1.Combination Therapy with Griseofulvin and Immunotherap (DNCB, DPCP)on Plane Warts.
Sang Won JEONG ; Seung Hoon CHA ; Seok Don PARK
Korean Journal of Dermatology 1999;37(3):320-324
BACKGROUND: Although several kinds of treatment methods(destructive therapy, immunotherapy, etc) for plane warts have been attempted but there have been no entirely satisfactory treatments, because the plane wants are seen to recur frequently. OBJECTIVE: This study was aimed to evaluate the combination therapy of griseofulvin and immunotherapy(dinitrochlorobenzene=DNCB, diphenylcycloprope none=DPCP) on plane warts. METHOD: Sixteen patients(age range, 9 to 41; mean age, 21.8 years) with VPJ were treated with the combination therapy with griseofulvin(500mg/day) and single contact immunotherapy(DNCB or DPCP).
Dinitrochlorobenzene
;
Griseofulvin*
;
Immunotherapy
;
Warts*
2.Diagnostic Value of Immediate CT after Chemoembolization in Patients with Hepatocellular Carcinoma: Comparison with 2-3 Week Delayed CT.
Yong Hoon KIM ; Jong Hoon KIM ; Soon Joo CHA ; Gham HUR ; Myeong Seok JEONG ; Jeong Joo WOO ; Jeong Wook SEO ; Jeong Hyeok KIM
Journal of the Korean Radiological Society 1995;33(2):247-251
PURPOSE: Lipiodol CT is a important modality for the diagnosis of hepatocellular carcinoma and compared is usually performed at 2-3 week after Lipiodol injection. Therefore, we assessed and the diagnostic value and merits of immediate CT after chemoembolization from there of 2-3 week delayed Lipiodol CT. MATERIALS AND METHODS: Thirty three cases of chemoembolization which were performed both immediate CT after chemoembolization and 2-3 week delayed Lipiodol CT were reviewed retrospectively. They were divided into four grades according to pattern of lipiodol uptake by three radiologists. The diagnostic value of immediate Lipiiodol CT was compared to delayed Lipiodol CT. RESULTS: Grade 0 was two cases(3.0%) and Grade 1 was seven cases(21.2%). In the cases of Grade 2(23/33, 69.7%) tumor uptake could be dishng wished from parenchymal uptake of Lipiodol by its density and pattern. Tumor uptake showed dense and homogeneous pattern, but parenchymal uptake revealed less dense and hepatoram-like wedge shaped pattern. Lipiodol uptake of tumor in Grade 3(1/24, 3.0%) was equal to that in delayed Lipiodrl CT. Grade 3 and 2(72.7%) of the immediate Lipiodol CT were not inferior to delayed Lipiodol CT in its diagnostic value. CONCLUSION: The immediate Lipiodol CT could make rapid establishment of treatment plan and are expected to be more convenient than delayed CT for the patients.
Carcinoma, Hepatocellular*
;
Diagnosis
;
Ethiodized Oil
;
Humans
;
Retrospective Studies
3.A Case of Cervical Tab.
Jae Hoon CHUN ; Sang Won JEONG ; Seung Hoon CHA ; Seok Don PARK
Korean Journal of Dermatology 2000;38(2):278-280
Cervical tab is one of rare developmental anomalies of the brachial apparatus which appears as firm, protruding papule or nodule on the neck along the line of anterior border of the sternocleidomastoid muscle. A 5 year-old male patient developed a pea sized, movable, semi-solid mass on the lower portion of right sternocleidomastoid muscle area. On microscopic examination, well-marginated oval shaped cartilage was present. Individual cells in the lacunae had ample cytoplasm and eccentric nucleus. Verhoeff-van Gieson stained section of the mass showed cartilage with a rich elastic network in the matrix, most heavily concentrated about the chondrocyte. We report a rare case of cervical tab manifesting as a skin-colored nodule on the sternocleidomastoid muscle area.
Cartilage
;
Child, Preschool
;
Chondrocytes
;
Cytoplasm
;
Humans
;
Male
;
Neck
;
Peas
4.A Case of Mycosis Fungoides.
Sang Won JEONG ; Jae Hoon CHUN ; Seung Hoon CHA ; Seok Don PARK
Korean Journal of Dermatology 1999;37(9):1364-1366
We describe a case of mycosis fungoides (infiltrative plaque type) in an 86-year-old male. He had experienced dark erythematous round plaques on the face, trunk, buttock, upper and lower extremities. Histopathologic findings revealed band-like superficial dermal infiltration of atypical lymphocytes, epidermotropism, and Pautrier's microabscess in the epidermis. The infiltrative cells were positivly stained with CD3, but not with a CD20. He was treated with a topical application of 0.2% carmustine, but he died due to poor general condition and septicemia.
Aged, 80 and over
;
Buttocks
;
Carmustine
;
Epidermis
;
Humans
;
Lower Extremity
;
Lymphocytes
;
Male
;
Mycosis Fungoides*
;
Sepsis
5.Natural History of Unilateral Ureteropelvic Junciton Obstructed Kidney : Five Cases of High Grade Hydronephrosis.
Ky Hyun CHUNG ; Jeong Seok HWA ; Sang Hoon PAIK ; Jin Soo PAK ; Jin Kyu LIM ; Jae Hoon CHOI
Journal of the Korean Society of Pediatric Nephrology 2000;4(1):57-62
To evaluate the sensitivity and specificity of transthoracic fine needle aspiration cytology(TFNAC) in the preoperative diagnosis of pulmonary nodules, a retrospective analysis was carried out on a consecutive series of 200 TFNACs. They included 186 primary malignant tumors, 66 squamous cell carcinomas, 65 adenocarcinomas, 36 small cell carcinomas, 7 large cell carcinomas, 4 carcinoids, 8 others, 9 metastatic tumors, and 5 benign tumors. On cytohistologic correlation of malignant pulmonary tumors, the pro- cedure had a sensitivity of 97.3% and a specificity of 100%. A 86.6% correct correlation between the cytologic and histologic diagnoses was achieved. Five out of the 7 undifferentiated large cell carcinomas, 10 out of the 65 adenocarcinomas, 2 out of the 36 small cell carcinomas, and 2 out of the 66 squamous cell carcinomas were turned out to be mistyped in cytologic diagnosis. We concluded that TFNAC is a highly sensitive and specific preoperative diagnostic procedure in the investigation of patients with discrete pulmonary nodules in whom the specific cell type of the malignant neoplasm has important implications in treatment modality and prognosis.
Adenocarcinoma
;
Bezafibrate
;
Biopsy, Fine-Needle
;
Carcinoid Tumor
;
Carcinoma, Large Cell
;
Carcinoma, Small Cell
;
Carcinoma, Squamous Cell
;
Diagnosis
;
Endometrial Neoplasms
;
Female
;
Humans
;
Hydronephrosis*
;
Kidney*
;
Natural History*
;
Papanicolaou Test
;
Prognosis
;
Retrospective Studies
;
Sensitivity and Specificity
6.A Case of Nasopharyngeal Teratoma Showing Upper Airway Obstruction.
Jeong Ho JEON ; In Seok LIM ; Chul Hwa KIM ; Byeng Hoon YOO
Journal of the Korean Pediatric Society 1994;37(4):560-564
Neoplasms of the nasophrynx are rare in neonates and infants. The most common nasopharyngeal tumor encountered in this age group is teratoma-neoplasm containing multiple heterotopic tissues. Four histologic types of nasopharyngeal teratoma occur-dermoid, teratoid, true teratoma, epignathiof which dermoid is most frequently seen. We have experienced a case of nasopharyngeal teratoma in a female neonate with signs and symptoms of upper airway obstruction. It was diagnosed by cervical. CT and confirmed as ture teratoma by histological examination. Nesopharyngeal teratoma was removed by contact Nd:YAG laser. In addition, we briefly reviewed the literature of neonatal nasopharyngeal teratoma.
Airway Obstruction*
;
Choristoma
;
Dermoid Cyst
;
Female
;
Humans
;
Infant
;
Infant, Newborn
;
Teratoma*
7.A Case of Linear IgA Bullous Dermatosis.
Sang Won JEONG ; Sang Won LEE ; Seung Hoon CHA ; Seok Don PARK
Korean Journal of Dermatology 1998;36(5):962-964
We describe an 18-year-old male with generalized pruritic, tense annular or polycyalic blistera on normal-appearing skin or erythematous bases. Histopathological fmdings of an iatact early blistering showed subepidermal blistering and papillary neutrophilic gnicroabscesses. A direct immunofluctescent study of a section from the skin adjacent to a lesioti revealed linear deposits of IgA at the dermoepidermal junction. There were no deposits of IgG, lgM, or C3. In 1.0M NaC1 eplit skin, IgA was found to be bound linearly on the epidermal roof. The patient respmded weIl to eteroid and dapsone therapy.
Adolescent
;
Blister
;
Dapsone
;
Humans
;
Immunoglobulin A
;
Immunoglobulin G
;
Linear IgA Bullous Dermatosis*
;
Male
;
Neutrophils
;
Skin
;
Transcutaneous Electric Nerve Stimulation
8.An experimental study for ear reconstruction using the perichondrial flap.
Yong Chan BAE ; Seong Hoon JEONG ; Seok Kwun KIM ; Sung Soo KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1991;18(4):633-639
No abstract available.
Ear*
9.A Case of Relapsing Polychondritis.
Young Gull KIM ; Jeong Hoon JANG ; Jong Seong AHN ; Kwang Hyun CHO ; Seok Joon PARK
Korean Journal of Dermatology 1999;37(5):676-678
Relapsing polychondritis is a rare inflammatory disorder affecting the cartilaginous structures throughout the body. Although there is no pathognomonic laboratory tests, clinical features, when coupled with histopathologic findings, enable one to make a diagnosis of relapsing polychondritis. A 26-year-old man presented with purplish, swollen, and tender auricles and injected eyes. His symptoms had developed eight months ago and fluctuated irrespective of various medications such as corticosteroids and antibiotics. Histopathologic examination revealed loss of basophilic staining of the cartilage with some dissolution of its structures. Treatment was initiated with dapsone, However, the remission was too immediate to be considered as a effect of dapsone.
Adrenal Cortex Hormones
;
Adult
;
Anti-Bacterial Agents
;
Basophils
;
Cartilage
;
Dapsone
;
Diagnosis
;
Humans
;
Polychondritis, Relapsing*
10.A Case of Acute Myeloid Leukemia with an Unusual Phenotype.
Mi Hyang KIM ; Seok Hoon JEONG
Korean Journal of Clinical Pathology 1998;18(1):42-45
We introduce an unusual case of acute myeloid leukemia (AML) showing strong myeloperoxidase (MPO) positivity without any lineage-specific cell surface marker expression, i.e. myelomonocytic antigens CD13, CD14, CD15 and CD33; or B-lymphoid antigens CD10, CD19, CD20, CD22 and surface immunoglobulin; or T-lymphoid antigens CD2, CD3, CD5 and CD7. The case was morphologically AML with maturation (FAB M2) and the cytogenetic study showed t (8; 21) (q22; q22) and missing Y. But Immunophenotypic studies by flow cytometry showed positive reaction ony for CD34 and HLA-DR. We considered this case as a 'presence of t (8; 21) in MPO (+), CD antigen (-) AML'. The myeloid lineage antigens are known to be expressed very early during myeloid differentiation whereas MPO (in its functional form) is viewed as being expressed relatively late in the process. Therefore, this case could be an example of 'asynchronous differentiation' in leukemia.
Cytogenetics
;
Flow Cytometry
;
HLA-DR Antigens
;
Immunoglobulins
;
Leukemia
;
Leukemia, Myeloid, Acute*
;
Peroxidase
;
Phenotype*