporine.
Cyclosporine
;
Humans
;
Pemphigoid, Bullous
;
Pemphigus
;
Psoriasis*
10.The Characteristics of Associative Learning of Reward Approach and Loss Aversion in Schizophrenia.
Sunyoung PARK ; Seok Hyeong KIM ; Il Ho PARK ; Jung Hwan KIM ; Jae Jin KIM ; Min Seong KOO ; Jungeun SONG
Korean Journal of Schizophrenia Research 2012;15(2):59-65
OBJECTIVES: Schizophrenia patients have deficits of prediction and learning related to dopaminergic dysfunction. It is hypothesized that there would be different characteristics in associative learning of reward approach and loss aversion between controls and patients. METHODS: Participants were 23 healthy participants and 20 out-patients fulfilling criteria for schizophrenia according DSM-IV-TR. Using a monetary incentive contingency reversal task, successful learning rates, numbers of trials and errors till learning, numbers of trials of maintaining learning, response times were measured. Characteristics of learning were compared between controls and patients. RESULTS: Physical anhedonia and PANSS negative symptom scores correlated with the number of trials while loss aversion was maintained. Overall correct response rates were decreased in patient group, particularly during reward approach learning. Patients required more trials and errors to learn reward approach than controls. There were no significant differences in learning performance and reaction times between groups during loss avoidance learning. CONCLUSION: These results support previous reports of deficits in reward-driven learning in schizophrenia. However, anhedonia and negative symptoms were associated with the preserved function of loss avoidance learning.
Anhedonia
;
Avoidance Learning
;
Humans
;
Learning
;
Motivation
;
Outpatients
;
Reaction Time
;
Reinforcement (Psychology)
;
Reward
;
Schizophrenia