We report three cases of rat mite dermatitis caused by Ornithonysus bacoti(Hirst, 1913), commonly referred to it as the tropicalrat mite. The first case, a 26-year old female had multiple pinhead sized vesicles with peripheral erythematous macule on the upper arms. The second case, a 34-year-old femal had multiple variable sized vesicles with erythematous base on the extremeties. The third case, a 43-year old male had multiple erythematous macules and papules with central punctum on the trunl: and extremities. Histopathologic sections from lesions of the first and second patient showed moderate perivascular lymphahistiocytic infiltration intermingled with some eosinophils. Causative mites, Ornithonyssus bacoti, female were collected around the skin lesion in rase 1, from the house dust in case 2 and furniture in case 3.
Adult ; Animals ; Arm ; Dermatitis* ; Dust ; Eosinophils ; Extremities ; Female ; Humans ; Interior Design and Furnishings ; Male ; Mites* ; Rats* ; Skin

Japan has the highest proportion of older adults worldwide and has consistently strengthened its healthcare system to mitigate the medical and welfare burden associated with population aging. Primary care has been positioned as a key strategy for establishing a sustainable healthcare system within a super-aged society. Japan has pursued this goal through the implementation of community-based integrated care systems, the operation of a long-term care insurance system, the specialized training of primary care physicians, and the establishment of the “Comprehensive Medical Specialist” program. These initiatives aim to optimize the utilization of healthcare resources and ensure the long-term sustainability of the healthcare system. Japan’s experience offers critical insights for Korea, which requires effective strategies to strengthen its primary care system.

Japan has the highest proportion of older adults worldwide and has consistently strengthened its healthcare system to mitigate the medical and welfare burden associated with population aging. Primary care has been positioned as a key strategy for establishing a sustainable healthcare system within a super-aged society. Japan has pursued this goal through the implementation of community-based integrated care systems, the operation of a long-term care insurance system, the specialized training of primary care physicians, and the establishment of the “Comprehensive Medical Specialist” program. These initiatives aim to optimize the utilization of healthcare resources and ensure the long-term sustainability of the healthcare system. Japan’s experience offers critical insights for Korea, which requires effective strategies to strengthen its primary care system.

Japan has the highest proportion of older adults worldwide and has consistently strengthened its healthcare system to mitigate the medical and welfare burden associated with population aging. Primary care has been positioned as a key strategy for establishing a sustainable healthcare system within a super-aged society. Japan has pursued this goal through the implementation of community-based integrated care systems, the operation of a long-term care insurance system, the specialized training of primary care physicians, and the establishment of the “Comprehensive Medical Specialist” program. These initiatives aim to optimize the utilization of healthcare resources and ensure the long-term sustainability of the healthcare system. Japan’s experience offers critical insights for Korea, which requires effective strategies to strengthen its primary care system.

Japan has the highest proportion of older adults worldwide and has consistently strengthened its healthcare system to mitigate the medical and welfare burden associated with population aging. Primary care has been positioned as a key strategy for establishing a sustainable healthcare system within a super-aged society. Japan has pursued this goal through the implementation of community-based integrated care systems, the operation of a long-term care insurance system, the specialized training of primary care physicians, and the establishment of the “Comprehensive Medical Specialist” program. These initiatives aim to optimize the utilization of healthcare resources and ensure the long-term sustainability of the healthcare system. Japan’s experience offers critical insights for Korea, which requires effective strategies to strengthen its primary care system.

Serological prenatal screening tests are widely used to detect fetal chromosomal abnormalities such as Down and Edward syndromes. Amniocentesis is conducted as a confirmatory test in the screening-positive case. After discovering of presence of fetal cell-free DNA in maternal blood, non-invasive prenatal test (NIPT) coupled with next generation sequencing are performed in abroad. Results of genomics-based NIPT results supplied to Labgenomics laborotory from June, 2013 to August, 2014 were analyzed. Maternal blood samples were collected into specific Cell-Free DNA BCT tube and were transported. The samples were then delivered to Ariosa Diagnostics by FEDEX. Fetal cell-free DNA samples were analyzed using the Harmony test with sequencing of relevant chromosomes and by using the FORTE (fetal-fraction optimized risk of trisomy evaluation) algorism at Ariosa Diagnostics. In all, 149 cases from 28 medical clinics were analyzed. Six subjects were required recollection of samples because of a low fetal DNA fraction in the initially obtained samples. Of these 6 subjects, no sample could be collected from one. Of the remaining 148 cases, 144 had a low risk of trisomy, and 4 had a high risk for Down syndrome, thus providing a positivity percentage of 2.7%. Fetal DNA fraction in the maternal blood samples ranged from 4.2% to 23.7% with a mean value of 12.0%. We have experienced cases with a high risk for Down syndrome with genomics-based NIPT referred to abroad.
Amniocentesis ; Chromosome Aberrations ; DNA ; Down Syndrome ; Prenatal Diagnosis ; Trisomy

No abstract available.
Infection Control*

Hair follicle nevus is one of several nevi, in which hair and hair follicle are involved. Crowding of numerous tiny but mature hair follicles with thick fibrous root sheath are the characteristie histologic finding of the nevus. The patient was one month old male infant with pedunculated. mass l cm in size on the left preauricular area. Histologically the skin of the lesion is covered by acanthotic epidermis. In the corium are numerous small mature hair follicles with thick fibrous sheath and a few small Iobules of sebaceous gland embedded in a fibrovascular stroma. There are, however, no central plate of cartilage and adipose tissue.
Adipose Tissue ; Cartilage ; Crowding ; Dermis ; Epidermis ; Hair Follicle* ; Hair* ; Humans ; Infant ; Male ; Nevus* ; Sebaceous Glands ; Skin

Malignant acanthosis nigricans is very rare disease. The disease is related with internal malignancy, especially gastrointestinal tract malignancy. Reported occurrence rate of malignant acanthosis nigricans associated internal malignancies are 64% of stomach adenocarcinoma, 27% of other organs of abdomen (liver, gall bladder, small intestine, rectum, uterus, ovary), 9% of non-abdominal organs(breast, lung). We report a case of malignant acanthosis nigricans associated with stomach adenocarcinoma from 20-year-old female and discuss review of literature on a acanthosis nigricans briefly.
Female ; Humans ; Adenocarcinoma

Exogenous lipold pneumonia is an unusual disease resulting from aspiration of oil particles. A history of oil ingestion strongly suggests the diagnosis, but the radiological presentation varies from mild perihilar consolidation to diffuse and extensive bilateral involvement, particularly of the posterior basal segment of both lower lung(l). Since magnetic resonance(MR) provides greater contrast resolution than CT, it offers the potential for tissue characterization. In particular, fatty tissue and lipid containing substances are known to have high signal intensities on T1- and T2-weighted spin-echo (SE) images. We report MR findings in two case of exogenous lipold pneumonia caused by ingestion of shark liver oil(Squalene).
Adipose Tissue ; Diagnosis ; Eating ; Liver ; Pneumonia* ; Sharks