Seminoma is one of the most radiosensitive solid tumors. However, the survival of patients with clinically advanced stages B3 and C disease is poor. Most of the failures of treatment in advanced stage seminoma, however, come from systemic diseases outside radiation fields or are secondary to unrecognized non-seminomatous elements. Therefore adjuvant systemic chemotherapy is essential for proper treatment of three patients. Recently we experienced a case of advanced stage seminoma treated with radical inguinal orchiectomy followed by systemic chemotherapy with good result.
Drug Therapy ; Humans ; Orchiectomy ; Seminoma*

A case of seminoma of the cryptorchism, found in 34 years old Korean male is reported. In Campbell's series, the incidence of malignancy in cryptorchism is claimed to be 35 times greater than in the normally descended testicle. A case of seminoma of the cryptorchism is added to literature.
Adult ; Cryptorchidism* ; Humans ; Incidence ; Male ; Seminoma* ; Testis

Although testicular tumor were reported sporadically in Korea malignant tumors developed in bilateral cryptorchidism were rarely seen in the literature. Seminoma is the most frquent tumor of the testis. Here, we report a rare case of seminoma developed in cryptorchid testis of a 32 years old male and relevant literatures have been reviewed.
Adult ; Cryptorchidism ; Humans ; Korea ; Male ; Seminoma* ; Testis*

A case of 24 years old Korean soldier who seminoma of right testis was presented. Literature was also briefly reviewed.
Humans ; Military Personnel ; Seminoma* ; Testis ; Young Adult

Malignant lymphoma of the testis is a rare disease and the most common testicular tumor in patients more than 60 years old. Malignant lymphoma of the testis is frequently confused with seminoma. In fact, only 30%, of patients in one series had disease-free intervals greater than 6 months postorchiectomy, and 90% of these parients died of generalized lymphoma within 2 years. We report a case of malignant lymphoma of the testis developed in a 55 years old man.
Humans ; Lymphoma* ; Middle Aged ; Rare Diseases ; Seminoma ; Testis

Seminomatous testis tumors are treated highly effectively with irradiation and chemotherapy following orchiectomy according to stage. We report a relatively rare case of seminoma developed in abdominal cryptorchid testis of 35 years old man, which was treated with surgery including the segmental resection of sigmoid colon involved.
Adult ; Colon, Sigmoid ; Drug Therapy ; Humans ; Orchiectomy ; Seminoma* ; Testis*

We recently encountered a very rare case of torsion of an intrascrotal testicular tumor in a 26-year-old male. Unlike the intra-abdominal undescended testis, intrascrotal spermatic cord torsion associated with a testicular tumor has rarely been reported. We write to report a case of intrascrotal spermatic cord torsion accompanied by a testicular tumor that had been overlooked preoperatively.
Adult ; Cryptorchidism ; Humans ; Male ; Seminoma ; Spermatic Cord ; Spermatic Cord Torsion

A 36-year-old man was studied because of signs and symptoms of superior vena naval syndrome. Chest computerized topography showed 10x8x6 cm sized lobulated anterior mediastinal mass, compressing superior vena casa. Fine needle aspiration cytology revealed seminoma. There was no detectable tumor mass in the testes. We report a case of primary mediastinal seminoma presenting with superior vena canal syndrome.
Adult ; Biopsy, Fine-Needle ; Humans ; Mediastinum ; Seminoma ; Testis ; Thorax

Recurrence of seminoma in the scrotum after inguinal orchidectomy is extremely rare. Herein, we report the second case in the literature of recurrence of seminoma in the scrotum following inguinal orchidectomy for stage I seminoma.
Seminoma ; Recurrence ; Disease of scrotum ; Benign neoplasm of scrotum ; Orchiectomy

OBJECTIVETesticular mixed nonseminomatous germ cell cancer (TMNGCC) is rarely reported. This study aimed to explore the clinical symptoms, pathological characteristics and treatment methods of TMNGCC.

METHODSWe analyzed the clinical data of 1 case of TMNGCC, observed its pathological characteristics under the light microscope by histology, cytochemistry, immunohistochemistry and immune marking, and investigated the clinical features of such tumors by reviewing the relevant literature.

RESULTSThe patient presented with a chief complaint of painless testicular swelling for 3 years. Histopathological examinations revealed a tumor of papillary, fissural or adenoid structure, with large polygonal or columnar cells with one or more irregular vesicular nuclei, the nuclear membrane clear, the cytoplasm eosinophilic or basophilic, and the interstitium infiltrated by a few lymphocytes. Here are the immunohistochemical results: CD117 -, CK8-18 + +, CD30 + +, CK + + +, vimentin -, PLAP +/-, P53 +, AFP + and EMA + +. The tumor was pathologically diagnosed as teratogenic embryonic testicular cancer, and treated by radical surgery, followed by adjuvant chemotherapy according to the treatment of TMNGCC. One-year follow-up found the patient to be alive.

CONCLUSIONTMNGCC is a rare malignant tumor, mostly with unobvious clinical symptoms. Its diagnosis primarily depends on physical examination, ultrasonography, CT, and measurement of serum tumor markers; its confirmation necessitates pathological examination, and its first-choice treatment is surgical resection.