No abstract available.
Carboxylesterase* ; Leukemia, Promyelocytic, Acute*

No abstract available.
Agenesis of Corpus Callosum

Adenomyoepithelioma is a rare benign tumor which occurs mainly in the skin, salivary gland and very rarely in the breast. Histologically this tumor demonstrates biphasic differentiation of luminal epithelial cells and myoepithelial cells. We report a case of adenomyoepithelioma occuring in the outer lower quadrant of the right breast of a 56-year-old female, confirmed histologically with an aid of immunohistochemistry. This is the first documented report in Korean literature.
Adenomyoepithelioma* ; Breast* ; Epithelial Cells ; Female ; Humans ; Immunohistochemistry ; Middle Aged ; Phenobarbital ; Salivary Glands ; Skin

No abstract available.
Neoplasm Metastasis*

BACKGROUND: Tuberculous lymphadenitis is the commonest form of extrapulmonary tuberculosis. The laboratory diagnosis of tuberculous lymphadenitis is based on the traditional method of the acid-fast stain and culture of discharge or lymph node. However, acid-fast stain lack sensitivity and specificity, and culture is time- consuming. Polymerase chain reaction is a rapid, sensitive and specific DNA amplification technique for the detection of Mycobacterium tuberculosis in sputum, pleural fluid, cerebrospinal fluid, or others. We evaluate the sensitivity and specificity of the polymerase chain reaction assay for the rapid diagnosis of tuberculous lymphadenitis. METHODS: This study included 50 patient with clinically suspected tuberculous lymphadenitis. We performed fine needle aspiration biopsies (FNAB) on head and neck lymph node. The DNA of the sample was purified by phenol/chloroform method. The nested PCR was performed with TB-CR kit (Bioneer, Korea), which an amplified an insertion sequence IS 6110 sequences. The PCR product was analyzed by agarose gel electrophoresis in the presence of ethidium bromide. RESULTS: Forty-five of the 50 clinically suspected specimens were PCR-positive, five specimens were negative. And one of the 10 negative specimens was positive. The sensitivity and specificity of the PCR was 90% and 90%, respectively. CONCLUSION: The polymerase chain reaction is a very sensitive and rapid method for rapid detection of M. tuberculosis in patients with tuberculous lymphadenitis.
Biopsy ; Biopsy, Fine-Needle ; Cerebrospinal Fluid ; Clinical Laboratory Techniques ; Diagnosis* ; DNA ; Electrophoresis, Agar Gel ; Ethidium ; Head ; Humans ; Lymph Nodes ; Lymphadenitis ; Mycobacterium tuberculosis ; Neck ; Nucleic Acid Amplification Techniques ; Polymerase Chain Reaction* ; Sensitivity and Specificity ; Sputum ; Tuberculosis ; Tuberculosis, Lymph Node*

No abstract available.
Humans ; Male*

PURPOSE: The aim of this study was to examine the health-related behaviors related to a family history of cancer (FHCA) among Korean women underwent cancer screening. MATERIALS AND METHODS: A total of 8,956 women who underwent cancer screenings during 2001-2011 at the National Cancer Center, Korea, were analyzed. The association between health-related behaviors and a FHCA were assessed using multivariate logistic regression. RESULTS: Compared to women with no FHCA, women with FHCA were more likely to smoke (adjusted odds ratio [aOR], 1.32; 95% confidence interval [CI], 1.06 to 1.65), to be exposed to passive smoking (aOR, 1.21; 95% CI, 1.15 to 1.65), and less likely to engage in regular exercise (aOR, 1.20; 95% CI, 1.01 to 1.41). Combined effects of selected health behaviors for FHCA were significant, although no statistically significant interactions were observed between selected health behaviors. Compared to women with no FHCA, women with FHCA were more likely to simultaneously smoke and be exposed to passive smoking (aOR, 1.65; 95% CI, 1.17 to 2.31) and to simultaneously smoke and be physically inactive (aOR, 1.62; 95% CI, 1.00 to 2.64). CONCLUSION: The study found that women with a FHCA exhibited unhealthy behaviors compared to women without FHCA. Higher emphasis on lifestyle modifications using a new standardized tool is strongly recommended for those with a FHCA, as well as individuals who are at high risk, together with their family members.
Early Detection of Cancer ; Female ; Health Behavior* ; Humans ; Korea ; Life Style ; Logistic Models ; Mass Screening ; Odds Ratio ; Smoke ; Tobacco Smoke Pollution

BACKGROUND: Extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae are main pathogens of bloodstream infection. We compared the epidemiology of ESBL-producing E. coli and K. pneumoniae. METHODS: From January 2003 through March 2007, we retrospectively investigated the clinical characteristics and comorbidities of patients with bloodstream infection by ESBL-producing E. coli and K. pneumoniae. RESULTS: During the study period, 79 patients (54 with E. coli and 25 with K. pneumoniae) with blood cultures positive for ESBL-producing E. coli or K. pneumoniae were studied. When comparing the source of bloodstream infections, urinary tract infections (UTIs) were more commonly caused by E. coli (24% vs. 0; P=0.007), and respiratory tract and soft tissue infection (36% vs. 15%; P=0.04, 12% vs. 0; P=0.03, respectively) were more commonly associated with K. pneumoniae. Among hospital-acquired bloodstream infection, third-generation cephalosporin was more commonly used in patients with E. coli than patients with K. pneumoniae (81% vs. 24%, P<0.001). Medical devices (central venous catheter and urinary catheter) were more commonly used in patients with K. pneumoniae. CONCLUSION: ESBL-producing E. coli bloodstream infection is more common in urinary tract infections. ESBL-producing K. pneumoniae is more common in respiratory tract infections and in skin and soft tissue infections. In hospital-acquired infections, ESBL-producing E. coli bloodstream infection is more common in biliary tract infection. ESBL-producing E. coli was more commonly associated with prior frequent antibiotics use and K. pneumoniae was more commonly associated with use of medical devices.
Anti-Bacterial Agents ; beta-Lactamases ; Biliary Tract ; Catheters ; Comorbidity ; Epidemiology* ; Escherichia coli* ; Humans ; Klebsiella pneumoniae* ; Pneumonia ; Respiratory System ; Respiratory Tract Infections ; Retrospective Studies ; Skin ; Soft Tissue Infections ; Urinary Tract Infections