1.The influence of linoleic acid and ursolic acid on mouse peritoneal macrophage activity.
Joon Heon JEONG ; Kwang Hyuk KIM ; Myung Woong CHANG ; Sung Do LEE ; Jae Kwan SEO
Korean Journal of Immunology 1993;15(1):53-60
No abstract available.
Animals
;
Linoleic Acid*
;
Macrophages, Peritoneal*
;
Mice*
2.Etiologic Transition of Septic Arthritis of the Knee.
Seung Suk SEO ; Dong Jun HA ; Chang Wan KIM ; Kyoung Whan KIM ; Jin Hyuk SEO
Journal of the Korean Knee Society 2008;20(1):44-49
PURPOSE: The purpose of this study was to retrospectively analyze the etiologic transition of the predisposing factors and organisms for septic arthritis of the knee. MATERIALS AND METHODS: Between January 1995 and December 2006, 122 cases of septic arthritis of the knee were retrospectively evaluated for the etiologic transition and causative organism with using the patients' medical records. We researched the incidence and causative factor of septic arthritis of the knee, which was diagnosed via the patients' symptoms, physical examinations, hematologic exams, culture studies & cytology of the joint fluid. We assessed the correlation of disease with age, the year the disease happened, the causative factors and the incidence. RESULTS: Septic arthritis of the knee was increased after 40 years old, and it also increased after 1998. The most common predisposing factor was intra-articular injection of the knee joint. Even though there were no detected organisms in 79 cases (64.8%), the most common causative organism was S. aureus (20.5%). CONCLUSION: The most common etiologic factor of septic arthritis of the knee was an intra-articular injection. We should be prudent for using good aseptic technique and the correct procedure to reduce the secondary infection that's recently due to increased invasive treatment of the knee joint.
Arthritis, Infectious
;
Coinfection
;
Incidence
;
Injections, Intra-Articular
;
Joints
;
Knee
;
Knee Joint
;
Medical Records
;
Physical Examination
;
Retrospective Studies
3.Metastatic Osteosarcoma to the Prostate: A Case Report.
Hyoung Yeon SEO ; Jae Hyuk LEE ; Chang Soo PARK ; Jin Gyoon PARK ; Sung Taek JUNG
Korean Journal of Pathology 2009;43(5):475-477
The most common site for the metastasis of osteosarcoma is the lung, and other sites of metastases include the bone, lymph node, pleura and liver. Although unusual extrapulmonary metastases have been reported with the improvement of the therapeutic results for the primary lesions, they are exceptionally rare. We report here on a case of prostatic metastasis of an osteosarcoma of the proximal tibia, and this developed seven years after successful resection, and four years after resection of a pulmonary metastasis. Radical prostatectomy was performed, and histological examination demonstrated metastatic osteosarcoma. To the best of our knowledge, this is the first case of prostatic metastasis of osteosarcoma in the medical literature.
Liver
;
Lung
;
Lymph Nodes
;
Neoplasm Metastasis
;
Osteosarcoma
;
Pleura
;
Prostate
;
Prostatectomy
;
Tibia
4.Comparison between Steroid Injection and Stretching Exercise on the Scalene of Patients with Upper Extremity Paresthesia: Randomized Cross-Over Study.
Yong Wook KIM ; Seo Yeon YOON ; Yongbum PARK ; Won Hyuk CHANG ; Sang Chul LEE
Yonsei Medical Journal 2016;57(2):490-495
PURPOSE: To compare the therapeutic effects on upper extremity paresthesia of intra-muscular steroid injections into the scalene muscle with those of stretching exercise only. MATERIALS AND METHODS: Twenty patients with upper extremity paresthesia who met the criteria were recruited to participate in this single-blind, crossover study. Fourteen of 20 patients were female. The average age was 45.0+/-10.5 years and duration of symptom was 12.2+/-8.7 months. Each participant completed one injection and daily exercise program for 2 weeks. After randomization, half of all patients received ultrasound-guided injection of scalene muscles before exercise, while the other was invested for the other patients. RESULTS: After two weeks, there was a significant decrease of the visual analog scale score of treatment effect compared with baseline in both groups (6.90 to 2.85 after injection and 5.65 to 4.05 after stretching exercise, p<0.01). However, injection resulted in greater improvements than stretching exercise (p<0.01). The number of patients with successful treatment, defined as >50% reduction in post-treatment visual analog scale, was 18 of 20 (90.0%) after injection, compared to 5 of 20 (25.0%) after stretching exercise. There were no cases of unintended brachial plexus block after injection. CONCLUSION: Ultrasound-guided steroid injection or stretching exercise of scalene muscles led to reduced upper extremity paresthesia in patients who present with localized tenderness in the scalene muscle without electrodiagnostic test abnormalities, although injection treatment resulted in more improvements. The results suggest that symptoms relief might result from injection into the muscle alone not related to blockade of the brachial plexus.
Adult
;
Brachial Plexus/*drug effects
;
Cross-Over Studies
;
*Exercise Therapy
;
Female
;
Humans
;
*Injections, Intramuscular
;
Male
;
Middle Aged
;
Neck Muscles/drug effects
;
Pain/drug therapy
;
Pain Measurement
;
Paresthesia/*drug therapy/rehabilitation
;
Single-Blind Method
;
Thoracic Outlet Syndrome/diagnosis/*drug therapy
;
Treatment Outcome
5.Scar Revision with Frostbite Using Dry Ice.
Jin Hyuk PARK ; Choong Hyun CHANG ; Sang Won SEO ; Ji Young SONG
Journal of the Korean Society of Plastic and Reconstructive Surgeons 2004;31(1):144-148
Facial scar is one of the most common problems in plastic surgery department. Many various methods are attempted to improve facial scars, but there is no definite satisfactory method on scar revision. Authors have been interested in a tendency to show good results when traumatic lacerations were accompanied by abrasions. The improved appearance of the scars with this situation is the result that there were fewer elevations and depressions, and no break in continuity of the epidermal covering on both sides of the scar. But mechanical or other dermabrasive methods have a risk of hyperpigmentation. Authors suggest the scar revision with frostbite using dry ice. This method has little hyperpigmentation due to the sensitivity of melanocytes to cold injury. And the tissue destruction is progressed selectively because of the resistance of collagen against the cold injury and the preserved dermal fibrous network as the structural framework. These characteristics of cryotherapy improve the result of scar revision with fewer side effects rather than other dermabrasive methods. We performed this method to 349 patients from 1993 to 2003 and obtained high patients' satisfaction (85.9% more than fair). Moreover, this method is simple, cheap and handy. In conclusion, the scar revision with frostbite using dry ice is very useful method to improve facial scars.
Cicatrix*
;
Collagen
;
Cryotherapy
;
Depression
;
Dry Ice*
;
Frostbite*
;
Humans
;
Hyperpigmentation
;
Lacerations
;
Melanocytes
;
Surgery, Plastic
6.The Efficacy of the EORTC Scoring System and Risk Tables for the Prediction of Recurrence and Progression of Non-Muscle-Invasive Bladder Cancer after Intravesical Bacillus Calmette-Guerin Instillation.
Kyung Won SEO ; Byung Hoon KIM ; Choal Hee PARK ; Chun Il KIM ; Hyuk Soo CHANG
Korean Journal of Urology 2010;51(3):165-170
PURPOSE: The European Organization for Research and Treatment of Cancer (EORTC) scoring system and risk table were introduced in the 2008 European Association of Urology guidelines on TaT1 bladder cancer. We compared the recurrence and progression rate between EORTC risk tables and author's patients who underwent transurethral resection of bladder cancer (TURB) following intravesical Bacillus Calmette-Guerin (BCG) instillation. MATERIALS AND METHODS: The medical records of 251 patients who underwent TURB and were diagnosed with non-muscle-invasive bladder cancer from l993 to 2007 were analyzed. The patients were divided into 2 groups: the recurrence group and the progression group. According to the EORTC scoring system, the patients in each group were categorized in terms of number of tumors, tumor size, prior recurrence rate, T category, carcinoma in situ, and pathologic grade and the scores were summed. According to the summed scores, the recurrence group and the progression group were divided into 3 subgroups: low, intermediate, and high risk, respectively. The recurrence rate and progression rate of each group were compared with the EORTC risk tables. RESULTS: The recurrence rate and progression rate were almost similar to the EORTC risk tables. However, the recurrence rate was low in the intermediate-risk group. CONCLUSIONS: Clinical utilization of the EORTC scoring system and risk tables is very effective in predicting the recurrence and progression of non-muscle-invasive bladder cancer and in selecting treatment.
Bacillus
;
BCG Vaccine
;
Carcinoma in Situ
;
Humans
;
Medical Records
;
Recurrence
;
Urinary Bladder
;
Urinary Bladder Neoplasms
;
Urology
7.A Case of Uterine Rupture in Pregnancy Complicated with Myelodysplastic Syndrome.
Byeong Do LIM ; Hyuk Woo LEE ; Sung Hong JOO ; Eui Sik JUNG ; Chang Seo PARK ; Sung Jin CHO
Korean Journal of Obstetrics and Gynecology 2002;45(2):327-331
Myelodysplastic syndrome (MDS) is a relatively uncommon hematological disorder, charactedzed by cytopenia in the peripheral blood and normo-or hypercellularity in the bone marrow with morphological dysplastic change. Ineffective hematopoiesis leads to hematological failures in this syndrome. MDS is largeIy affected in older individuaIs with a median age of 60-75. It's association with pregnancy is even rarer. Although the exact incidence of MDS in pregancy is unknown, it is likely to be less than 1 per 100,000 pregnancies annually. Recently, we experienced a case of MDS presented initially during pregnancy in a 34-year-old primipara and managed with intensive hematologic support. Uerine rupture occurred in pregnancy complicated with MDS at 34 gestation weeks and a healthy infant was successfully delivered by Cesarean section. We report this case with a brief review of the literature.
Adult
;
Bone Marrow
;
Cesarean Section
;
Female
;
Hematopoiesis
;
Humans
;
Incidence
;
Infant
;
Myelodysplastic Syndromes*
;
Pregnancy*
;
Rupture
;
Uterine Rupture*
8.A Case of Uterine Rupture in Pregnancy Complicated with Myelodysplastic Syndrome.
Byeong Do LIM ; Hyuk Woo LEE ; Sung Hong JOO ; Eui Sik JUNG ; Chang Seo PARK ; Sung Jin CHO
Korean Journal of Obstetrics and Gynecology 2002;45(2):327-331
Myelodysplastic syndrome (MDS) is a relatively uncommon hematological disorder, charactedzed by cytopenia in the peripheral blood and normo-or hypercellularity in the bone marrow with morphological dysplastic change. Ineffective hematopoiesis leads to hematological failures in this syndrome. MDS is largeIy affected in older individuaIs with a median age of 60-75. It's association with pregnancy is even rarer. Although the exact incidence of MDS in pregancy is unknown, it is likely to be less than 1 per 100,000 pregnancies annually. Recently, we experienced a case of MDS presented initially during pregnancy in a 34-year-old primipara and managed with intensive hematologic support. Uerine rupture occurred in pregnancy complicated with MDS at 34 gestation weeks and a healthy infant was successfully delivered by Cesarean section. We report this case with a brief review of the literature.
Adult
;
Bone Marrow
;
Cesarean Section
;
Female
;
Hematopoiesis
;
Humans
;
Incidence
;
Infant
;
Myelodysplastic Syndromes*
;
Pregnancy*
;
Rupture
;
Uterine Rupture*
9.Detection and Isolation of Genital Mycoplasmas from Public Toilet Bowls.
Je Wook YEON ; Myoung Woong CHANG ; Kwang Hyuk KIM
Journal of Bacteriology and Virology 2002;32(3):231-238
Genital mycoplasmas are sexually transmitted. There are considerable public concern that causative agents of sexually transmitted diseases might be transmitted nonsexually through public restrooms. In the present study, Mycoplasma hominis, Ureaplasma urealyticum and M. penetrans among genital mycoplasmas were identified in 100 public restroom toilet bowls (50 men's and 50 women's public restrooms, each). Mycoplasmas were genotypically identified by two methods; (1) PCR of primary selective culture and (2) direct PCR of original specimens before primary selective culture. From 50 men's public restrooms, M. hominis, U. urealyticum and M. penetrans were identified from PCR of primary selective cultures in 6%, 4% and 0% of the specimens, respectively and M. hominis and U. urealyticum was codetected in 2% of those. And M. hominis, U. urealyticum and M. penetrans were identified by direct PCR in 20%, 16% and 0% of the original specimens, respectively and co-detection rate of M. hominis and U. urealyticum was 4% in those. From 50 women's public restrooms, 38% was positive for M. hominis, 14% for U. urealyticum, 0% for M. penetrans and 10% for both U. urealyticum and M. penetrans by PCR of primary selective culture. And 50% was positive for M. hominis, 46% for U. urealyticum and 0% for M. penetrans and 34% for both M. hominis and U. urealyticum by direct PCR of the original specimens. These results indicate that the genital mycoplasmas can survive for considerable duration in toilet bowels, and might be transmitted by through public restrooms.
Mycoplasma hominis
;
Mycoplasma penetrans
;
Mycoplasma*
;
Polymerase Chain Reaction
;
Sexually Transmitted Diseases
;
Ureaplasma urealyticum
10.Granular Cell Tumor in the Pituitary Stalk: A Case Report.
Soo Jeong PARK ; Youn Hyuk CHANG ; Na Rae YANG ; Eui Kyo SEO
Brain Tumor Research and Treatment 2015;3(1):60-63
Granular cell tumors (GCTs) have been reported in various tissues, especially the skin and subcutaneous soft tissue of the head and neck. We report a 60-year-old man who presented with intermittent headache and dizziness for 3 months, but no other neurological symptoms. Magnetic resonance imaging (MRI) showed the presence of a mass in the pituitary stalk, and contrast-enhanced MRI showed nodular enhancement in this region. The lesion was completely excised microscopically via a frontotemporal (pterional) approach. On pathological examination, a final diagnosis of a typical GCT was made.
Diagnosis
;
Dizziness
;
Granular Cell Tumor*
;
Head
;
Headache
;
Humans
;
Magnetic Resonance Imaging
;
Middle Aged
;
Neck
;
Pituitary Gland*
;
Pituitary Neoplasms
;
Skin