No abstract available.
Female ; Pregnancy ; Pregnancy, Ectopic*

No abstract available.
Female ; Pregnancy ; Pregnancy, Ectopic*

Bromidrosis is a disorder characterized by rancid body odor which influences a patient's social life and mental health. The therapeutic modalities and the mechanism of bromidrosis have been carefully studied, however, there have been few reports about the genetic inheritance of bromidrosis. We investigated the family history of 42 patients who were operated on for bromidrosis and followed up to the third generation in 10 cases. The results were as follows: Results of investigation which were followed up the second generation. The fathers of five patients and the mothers of 11 patients had bromidrosis in 18 male patients. The fathers of six patients and the mothers of 12 patients had bromidrosis in 24 female patients. Thirty-four patient (81.0%) among a total of 42 have a single parent with bromidrosis. Result of investigation which were followed up to the third generation Bromidrosis was occurred in 17 of 42 patients (40.5%) in the second generation, and 18 of 27 patients (66.7%) in the third generation. In one case, a father transmitted bromidrosis to his three sons, and as a result, X-linked inheritance could be ruled out Bromidrosis was not skipped in every generation of all families. We on conclude that bromidrosis is an autosomal dominant inherited disorder.
Fathers ; Female ; Genes, X-Linked ; Humans ; Male ; Mental Health ; Mothers ; Odors ; Single Parent ; Wills*

No abstract available.
Axis, Cervical Vertebra* ; Spondylolysis*

No abstract available.
Desmin* ; Intermediate Filament Proteins* ; Intermediate Filaments* ; Muscle, Skeletal* ; Muscular Diseases* ; Sciatic Nerve* ; Vimentin*

No abstract available.
Child* ; Humans

BACKGROUND: 'Tight junctions (TJ)' have recently been identified in the granular cell layer of the human epidermis, where they contribute to the normal adhesion between keratinocytes and to the physiologic barrier function of the epidermis. Among the TJ proteins in the epidermis, occludin is an important transmembrane protein, which is considered as a major component among the TJ. OBJECTIVE: The purpose of this study is to investigate whether regional variation exists in the expression of tight junction protein occludin in normal human epidermis. METHODS: The immunofluorescence staining for occludin was performed with specimens taken from different areas of normal skin (4 from each of 7 different anatomical sites, including the scalp, face, posterior neck, upper arm, abdomen, lower back, and inner thigh). The degrees of the expression-intensity in each specimen were estimated with the reciprocals of positive end-point titer of occludin in an immunofluorescence study. RESULTS: The highest degree expression-intensity of the TJ protein occludin among the different areas of normal epidermis was observed on the face and abdomen with a titer of 600. The lowest intensity of expression of occludin was seen in the epidermis from the upper arm. Skin specimens from the scalp, neck, back, and leg demonstrated intermediate degrees of the expression in intensity. CONCLUSION: The expression of occludin in the skin samples obtained from different locations of the body showed a statistically significant variation. This suggests that there is a certain degree of regional variation in the expression-intensity of TJ protein 'occludin' in the human epidermis.
Abdomen ; Arm ; Epidermis ; Fluorescent Antibody Technique ; Humans ; Keratinocytes ; Leg ; Neck ; Occludin ; Proteins ; Scalp ; Skin ; Tight Junctions

BACKGROUND: Nano-sized water particles have been thought to moisturize the skin more effectively. However, clear benefits of humidifier generating nano-sized water particles on the skin have not been studied. OBJECTIVE: The aim of this study is to examine the effects of humidifier generating nano-sized water particles on the skin by measuring the levels of the skin hydration state and skin barrier function with an objective, quantifiable method. METHODS: A 4-week, randomized, case-control study was conducted in 40 healthy Korean women, aged between 20 and 39, and they were divided into two groups, the experimental and control groups. The experimental group used humidifier generating nano-sized water particles for 8 hours every night, during 4 weeks. Skin hydration and transepidermal water loss (TEWL) were measured every week on the forehead and cheek using corneometer and tewameter, respectively. Safety evaluations were also performed at each visit. RESULTS: The baseline skin hydration and TEWL values showed no significant differences between the two groups. After 1 week of use, the experimental group showed significantly increased skin hydration values (p<0.001, p<0.0001) and decreased levels of TEWL values (p=0.017, p=0.025) as compared to the control group. During a 4-week study period, increased skin hydration and decreased TEWL were sustained in the experimental group. No adverse effects were observed in all the volunteers. CONCLUSION: These results show that humidifier, which generates nano-sized water particles, seems to positively affect skin hydration and skin barrier function. More studies and sufficient follow-up time are needed for the assessment of the humidifier generating nano-sized water particles.
Aged ; Case-Control Studies ; Cheek ; Female ; Follow-Up Studies ; Forehead ; Humans ; Skin ; Water

Periumbilical perforating pseudoxanthoma elasticum is a rare acquired disorder that usually occurs in obese, middle-aged, multiparous women. It is considered as a separate entity from the hereditary pseudoxanthoma elasticum due to lack of hereditary transmission and association with systemic disease. A 70-year-old multiparous woman presented with a 2-year history of a gradually enlarging, yellowish ulcerated plaque in the periumbilical region. The biopsy specimen showed irregularly altered elastic fibers with encrusted calcium salts that underwent transepidermal elimination. We report a rare case of periumbilical perforating pseudoxanthoma elasticum with no signs of hereditary pseudoxanthoma elasticum.
Aged ; Biopsy ; Calcium ; Elastic Tissue ; Female ; Humans ; Pseudoxanthoma Elasticum* ; Salts ; Ulcer