1.Bacterial Culture Study of the Hip Joint Fluid during Primary Total Hip Arthroplasty.
Chang Dong HAN ; Joon Seok SOHN ; Wahn Sub CHOE ; Joo Hyung YOO
The Journal of the Korean Orthopaedic Association 1998;33(1):18-23
Infection in primary total hip arthroplasty may cause catastrophic results and is the major reason for implant failure. The purpose of this study was to evaluate the utility of the hip joint fluid culture as a method of predicting the possibility of a hip joint infection by calculating the sensitivity, specificity and accuracy. We performed 628 primary total hip arthroplasty and aerobic and anaerobic bacterial cultures for hip joint fluid between January 1989 and June 1996. The hip joint fluid culture was routinely performed to evaluate the utility of the femoral head for bone banking. Thirty-two cases out of the 628 hips showed positive intraoperative culture and 596 cases showed negative intraoperative culture. The isolated organisms from 32 positive cultures were 11 for Staphylococcus aureus, eight for Staphylococcus coagulase negative, seven for Enterococcus, three for E.coli and one each for Enterobacter, Acinetobacter and Pseudomonas. Anaerobic culture was negative in all cases. In the positive intraoperative culture cases, none had delayed infection during the follow-up period. But in the negative intraoperative culture cases, one case had acute infection and two cases had delayed infection. In the case with acute infection, Staphylococcus aureus was isolated and on two cases with delayed infection, Enterococcus and Staphylococcus coagulase negative were isolated, respectively. All 32 positive culture cases were fa~lse positive and 595 negative culture cases were true negative and one negative culture case was fa~lse negative. The sensitivity of the hip joint culture was 0%, the specificity was 94.9% and the accuracy was 0%. The specificity of hip joint fluid culture in primary total hip arthroplasty was high, hut the sensitivity score was zero. Therefore, the hip joint fluid culture should not be used for a routine check of infection status in primary total hip arthroplasty. We recommend the hip joint fluid culture in revision arthroplasty or hips in which infection is clinically suspected.
Acinetobacter
;
Arthroplasty
;
Arthroplasty, Replacement, Hip*
;
Bone Banks
;
Coagulase
;
Enterobacter
;
Enterococcus
;
Follow-Up Studies
;
Head
;
Hip Joint*
;
Hip*
;
Pseudomonas
;
Sensitivity and Specificity
;
Staphylococcus
;
Staphylococcus aureus
2.Attachment and Behavior Problems in Adolescents: Internalizing and Externalizing Problems.
So Hee LEE ; Kyung Sun NOH ; Seok Han SOHN ; Jung OAK ; Kwang Iel KIM
Journal of Korean Neuropsychiatric Association 2002;41(2):274-282
OBJECTIVE: The purpose of this study was to examine the relationship between attachment and behavior problems in adolescents. METHOD: A sample of 792 high school students were examined. Revised Adult Attachment Scale, Self-report Attachment Style, Youth Self-Report Child Behavior Checklist (YSR) were used to measure the attachment quality, the attachment pattern and the behavior problems respectively. RESULTS: As to the attachment quality, high score in fear of rejection, low dependability and low intimacy were related to the development of adolescent's internalizing problems. As to the attachment pattern, preoccupied and fearful with attachment experience were linked to the internalizing behavior problems of higher level as well as 'Attention problems' and 'Aggressive behavior' sub-scales of externalizing ones on YSR. CONCLUSION: High fear of rejection, low dependability and low intimacy characterise the insecure attachment. So the insecure attachment might predict the development of all internalizing behavior problems, attention problems and aggressive behavior in adolescents. Also the result suggested that the adolescents classified as Dismissing attachment may have a positive view of the self and may minimize the self reported behavior problems.
Adolescent*
;
Adult
;
Checklist
;
Child
;
Child Behavior
;
Humans
;
Self Report
3.Association between Olfactory Deficit and Motor and Cognitive Function in Parkinson’s Disease
Han Soo YOO ; Seok Jong CHUNG ; Yang Hyun LEE ; Byoung Seok YE ; Young H. SOHN ; Phil Hyu LEE
Journal of Movement Disorders 2020;13(2):133-141
Objective:
To investigate whether baseline olfactory dysfunction in Parkinson’s disease (PD) patients is associated with baseline and longitudinal motor and cognitive function.
Methods:
We recruited 228 drug-naïve PD patients who were followed for a mean of 6 years. Patients underwent the Cross-Cultural Smell Identification Test (CCSIT), a neuropsychological test, and N-(3-[18F]fluoropropyl)-2β-carbomethoxy-3β-(4-iodophenyl) nortropane positron emission tomography within 6 months of the baseline evaluation. Olfactory dysfunction was categorized as normosmia (CCSIT score ≥ 9), hyposmia (CCSIT score 5–8), and anosmia (CCSIT score ≤ 4). During the follow-up period, we investigated changes in the levodopa-equivalent dose (LED) and the occurrence of wearing-off, levodopa-induced dyskinesia, and dementia.
Results:
Among the PD patients, 80.7% were hyposmic at the time of diagnosis, and 26.1% were anosmic. Baseline olfactory dysfunction was not associated with either initial parkinsonian motor symptoms or with the longitudinal LED increment and motor complications. Meanwhile, the anosmic group had lower baseline scores on the Korea version of the Boston Naming Test and Stroop color reading test than the normosmic and hyposmic groups. The anosmic group exhibited a higher rate of conversion to dementia than the normosmic [adjusted hazard ratio (HR) 3.99, 95% confidence interval (CI) 1.08–14.72] and hyposmic (adjusted HR 2.48, 95% CI 1.15–5.32) PD groups, regardless of baseline motor deficits and cognitive status.
Conclusion
Baseline olfactory dysfunction was not associated with motor deficits and complications, but it was associated with cognitive dysfunction and prognosis, suggesting that severe olfactory impairment may reflect early cortical involvement, probably in the frontotemporal region, and rapid spreading of Lewy body pathology.
4.A Study of Adolescent Problem Behaviors and Parenting Behaviors.
Seok Han SOHN ; Kyung Sun NOH ; Myo Yeon HUH ; Hyun Oak JUNG ; Soh Hee LEE ; Sejoo KIM
Journal of Korean Neuropsychiatric Association 2001;40(4):605-615
OBJECTIVES: The purpose of this study is to evaluate the problem behaviors of adolescents and to discriminate between parenting behaviors of problem behavior groups and those of non-problem behavior group. METHODS: The subjects of this study were 792 high school students in Seoul. We administered 'Parenting Behavior Inventory' and Korean version of Youth Self-Report(K-YSR) to the subjects in order to evaluate the parenting behaviors perceived by adolescents and the problem behaviors of adolescents. We analyzed the relationship between parenting behaviors and problem behaviors. We classified the subjects into problem behavior groups(internalizing group, externalizing group, internalizing-externalizing group) and a non-problem behavior(normal) group. We studied the differences of parenting behaviors among the groups. RESULTS: The results are as follows. 1) There were significant negative correlations between the positive parenting behaviors such as affection, reasoning, and monitoring and the problem behaviors of adolescents. By contrast, there were significant positive correlations between the negative parenting behaviors such as physical abuse, intrusiveness, over-expectation, neglect, and inconsistency and the problem behaviors of adolescents. 2) Adolescents of the internalizing group perceived significantly more parental abuse, intrusiveness, over-expectation, neglect, and inconsistency than those of normal group. Meanwhile, they perceived significantly less affection than normal adolescents. Adolescents of the externalizing group also perceived significantly more parental abuse, intrusiveness, over-expectation, neglect, and inconsistency than those of normal group. Also, they perceived significantly less monitoring than normal adolescents. 3) Adolescents of the internalizing-externalizing group perceived significantly more intrusiveness from both parents than those of either the internalizing or the externalizing groups. Adolescents of the internalizing-externalizing group perceived significantly less affection and more neglect from their mothers than those of the internalizing or the externalizing groups. In addition, adolescents of the internalizing-externalizing group perceived significantly more physical abuse from their fathers than those of the internalizing or the externalizing groups. CONCLUSION: Parenting behaviors such as abuse, intrusiveness, over-expectation, neglect, and inconsistency are associated with both internalizing and externalizing problems. In contrast, our results suggest that parenting behaviors such as affection, monitoring, and reasoning might decrease the various problem behaviors of adolescents.
Adolescent*
;
Fathers
;
Humans
;
Mothers
;
Parenting*
;
Parents*
;
Seoul
5.A Case of Primary Signet Ring Cell Carcinoma of the Lung.
Won Il CHOI ; Jeong Ho SOHN ; Oh Young KWON ; Jeong Suk HUR ; Jae Seok HWANG ; Seong Beom HAN ; Hong Suck SONG ; Young June JEON ; Kun Young KWON
Tuberculosis and Respiratory Diseases 1994;41(5):562-567
Signet ring cell carcinoma has been previously described in many organs, most frequently in the stomach, and rarely in the colon, rectum, gallbladder, pancreas, breast, nadsal cavity, prostate, urinary bladder and ureter. Signet ring cell carcinomas in the lung, especially, when examined by small biopsies, are generally believed to be metastatic. This case was diagnosed by bronchoscopic biopsy. We also examined various organs by noninvasive method, including UGI series, barium enema and abdomen CT scarf, but all studies were nomal. Patient received cisplatin and etoposide combination chemotherapy followed by local radiotherapy ai a primary non-small cell lung cancer. Patient died of his disease 6 months after diagnosis. Now we report a case of primary signet ring cell carcinoma of the lung.
Abdomen
;
Barium
;
Biopsy
;
Breast
;
Carcinoma, Non-Small-Cell Lung
;
Carcinoma, Signet Ring Cell*
;
Cisplatin
;
Colon
;
Diagnosis
;
Drug Therapy, Combination
;
Enema
;
Etoposide
;
Gallbladder
;
Humans
;
Lung Neoplasms
;
Lung*
;
Pancreas
;
Prostate
;
Radiotherapy
;
Rectum
;
Stomach
;
Ureter
;
Urinary Bladder
6.Clincal Manifestations of Patients Dying of Severe Community Acquired Pneumonia.
Won Il CHOI ; Jeong Ho SOHN ; Oh Yong KWUN ; Jeong Sook HEO ; Joe Seok WHANG ; Seong Beom HAN ; Young June JEON
Tuberculosis and Respiratory Diseases 1994;41(5):537-545
BACKGROUND: In 1987, the British Thoracic Society (BTS) subjected an extensive list of patient variables to statistical analysis in a prospective study of prognosis in 453 adults with communityacquired pneumonia and, subsequently published guidelines for management of severe community acquired pneumonia. It was hoped that those at risk of dying from community acquired pneumonia could be easily identified and treated appropriately, thereby reducing mortality. To date, severe community acquired pneumonia has not been well studied in Korea. Therefore, we studied retrospectively 10 patients dying of severe community acquired pneumonia in Dongsan Hospital to see clinical manifestations of .dying of severe community-acquired pneumonia. METHODS: Between July 1987 and july 1993, 498 patients were admitted to Keimyung University Dongsan Hospital with community acquired pneumonia, and 77 of them received intensive care. Of the 77 patients, 10 patients died. We reviewed medical records of these patients. RESULTS: 1) The mean age of the patients was 56.2 years(range, 25 to 75 years). There were 7 men and 3 women. Seven patients(70%) were older than 60years of age. 2) The clinical features on admission were as follows: tachypnea, hypoxemia, mental change, cyanosis, leukopenia, leukocytosis, azotemia, hypotension, hypoalbuminemia in order of frequency. Three patients had one abnormal physical finding, 3 patients had 2, 2 patients had 3, and 2 patients had none of these abnormal physical findings. All patients had at least one of the abnormal laboratory findings. 3) A potential bacterial pathogen was isolated in sputum culture from 2 patients. One was E.coli, the other Enterobacter species. Sputum stain were positive in eight cases (G(+)cocci in six, G(+)cocci and G(-)bacilli in two). 4) Features of respiratory failure were the main reasons for ICU transfer, but two patients were transferred only following a cardiac or respiratory arrest in the general ward. 5) The mean of 2.7 different antibiotics were given to the patients. The aminoglycoside and first generation cephalosporin were the most frequently prescribed antibiotics, followed by the third generation cephalosporin and vancomycin. The most frequently prescribed antibiotics combination was a 1st generation cephalosporin plus an aminoglycoside. 6) Save patients death(70%) occured after admission within the first five days, and a mean duration of hospitalization was 11.2 days. CONCLUSION: As the results show most death occured within the first days after admission and aged patients; consequently, an aggressive intensive treatment should be provided early to the patients with severe community acquired pneumonia, and we should pay more attention to the aged patients.
Adult
;
Anoxia
;
Anti-Bacterial Agents
;
Azotemia
;
Cyanosis
;
Enterobacter
;
Female
;
Hope
;
Hospitalization
;
Humans
;
Hypoalbuminemia
;
Hypotension
;
Critical Care
;
Korea
;
Leukocytosis
;
Leukopenia
;
Male
;
Medical Records
;
Mortality
;
Patients' Rooms
;
Pneumonia*
;
Prognosis
;
Prospective Studies
;
Respiratory Insufficiency
;
Retrospective Studies
;
Sputum
;
Tachypnea
;
Vancomycin
7.An Artifact Caused by Using the Inadequate Acquisition Parameter in Tc-99m ECD Brain Perfusion SPECT.
Han Kyung SEO ; Min Woo KIM ; Seok Tae LIM ; Myung Hee SOHN
Korean Journal of Nuclear Medicine 2004;38(6):540-542
Although artifacts in tomographic imaging can arise from a number of sources, this case presents an artifact caused by using inadequate acquisition parameters which do not match the collimator with which a camera equipped in Tc-99m ECD brain SPECT. Whenever the collimator in tomographic studies is changed, we should take care to use suitable parameters of acquisition protocol according to the collimator with which a camera is fitted. Other ways to prevent an error of this type is to use a point source.
Artifacts*
;
Brain*
;
Perfusion*
;
Tomography, Emission-Computed, Single-Photon*
8.The Evaluation of Factors Which Influence Binding Efficiency of Modified in Vivo Erythrocyte Labeling Technique.
Han Kyung SEO ; Min Woo KIM ; Seok Tae LIM ; Myung Hee SOHN
Korean Journal of Nuclear Medicine 2004;38(4):300-305
PURPOSE: We underwent this study to evaluate the factors which influence labeling efifciency when modified in vivo erythrocyte labeling technique was used. MATERIALS AND METHODS: Thirty healthy volunteers (M: F=19: 11, age: 25 +/- 2 yrs) were enrolled in this study. Totally, two hundred ten samples were obtained from them. The 1 mg of stannous pyrophosphate was injected intravenously at the beginning of labeling. After suitable tinning time (5 min, 20 min, 35 min) passed by, blood (5 mL, 3 mL or 1 mL) was withdrawn into 10 mL syringe previously containing Tc-99m (740 MBq) and anticoagulant (heparin, ACD or CPDA) through 19-gauged scalp needle. The generator ingrowth time of Tc-99m was within 24 hrs in each case. The blood samples were placed on rotating invertor during incubation (10 min, 25 min, 40 min) but some of them were not. Immediately after the conclusion of incubation, the labeled blood specimens to analyze were centrifuged. and then %Unbound Tc-99m was calculated. Statical analysis was used paired T-test and one way ANOVA with SPSS 10.0. RESULTS: The binding efficiency at 1 mL of blood volume was 73 +/- 32%, 91 +/- 10% at 3 mL and 96 +/- 7% at 5 mL (p< 0.01). The binding efficiency at 5 min of tinning time was 45 +/- 23%, 98 +/- 6% at 20 min and 97 +/- 8% at 35 min (p< 0.001). The binding efficiency at 10 min of incubation time was 96 +/- 7%, 95 +/- 12% at 25 min and 98 +/- 3% at 40 min (p> 0.05). The binding efficiency in case of using rotating invertor was 96 +/- 7% and the binding efficiency in case of not using it was 87 +/- 18% (p> 0.05). There was no significant difference between them. In binding efficiency according to kinds of anticoagulants, ACD was 98 +/- 4%, CPDA was 97 +/- 6% and heparin was 89 +/- 20% (p< 0.001). CONCLUSION: When modified in vivo erythrocyte labeling technique is used with Tc-99m, the methods to obtain the highest labeling efficiency are as follow. The withdrawing blood volume should be over 3 mL, tinning time should be kept between 20 min and 35 min, and incubation time should be kept between 10 min and 40 min. ACD or CPDA have to be used as a anticoagulant except heparin and the blood samples should be placed on rotating invertor during incubation.
Anticoagulants
;
Blood Volume
;
Erythrocytes*
;
Healthy Volunteers
;
Heparin
;
Needles
;
Scalp
;
Syringes
;
Tin
9.Colon Perforation by an Ingested Toothpick.
Jin Kyung CHO ; Jun Seok PARK ; Dae Kon SOHN ; Han Shick LEE
Journal of the Korean Society of Emergency Medicine 2002;13(3):366-368
Foreign bodies in the gastrointestinal (GI) tract can be seen in all age groups and is not uncommon to see in the emergency department. Most are pediatric, edentulous, incarcerated and/or psychiatric patients. Since ingested objects are expected to pass spontaneously in 80% to 90% of patients with normal anatomy, direct foreign body removal using surgical intervention is rarely required. However, an ingested toothpick is of surgical interest as a cause of significant morbidity and even mortality. This is due to the difficulty in preoperative diagnosis resulting from a lack of history of ingestion of the toothpick and to the toothpick's radiolucent qualities. We report the case of a patient with peritonitis due to perforation of the sigmoid colon, a complication of accidental ingestion of a toothpick, that was diagnosed at the surgical field. Related literature is reviewed together.
Colon*
;
Colon, Sigmoid
;
Diagnosis
;
Eating
;
Emergency Service, Hospital
;
Foreign Bodies
;
Humans
;
Mortality
;
Peritonitis
10.The Usefulness of Fetal MRI for Prenatal Diagnosis.
Yong Seok SOHN ; Myung Joon KIM ; Ja Young KWON ; Young Han KIM ; Yong Won PARK
Yonsei Medical Journal 2007;48(4):671-677
PURPOSE: Fast MRI has provided detailed and reproducible fetal anatomy. This study was performed to evaluate the usefulness of fetal MRI for prenatal diagnosis. MATERIALS AND METHODS: Fifty-six fetuses with congenital abnormalities on ultrasonography were evaluated by fetal MRI from 2001 to 2004 in Severance Hospital. Final diagnosis was made by postnatal pathology, postnatal MRI, and other modalities (such as ultrasound, retrograde pyelogram). A 1.5-Tesla superconductive MR imaging unit was used to obtain half-Fourier acquisition single-shot turbo spin images. RESULTS: Of the 56 fetuses, intracranial abnormalities were found in 26 fetuses, intraabdominal abnormalities in 17 fetuses, intrathoracic in 6 fetuses, head and neck in 5 fetuses, and other sites in 2 fetuses. There were six cases in which the diagnoses of fetal MRI and ultrasonography differed. In such cases, fetal MRI provided more exact diagnosis than ultrasonography (5 vs. 0). Three fetuses with intracranial abnormalities on ultrasonography were diagnosed as normal by fetal MRI and in postnatal diagnosis. CONCLUSION: Although ultrasonography is known as a screening modality of choice in the evaluation of fetus because of the cost-effectiveness and safety, the sonographic findings are occasionally inconclusive or insufficient for choosing the proper management. Thus, in this study, we suggest that fetal MRI is more useful than ultrasonography for the evaluation of intracranial abnormalities in some instances. For prenatal counseling and postnatal treatment planning, fetal MRI can be informative when prenatal ultrasonography is inadequate and doubtful.
Female
;
Fetal Diseases/*diagnosis/ultrasonography
;
Humans
;
*Magnetic Resonance Imaging
;
Pregnancy
;
Prenatal Diagnosis/*methods
;
Retrospective Studies
;
Sensitivity and Specificity
;
Ultrasonography, Prenatal