Multiple myeloma is a malignant proliferation of the atypical plasma cells which usually involves antibody synthesis in the immune system. Systemic manifestations include anemia, renal failure, osteoporosis, immune deficiency symptom. Ophthalmolgically this disease involves cornea, conjunctiva, uvea, iris, ciliary body, retinal vessels, extraocular muscles and optic nerve. The authors experienced a case of multiple myeloma with hyperviscosity syndrome who presented with central retinal vein occlusion in both eye.
Anemia ; Ciliary Body ; Conjunctiva ; Cornea ; Immune System ; Iris ; Multiple Myeloma* ; Muscles ; Optic Nerve ; Osteoporosis ; Plasma Cells ; Renal Insufficiency ; Retinal Vein* ; Retinal Vessels ; Uvea

We compared postoperative visual outcome and corneal refractive power depending on preoperative corneal topographic pattern and the predictibility of corneal topographic measurement compared with keratometric measurement after PRK. The subjects were 91 eyes divided into two goups composed of 44 eyes, symmetric bow tie type(SB) and 47 eyes, asymmetric bow tie type (aSB). The visual acuity, central power, and topographic pattern were measured before operation, postoperative 1 week, 1, 2 and 6 month in two groups, but no statistical difference(p>0.05). The averages of uncorrected visual acuity at 6 month were improved to 0.80(SB) and 0.85(aSB) from 0.09(SB) and 0.11(aSB) before operation. Topographic central refractive powers of +42.98D (SB), +43.32D(aSB) before operation were changed to +37.68D(SB), 37.56D(aSB) at 6month. The pattern of the region affected by the excimer laser was classified by key hole type 38%(SB) , 34%(aSB) , uniform roud type 41%(SB), 43%(aSB), semicircular type 21%(SB), 23%(aSB). The proportion of the difference less than one diopter between PRK setting and the change of the corneal refractive power at 6month was 36% and 76% in keratometric and topographic measurement. Above results show that the asymmetricity of bow tie type did not influence the visual outcome. The topographic measurement was better than keratometric measurement in evaluating the corneal refractory change after PRK.
Lasers, Excimer* ; Visual Acuity