Objective To investigate the clinical significance of plasma NO,NOS and MMP-9 variences in patients with cervical cancer. Methods 69 cervical cancer patients were studied. Patients with cervical cancer, 1 day before surgery,after 15 days,30 days of fasting peripheral,and healthy control group with fasting blood,venous blood drawn respectively. Plasma NO, NOS and MMP-9 levels were detected by chemical assay and ELISA assay. Comparing the changes in these indicators and their correlation. Results Compared with healthy control group,plasma NO, NOS,MMP-9 levels were significant higher in cervical cancer patients. Compared to before surgery,the plasma NO, NOS,MMP-9 were significantly lower in surgery after 15 days,30 days,but still significantly higher than normal. Patients with cervical cancer with lymph node metastasis NO, NOS, MMP-9 levels were significantly higher than those without lymph node metastasis,correlation analysis showed that serum MMP-9 and NO,NOS had significant positive correlation. Conclusion Detection of plasma NO, NOS and MMP-9 levels, it was better to evaluate the condition of cervical cancer and serve guidelines of clinical treatment.

Objective To screen the abnormal glucose metabolism in pregnant women without diabetes and to give early intervention to reduce perinatal maternal and fetal adverse complications.Methods 2 579 pregnant women who received obstetric examination and revealed no diabetes,underwent GCT screening and OGTr reexamination.The results confirmed the 263 GIGT patients,22 GDM patients.They were givien intervention therapy until delivery and their pregnancy outcome was compared with the normal pregnant women.Results The pregnancy outcome of GIGT pregnant women received intervention and the normal pregnant women had no significant difference.The incidence rates of macrosomia and cesarean section in GDM group were higher than those of normal pregnant women (P ＜0.05,P ＜ 0.01).Conclusion Development of gestational abnormal glucose tolerance screening is important to the early diagnosis and intervention of potential IGT,GDM patients,which can significantly reduce the incidence rate of maternal and fetal adverse complications.

Objective To investigate a wide range of uterine cervical cancer after hysterectomy for lower urinary tract urinary dynamics characteristics.Methods Cervical cancer Ib Ⅱ a via ablominal extensive hysterectomy in 25 cases were analyzed retrospectively,which had the type of operation in 7 cases,type Ⅲ Procedures for 18 cases,respectively,at 1 month after operation and 1 urethral urodynamic studies.Results The patients showed varying degrees of voiding dysfunction and urine storage dysfunction,maximum urinary flow rate decreased significantly (10.01 ml/min),the average decrease in urinary flow rate(6.44ml/min),voiding time 77.63s,residual urine volume 103.16ml,maximum bladder capacity 288.68ml,postoperative beard had the aid of abdominal pressure urination.Conclusion Extensive hysterectomy can occur after different degree of voiding dysfunction and urine storage dysfunction,and duration is longer,the main manifestation of impaired detrusor function,bladder sensory dysfunction,urethral dynamics can contribute to early diagnosis,early treatment,to prevent serious complications of the urinary system.