PURPOSE: To evaluated the usefulness of pressure-flow study (PFS) as a preoperative technique, and to compare its sensitivity and specificity, with uroflow, post void residual urine and prostate volume, in benign prostatic hyperplasia patients. MATERIALS AND METHODS: The records of 109 men, with lower urinary tract symptoms that underwent a transurethral resection of prostate (TURP), between May 1995 and June 2002, were retrospectively analyzed. Fifty one patients underwent preoperative PFS and 58 did not. The PFSs were performed with an 8Fr suprapubic catheter. The results of the PFS were divided into two groups: obstructed and unobstructed, using an ICS nomogram, pQ slope or the minimal urethral opening pressure. The outcomes of the operations were estimated with IPSS and the maximal flow rate 3 month after the operations. RESULTS: With the PFS operations, 47 cases (81.0%) were obstructed and 11 (19.0%) unobstructed. The success rates of the TURP for the obstructed, unobstructed and non-invasive study groups were 87.2, 63.6 and 88.2%, respectively. The sensitivity and specificity of the PFS were 84.5 and 40.4%, respectively. The sensitivity of the maximal flow rate (or=30gm) was 50.0%. CONCLUSIONS: PFS is not a mandatory preoperative technique for men, with lower urinary tract symptoms, who undergo a TURP. However, it can decrease the TURP failure rate. Other noninvasive parameters can be preoperatively useful for men who undergo TURP, as long as they are applied compositely carefully.
Catheters ; Humans ; Lower Urinary Tract Symptoms ; Male ; Nomograms ; Prostate ; Prostatic Hyperplasia* ; Retrospective Studies ; Sensitivity and Specificity ; Transurethral Resection of Prostate ; Urodynamics

No abstract available.
Stomach Neoplasms*

BACKGROUND: The human homologue of the SC2 gene from a human dermal papilla cell cDNA library has been isolated and designated hSC2. HSC2 protein also shares similarity with 5 -reductase, a protein important in testosterone metabolism. OBJECTIVE: Prior to knowing the functions of hSC2 in dermal papilla, we cloned it and analyzed its relative expression levels in adult tissues and cancer cell lines. METHODS: hSC2 was isolated from low abundant clones in dermal papilla cDNA library using cDNA array hibridization method. Full-length clone was sequenced and we studied its expression in different tissues by Northern blot hybridization. RESULTS: Sequence data reveals a single open reading frame, encoding a putative hydrophobic protein with a calculated molecular weight of 36 kDa. Its deduced amino acid sequences are almost 97.4% identical to t4ose of rat protein. Northern blot hybridization shows that hSC2 cDNA recognizes a 1.35 kb transcript that was expressed in various epithelial and mesenchymal tissues including testis and liver. CONCLUSION: We have cloned and analysed tissue distributions of hSC2. It was interesting that it had homology with 5α-reductase isozymes. Further studies will be needed to understand the involvement of hSC2 in androgen hormone signaling.
Adult ; Amino Acid Sequence ; Animals ; Blotting, Northern ; Cell Line ; Clone Cells ; Cloning, Molecular* ; DNA, Complementary ; Gene Library ; Humans ; Isoenzymes ; Liver ; Metabolism ; Molecular Weight ; Oligonucleotide Array Sequence Analysis ; Open Reading Frames ; Rats ; Testis ; Testosterone ; Tissue Distribution

BACKGROUND: Contact immunotherapy using diphenylcyclopropenone (DPCP) has been used in the treatment of alopecia and warts. DPCP seemed to be a promising agent for viral disease including molluscum contagiosum (MCI). OBJECTIVE: The purpose of this study was to evaluate the effect of DPCP immunotherapy on MC in children. METHODS: Twenty three patients with multiple lesion of MC were treated with DPCP immunotherapy. RESULTS: Twelve patients (52.2%) showed cure, and eleven patients (47.8%) showed treatment failure. No severe side effects were seen. CONCLUSION: DPCP immunotherapy may be an effective treatment in children with MC without serious side effects.
Alopecia ; Child ; Humans ; Immunotherapy* ; Molluscum Contagiosum* ; Treatment Failure ; Virus Diseases ; Warts

No abstract available.

No abstract available.
Child* ; Graves Disease* ; Humans

Migratory birds have been suspected as playing a central role in transmission of various trematodes, but few surveys have been undertaken in the Republic of Korea. In the present study, we describe new fauna of microphallid flukes in Korea. Two species of microphallids were found in the intestines of 2 migratory bird species, namely the red necked stints (Calidris ruficollis) and the terek sandpiper (Xenus cinereus), in a coastal area of Gunsan-si, Jeollabuk-do. The microphallids recovered from the latter were 451 microm in length and 217 microm in width, and the eggs were very small, 13 microm by 8 microm. They had the characteristic extracecal vitellaria intruding into the median posttesticular area, belonging to Endocotyle incana. Another microphallids were discovered from both migratory birds, 417 microm in length and 249 microm in width. The cirrus was projecting into the genital atrium in form of male papilla, and bounded by a muscular flap, termed pseudogonotyl. They were identified as Spelotrema pseudogonotyla in consideration of the distinctive male papilla and pseudogonotyl. Besides these flukes, Maritrema obstipum and Gynaecotyla squatarolae also were recovered. This paper is in fact the first report on the presence of Spelotrema and Endocotyle in Korea.
Animals ; Bird Diseases/*parasitology ; Charadriiformes/*parasitology ; Microscopy ; Republic of Korea ; Trematoda/anatomy & histology/*classification/*isolation & purification ; Trematode Infections/parasitology/*veterinary ; Zygote

No abstract available.

No abstract available.
Mandibular Reconstruction*

We performed a case of ureteroileocecal sigmoidostomy in a 56-year-old female patient who had transitional cell carcinoma of the bladder(pT3aNoMo, grade III, mutiple, papillary). Both ureters were anastomosed to the ileal end of the ileocecal segment and colonic end was anastomosed to the J pouch of the sigmoid colon. At 7 months postoperatively, the intraluminal pressure of the pouch is 20 cmH2O in supine position, 40 cmH2O in sitting or squatting position, 90-100 cmH2O on voiding. No visible reflux of fecal and urinary stream into upper urinary tract was observed on both antegrade and retrograde pouchgraphy. No ectatic changes of upper urinary tract was seen on excretory urography until 36 months postoperatively. There was no changes in CBC, liver function, renal function and serum electrolytes. Even though there had been no febrile attack without any antibiotic medications during follow-up period, bilateral renal scarring was observed on CT films of postoperative 24 months. Continuous suppressive dose of sulfamethoxazole- trimethoprim was started. She passes urine in diarrhea pattern every three to four hours and has no leakage in night time. She satisfies with status of voiding at present after 30 months postoperatively. No visible reflux into upper urinary tract from the pouch is identified, ascending infection could not be prevented by this antireflux method only. This procedure can be an alternative way of urinary diversion in the era of bladder substitution if ascending infection can be prevented by enforced and more secure procedures to prevent reflux are added.
Carcinoma, Transitional Cell ; Cicatrix ; Colon ; Colon, Sigmoid* ; Colonic Pouches* ; Diarrhea ; Electrolytes ; Female ; Follow-Up Studies ; Humans ; Liver ; Middle Aged ; Rivers ; Supine Position ; Trimethoprim ; Ureter ; Urinary Bladder ; Urinary Diversion ; Urinary Tract ; Urography