We studied the refractive state of 1440 eyes, 720 children (360 boys and girls in each) of T primary school in Busan and 720 eyes, 360 children (186 boys and 174 girls) of S primary school in Geu-Chang, Keung Nam. We neglected small refractive errors up to 0.5 Diopter because there was mathematical error in spite of exact clinical measurement of ocular refractive powerunder cycloplegia. The results were as follows: 1. Incidence of refractive errors of children (7 to 12 years) was 37.7 and 27.8% in T and S primary school respectively. 2. Incidence of myopic eyes was 25.6 and 13.6% in T and S primary school but that of hyperopic eyes was 11.7 and 14.2% respectively. Incidence of refractive errors and myopic eyes of children between T and S primary school showed significant difference. 3. The greatest incidence of refractive errors was at the age of 7 years but there was no significant difference at the age of 8 to 12 years. 4. The degree of refractive power of children in T and S primary school was 95.9 and 96.1% of hyperopia and 74.5 and 83% of myopia under 1.0 Diopter respectively. 5. Incidence and the degree of refractive power in myopia showed tendency of an increase in proportion to the age of 8 to 12 years. 6. The incidence of myopic eyes was not related to body weight and height of children of both sex.
Body Weight ; Busan ; Child* ; Female ; Humans ; Hyperopia ; Incidence ; Myopia ; Refractive Errors

Mucopolysaccharidosis (MPS) and mucolipidosis(ML) belong to a group of rare genetic disorders of lysosomal enzymes and share some clinical manifestations. MPS is characterized by the accumulation of glycosaminoglycans (GAG) and results from the impaired function of one of 11 enzymes required for normal GAG degradation. ML, which is clinically similar to several forms of MPS, is caused by deficiency of Nacetylglucosamine-1-phosphotransferase activity. Therapeutic strategies for MPS, including enzyme replacement therapy and bone marrow transplantation, have been developed with some success. In this review, we discuss clinical feature, diagnostic methods, management and the present status of research on MPS and ML.
Bone Marrow Transplantation ; Enzyme Replacement Therapy ; Glycosaminoglycans ; Mucolipidoses* ; Mucopolysaccharidoses*