Prenatally diagnosed neuroblastomas have been reported in increasing numbers over the past several years. The vast majority are in favorable stages of the disease (stage I, II, IV-S). The authors experienced one case of stage IV-S neuroblastoma of the adrenal gland with liver metastasis, which regressed spontaneously after removal by adrenalectomy. This patient was noticed to have an abdominal mass at prenatal ultrasonography performed at 36weeks of gestation. This tumor was a neuroblastoma of the left adrenal gland with multiple liver metastases. Left adrenalectomy and liver biopsy were performed at 3 months of age. Thirty-eight months after surgery, an MRI demonstrated that the hepatic metastatic lesions had completely regressed without chemotherapy or radiation.
Adrenal Glands ; Adrenalectomy* ; Biopsy ; Drug Therapy ; Humans ; Liver* ; Magnetic Resonance Imaging ; Neoplasm Metastasis* ; Neuroblastoma* ; Pregnancy ; Prenatal Diagnosis ; Ultrasonography, Prenatal

No abstract available.
Breast* ; Child* ; Humans

No abstract available.
Cytogenetics*

No abstract available.
Nuchal Cord* ; Ultrasonography*

The infantile polycystic kidney disease is rare fetal urinary tract anomaly. It is inherited with an autosomal recessive pattern and recurrence rate is 25%. The gene locus is on chromosome 6p. The pathogenesis of infantile polycystic kidney is the primary defect of the collecting ducts. The ultrasonographic finding of infantile polycystic kidney is oligohydramnios, bilaterally symmetrical enlarged kidneys with maintenance of their reinform shape. The differential diagnosis with adult polycystic kidney disease is important. The massive enlargement of the kidneys is rarely seen in adult polycystic kidney disease and the examination of the parents and other members of the family is helpful to confirm the adult polycystic kidney disease. If there is severe renal involvements, stillbirth or neonatal death secondary to pulmonary hypoplasia would be developed. If it were diagnosed before viability, termination of pregnancy is recommended. In a fetus at risk, diagnosed after viability, pregnancy termination is also recommended since this condition is uniformly fatal. We present a case of infantile polycystic kidney.
Diagnosis, Differential ; Female ; Fetus ; Humans ; Kidney ; Oligohydramnios ; Parents ; Polycystic Kidney Diseases* ; Polycystic Kidney, Autosomal Dominant ; Pregnancy ; Recurrence ; Stillbirth ; Urinary Tract

Purpose: The purpose of our study is to examine early radiographic findings and clinical signs of failure of the microstructure surface HA-coated acetabular cup. Material and methods: This study included 41 revisions of 204 THA with hydroxyapatite-coated acetabular cup from April 1992 to November 1996. Radiolucent line around cups, change in the cup angle and osteolysis were evaluated in serial radiographs. Acetabular cup was defined as loosening if any movement occurred at the bone and socket interface by manual rotation and extension force intraoperatively or migration of more than 2 mm and change of the cup angle by more than 5 degrees in radiographs. Results: The radiolucent line was observed in 12 of the 41 hips at an average of 55.4 months postoperatively and was most commonly located in zone III. All of the 12 hips showing radiolucent lines were classified as loosening by radiographically in 8 cases and intraoperatively in 4 cases. Radiographic loosening occurred at an average of 28.8 months after the appearance of a radiolucent line. Inguinal pain was noted in 18 of the 19 cases revised for acetabular cup loosening. Conclusion: The most important radiographic finding for the early diagnosis of loosening was progressive radiolucent lines, which occurred most frequently in zone 3.
Acetabulum* ; Arthroplasty, Replacement, Hip ; Early Diagnosis ; Hip ; Osteolysis

No abstract available.
Pregnancy, Heterotopic*

No abstract available.
Female ; Fibronectins* ; Hypertension, Pregnancy-Induced* ; Plasma* ; Pregnancy ; Pregnancy*

The purpose of this study is to examine the cause of intrauterine fetal death by making a comparative analysis of the clinical difference between the pregnant women with such a case and those without it. For full seven years from January 1987 to December 1995, Moonwha Hospital saw 367 cases of intrauterine fetal death. Among them, selected for this study were the cases where at least 20 gestational weeks had passed since last menstrual period and the 127 cases where the measured fetal weight after delivery was 500 gm, and both cases were limited to those with exact records. Controls were the pregnant women who had given birth to normal fetuses during the above period. They were selected through random sampling and student t-test and x2-test were conducted for data analysis using SPSS PC ver 5.01 for Window. The findings are as follows: The prevalence of intrauterine fetal death was 1.09%. Its risk was about 3 times higher for the gravida under 25 and over 35. The frequency of intrauterine fetal death was statistically significant for nullipara(p=0.024). Cases showed noticeably frequent spontaneous abortion and induced abortion(p=0.020, p=0.029 each). Intrauterine fetal death rate was about 5 times higher in case delivery interval was one year or over 6 years. Sex ratio was found the same. Fifty percent of intrauterine fetal deaths happened within 28 weeks, while cases after term were only 5 percent. Unexplained cases topped the list of the causes, followed by congenital anomaly and then pregnancy-induced hypertension. Induced delivery took the greatest share of the whole delivery methods(82.7%), followed by spontaneous delivery(10.2%) and then laparotomy(7.1%). The conclusion is that proper antenatal care should be taken of fetuses on the basis of risk factors of antepartum and intrapartum so that unnecessary intrauterine fetal death can be prevented and furthermore pregnant women`s physical and mental pain can be reduced.
Abortion, Spontaneous ; Case-Control Studies* ; Female ; Fetal Death* ; Fetal Weight ; Fetus ; Humans ; Hypertension, Pregnancy-Induced ; Parturition ; Pregnancy ; Pregnant Women ; Prevalence ; Risk Factors ; Sex Ratio ; Statistics as Topic

Acardiac twinning affects 1 in 100 monozygotic twin pregnancies and 1 in 35,000 pregnancies overall. This condition is characterized by the absence or rudimentary development of fetal heart, and associated with various anomaly. The presence of an acardiac twin requires the normal (or "pump") twin to provide circulation for itself, as well as the acardiac sibling. The acardiac malformations are uniformly fatal in the affected twin, and mortality in the co-twin is as high as 55%. The principal perinatal problems associated with acardiac twinning are pump-twin congestive heart failure, maternal hydramnios, and preterm delivery. We recently experienced a case of acardius anceps associated with a normal male infant, so present with a brief review of the literature.
Fetal Heart ; Heart Failure ; Humans ; Infant ; Male ; Mortality ; Polyhydramnios ; Pregnancy ; Siblings ; Twins, Monozygotic