BACKGROUND: Low birth weight and high birth weight are closely related to perinatal complications. The purpose of this study is to estimate the association of prepregnancy weight, maternal weight gain and infant birth weight. METHODS: The effect on birth weight in 724 live births after 38~42 weeks gestation was studied at Taegu Medical Center, between January, 1997, and August, 1998. Pregnant women with hypertension, diabetes mellitus, multiple pregnancy and drug abuse were excluded because of their possible influence on birth weight. To study the effect on infant birth weight, multiple regression analysis was carried out. RESULTS: We evaluated 724 pregnant women and their babies. Mean prepregnancy weight was 52.2+/-.9kg, mean maternal weight gain was 13.0+/-.6kg, and mean BMI(Body Mass Index) was 20.5+/-2.5kg/m(2). Mean gestational age was 278+/-7.3days and mean birth weight was 3,320.5+/-405.2gm. Correlation coefficient between birth weight and prepregnancy weight was 0.347(p<0.01), and maternal weight gain was 0.248(p<0.01), and BMI(Body Mass Index) was 0.261(p<0.01). Birth weight was significantly correlated with prepregnancy weight(p<0.01) and maternal weight gain(p<0.01), but prepregnancy weight was not significantly correlated with maternal weight gain(p<0.05). Prepregnancy weight had most apparent influence on birth weight. CONCLUSIONS: Prepregnancy weight and maternal weight gain was positively related to birth weight. These results suggest that there are good effects of properly controlling prepregnancy weight and maternal weight gain in pregnant women and their babies.
Birth Weight* ; Daegu ; Diabetes Mellitus ; Female ; Gestational Age ; Humans ; Hypertension ; Infant ; Infant, Low Birth Weight ; Infant, Newborn ; Live Birth ; Parturition* ; Pregnancy ; Pregnancy, Multiple ; Pregnant Women ; Substance-Related Disorders ; Weight Gain*

BACKGROUND: The normal sinus heart rate standard of 60 to 100 beats per minute was set by the NYHA(New York Heart Association) in 1928. It has long been accepted to physicians, but clinical studies and experience suggest that both these limits are too high. Thus we reexamined to define operationally normal sinus heart rate that are scientifically and clinically acceptable. METHODS: Total 1,930 subjects(aged 20 to 92 years) were analyzed and evaluated for age, sex, body mass index(BMI), systolic blood pressure, diastolic blood pressure, and resting heart rates by electrocardiogram. We used Pearson's correlation test and t-test to analyze these data. RESULTS: Among 1930 subjects, 982 cases were male(51%) and 948 cases were female (49%), whose mean age was 48 years in male and 51 years in female. For the entire sample, mean heart rate and standard deviation was 68 +/- 11 beats/min. There was statistically significant difference between male(67+/-11 beats/min) and female(68+/-10 beats/min)(P<0,05). The prevalence of sinus tachycardia and bradycardia, calculated by current normal standard of 60 to 100 beats/min, was 22.0% (424 cases) and 0.9% (18 cases). Mean +/- two standard deviation yields rounded extremes of 46 to 89 beats/min for normal sinus heart rate. A positive correlations between resting heart rate and age(r=0.11), systolic blood pressure(r =0.17), diastolic blood pressure(r=0.12) were found(P<0.01). CONCLUSIONS: Two extremes of the normal sinus heart rate standard of 60 to 100 beats/min are set too high. They result in lower sensitivity for tachycardia and lower specificity for bradycardia. We propose that normal range for sinus heart rate should be 50 to 90 beats/min which is statistically justified, more realistic for clinical investigation.
Blood Pressure ; Bradycardia ; Electrocardiography ; Female ; Heart Rate* ; Heart* ; Humans ; Male ; Prevalence ; Reference Values ; Sensitivity and Specificity ; Tachycardia ; Tachycardia, Sinus

BACKGROUND: Diseases related with cardiovascular risk factors such as hypertension, diabetes mellitus, coronary artery disease, hyperlipidemia and cerebrovascular disease are increasing according to the change of dietary patterns with economy growth and other causes such as low physical activity. Many studies showed the effects and benefits of exercise in people who had diseases related to cardiovascular risk factors, but there are few studies on the effects of exercise in healthy people. Therefore this study investigated the influence of exercise on cardiovascular risk factors in healthy adults. METHODS: 2,413 people who participated in periodic health examinations at Taegu medical center from May to July, in 1998 were assessed with respect to height, weight, blood pressure, fasting blood glucose, serum total cholesterol and subjects responded to the self-administered questionnaires. We reviewed 881 subjects. Subjects were classified as exereise group if they reported exercising for at least 30 minutes, 5 or more days of the week, and as control group if they reported exercising once a week or less. We observed the difference in Body Mass Index(BMI), fasting blood glucose, systolic and diastolic blood pressure, serum total cholesterol and the prevalence of overweight, hypertension, hypercholesterolemia, hyperglycemia between study groups. RESULTS: There were no differences in sex, age, education, economic status, occupation between the study groups. Serum total cholesterol, systolic and diastolic blood pressure, fasting blood glucose and BMI were significantly lower for the exercise group. The prevalence of overweight, hypertension, and hyperlipidemia were significantly lower for the exercise group. The prevalence of diabetes mellitus were lower for the exercise group, but were not statistically significant. CONCLUSIONS: In healthy peoples, they who were regularly exercise were significantly lowered in cardiovascular risk factors and diseases related with cardiovascular risk factors than nonexercising peopl
Adult* ; Blood Glucose ; Blood Pressure ; Cholesterol ; Coronary Artery Disease ; Daegu ; Diabetes Mellitus ; Education ; Fasting ; Humans ; Hypercholesterolemia ; Hyperglycemia ; Hyperlipidemias ; Hypertension ; Motor Activity ; Occupations ; Overweight ; Prevalence ; Risk Factors* ; Surveys and Questionnaires

BACKGROUND: Diseases related with cardiovascular risk factors such as hypertension, diabetes mellitus, coronary artery disease, hyperlipidemia and cerebrovascular disease are increasing according to the change of dietary patterns with economy growth and other causes such as low physical activity. Many studies showed the effects and benefits of exercise in people who had diseases related to cardiovascular risk factors, but there are few studies on the effects of exercise in healthy people. Therefore this study investigated the influence of exercise on cardiovascular risk factors in healthy adults. METHODS: 2,413 people who participated in periodic health examinations at Taegu medical center from May to July, in 1998 were assessed with respect to height, weight, blood pressure, fasting blood glucose, serum total cholesterol and subjects responded to the self-administered questionnaires. We reviewed 881 subjects. Subjects were classified as exereise group if they reported exercising for at least 30 minutes, 5 or more days of the week, and as control group if they reported exercising once a week or less. We observed the difference in Body Mass Index(BMI), fasting blood glucose, systolic and diastolic blood pressure, serum total cholesterol and the prevalence of overweight, hypertension, hypercholesterolemia, hyperglycemia between study groups. RESULTS: There were no differences in sex, age, education, economic status, occupation between the study groups. Serum total cholesterol, systolic and diastolic blood pressure, fasting blood glucose and BMI were significantly lower for the exercise group. The prevalence of overweight, hypertension, and hyperlipidemia were significantly lower for the exercise group. The prevalence of diabetes mellitus were lower for the exercise group, but were not statistically significant. CONCLUSIONS: In healthy peoples, they who were regularly exercise were significantly lowered in cardiovascular risk factors and diseases related with cardiovascular risk factors than nonexercising peopl
Adult* ; Blood Glucose ; Blood Pressure ; Cholesterol ; Coronary Artery Disease ; Daegu ; Diabetes Mellitus ; Education ; Fasting ; Humans ; Hypercholesterolemia ; Hyperglycemia ; Hyperlipidemias ; Hypertension ; Motor Activity ; Occupations ; Overweight ; Prevalence ; Risk Factors* ; Surveys and Questionnaires

BACKGROUND: Obesity has been accepted as the rusk factor of major chronic diseases in our society. And nutritional assessment is the important issue in respect to obesity evaluation. A self-administrated semiquantitative food frequency questionnaire of which validity is recognized is used in nutritional assessment. But the relationship between nutritional assessment resulted from the questionnaire and the obesity index has not been built until now, so we studied about this relationship. METHODS: Among 324 adults who had visited health screening center from June'95 to August '96, 270 adults were evaluated except who had any chronic disease such as diabetes mellitus, pulmonary tuberculosis, thyroid disease by screening data or low calorie diet for aimed weight loss or inadequate Questionnaire. Nutritional intake was assessed by the self-administrated semiquantitative food frequency questionnaire. We evaluated the activity grade, obesity indices such as body mass index(BMI), waist to hip ratio(WHR), percent body fat using bioelectrical impedance fatness analyzer and serum total cholesterol, HDL-cholesterol, triglyceride. Then we examined the correlation between obesity Indices and nutritional variables each other. We analyzed these results using Pearson's correlation coefficient. RESULTS: We evaluated for a group of 164 men and 106 women whose mean age was 43.9 years, mean BMI was 23.2kg/m2, mean WHR was 0.85 and mean percent body fat was 21.2%. Correlation coefficient between calorie intake to recommended calorie ratio(ICRCR) and BMI was 0.13(P<0.05), WHR was 0.11(P> OR =0.05), and percent body fat was 0.07(P> OR =0.05). Fats intake to recommended fats ratio(IFRFR) and obesity indices didn't show the significant correlation between them. We could not find the significant correlation between cholesterol intake and serum total cholesterol, triglyceride but the significant negative correlation between cholesterol intake and serum HDL-cholesterol(r=-0.14) was found. CONCLUSIONS: Only BMI among obesity indices and ICRCR showed low(r=0.13) correlation coefficient although it is significant. Our results shows that obesity is the complex syndrome influenced by genetic, social, psychological, medical variables besides nutritional impacts.
Adipose Tissue ; Adult ; Caloric Restriction ; Cholesterol ; Chronic Disease ; Diabetes Mellitus ; Electric Impedance ; Fats ; Female ; Hip ; Humans ; Male ; Mass Screening ; Nutrition Assessment* ; Obesity* ; Thyroid Diseases ; Triglycerides ; Tuberculosis, Pulmonary ; Weight Loss ; Surveys and Questionnaires

Xanthogranulomatous pyelonephritis (XGP) is a rare, severe, chronic infection of the kidney resulting in the normal renal parenchyma being replaced by characteristic lipid-laden macrophages (foam cells). It may occur at any age but is extremely rare in children. Correct pre-operative diagnosis is essential for appropriate surgical approach. We report a case of diffuse XGP in a 6-year-old boy which was pre-operatively diagnosed as XGP.
Child* ; Diagnosis ; Humans ; Kidney ; Macrophages ; Male ; Pyelonephritis, Xanthogranulomatous*

Arteriovenous malformation (AVM) of the scrotum is a rare vascular lesion, which is distinguished histologically by ambiguous vessels displaying both arterial and venous characteristics and abnormal muscularization of variable sized ectatic vessels. Complete excision is recommended as a definitive treatment. Here, a case of arteriovenous malformation involving the scrotal vessels is reported.
Arteriovenous Malformations* ; Scrotum

BACKGROUND: A reliable, well-validated home blood pressure(BP) self measurement device could have an important role in the management of hypertension. Rigorous assessment of such a device have not performed well, particularly in the hypertensive range. METHODS: We assessed the National EW274W device(oscillometric) for home messurem of BP according to the standards set out by the British Hypertension Society protocol and American Association for the Advancement of Medical Instrumentation(AAMI). The device was compared with sequential measurements using a standard mercury sphygmomanometer in the same arm in 105 patients aged 16-79 years. The BP of subjects was measured three times at least a week apart. These data were analysed using Pearson's correlation and paired t-test. RESULTS: The device was highly correlated to mercury sphygmomanometer in mean systolic BP(SBP) and mean diastolic BP(DBP) (r=0.93, r=0.93, P<0.05). The device was satisfactory over the whole BP range(SBP 106-182mmHg, DBP 56-116mmHg), with a B grade for SBP and a A grade for DBP(British Hypertension Society protocol) and a PASS for both SBP and DBP(AAMI). Sensitivity and specificity are 84.2%, 93.0%(mean SBP) and 100%, 96.9% (mean DBP). CONCLUSIONS: We concluded the wrist blood pressure meter(National EW274W) for home BP measurement is highly satisfactory and is suitable for clinical use.
Arm ; Blood Pressure* ; Humans ; Hypertension ; Sensitivity and Specificity ; Sphygmomanometers ; Wrist*

BACKGROUND: Overt hypothyroidism is a well-known cause of secondary hyperlipidemia and atherosclerosis. However, there have been some dissenting report of abnormalities and in serum lipid concentration in patients with subclinical hypothyroidism. We have attempted to analyze serum lipid concentrations to investigate whether they are increased in patients with subclinical hypothyroidism and to see if there is a correlation between serum LDL-C and TSH concentrations. METHODS: Serum lipid profiles(total cholesterol, triglycerides, LDL-C, HDL-C) of patients with subclinical hypothyroidism (M/F=7/119) compared with age, sex and body mass index matched control subjects(M/F=14/239) from Jan. 1 . 1996. to Dec. 30. 1997. RESULTS: There were no significant differences of serum total cholesterol, LDL cholesterol, TG, and HDL concentrations in 126 patients with subclinical hypothyroidism and 253 control subjects(178.47+/-35.76mg/dL vs. 173.05+/-35.93mg/dL ; 113.33+/-52.89mg/dL vs 117.64+/-68.70mg/dL ; 112.89+/-33.26mg.dL vs 109.65+/-29.02mg/dL ; 48.60+/-11.34mg/dL vs 46.51+/-11.73mg/dL). There was no correlation between LDL cholesterol and TSH concentrations in subclinical hypothyroidism(r=0.29, p<0.05). CONCLUSION: Serum lipid concentration (total cholesterol, LDL cholesterol, and TG, HDL) was not increased in patients with subclinical hypothyroidism. There was no correltion between serum LDL and TSH levels in patients with subclinical hypothyroidism.
Atherosclerosis ; Body Mass Index ; Cholesterol ; Cholesterol, LDL ; Dissent and Disputes ; Humans ; Hyperlipidemias ; Hypothyroidism* ; Lipoproteins* ; Triglycerides

PURPOSE: Prostate biopsy is used to confirm the prostate cancer. Although first biopsy result was benign, repeat biopsy is recommended for the patient who has higher risk of prostate cancer. In this study, we investigated the PSA change ratio (post-biopsy PSA to baseline PSA) whether it could be predictive factor of prostate cancer and helpful when decided to perform repeat biopsy. MATERIALS AND METHODS: 151 patients, first diagnosed as benign, but underwent repeat biopsy due to clinical suspicion of prostate cancer were included. Post-biopsy PSA was checked 60 minutes later after biopsy. PSA change ratio was defined as post-biopsy PSA to baseline PSA. According to results of repeat biopsy, patients were divided into benign group (group A) and cancer groups (group B). Between two group baseline PSA, PSA density, post-biopsy PSA and PSA change ratio were compared, and most effective cut-off value was analyzed using receiver operating characteristic (ROC). RESULTS: 129 men were benign, 22 men were prostate cancer according to results of repeat biopsy. Between two groups, post-biopsy PSA and PSA change ratio were statically significant differences. (p<0.001, <0.001) The effective cut-off value was 3.0, 3.5 and 4.0 according to ROC. At ROC curve, PSA change ratio was statistically significant for diagnosis of prostate cancer. (AUC 0.800, p<0.001). CONCLUSIONS: PSA change ratio is thought be a predictive factor for prostate cancer. If the PSA change ratio was less than 3.0-4.0, repeat biopsy should be considered to confirm the diagnosis.
Biopsy ; Humans ; Male ; Prostate ; Prostate-Specific Antigen ; Prostatic Hyperplasia ; Prostatic Neoplasms ; ROC Curve